| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Avi E Zayara, Gregor McIver, Paola N Valdivia, Kevin D Lominac, Andrew C McCreary, Karen K Szumlinsk. Blockade of nucleus accumbens 5-HT2A and 5-HT2C receptors prevents the expression of cocaine-induced behavioral and neurochemical sensitization in rats. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:20814782. |
the serotonin 5-ht(2a) and 5-ht(2c) receptors regulate the capacity of acute cocaine to augment behavior and monoamine levels within the nucleus accumbens (nac), a brain region involved in cocaine's addictive and psychotogenic properties. |
2011-05-24 |
2023-08-12 |
rat |
| Charlotte Wiker, Love Linnér, Marie-Louise Wadenberg, Torgny H Svensso. Adjunctive treatment with mianserin enhances effects of raclopride on cortical dopamine output and, in parallel, its antipsychotic-like effect. Neuropsychiatric disease and treatment. vol 1. issue 3. 2011-05-17. PMID:18568103. |
here, we have examined the effect of mianserin in combination with the selective dopamine (da) d(2/3) receptor antagonist raclopride on conditioned avoidance response (car), a preclinical test of antipsychotic efficacy with high predictive validity; catalepsy, a preclinical test of extrapyramidal side effect liability; and da output in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), respectively. |
2011-05-17 |
2023-08-12 |
rat |
| Hong Nie, Mridula Rewal, T Michael Gill, Dorit Ron, Patricia H Jana. Extrasynaptic delta-containing GABAA receptors in the nucleus accumbens dorsomedial shell contribute to alcohol intake. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 11. 2011-05-16. PMID:21368141. |
we used the technique of viral-mediated rnai to reduce expression of the gaba(a) receptor δ-subunit in adult rats in localized regions of the nucleus accumbens (nac) to test the hypothesis that δ-subunit-containing gaba(a) receptors in the nac are necessary for oral alcohol consumption. |
2011-05-16 |
2023-08-12 |
rat |
| V Valentini, R Frau, F Bordi, F Borsini, G Di Chiar. A microdialysis study of ST1936, a novel 5-HT6 receptor agonist. Neuropharmacology. vol 60. issue 4. 2011-05-12. PMID:21185318. |
here we report the effect of st1936 (5-10-20 mg/kg/ip) on dialysate da, na and 5-ht in the medial prefrontal cortex (pfcx) and in the shell and core of the nucleus accumbens (nac). |
2011-05-12 |
2023-08-12 |
Not clear |
| Kyohei Mori, Juhyon Kim, Kazuo Sasak. Electrophysiological effects of orexin-B and dopamine on rat nucleus accumbens shell neurons in vitro. Peptides. vol 32. issue 2. 2011-05-05. PMID:21055430. |
the mesolimbic dopamine (da) pathway that projects into the nucleus accumbens (nac) from the ventral tegmental area is deeply involved in the neural mechanisms underlying reward, drug abuse and motivation. |
2011-05-05 |
2023-08-12 |
rat |
| A J D Nelson, K E Thur, R R Horsley, C Spicer, C A Marsden, H J Cassada. Reduced dopamine function within the medial shell of the nucleus accumbens enhances latent inhibition. Pharmacology, biochemistry, and behavior. vol 98. issue 1. 2011-05-04. PMID:21146557. |
experiment 1 tested whether 6-hydroxydopamine (6-ohda)-induced lesions of da terminals within the core and medial shell subregions of the nucleus accumbens (nac) would enhance li under conditions that normally disrupt li in controls (weak pre-exposure). |
2011-05-04 |
2023-08-12 |
Not clear |
| Flavie Kersanté, Jin-Ya Wang, Jin-Chung Chen, Catherine Mollereau, Jean-Marie Zaja. Anti-opioid effects of neuropeptide FF receptors in the ventral tegmental area. Neuroscience letters. vol 488. issue 3. 2011-05-02. PMID:21111027. |
a stable npff(2) receptor agonist, dnpa, was injected into the ventral tegmental area (vta) and the release of dopamine and serotonin within the nucleus accumbens (nac), induced by intraperitoneal injection of morphine, was monitored using the brain microdialysis, in non-constrained rat. |
2011-05-02 |
2023-08-12 |
rat |
| S L Sánchez-Serrano, S L Cruz, M Lama. Repeated toluene exposure modifies the acetylation pattern of histones H3 and H4 in the rat brain. Neuroscience letters. vol 489. issue 3. 2011-04-29. PMID:21146589. |
in order to decipher whether repeated toluene exposure could mediate epigenetic changes in the rat brain, we here analyzed the acetylation pattern of histones h3 and h4 in three brain areas that have been previously associated to substance abuse reward pathways: the nucleus accumbens (nac), the ventral tegmental area (vta) and the central amygdala (cea). |
2011-04-29 |
2023-08-12 |
rat |
| Ping Mu, Peter A Neumann, Jaak Panksepp, Oliver M Schlüter, Yan Don. Exposure to cocaine alters dynorphin-mediated regulation of excitatory synaptic transmission in nucleus accumbens neurons. Biological psychiatry. vol 69. issue 3. 2011-04-28. PMID:21030009. |
dysregulation of excitatory synaptic input to nucleus accumbens (nac) medium spiny neurons (msns) underlies a key pathophysiology of drug addiction and addiction-associated emotional and motivational alterations. |
2011-04-28 |
2023-08-12 |
Not clear |
| Alison K Berger, Thomas Green, Steven J Siegel, Eric J Nestler, Ronald P Hamme. cAMP response element binding protein phosphorylation in nucleus accumbens underlies sustained recovery of sensorimotor gating following repeated D₂-like receptor agonist treatment in rats. Biological psychiatry. vol 69. issue 3. 2011-04-28. PMID:21035786. |
repeated treatment with a d₂-like agonist, however, reverses ppi deficits and increases cyclic adenosine monophosphate (camp) signaling in the nucleus accumbens (nac). |
2011-04-28 |
2023-08-12 |
rat |
| Elvar M Eyjolfsson, Linn Hege Nilsen, Daniel Kondziella, Eiliv Brenner, Asta Håberg, Ursula Sonnewal. Altered 13C glucose metabolism in the cortico-striato-thalamo-cortical loop in the MK-801 rat model of schizophrenia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 31. issue 3. 2011-04-27. PMID:21081956. |
extracts of frontal cortex (fcx), parietal and temporal cortex (ptcx), thalamus, striatum, nucleus accumbens (nac), and hippocampus were analyzed using (13)c nuclear magnetic resonance spectroscopy, high-performance liquid chromatography, and gas chromatography-mass spectrometry. |
2011-04-27 |
2023-08-12 |
rat |
| Atsumi Nitta, Yoko Hibi, Yoshiaki Miyamoto, Toshitaka Nabeshim. [Identification of Piccolo as a regulator of behavioral plasticity and dopamine transporter internalization]. Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence. vol 45. issue 6. 2011-04-26. PMID:21387608. |
we found that piccolo, a presynaptic scaffolding protein, was overexpressed in the nucleus accumbens (nac) of the mice repeatedly administrated with meth. |
2011-04-26 |
2023-08-12 |
mouse |
| Louise Adermark, Rhona B C Clarke, Torsten Olsson, Elisabeth Hansson, Bo Söderpalm, Mia Ericso. Implications for glycine receptors and astrocytes in ethanol-induced elevation of dopamine levels in the nucleus accumbens. Addiction biology. vol 16. issue 1. 2011-04-25. PMID:20331561. |
elevated dopamine levels are believed to contribute to the rewarding sensation of ethanol (etoh), and previous research has shown that strychnine-sensitive glycine receptors in the nucleus accumbens (nac) are involved in regulating dopamine release and in mediating the reinforcing effects of etoh. |
2011-04-25 |
2023-08-12 |
rat |
| Hui Yu, Zhe-yu Che. The role of BDNF in depression on the basis of its location in the neural circuitry. Acta pharmacologica Sinica. vol 32. issue 1. 2011-04-25. PMID:21131999. |
here, we present an overview of the current knowledge concerning bdnf actions and associated intracellular signaling in hippocampus, prefrontal cortex, nucleus accumbens (nac) and amygdala as their relation to depression. |
2011-04-25 |
2023-08-12 |
Not clear |
| M Beyene, R M Carelli, R M Wightma. Cue-evoked dopamine release in the nucleus accumbens shell tracks reinforcer magnitude during intracranial self-stimulation. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600644. |
it has previously been shown, using fast-scan cyclic voltammetry in behaving rats, that cues predicting a variety of reinforcers including food/water, cocaine or intracranial self-stimulation (icss) elicit time-locked transient fluctuations in dopamine concentration in the nucleus accumbens (nac) shell. |
2011-04-18 |
2023-08-12 |
rat |
| E C Muly, M Maddox, Z U Kha. Distribution of D1 and D5 dopamine receptors in the primate nucleus accumbens. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600664. |
the d1 family of dopamine receptors (d1r) play a critical role in modulating reward in the nucleus accumbens (nac). |
2011-04-18 |
2023-08-12 |
Not clear |
| Ian Maze, Jian Feng, Matthew B Wilkinson, HaoSheng Sun, Li Shen, Eric J Nestle. Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 7. 2011-04-14. PMID:21300862. |
here, we report that cocaine dramatically and dynamically alters heterochromatic histone h3 lysine 9 trimethylation (h3k9me3) in the nucleus accumbens (nac), a key brain reward region. |
2011-04-14 |
2023-08-12 |
Not clear |
| Nanna Hovelsø, Thomas Nicolaj Sager, Arne Mør. Combination of escitalopram and a 5-HT(₁A) receptor antagonist selectively decreases the extracellular levels of dopamine in the nucleus accumbens relative to striatum through 5-HT(₂C) receptor stimulation; suggestive of antipsychotic potential. Pharmacology, biochemistry, and behavior. vol 97. issue 3. 2011-04-11. PMID:20937301. |
the combined treatment was found to decrease both car behaviour without affecting escape failures and the basal extracellular levels of dopamine (da) in the nucleus accumbens (nac) acutely without affecting da levels in the striatum, suggesting an antipsychotic-like effect with mesolimbic selectivity. |
2011-04-11 |
2023-08-12 |
rat |
| Christian Lüscher, Robert C Malenk. Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling. Neuron. vol 69. issue 4. 2011-04-08. PMID:21338877. |
this system originates in the ventral tegmental area (vta) and projects mainly to the nucleus accumbens (nac) and prefrontal cortex (pfc). |
2011-04-08 |
2023-08-12 |
Not clear |
| Charlotte Wiker, Love Linnér, Marie-Louise Wadenberg, Torgny H Svensso. Adjunctive treatment with mianserin enhances effects of raclopride on cortical dopamine output and, in parallel, its antipsychotic-like effect. Neuropsychiatric disease and treatment. vol 1. issue 4. 2011-04-06. PMID:18568117. |
here, we have examined the effect of mianserin in combination with the selective dopamine (da) d(2/3) receptor antagonist raclopride on conditioned avoidance response (car), a preclinical test of antipsychotic efficacy with high predictive validity; catalepsy, a preclinical test of extrapyramidal side effect liability; and da output in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), respectively. |
2011-04-06 |
2023-08-12 |
rat |