| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rutsuko Ito, Anja Haye. Opposing roles of nucleus accumbens core and shell dopamine in the modulation of limbic information processing. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 16. 2011-06-30. PMID:21508225. |
the dopaminergic innervation of the nucleus accumbens (nac) is implicated in the selection and integration of motivationally relevant corticolimbic information that governs behavioral output. |
2011-06-30 |
2023-08-12 |
mouse |
| Viviana Trezza, Ruth Damsteegt, E J Marijke Achterberg, Louk J M J Vanderschure. Nucleus accumbens μ-opioid receptors mediate social reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 17. 2011-06-24. PMID:21525276. |
here, we studied the neural underpinnings of social reward by investigating the involvement of opioid neurotransmission in the nucleus accumbens (nac) in social play behavior, a highly rewarding social interaction in adolescent rats. |
2011-06-24 |
2023-08-12 |
rat |
| Xiao-Qing Peng, Eliot L Gardner, Zheng-Xiong X. Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters. Psychopharmacology. vol 208. issue 4. 2011-06-21. PMID:20033132. |
we have recently reported that gamma-vinyl gaba (gvg), an irreversible gaba transaminase inhibitor, elevates extracellular gaba but fails to alter dopamine release in the nucleus accumbens (nac). |
2011-06-21 |
2023-08-12 |
rat |
| Colin M Stopper, Stan B Floresc. Contributions of the nucleus accumbens and its subregions to different aspects of risk-based decision making. Cognitive, affective & behavioral neuroscience. vol 11. issue 1. 2011-06-21. PMID:21264647. |
the nucleus accumbens (nac) has been implicated in mediating different forms of decision making in humans and animals. |
2011-06-21 |
2023-08-12 |
rat |
| Patricia Miner, Yaffa Borkuhova, Lyudmila Shimonova, Arthur Khaimov, Richard J Bodna. GABA-A and GABA-B receptors mediate feeding elicited by the GABA-B agonist baclofen in the ventral tegmental area and nucleus accumbens shell in rats: reciprocal and regional interactions. Brain research. vol 1355. 2011-06-20. PMID:20696149. |
food intake is significantly increased following administration of gaba-b and gaba-a agonists into the nucleus accumbens (nac) shell and ventral tegmental area (vta) with receptor-selective antagonist pretreatment capable of blocking these responses within sites. |
2011-06-20 |
2023-08-12 |
rat |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Alice Y W Chang, Julie Y H Chan, Samuel H H Chan, Kuei-Sen Hs. Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411660. |
neuroadaptation in the nucleus accumbens (nac), a central component of the mesolimbic dopamine (da) system, has been implicated in the development of cocaine-induced psychomotor sensitization and relapse to cocaine seeking. |
2011-06-15 |
2023-08-12 |
mouse |
| Kathryn J Reissner, Joachim D Uys, John H Schwacke, Susanna Comte-Walters, Jennifer L Rutherford-Bethard, Thomas E Dunn, Joe B Blumer, Kevin L Schey, Peter W Kaliva. AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490206. |
to identify candidate proteins in the nucleus accumbens (nac) as potential pharmacotherapeutic targets for treating cocaine addition, an 8-plex itraq (isobaric tag for relative and absolute quantitation) proteomic screen was performed using nac tissue obtained from rats trained to self-administer cocaine followed by extinction training. |
2011-06-13 |
2023-08-12 |
human |
| James E McCutcheon, Xiaoting Wang, Kuei Y Tseng, Marina E Wolf, Michela Marinell. Calcium-permeable AMPA receptors are present in nucleus accumbens synapses after prolonged withdrawal from cocaine self-administration but not experimenter-administered cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490215. |
repeated noncontingent cocaine injections, which lead to behavioral sensitization, increase ampa receptor (ampar) transmission in the rodent nucleus accumbens (nac) in a withdrawal-dependent manner. |
2011-06-13 |
2023-08-12 |
mouse |
| Carrie R Ferrario, Jessica A Loweth, Mike Milovanovic, Xiaoting Wang, Marina E Wol. Distribution of AMPA receptor subunits and TARPs in synaptic and extrasynaptic membranes of the adult rat nucleus accumbens. Neuroscience letters. vol 490. issue 3. 2011-06-01. PMID:21182898. |
we characterized the distribution of ampa receptor (ampar) subunits and the transmembrane ampa receptor regulatory proteins (tarps) γ-2 and γ-4 in adult rat nucleus accumbens (nac) using a method that separates plasma membranes into synaptic membrane-enriched and extrasynaptic membrane-enriched fractions. |
2011-06-01 |
2023-08-12 |
rat |
| L Naef, L Moquin, G Dal Bo, B Giros, A Gratton, C-D Walke. Maternal high-fat intake alters presynaptic regulation of dopamine in the nucleus accumbens and increases motivation for fat rewards in the offspring. Neuroscience. vol 176. 2011-06-01. PMID:21187125. |
here, we report that the subsensitivity of high-fat offspring to amp's locomotor stimulant action reflects, at least in part, altered regulation of nucleus accumbens (nac) dopamine (da) transmission. |
2011-06-01 |
2023-08-12 |
Not clear |
| L Pozzi, M Baviera, G Sacchetti, E Calcagno, C Balducci, R W Invernizzi, M Carl. Attention deficit induced by blockade of N-methyl D-aspartate receptors in the prefrontal cortex is associated with enhanced glutamate release and cAMP response element binding protein phosphorylation: role of metabotropic glutamate receptors 2/3. Neuroscience. vol 176. 2011-06-01. PMID:21193020. |
in parallel studies using microdialysis technique and western blot analysis we found that (r)-cpp (100 μm) infused in the medial prefrontal cortex increased glutamate efflux whereas injected in the medial prefrontal cortex at a dose causing impairments in attentional performance (50 ng/side) increased p-s(133)creb in the frontal cortex (fc), decreased it in the caudate-putamen (cpu) and was without effect in the nucleus accumbens (nac). |
2011-06-01 |
2023-08-12 |
rat |
| Jeremy J Day, Joshua L Jones, Regina M Carell. Nucleus accumbens neurons encode predicted and ongoing reward costs in rats. The European journal of neuroscience. vol 33. issue 2. 2011-06-01. PMID:21198983. |
the nucleus accumbens (nac) has been implicated in the ability to choose between options with different costs and overcome high costs when necessary, but it is not clear how nac processing contributes to this role. |
2011-06-01 |
2023-08-12 |
rat |
| Jocelyn M Richard, Kent C Berridg. Metabotropic glutamate receptor blockade in nucleus accumbens shell shifts affective valence towards fear and disgust. The European journal of neuroscience. vol 33. issue 4. 2011-05-31. PMID:21198990. |
glutamatergic inputs to the nucleus accumbens (nac) modulate both appetitive and fearful motivation. |
2011-05-31 |
2023-08-12 |
rat |
| Lisa R Beutler, Matthew J Wanat, Albert Quintana, Elisenda Sanz, Nigel S Bamford, Larry S Zweifel, Richard D Palmite. Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 10. 2011-05-26. PMID:21368124. |
conversely, removing nmdars from msns that express the dopamine d1 receptor (d1r) significantly attenuated amph sensitization, and conditional, virus-mediated restoration of nr1 in d1r neurons in the nucleus accumbens (nac) of these animals rescued sensitization. |
2011-05-26 |
2023-08-12 |
Not clear |
| Xueqin Zhang, Yue Cui, Jin Jing, Yu Cui, Wenjun Xin, Xianguo Li. Involvement of p38/NF-κB signaling pathway in the nucleus accumbens in the rewarding effects of morphine in rats. Behavioural brain research. vol 218. issue 1. 2011-05-25. PMID:21130118. |
the nucleus accumbens (nac) is one of the important brain regions for the acquisition of morphine-induced conditioned place preference (cpp), which is a valuable paradigm for detecting the rewarding effects of drugs. |
2011-05-25 |
2023-08-12 |
rat |
| Yi-ming Wei, Su-xia Li, Hai-shui Shi, Zeng-bo Ding, Yi-xiao Luo, Yan-xue Xue, Lin Lu, Chang-xi Y. Protracted cocaine withdrawal produces circadian rhythmic alterations of phosphorylated GSK-3β in reward-related brain areas in rats. Behavioural brain research. vol 218. issue 1. 2011-05-25. PMID:21130813. |
blunted circadian rhythms of phosphorylated gfk-3β (pgsk-3β) persisted for at least 30 days in all examined brain areas, with the exception of 10 days in the suprachiasmatic nucleus (scn) and nucleus accumbens (nac). |
2011-05-25 |
2023-08-12 |
rat |
| Juan Luo, Li Jing, Wang-Jun Qin, Min Zhang, Andrew J Lawrence, Feng Chen, Jian-Hui Lian. Transcription and protein synthesis inhibitors reduce the induction of behavioural sensitization to a single morphine exposure and regulate Hsp70 expression in the mouse nucleus accumbens. The international journal of neuropsychopharmacology. vol 14. issue 1. 2011-05-24. PMID:20519062. |
in combination with behavioural experiments, changes in gene and protein expression in the mouse nucleus accumbens (nac) were analysed by rt-pcr array and western blot respectively. |
2011-05-24 |
2023-08-12 |
mouse |
| A J D Nelson, K E Thur, C A Marsden, H J Cassada. Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition. Neuroscience. vol 170. issue 1. 2011-05-24. PMID:20619321. |
investigations into the neural substrates of li have focused on the nucleus accumbens (nac) and its inputs from the hippocampal formation and adjacent cortical areas. |
2011-05-24 |
2023-08-12 |
Not clear |
| Mercè Masana, Analía Bortolozzi, Francesc Artiga. Selective enhancement of mesocortical dopaminergic transmission by noradrenergic drugs: therapeutic opportunities in schizophrenia. The international journal of neuropsychopharmacology. vol 14. issue 1. 2011-05-24. PMID:20701825. |
given that noradrenergic (ne) transmission contributes to cortical da output, we assessed the ability of ne-targeting drugs to modulate da release in medial prefrontal cortex (mpfc) and nucleus accumbens (nac), with the aim of selectively increasing mesocortical da. |
2011-05-24 |
2023-08-12 |
rat |
| H M Francis, N J Kraushaar, L R Hunt, J L Cornis. Serotonin 5-HT4 receptors in the nucleus accumbens are specifically involved in the appetite suppressant and not locomotor stimulant effects of MDMA ('ecstasy'). Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:20740276. |
the nucleus accumbens (nac) is a brain region associated with the regulation of motivated and locomotor behaviours, and recent evidence suggests that nac 5-ht4 receptors are likely to be involved in the appetite suppressant effect of mdma. |
2011-05-24 |
2023-08-12 |
Not clear |