| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zivjena Vucetic, Jessica Kimmel, Teresa M Reye. Chronic high-fat diet drives postnatal epigenetic regulation of μ-opioid receptor in the brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 6. 2012-02-09. PMID:21326195. |
mor mrna expression was decreased in reward-related circuitry (ventral tegmental area (vta), nucleus accumbens (nac), and prefrontal cortex (pfc)) but not the hypothalamus, important in the homeostatic regulation of feeding. |
2012-02-09 |
2023-08-12 |
mouse |
| Jen-Hsin Kao, Eagle Yi-Kung Huang, Pao-Luh Ta. NR2B subunit of NMDA receptor at nucleus accumbens is involved in morphine rewarding effect by siRNA study. Drug and alcohol dependence. vol 118. issue 2-3. 2012-02-09. PMID:21601998. |
it is also well recognized that the nucleus accumbens (nac) and the ventral tegmental area (vta) are involved in drug addiction, including morphine addiction. |
2012-02-09 |
2023-08-12 |
Not clear |
| Amine Bahi, Jean-Luc Dreye. Involvement of tissue plasminogen activator "tPA" in ethanol-induced locomotor sensitization and conditioned-place preference. Behavioural brain research. vol 226. issue 1. 2012-02-09. PMID:21945298. |
ethanol treatment dose-dependently induced tpa enzymatic activity in the nucleus accumbens (nac). |
2012-02-09 |
2023-08-12 |
mouse |
| David N Potter, Diane Damez-Werno, William A Carlezon, Bruce M Cohen, Elena H Chartof. Repeated exposure to the κ-opioid receptor agonist salvinorin A modulates extracellular signal-regulated kinase and reward sensitivity. Biological psychiatry. vol 70. issue 8. 2012-01-31. PMID:21757186. |
repeated exposure to drugs of abuse and stress increase dynorphin, a κ opioid receptor (kor) ligand, in the nucleus accumbens (nac). |
2012-01-31 |
2023-08-12 |
Not clear |
| Brian R Lee, Yan Don. Cocaine-induced metaplasticity in the nucleus accumbens: silent synapse and beyond. Neuropharmacology. vol 61. issue 7. 2012-01-27. PMID:21232547. |
we recently demonstrated that repeated exposure to cocaine generated a large portion of "silent" glutamatergic synapses within the nucleus accumbens (nac). |
2012-01-27 |
2023-08-12 |
Not clear |
| Carrie R Ferrario, Jessica A Loweth, Mike Milovanovic, Kerstin A Ford, Gregorio L Galiñanes, Li-Jun Heng, Kuei Y Tseng, Marina E Wol. Alterations in AMPA receptor subunits and TARPs in the rat nucleus accumbens related to the formation of Ca²⁺-permeable AMPA receptors during the incubation of cocaine craving. Neuropharmacology. vol 61. issue 7. 2012-01-27. PMID:21276808. |
the expression of incubated craving is mediated by ca²⁺-permeable ampa receptors (cp-ampars) in the nucleus accumbens (nac). |
2012-01-27 |
2023-08-12 |
rat |
| Patrick E Rothwell, Saïd Kourrich, Mark J Thoma. Environmental novelty causes stress-like adaptations at nucleus accumbens synapses: implications for studying addiction-related plasticity. Neuropharmacology. vol 61. issue 7. 2012-01-27. PMID:21315090. |
here, we show that exposure to a novel environment produces functional synaptic adaptations in the nucleus accumbens (nac) that mirror the effect of conventional forms of stress. |
2012-01-27 |
2023-08-12 |
mouse |
| Klaus A Miczek, Ella M Nikulina, Aki Takahashi, Herbert E Covington, Jasmine J Yap, Christopher O Boyson, Akiko Shimamoto, Rosa M M de Almeid. Gene expression in aminergic and peptidergic cells during aggression and defeat: relevance to violence, depression and drug abuse. Behavior genetics. vol 41. issue 6. 2012-01-23. PMID:21416141. |
brief episodes of social defeat stress induce an augmented response to stimulant challenge as reflected by increased locomotion and increased extracellular dopamine (da) in the nucleus accumbens (nac). |
2012-01-23 |
2023-08-12 |
mouse |
| Xiao Han, Weiwen Wang, Xiaofang Xue, Feng Shao, Nanxin L. Brief social isolation in early adolescence affects reversal learning and forebrain BDNF expression in adult rats. Brain research bulletin. vol 86. issue 3-4. 2012-01-23. PMID:21801814. |
we also found that brain-derived neurotrophic factor (bdnf) protein expression was increased in the medial prefrontal cortex (mpfc) but was decreased in the nucleus accumbens (nac), ca1 and dentate gyrus of the hippocampus in isolation-reared rats. |
2012-01-23 |
2023-08-12 |
rat |
| Frédéric Lallemand, Roberta J Ward, Philippe De Witte, Paul Verbanc. Binge drinking +/- chronic nicotine administration alters extracellular glutamate and arginine levels in the nucleus accumbens of adult male and female Wistar rats. Alcohol and alcoholism (Oxford, Oxfordshire). vol 46. issue 4. 2012-01-20. PMID:21478495. |
the effect of 'binge drinking' coupled or not with chronic nicotine administration on nucleus accumbens (nac) glutamate, arginine, taurine and hydroxyl radical levels has been investigated in these present studies. |
2012-01-20 |
2023-08-12 |
rat |
| T Inui, C Inui-Yamamoto, Y Yoshioka, I Ohzawa, T Shimur. Activation of projective neurons from the nucleus accumbens to ventral pallidum by a learned aversive taste stimulus in rats: a manganese-enhanced magnetic resonance imaging study. Neuroscience. vol 177. 2012-01-19. PMID:21219975. |
because the vp receives major projections from the nucleus accumbens (nac), we examined whether the presentation of cs activates the nac-vp projective neurons after the establishment of cta, using a manganese-enhanced magnetic resonance imaging technique. |
2012-01-19 |
2023-08-12 |
rat |
| Maria Hadjiconstantinou, Norton H Nef. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:21108953. |
1) the synthesis and release of β-endorphin, met-enkephalin and dynorphin in brain, especially nucleus accumbens (nac), are altered after acute or chronic nicotine treatment and during nicotine withdrawal. |
2012-01-18 |
2023-08-12 |
Not clear |
| David N George, Trisha A Jenkins, Simon Killcros. Dissociation of prefrontal cortex and nucleus accumbens dopaminergic systems in conditional learning in rats. Behavioural brain research. vol 225. issue 1. 2012-01-18. PMID:21741412. |
following training, microdialysis probes were implanted unilaterally in either the medial prefrontal cortex (mpfc) or nucleus accumbens (nac) and samples were collected in freely moving animals during a behavioural test session. |
2012-01-18 |
2023-08-12 |
rat |
| Elisabet Salas, Carlos Bocos, Carmen Del Castillo, Carmen Pérez-García, Lidia Morales, Luis F Alguaci. Gene expression analysis of heat shock proteins in the nucleus accumbens of rats with different morphine seeking behaviours. Behavioural brain research. vol 225. issue 1. 2012-01-18. PMID:21763353. |
this work tries to provide new knowledge on this field by using two rat models of differential vulnerability to morphine addiction in order to study differential gene expression of a selected group of hsp genes in the nucleus accumbens (nac). |
2012-01-18 |
2023-08-12 |
rat |
| T Seif, A Makriyannis, G Kunos, A Bonci, F W Hop. The endocannabinoid 2-arachidonoylglycerol mediates D1 and D2 receptor cooperative enhancement of rat nucleus accumbens core neuron firing. Neuroscience. vol 193. 2012-01-18. PMID:21821098. |
many motivated and addiction-related behaviors are sustained by activity of both dopamine d1- and d2-type receptors (d1rs and d2rs) as well as cb1 receptors (cb1rs) in the nucleus accumbens (nac). |
2012-01-18 |
2023-08-12 |
rat |
| Caroline M Hostetler, Alex S Kowalczyk, Luana L Griffin, Karen L Bale. CART peptide following social novelty in the prairie vole (Microtus ochrogaster). Brain research. vol 1414. 2012-01-18. PMID:21871610. |
additionally, cart peptide was higher in the nucleus accumbens (nac) of subjects paired with an opposite sex partner compared to those paired with a same-sex conspecific, although there was no difference between isolated subjects and either socially housed group. |
2012-01-18 |
2023-08-12 |
human |
| Gary B Kaplan, Kimberly A Leite-Morris, WenYing Fan, Angela J Young, Marsha D Gu. Opiate sensitization induces FosB/ΔFosB expression in prefrontal cortical, striatal and amygdala brain regions. PloS one. vol 6. issue 8. 2012-01-17. PMID:21886798. |
intermittent morphine pre-treatment on these six pre-treatment days produced a significant induction of fosb/Δfosb, measured on day 16, in multiple brain regions including prelimbic (pl) and infralimbic (il) cortex, nucleus accumbens (nac) core, dorsomedial caudate-putamen (cpu), basolateral amygdala (bla) and central nucleus of the amygdala (cna) but not in a motor cortex control region. |
2012-01-17 |
2023-08-12 |
mouse |
| Melissa Malvaez, Emanuela Mhillaj, Dina P Matheos, Maura Palmery, Marcelo A Woo. CBP in the nucleus accumbens regulates cocaine-induced histone acetylation and is critical for cocaine-associated behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 47. 2012-01-16. PMID:22114264. |
we examined the role of cbp in drug-induced plasticity using cbp-flox genetically modified mice in combination with adeno-associated virus expressing cre-recombinase to generate focal homozygous deletions of cbp in the nucleus accumbens (nac). |
2012-01-16 |
2023-08-12 |
mouse |
| Jérémie Neasta, Sami Ben Hamida, Quinn V Yowell, Sebastien Carnicella, Dorit Ro. AKT signaling pathway in the nucleus accumbens mediates excessive alcohol drinking behaviors. Biological psychiatry. vol 70. issue 6. 2012-01-09. PMID:21549353. |
neuroadaptations within the nucleus accumbens (nac) have been implicated in molecular mechanisms underlying the development and/or maintenance of alcohol abuse disorders. |
2012-01-09 |
2023-08-12 |
Not clear |
| Jinwoo Park, Pavel Takmakov, R Mark Wightma. In vivo comparison of norepinephrine and dopamine release in rat brain by simultaneous measurements with fast-scan cyclic voltammetry. Journal of neurochemistry. vol 119. issue 5. 2012-01-09. PMID:21933188. |
in this study, we demonstrate differences in the regulation of in vivo neurotransmission for dopamine in the anterior nucleus accumbens (nac) and norepinephrine in the ventral bed nucleus of the stria terminalis (vbnst) of the anesthetized rat. |
2012-01-09 |
2023-08-12 |
rat |