| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Clara Velazquez-Sanchez, Antonio Ferragud, Jaime Renau-Piqueras, Juan J Canale. Therapeutic-like properties of a dopamine uptake inhibitor in animal models of amphetamine addiction. The international journal of neuropsychopharmacology. vol 14. issue 5. 2012-01-06. PMID:20735880. |
we tested in mice and rats the effects of the bzt derivative, 3α-[bis(4-fluorophenyl)methoxy]-tropane (ahn-1055), on amph-induced conditioned place preference (cpp), locomotor activity, sensitization, self-administration and Δfosb accumulation in the nucleus accumbens (nac). |
2012-01-06 |
2023-08-12 |
mouse |
| Xuan Li, Marina E Wol. Brain-derived neurotrophic factor rapidly increases AMPA receptor surface expression in rat nucleus accumbens. The European journal of neuroscience. vol 34. issue 2. 2012-01-05. PMID:21692887. |
in the rodent nucleus accumbens (nac), cocaine elevates levels of brain-derived neurotrophic factor (bdnf). |
2012-01-05 |
2023-08-12 |
rat |
| Erin B Larson, Danielle L Graham, Rose R Arzaga, Nicole Buzin, Joseph Webb, Thomas A Green, Caroline E Bass, Rachael L Neve, Ernest F Terwilliger, Eric J Nestler, David W Sel. Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 45. 2012-01-04. PMID:22072694. |
chronic exposure to addictive drugs enhances camp response element binding protein (creb)-regulated gene expression in nucleus accumbens (nac), and these effects are thought to reduce the positive hedonic effects of passive cocaine administration. |
2012-01-04 |
2023-08-12 |
rat |
| Suelen Lucio Boschen, Evellyn Claudia Wietzikoski, Philip Winn, Claudio Da Cunh. The role of nucleus accumbens and dorsolateral striatal D2 receptors in active avoidance conditioning. Neurobiology of learning and memory. vol 96. issue 2. 2011-12-27. PMID:21619938. |
here we tested the role of d2-like da receptors in the nucleus accumbens (nac) and the dorsolateral striatum (dls) of rats in the learning and performance of conditioned avoidance responses (car). |
2011-12-27 |
2023-08-12 |
rat |
| Amy R Furay, Ross A McDevitt, Klaus A Miczek, John F Neumaie. 5-HT1B mRNA expression after chronic social stress. Behavioural brain research. vol 224. issue 2. 2011-12-21. PMID:21718722. |
the 5-ht(1b) receptor is expressed in nucleus accumbens (nac) projection neurons and modulates drug reward mechanisms and there is evidence suggesting that stress alters the regulation and function of these receptors. |
2011-12-21 |
2023-08-12 |
rat |
| Adriana A Alcantara, Helen Y Lim, Christopher E Floyd, Juanita Garces, John M Mendenhall, Chelsea L Lyons, Monica L Berlang. Cocaine- and morphine-induced synaptic plasticity in the nucleus accumbens. Synapse (New York, N.Y.). vol 65. issue 4. 2011-12-20. PMID:20730804. |
this study examined behavioral changes and electron microscopic evidence of altered synaptic connectivity within the nucleus accumbens (nac) following repeated administration of cocaine or morphine. |
2011-12-20 |
2023-08-12 |
rat |
| Thomas F Tropea, Zeeba D Kabir, Gagandeep Kaur, Anjali M Rajadhyaksha, Barry E Kosofsk. Enhanced dopamine D1 and BDNF signaling in the adult dorsal striatum but not nucleus accumbens of prenatal cocaine treated mice. Frontiers in psychiatry. vol 2. 2011-12-15. PMID:22162970. |
in this study we further examined basal as well as cocaine or d1-induced activation of a set of molecules known to be mediators of neuronal plasticity following psychostimulant treatment, with emphasis in the dorsal striatum (str) and nucleus accumbens (nac) of adult mice exposed to cocaine in utero. |
2011-12-15 |
2023-08-12 |
mouse |
| Ronak Azizbeigi, Shamseddin Ahmadi, Vahab Babapour, Ameneh Rezayof, Mohammad Reza Zarrindas. Nicotine restores morphine-induced memory deficit through the D1 and D2 dopamine receptor mechanisms in the nucleus accumbens. Journal of psychopharmacology (Oxford, England). vol 25. issue 8. 2011-12-13. PMID:21616978. |
involvement of the dopamine d1 and d2 receptors in the nucleus accumbens (nac) with interaction between morphine and nicotine on inhibitory avoidance (ia) memory was investigated. |
2011-12-13 |
2023-08-12 |
rat |
| Moonnoh R Lee, David J Hinton, Jinhua Wu, Prasanna K Mishra, John D Port, Slobodan I Macura, Doo-Sup Cho. Acamprosate reduces ethanol drinking behaviors and alters the metabolite profile in mice lacking ENT1. Neuroscience letters. vol 490. issue 2. 2011-12-12. PMID:21172405. |
since elevated glutamate signaling, especially in the nucleus accumbens (nac), is implicated in several aspects of alcoholism, we utilized mice lacking type 1 equilibrative nucleoside transporter (ent1), which exhibit increased glutamate levels in the nac as well as increased ethanol drinking behaviors. |
2011-12-12 |
2023-08-12 |
mouse |
| Moonnoh R Lee, David J Hinton, Jinhua Wu, Prasanna K Mishra, John D Port, Slobodan I Macura, Doo-Sup Cho. Acamprosate reduces ethanol drinking behaviors and alters the metabolite profile in mice lacking ENT1. Neuroscience letters. vol 490. issue 2. 2011-12-12. PMID:21172405. |
our data show that basal glutamate+glutamine (glx), glutamate, glutamine and n-acetylaspartatic acid (naa) levels are increased in the nucleus accumbens (nac) of ent1(-/-) compared to wild-type mice. |
2011-12-12 |
2023-08-12 |
mouse |
| Alicia J Saylor, Jacqueline F McGint. An intrastriatal brain-derived neurotrophic factor infusion restores striatal gene expression in Bdnf heterozygous mice. Brain structure & function. vol 215. issue 2. 2011-12-09. PMID:20938680. |
mice were killed 24 h later and semi-quantitative in situ hybridization histochemical analysis confirmed that ppd, ppe, and d(3) receptor mrna was less in the caudate-putamen (cpu) and nucleus accumbens (nac) core of bdnf (+/-) mice than in wildtype mice. |
2011-12-09 |
2023-08-12 |
mouse |
| Kathryn Schierberl, Jin Hao, Thomas F Tropea, Stephen Ra, Thomas P Giordano, Qinghao Xu, Sandra M Garraway, Franz Hofmann, Sven Moosmang, Joerg Striessnig, Charles E Inturrisi, Anjali M Rajadhyaksh. Cav1.2 L-type Ca²⁺ channels mediate cocaine-induced GluA1 trafficking in the nucleus accumbens, a long-term adaptation dependent on ventral tegmental area Ca(v)1.3 channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 38. 2011-12-07. PMID:21940447. |
utilizing cocaine psychomotor sensitization, we have examined phosphorylation of glua1 at key residues serine 845 (s845) and s831, as well as glua1 cell surface levels in the nucleus accumbens (nac) of cocaine-preexposed mice and the role of brain-specific ca(v)1.2 and ca(v)1.3 l-type ca²⁺ channels (ltccs), therein. |
2011-12-07 |
2023-08-12 |
mouse |
| Amanda M Dossat, Nicole Lilly, Kristen Kay, Diana L William. Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 41. 2011-12-06. PMID:21994361. |
one such region is the nucleus accumbens (nac), which plays a role in reward and motivated behavior. |
2011-12-06 |
2023-08-12 |
rat |
| James E McCutcheon, Jessica A Loweth, Kerstin A Ford, Michela Marinelli, Marina E Wolf, Kuei Y Tsen. Group I mGluR activation reverses cocaine-induced accumulation of calcium-permeable AMPA receptors in nucleus accumbens synapses via a protein kinase C-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 41. 2011-12-06. PMID:21994370. |
following prolonged withdrawal from extended access cocaine self-administration in adult rats, high conductance ca2+ -ermeable ampa receptors (cp-ampars) accumulate in nucleus accumbens (nac) synapses and mediate the expression of "incubated" cue-induced cocaine craving. |
2011-12-06 |
2023-08-12 |
rat |
| Mia Ericson, PeiPei Chau, Rhona B Clarke, Louise Adermark, Bo Söderpal. Rising taurine and ethanol concentrations in nucleus accumbens interact to produce dopamine release after ethanol administration. Addiction biology. vol 16. issue 3. 2011-12-02. PMID:21156034. |
we have previously demonstrated that glycine receptors in the nucleus accumbens (nac) are involved in modulating both basal and ethanol-induced dopamine output in the same brain region. |
2011-12-02 |
2023-08-12 |
rat |
| Neal R Swerdlow, Michelle R Breier, Richard L Saint Mari. Probing the molecular basis for an inherited sensitivity to the startle-gating disruptive effects of apomorphine in rats. Psychopharmacology. vol 216. issue 3. 2011-11-29. PMID:21365203. |
in rats, the dopamine agonist, apomorphine (apo), reduces ppi and expression of the early gene, c-fos, within the nucleus accumbens (nac) core. |
2011-11-29 |
2023-08-12 |
rat |
| Jay Hosking, Catharine A Winstanle. Impulsivity as a mediating mechanism between early-life adversity and addiction: theoretical comment on Lovic et al. (2011). Behavioral neuroscience. vol 125. issue 4. 2011-11-29. PMID:21787043. |
recent literature suggests that these results are likely due to structural and functional changes in regions such as the orbitofrontal cortex (ofc) and nucleus accumbens (nac), as well as altered dopamine activity. |
2011-11-29 |
2023-08-12 |
Not clear |
| D Quarta, C P Leslie, R Carletti, E Valerio, L Caberlott. Central administration of NPY or an NPY-Y5 selective agonist increase in vivo extracellular monoamine levels in mesocorticolimbic projecting areas. Neuropharmacology. vol 60. issue 2-3. 2011-11-22. PMID:20868698. |
thus, the first aim of the present study was to investigate the distribution of npy-y5 receptor binding sites in rat mesocorticolimbic projection areas such as the nucleus accumbens (nac), medial prefrontal cortex (mpfc), and lateral hypothalamus (lh). |
2011-11-22 |
2023-08-12 |
rat |
| Lindsey P Pattison, Keith D Bonin, Scott E Hemby, Evgeny A Budygi. Speedball induced changes in electrically stimulated dopamine overflow in rat nucleus accumbens. Neuropharmacology. vol 60. issue 2-3. 2011-11-22. PMID:20869972. |
cocaine/heroin combinations (speedball) induce a synergistic elevation in extracellular dopamine concentrations ([da](e)) in the nucleus accumbens (nac) that can explain the increased abuse liability of speedball. |
2011-11-22 |
2023-08-12 |
rat |
| Fabio Cacciapaglia, R Mark Wightman, Regina M Carell. Rapid dopamine signaling differentially modulates distinct microcircuits within the nucleus accumbens during sucrose-directed behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 39. 2011-11-21. PMID:21957248. |
the mesolimbic dopamine projection from the ventral tegmental area (vta) to the nucleus accumbens (nac) is critical in mediating reward-related behaviors, but the precise role of dopamine in this process remains unknown. |
2011-11-21 |
2023-08-12 |
Not clear |