| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Courtney M Cameron, Regina M Carell. Cocaine abstinence alters nucleus accumbens firing dynamics during goal-directed behaviors for cocaine and sucrose. The European journal of neuroscience. vol 35. issue 6. 2012-07-18. PMID:22356698. |
distinct subsets of nucleus accumbens (nac) neurons differentially encode goal-directed behaviors for natural vs. drug rewards [r. m. carelli et al. |
2012-07-18 |
2023-08-12 |
rat |
| Jun Fang, Jian-Wen Gu, Wen-Tao Yang, Xue-Ying Qin, Yong-Hua H. Clinical observation of physiological and psychological reactions to electric stimulation of the amygdaloid nucleus and the nucleus accumbens in heroin addicts after detoxification. Chinese medical journal. vol 125. issue 1. 2012-07-10. PMID:22340467. |
stereotactic surgery has been used to treat heroin abstinence in china since 2000 by ablating the amygdaloid nucleus (amy) and the nucleus accumbens (nac), which also provides opportunity to identify the relationship between these nuclei and addiction. |
2012-07-10 |
2023-08-12 |
Not clear |
| Lisa Wells, Jolanta Opacka-Juffry, Donald Fisher, Catherine Ledent, Susanna Hourani, Ian Kitche. In vivo dopaminergic and behavioral responses to acute cocaine are altered in adenosine A(2A) receptor knockout mice. Synapse (New York, N.Y.). vol 66. issue 5. 2012-07-09. PMID:22213208. |
changes in the extracellular levels of dopamine (da) in the nucleus accumbens (nac) of mice lacking a(2a) adenosine receptors and wild type (wt) littermates after an acute cocaine (20 mg/kg) administration were evaluated by in vivo microdialysis studies. |
2012-07-09 |
2023-08-12 |
mouse |
| Saïd Kourrich, Jason R Klug, Mark Mayford, Mark J Thoma. AMPAR-independent effect of striatal αCaMKII promotes the sensitization of cocaine reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 19. 2012-07-06. PMID:22573680. |
while behavior in rodent addiction models is linked with camkii activity in the nucleus accumbens (nac) shell, the key cellular adaptations that forge this link are unclear. |
2012-07-06 |
2023-08-12 |
mouse |
| Xiu-Juan Zhang, Man-Ying Xu, Ning L. [Influence of glutamate and NMDA-receptor antagonist MK-801 on the electric activities of pain-excitation neurons in the nucleus accumbens of rats]. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 1. 2012-06-28. PMID:15719138. |
the experiment explored the influence of glutamic acid (glu) and the nmda-receptor antagonist dizocilpine maleate (mk-801) on the pain-evoked responses of pain-excitation neurons (pen) in the nucleus accumbens (nac) of rats. |
2012-06-28 |
2023-08-12 |
rat |
| Amy L Loriaux, Jamie D Roitman, Mitchell F Roitma. Nucleus accumbens shell, but not core, tracks motivational value of salt. Journal of neurophysiology. vol 106. issue 3. 2012-06-26. PMID:21697439. |
the nucleus accumbens (nac) is a critical component of reward circuitry, but recent work suggests that the nac encodes aversion as well as reward. |
2012-06-26 |
2023-08-12 |
rat |
| Qian Bu, Yanzhu Yang, Guangyan Yan, Zhengtao Hu, Chunyan Hu, Jiachuan Duan, Lei Lv, Jiaqing Zhou, Jinxuan Zhao, Xue Shao, Yi Deng, Yan Li, Hongyu Li, Ruiming Zhu, Yinglan Zhao, Xiaobo Ce. Proteomic analysis of the nucleus accumbens in rhesus monkeys of morphine dependence and withdrawal intervention. Journal of proteomics. vol 75. issue 4. 2012-06-22. PMID:22123079. |
it has been known that the reinforcing effects and long-term consequences of morphine are closely associated with nucleus accumbens (nac) in the brain, a key region of the mesolimbic dopamine pathway. |
2012-06-22 |
2023-08-12 |
monkey |
| Samuel L Chong, Catherine M Claussen, Nachum Dafn. Nucleus accumbens neuronal activity in freely behaving rats is modulated following acute and chronic methylphenidate administration. Brain research bulletin. vol 87. issue 4-5. 2012-06-22. PMID:22248440. |
the nucleus accumbens (nac) has been implicated in regulating the rewarding effects of psychostimulants. |
2012-06-22 |
2023-08-12 |
rat |
| Jie Zhu, Yanjiong Chen, Na Zhao, Guofen Cao, Yonghui Dang, Wei Han, Ming Xu, Teng Che. Distinct roles of dopamine D3 receptors in modulating methamphetamine-induced behavioral sensitization and ultrastructural plasticity in the shell of the nucleus accumbens. Journal of neuroscience research. vol 90. issue 4. 2012-06-12. PMID:22420045. |
changes in dendritic morphology in the nucleus accumbens (nac) accompany drug-induced enduring behavioral and molecular changes, yet ultrastructural changes in synapses following repeated exposure to drugs have not been well studied. |
2012-06-12 |
2023-08-12 |
mouse |
| M Teresa Jurado-Parras, Agnès Gruart, José M Delgado-Garcí. Observational learning in mice can be prevented by medial prefrontal cortex stimulation and enhanced by nucleus accumbens stimulation. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 3. 2012-06-04. PMID:22354947. |
in contrast, electrical stimulation of the observer's nucleus accumbens (nac) enhances observational learning. |
2012-06-04 |
2023-08-12 |
mouse |
| Zivjena Vucetic, Jesse Lea Carlin, Kathy Totoki, Teresa M Reye. Epigenetic dysregulation of the dopamine system in diet-induced obesity. Journal of neurochemistry. vol 120. issue 6. 2012-06-01. PMID:22220805. |
dopamine (da) system changes in response to hf diet have been observed in the hypothalamus, important in the homeostatic control of food intake, as well as within the central reward circuitry [ventral tegmental area (vta), nucleus accumbens (nac), and pre-frontal cortex (pfc)], critical for coding the rewarding properties of palatable food and important in hedonically driven feeding behavior. |
2012-06-01 |
2023-08-12 |
mouse |
| Kenneth Blum, Eliot Gardner, Marlene Oscar-Berman, Mark Gol. "Liking" and "wanting" linked to Reward Deficiency Syndrome (RDS): hypothesizing differential responsivity in brain reward circuitry. Current pharmaceutical design. vol 18. issue 1. 2012-05-31. PMID:22236117. |
addictive drugs have in common that they are voluntarily selfadministered, they enhance (directly or indirectly) dopaminergic synaptic function in the nucleus accumbens (nac), and they stimulate the functioning of brain reward circuitry (producing the "high" that drug users seek). |
2012-05-31 |
2023-08-12 |
Not clear |
| Xing-Xiang Peng, Edward B Ziff, Kenneth D Car. Effects of food restriction and sucrose intake on synaptic delivery of AMPA receptors in nucleus accumbens. Synapse (New York, N.Y.). vol 65. issue 10. 2012-05-30. PMID:21425350. |
preclinical addiction research suggests that ampa receptor trafficking plays an important role in nucleus accumbens (nac) neuroplasticity underlying the compulsive and persistent quality of drug-seeking. |
2012-05-30 |
2023-08-12 |
human |
| Mohammad Reza Zarrindast, Morteza Piri, Mohammad Nasehi, Mohaddeseh Ebrahimi-Ghir. Nitric oxide in the nucleus accumbens is involved in retrieval of inhibitory avoidance memory by nicotine. Pharmacology, biochemistry, and behavior. vol 101. issue 1. 2012-05-25. PMID:22133634. |
in the present study, the possible effect of nitric oxide agents injected into the nucleus accumbens (nac) in the presence or absence of nicotine on morphine state-dependent memory in adult male wistar rats was investigated. |
2012-05-25 |
2023-08-12 |
rat |
| Sarah J Baracz, Poppy I Rourke, Margery C Pardey, Glenn E Hunt, Iain S McGregor, Jennifer L Cornis. Oxytocin directly administered into the nucleus accumbens core or subthalamic nucleus attenuates methamphetamine-induced conditioned place preference. Behavioural brain research. vol 228. issue 1. 2012-05-24. PMID:22155611. |
a fos immunohistochemistry study recently demonstrated that peripheral oxy administration reduced meth-induced fos expression within the nucleus accumbens (nac) core and subthalamic nucleus (sth) in rats. |
2012-05-24 |
2023-08-12 |
rat |
| James E McCutcheon, Jeff A Beeler, Mitchell F Roitma. Sucrose-predictive cues evoke greater phasic dopamine release than saccharin-predictive cues. Synapse (New York, N.Y.). vol 66. issue 4. 2012-05-21. PMID:22170625. |
cues that have been paired with food evoke dopamine in nucleus accumbens (nac) and drive approach behavior. |
2012-05-21 |
2023-08-12 |
rat |
| Catarina A Owesson-White, Mitchell F Roitman, Leslie A Sombers, Anna M Belle, Richard B Keithley, Jessica L Peele, Regina M Carelli, R Mark Wightma. Sources contributing to the average extracellular concentration of dopamine in the nucleus accumbens. Journal of neurochemistry. vol 121. issue 2. 2012-05-21. PMID:22296263. |
mesolimbic dopamine neurons fire in both tonic and phasic modes resulting in detectable extracellular levels of dopamine in the nucleus accumbens (nac). |
2012-05-21 |
2023-08-12 |
rat |
| Xue-Qin Zhang, Yu Cui, Yue Cui, Yu Chen, Xiao-Dong Na, Feng-Ying Chen, Xu-Hong Wei, Yong-Yong Li, Xian-Guo Liu, Wen-Jun Xi. Activation of p38 signaling in the microglia in the nucleus accumbens contributes to the acquisition and maintenance of morphine-induced conditioned place preference. Brain, behavior, and immunity. vol 26. issue 2. 2012-05-17. PMID:22004988. |
compared to well-defined roles of astrocyte in morphine cpp, the role of microglia in the nucleus accumbens (nac) remains poorly characterized. |
2012-05-17 |
2023-08-12 |
rat |
| Ruud van Zessen, Jana L Phillips, Evgeny A Budygin, Garret D Stube. Activation of VTA GABA neurons disrupts reward consumption. Neuron. vol 73. issue 6. 2012-05-15. PMID:22445345. |
in addition, direct activation of vta gaba projections to the nucleus accumbens (nac) resulted in detectable gaba release but did not alter reward consumption. |
2012-05-15 |
2023-08-12 |
Not clear |
| E A Budygin, J Park, C E Bass, V P Grinevich, K D Bonin, R M Wightma. Aversive stimulus differentially triggers subsecond dopamine release in reward regions. Neuroscience. vol 201. 2012-05-14. PMID:22108611. |
dopamine release is triggered in the dorsal striatum and nucleus accumbens (nac) core by tail pinch and is time locked to the duration of the stimulus, indicating that the dorsal striatum and nac core are neural substrates, which are involved in the perception of aversive stimuli. |
2012-05-14 |
2023-08-12 |
Not clear |