| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer L Warner-Schmidt, Eric F Schmidt, John J Marshall, Amanda J Rubin, Margarita Arango-Lievano, Michael G Kaplitt, Ines Ibañez-Tallon, Nathaniel Heintz, Paul Greengar. Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 28. 2012-10-05. PMID:22733786. |
a large number of studies have demonstrated that the nucleus accumbens (nac) is a critical site in the neuronal circuits controlling reward responses, motivation, and mood, but the neuronal cell type(s) underlying these processes are not yet known. |
2012-10-05 |
2023-08-12 |
mouse |
| Zhuo Liu, Jian-Jun Zhang, Xiao-Dong Liu, Long-Chuan Y. Inhibition of CaMKII activity in the nucleus accumbens shell blocks the reinstatement of morphine-seeking behavior in rats. Neuroscience letters. vol 518. issue 2. 2012-10-04. PMID:22579819. |
here, we explored the roles of camkii in the nucleus accumbens (nac) shell in the extinction and reinstatement of morphine-seeking behavior. |
2012-10-04 |
2023-08-12 |
rat |
| Shi-Lian Xu, Jun Li, Jian-Jun Zhang, Long-Chuan Y. Antinociceptive effects of galanin in the nucleus accumbens of rats. Neuroscience letters. vol 520. issue 1. 2012-10-04. PMID:22595465. |
the present study is performed to investigate the regulating role of galanin in nociception in the nucleus accumbens (nac) of rats. |
2012-10-04 |
2023-08-12 |
rat |
| Tünde Molnár, László Héja, Zsuzsa Emri, Agnes Simon, Gabriella Nyitrai, Ildikó Pál, Julianna Kardo. Activation of astroglial calcium signaling by endogenous metabolites succinate and gamma-hydroxybutyrate in the nucleus accumbens. Frontiers in neuroenergetics. vol 3. 2012-10-02. PMID:22180742. |
recently, astroglial ca(2+) transients evoked by the major citric acid cycle metabolite succinate (suc) and gamma-hydroxybutyrate (ghb) that enters the citric acid cycle via suc have been described in the brain reward area, the nucleus accumbens (nac). |
2012-10-02 |
2023-08-12 |
mouse |
| A Fink-Jensen, L Hansen, J B Hansen, E B Nielse. Regional differences in the effect of haloperidol and atypical neuroleptics on interstitial levels of DOPAC in the rat forebrain: an in vivo microdialysis study. Journal of psychopharmacology (Oxford, England). vol 10. issue 2. 2012-10-02. PMID:22302888. |
the effect of 'typical' and 'atypical' neuroleptics on interstitial levels of the dopamine metabolite 3,4- dihydroxyphenylacetic acid ([dopac]e) in the dorsolateral striatum (dlst), the nucleus accumbens (nac) and the medial prefrontal cortex (pfc) was investigated in awake rats by use of the microdialysis technique. |
2012-10-02 |
2023-08-12 |
rat |
| Luis Núñez-Jaramillo, José A Rangel-Hernández, Belén Burgueño-Zúñiga, María I Mirand. Activation of nucleus accumbens NMDA receptors differentially affects appetitive or aversive taste learning and memory. Frontiers in behavioral neuroscience. vol 6. 2012-10-02. PMID:22529783. |
taste memory depends on motivational and post-ingestional consequences; thus, it can be aversive (e.g., conditioned taste aversion, cta) if a novel, palatable taste is paired with visceral malaise, or it can be appetitive if no intoxication appears after novel taste consumption, and a taste preference is developed.the nucleus accumbens (nac) plays a role in hedonic reactivity to taste stimuli, and recent findings suggest that reward and aversion are differentially encoded by the activity of nac neurons. |
2012-10-02 |
2023-08-12 |
Not clear |
| Sarah K Bourne, Christine A Eckhardt, Sameer A Sheth, Emad N Eskanda. Mechanisms of deep brain stimulation for obsessive compulsive disorder: effects upon cells and circuits. Frontiers in integrative neuroscience. vol 6. 2012-10-02. PMID:22712007. |
to this end a number of dbs targets including the anterior limb of the internal capsule (alic), ventral capsule/ventral striatum (vc/vs), ventral caudate nucleus, subthalamic nucleus (stn), and nucleus accumbens (nac) have been investigated for the treatment of ocd. |
2012-10-02 |
2023-08-12 |
Not clear |
| Marina E Wolf, Kuei Y Tsen. Calcium-permeable AMPA receptors in the VTA and nucleus accumbens after cocaine exposure: when, how, and why? Frontiers in molecular neuroscience. vol 5. 2012-10-02. PMID:22754497. |
in animal models of drug addiction, cocaine exposure has been shown to increase levels of calcium-permeable ampa receptors (cp-ampars) in two brain regions that are critical for motivation and reward-the ventral tegmental area (vta) and the nucleus accumbens (nac). |
2012-10-02 |
2023-08-12 |
Not clear |
| Stefano Puglisi-Allegra, Rossella Ventur. Prefrontal/accumbal catecholamine system processes high motivational salience. Frontiers in behavioral neuroscience. vol 6. 2012-10-02. PMID:22754514. |
we have offered the first evidence that prefrontal cortical norepinephrine (ne) transmission is a necessary condition for motivational salience attribution to highly salient stimuli, through modulation of dopamine (da) in the nucleus accumbens (nac), a brain area involved in all motivated behaviors. |
2012-10-02 |
2023-08-12 |
Not clear |
| Soledad Cabeza de Vaca, Xing-Xiang Peng, Seth Concors, Casey Farin, Elena Lascu, Kenneth D Car. Effects of protein kinase A inhibitor and activator on rewarding effects of SKF-82958 microinjected into nucleus accumbens shell of ad libitum fed and food-restricted rats. Psychopharmacology. vol 221. issue 4. 2012-09-28. PMID:22143580. |
previous studies indicate that the rewarding effect of d-1 dopamine receptor stimulation in nucleus accumbens (nac) shell is greater in food-restricted (fr) than in ad libitum fed (al) rats. |
2012-09-28 |
2023-08-12 |
rat |
| Dorothy J Yamamoto, Nancy R Zahnise. Differences in rat dorsal striatal NMDA and AMPA receptors following acute and repeated cocaine-induced locomotor activation. PloS one. vol 7. issue 5. 2012-09-27. PMID:22655064. |
three areas involved in the development and expression of locomotor sensitization were investigated: the ventral tegmental area (vta), nucleus accumbens (nac) and dorsal striatum (dstr). |
2012-09-27 |
2023-08-12 |
rat |
| K D Fischer-Smith, A C W Houston, G V Rebe. Differential effects of cocaine access and withdrawal on glutamate type 1 transporter expression in rat nucleus accumbens core and shell. Neuroscience. vol 210. 2012-09-21. PMID:22433294. |
the relapse response requires increased glutamate transmission in the nucleus accumbens (nac). |
2012-09-21 |
2023-08-12 |
human |
| Lei Zhang, Juan Li, Nuyun Liu, Bin Wang, Jingjing Gu, Min Zhang, Zhitao Zhou, Yong Jiang, Lin Zhang, Lu Zhan. Signaling via dopamine D1 and D3 receptors oppositely regulates cocaine-induced structural remodeling of dendrites and spines. Neuro-Signals. vol 20. issue 1. 2012-09-20. PMID:22076064. |
here, we show that cocaine-induced structural remodeling in the nucleus accumbens (nac) and caudoputamen (cpu) is mediated by d1 receptors and inhibited by d3 receptors. |
2012-09-20 |
2023-08-12 |
Not clear |
| M Luisa Laorden, Szilamér Ferenczi, Bernadett Pintér-Kübler, Laura L González-Martín, M Carmen Lasheras, Krisztina J Kovács, M Victoria Milanés, Cristina Núñe. Hypothalamic orexin--a neurons are involved in the response of the brain stress system to morphine withdrawal. PloS one. vol 7. issue 5. 2012-09-19. PMID:22590628. |
importantly, sb334867 attenuated the somatic symptoms of withdrawal, and reduced morphine withdrawal-induced c-fos expression in the nucleus accumbens (nac) shell, bed nucleus of stria terminalis, central amygdala and hypothalamic paraventricular nucleus, but did not modify the hpa axis activity. |
2012-09-19 |
2023-08-12 |
rat |
| Juan Li, Nuyun Liu, Kangrong Lu, Lei Zhang, Jingjing Gu, Fukun Guo, Shengli An, Lin Zhang, Lu Zhan. Cocaine-induced dendritic remodeling occurs in both D1 and D2 dopamine receptor-expressing neurons in the nucleus accumbens. Neuroscience letters. vol 517. issue 2. 2012-09-14. PMID:22561554. |
repeated exposure to cocaine can induce persistent alterations in the brain's reward system, including increases in the number of dendrites and spine density on medium-sized spiny neurons (msns) in the nucleus accumbens (nac). |
2012-09-14 |
2023-08-12 |
mouse |
| Erik B Oleson, Mark J Ferris, Rodrigo A España, Jill Harp, Sara R Jone. Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward. European journal of pharmacology. vol 683. issue 1-3. 2012-09-13. PMID:22445882. |
aside from producing the desired histamine reducing effects, many antihistamines can also elicit psychomotor activation and reward, both of which are associated with increased dopamine concentrations in the nucleus accumbens (nac). |
2012-09-13 |
2023-08-12 |
Not clear |
| Nicole M Avena, Pedro V Rad. Cholinergic modulation of food and drug satiety and withdrawal. Physiology & behavior. vol 106. issue 3. 2012-09-13. PMID:22465312. |
in this review, we describe studies that suggest that the activity of cholinergic interneurons in the nucleus accumbens (nac) and cholinergic projections to the ventral tegmental area (vta) affect feeding behavior. |
2012-09-13 |
2023-08-12 |
rat |
| Mohammad-Reza Zarrindast, Saba Taheri, Ameneh Rezayo. The effects of histaminergic agents in the nucleus accumbens of rats in the elevated plus-maze test of anxiety. Iranian journal of psychiatry. vol 5. issue 1. 2012-09-06. PMID:22952484. |
the nucleus accumbens (nac) receive histaminergic neurons from tuberomammillary nuclei. |
2012-09-06 |
2023-08-12 |
rat |
| Andrew J D Nelson, Karen E Thur, Charles A Marsden, Helen J Cassada. Opposing effects of 5,7-DHT lesions to the core and shell of the nucleus accumbens on the processing of irrelevant stimuli. The international journal of neuropsychopharmacology. vol 15. issue 4. 2012-09-05. PMID:21557885. |
previous work has identified the nucleus accumbens (nac) as a key component of the neural circuit underpinning li and furthermore, this work has shown that the core and shell subregions of the nac contribute differentially to the expression of li. |
2012-09-05 |
2023-08-12 |
Not clear |
| Anne Marie Wissman, Renee M May, Catherine S Woolle. Ultrastructural analysis of sex differences in nucleus accumbens synaptic connectivity. Brain structure & function. vol 217. issue 2. 2012-09-04. PMID:21987050. |
despite robust sex differences in behavioral responses to drugs of abuse, relatively little is known about structural sex differences in synaptic connectivity of reward circuits such as in the nucleus accumbens (nac). |
2012-09-04 |
2023-08-12 |
rat |