| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Zhang, Jia Ni, Zhen-hua Chen, Xin Li, Ru-jun Zhang, Wei Tang, Wei-min Zhao, Yi-fu Yang, Jian-ping Zu. Periplocoside A prevents experimental autoimmune encephalomyelitis by suppressing IL-17 production and inhibits differentiation of Th17 cells. Acta pharmacologica Sinica. vol 30. issue 8. 2009-10-22. PMID:19597527. |
the aim of this study was to determine the therapeutic effect of periplocoside a (psa), a natural product isolated from the traditional chinese herbal medicine periploca sepium bge, in mog(35-55) (myelin oligodendrocyte glycoprotein 35-55)-induced experimental autoimmune encephalomyelitis (eae). |
2009-10-22 |
2023-08-12 |
Not clear |
| Katherine A McLaughlin, Tanuja Chitnis, Jia Newcombe, Bettina Franz, Julia Kennedy, Shannon McArdel, Jens Kuhle, Ludwig Kappos, Kevin Rostasy, Daniela Pohl, Donald Gagne, Jayne M Ness, Silvia Tenembaum, Kevin C O'Connor, Vissia Viglietta, Susan J Wong, Norma P Tavakoli, Jerome de Seze, Zhannat Idrissova, Samia J Khoury, Amit Bar-Or, David A Hafler, Brenda Banwell, Kai W Wucherpfenni. Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis. Journal of immunology (Baltimore, Md. : 1950). vol 183. issue 6. 2009-09-23. PMID:19687098. |
although abs to native myelin oligodendrocyte glycoprotein (mog) were uncommon among adult-onset patients, a subset of pediatric patients had serum abs that brightly labeled the mog transfectant. |
2009-09-23 |
2023-08-12 |
human |
| Benjamin M Sega. Getting to the crux of the matter: IL-23 and Th17 cell accumulation in the CNS. European journal of immunology. vol 39. issue 7. 2009-09-18. PMID:19582738. |
il-23 plays a critical role in eae induced by the active immunization of c57bl/6 mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein (mog(35-55)). |
2009-09-18 |
2023-08-12 |
mouse |
| Taku Kuwabara, Fumio Ishikawa, Takuwa Yasuda, Kentaro Aritomi, Hideki Nakano, Yuriko Tanaka, Yayoi Okada, Martin Lipp, Terutaka Kakiuch. CCR7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells. Journal of immunology (Baltimore, Md. : 1950). vol 183. issue 4. 2009-09-09. PMID:19625643. |
c57bl/6 mice lacking expression of these chemokines (plt/plt mice) or their receptor ccr7 were resistant to eae induced with myelin oligodendrocyte glycoprotein peptide 35-55 (mog(35-55)) and pertussis toxin. |
2009-09-09 |
2023-08-12 |
mouse |
| Kristofor K Ellestad, Shigeki Tsutsui, Farshid Noorbakhsh, Kenneth G Warren, V Wee Yong, Quentin J Pittman, Christopher Powe. Early life exposure to lipopolysaccharide suppresses experimental autoimmune encephalomyelitis by promoting tolerogenic dendritic cells and regulatory T cells. Journal of immunology (Baltimore, Md. : 1950). vol 183. issue 1. 2009-08-20. PMID:19542441. |
mice exposed to lps at 2 wk of age showed a delayed onset and diminished severity of myelin oligodendrocyte glycoprotein (mog)-induced eae, induced at 12 wk, compared with vehicle-exposed animals. |
2009-08-20 |
2023-08-12 |
mouse |
| I Kurkowska-Jastrzebska, E Bałkowiec-Iskra, A Ciesielska, I Joniec, A Cudna, M M Zaremba, A Członkowski, A Członkowsk. Decreased inflammation and augmented expression of trophic factors correlate with MOG-induced neuroprotection of the injured nigrostriatal system in the murine MPTP model of Parkinson's disease. International immunopharmacology. vol 9. issue 6. 2009-08-17. PMID:19286483. |
injections of mptp (40 mg/kg) and some groups animals also received an additional injection with myelin oligodendrocyte glycoprotein (mog) 35-55 in cfa 6 days before mptp administration. |
2009-08-17 |
2023-08-12 |
mouse |
| Ulf Schulze-Topphoff, Alexandre Prat, Timour Prozorovski, Volker Siffrin, Magdalena Paterka, Josephine Herz, Ivo Bendix, Igal Ifergan, Ines Schadock, Marcelo A Mori, Jack Van Horssen, Friederike Schröter, Alina Smorodchenko, May Htwe Han, Michael Bader, Lawrence Steinman, Orhan Aktas, Frauke Zip. Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system. Nature medicine. vol 15. issue 7. 2009-07-27. PMID:19561616. |
bdkrb1-deficient (bdkrb1(-/-)) c57bl/6 mice immunized with a myelin oligodendrocyte glycoprotein fragment, mog(35-55), showed more severe disease with enhanced cns-immune cell infiltration. |
2009-07-27 |
2023-08-12 |
mouse |
| Gurumoorthy Krishnamoorthy, Amit Saxena, Lennart T Mars, Helena S Domingues, Reinhard Mentele, Avraham Ben-Nun, Hans Lassmann, Klaus Dornmair, Florian C Kurschus, Roland S Liblau, Hartmut Wekerl. Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis. Nature medicine. vol 15. issue 6. 2009-07-23. PMID:19483694. |
we describe here the paradoxical development of spontaneous experimental autoimmune encephalomyelitis (eae) in transgenic mice expressing a myelin oligodendrocyte glycoprotein (mog)-specific t cell antigen receptor (tcr) in the absence of mog. |
2009-07-23 |
2023-08-12 |
mouse |
| Monica Marta, Ute C Meier, Anna Lobel. Regulation of autoimmune encephalomyelitis by toll-like receptors. Autoimmunity reviews. vol 8. issue 6. 2009-07-17. PMID:19211042. |
tlr9 down regulates disease severity in myelin oligodendrocyte glycoprotein (mog)-induced eae, whereas it promotes disease in mog(35-55)-induced eae. |
2009-07-17 |
2023-08-12 |
mouse |
| Florencia Labombarda, Susana L González, Analia Lima, Paulina Roig, Rachida Guennoun, Michael Schumacher, Alejandro F de Nicol. Effects of progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury. Glia. vol 57. issue 8. 2009-07-09. PMID:19053058. |
short progesterone treatment (a) increased the number of opc without effect on the injury-induced reduction of mature oligodendrocytes, (b) increased mrna and protein expression for the myelin basic protein (mbp) without effects on proteolipid protein (plp) or myelin oligodendrocyte glycoprotein (mog), and (c) increased the mrna for olig2 and nkx2.2 transcription factors involved in specification and differentiation of the oligodendrocyte lineage. |
2009-07-09 |
2023-08-12 |
rat |
| Bernadette Pöllinger, Gurumoorthy Krishnamoorthy, Kerstin Berer, Hans Lassmann, Michael R Bösl, Robert Dunn, Helena S Domingues, Andreas Holz, Florian C Kurschus, Hartmut Wekerl. Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells. The Journal of experimental medicine. vol 206. issue 6. 2009-07-07. PMID:19487416. |
we describe new t cell receptor (tcr) transgenic mice (relapsing-remitting [rr] mice) carrying a tcr specific for myelin oligodendrocyte glycoprotein (mog) peptide 92-106 in the context of i-a(s). |
2009-07-07 |
2023-08-12 |
mouse |
| Melanie Thessen Hedreul, Alan Gillett, Tomas Olsson, Maja Jagodic, Robert A Harri. Characterization of Multiple Sclerosis candidate gene expression kinetics in rat experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 210. issue 1-2. 2009-07-06. PMID:19269041. |
we thus aimed to determine the kinetic expression of several multiple sclerosis (ms) candidate genes in the myelin oligodendrocyte glycoprotein (mog)-induced rat experimental autoimmune encephalomyelitis (eae) model using susceptible da and resistant pvg inbred strains. |
2009-07-06 |
2023-08-12 |
human |
| Kaiyong Yang, Jose L Vega, Muhamed Hadzipasic, Jean Pierre Schatzmann Peron, Bing Zhu, Yijun Carrier, Sharmila Masli, Luiz Vicente Rizzo, Howard L Weine. Deficiency of thrombospondin-1 reduces Th17 differentiation and attenuates experimental autoimmune encephalomyelitis. Journal of autoimmunity. vol 32. issue 2. 2009-06-26. PMID:19181483. |
upon immunization with myelin oligodendrocyte glycoprotein peptide (mog(35-55)), tsp-1 deficient (tsp-1(null)) mice and mog(35-55) tcr transgenic mice that lack of tsp-1 (2d2 x tsp-1(null)) exhibited an attenuated form of eae, and secreted lower levels of il-17. |
2009-06-26 |
2023-08-12 |
mouse |
| Bing Li, Joseph M Reynolds, Robert D Stout, David A Bernlohr, Jill Suttle. Regulation of Th17 differentiation by epidermal fatty acid-binding protein. Journal of immunology (Baltimore, Md. : 1950). vol 182. issue 12. 2009-06-25. PMID:19494286. |
in response to immunization with myelin oligodendrocyte glycoprotein peptide (mog(35-55)), e-fabp-deficient mice generated reduced levels of th17 cells and elevated levels of tregs, as compared with wild-type mice. |
2009-06-25 |
2023-08-12 |
mouse |
| Antje Kroner, Nicholas Schwab, Chi Wang Ip, Sonja Ortler, Kerstin Göbel, Klaus-Armin Nave, Mathias Mäurer, Rudolf Martini, Heinz Wiend. Accelerated course of experimental autoimmune encephalomyelitis in PD-1-deficient central nervous system myelin mutants. The American journal of pathology. vol 174. issue 6. 2009-06-23. PMID:19443704. |
we challenged this concept experimentally by investigating how genetic alterations that affect myelin (primary oligodendrocyte damage in plptg mice) and/or t-cell regulation (deficiency of pd-1) influence both the onset and course of an experimental autoimmune cns inflammatory disease [mog(35-55)-induced experimental autoimmune encephalomyelitis (eae)]. |
2009-06-23 |
2023-08-12 |
mouse |
| W A Roscoe, M E Welsh, D E Carter, S J Karli. VEGF and angiogenesis in acute and chronic MOG((35-55)) peptide induced EAE. Journal of neuroimmunology. vol 209. issue 1-2. 2009-06-22. PMID:19233483. |
the purpose of this study was to investigate the vascular changes in acute and chronic eae in c57bl/6 mice induced with myelin oligodendrocyte glycoprotein (mog ((35-55))) peptide. |
2009-06-22 |
2023-08-12 |
mouse |
| Ruth Huizinga, Rogier Q Hintzen, Karin Assink, Marjan van Meurs, Sandra Amo. T-cell responses to neurofilament light protein are part of the normal immune repertoire. International immunology. vol 21. issue 4. 2009-06-05. PMID:19240089. |
here, we identify and characterize t-cell proliferative responses to nf-l as compared with myelin oligodendrocyte glycoprotein (mog) in ms patients and healthy controls. |
2009-06-05 |
2023-08-12 |
mouse |
| Silvia Musio, Paola Pedotti, Renato Mantegazza, Hiroshi Ohtsu, Louis Boon, Lawrence Steinman, Stephen J Galli, Rosetta Pedott. Anaphylaxis to a self-peptide in the absence of mast cells or histamine. Laboratory investigation; a journal of technical methods and pathology. vol 89. issue 4. 2009-05-15. PMID:19188909. |
here we show that systemic anaphylaxis to the self-antigen myelin oligodendrocyte glycoprotein (mog) 35-55 can occur in mice lacking mast cells (kit(w)/kit(w-v) mice) or histamine (histidine decarboxylase-deficient mice), but is prevented in mice lacking il-4. |
2009-05-15 |
2023-08-12 |
mouse |
| Lisa K Peterson, Takahisa Masaki, Steven R Wheelwright, Ikuo Tsunoda, Robert S Fujinam. Cross-reactive myelin antibody induces renal pathology. Autoimmunity. vol 41. issue 7. 2009-05-11. PMID:18608179. |
previously, we reported renal immunoglobulin (ig) deposition in mice with myelin oligodendrocyte glycoprotein (mog(92-106))-induced progressive eae and naive mice injected with mog(92-106) hybridoma cells producing antibody that cross-reacts with various autoantigens including double-stranded dna. |
2009-05-11 |
2023-08-12 |
mouse |
| Mark Mannie, Robert H Swanborg, Jolie A Stepania. Experimental autoimmune encephalomyelitis in the rat. Current protocols in immunology. vol Chapter 15. 2009-05-07. PMID:19347844. |
these models enable the study of encephalitogenic t cells and demyelinating antibody specific for major neuroantigens such as myelin basic protein (mbp), myelin oligodendrocyte glycoprotein (mog), or proteolipid protein (plp), among other important cns autoantigens. |
2009-05-07 |
2023-08-12 |
rat |