| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eva Herrero-Herranz, Luis A Pardo, Ralf Gold, Ralf A Linke. Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: implications for multiple sclerosis. Neurobiology of disease. vol 30. issue 2. 2008-10-13. PMID:18342527. |
here we investigate the pattern of axonal injury in murine myelin oligodendrocyte glycoprotein peptide 35-55 (mog) induced eae. |
2008-10-13 |
2023-08-12 |
human |
| Hongmei Li, Guang-Xian Zhang, Youhai Chen, Hui Xu, Denise C Fitzgerald, Zhao Zhao, Abdolmohamad Rostam. CD11c+CD11b+ dendritic cells play an important role in intravenous tolerance and the suppression of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 181. issue 4. 2008-10-06. PMID:18684939. |
with an autoantigen peptide of myelin oligodendrocyte glycoprotein (mog) developed less severe experimental autoimmune encephalomyelitis (eae) following immunization with mog peptide but presented with more cd11c(+)cd11b(+) dcs in the cns and spleen. |
2008-10-06 |
2023-08-12 |
mouse |
| Marcio L De Paula, David H Rodrigues, Henrique C Teixeira, Michele M Barsante, Maria A Souza, Ana P Ferreir. Genistein down-modulates pro-inflammatory cytokines and reverses clinical signs of experimental autoimmune encephalomyelitis. International immunopharmacology. vol 8. issue 9. 2008-10-03. PMID:18602076. |
in the present report, we investigated the use of genistein for the treatment of the murine model of ms. after induction of eae with myelin oligodendrocyte glycoprotein 35-55 peptide (mog(35-55)), we observed that genistein treatment ameliorated significantly the clinical symptoms, modulating pro- and anti-inflammatory cytokines. |
2008-10-03 |
2023-08-12 |
human |
| Cecilia B Marta, Rashmi Bansal, Steven E Pfeiffe. Microglial Fc receptors mediate physiological changes resulting from antibody cross-linking of myelin oligodendrocyte glycoprotein. Journal of neuroimmunology. vol 196. issue 1-2. 2008-09-24. PMID:18406472. |
antibodies to myelin oligodendrocyte glycoprotein (mog) have been implicated in multiple sclerosis demyelination through activation of complement and/or macrophage-effector processes. |
2008-09-24 |
2023-08-12 |
Not clear |
| Marcin P Mycko, Hanna Cwiklinska, Agata Walczak, Claude Libert, Cedric S Raine, Krzysztof W Selma. A heat shock protein gene (Hsp70.1) is critically involved in the generation of the immune response to myelin antigen. European journal of immunology. vol 38. issue 7. 2008-09-02. PMID:18581325. |
hsp70.1(-/-) mice sensitized for experimental autoimmune encephalomyelitis (eae) with myelin oligodendrocyte glycoprotein (mog) peptide 35-55, displayed almost complete resistance to the disease. |
2008-09-02 |
2023-08-12 |
mouse |
| Andre M Mueller, Xiomara Pedré, Thomas Stempfl, Ingo Kleiter, Sebastien Couillard-Despres, Ludwig Aigner, Gerhard Giegerich, Andreas Steinbreche. Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis. Journal of neuroinflammation. vol 5. 2008-08-21. PMID:18501024. |
experimental autoimmune encephalomyelitis (eae) induced by myelin oligodendrocyte protein (mog) in female dark agouti (da) rats is a chronic demyelinating animal model of multiple sclerosis (ms). |
2008-08-21 |
2023-08-12 |
rat |
| Sonja Ortler, Christoph Leder, Michel Mittelbronn, Alla L Zozulya, Percy A Knolle, Lieping Chen, Antje Kroner, Heinz Wiend. B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis. European journal of immunology. vol 38. issue 6. 2008-08-18. PMID:18421793. |
to understand the b7-h1/pd1 pathway in cns inflammation, we analyzed adaptive immune responses in myelin oligodendrocyte glycoprotein (mog)(35-55)-induced eae and assessed the expression of b7-h1 in human cns tissue. |
2008-08-18 |
2023-08-12 |
mouse |
| Constanze Breithaupt, Beatrix Schäfer, Hannah Pellkofer, Robert Huber, Christopher Linington, Uwe Jaco. Demyelinating myelin oligodendrocyte glycoprotein-specific autoantibody response is focused on one dominant conformational epitope region in rodents. Journal of immunology (Baltimore, Md. : 1950). vol 181. issue 2. 2008-08-12. PMID:18606679. |
conformational epitopes of myelin oligodendrocyte glycoprotein (mog) provide a major target for demyelinating autoantibodies in experimental autoimmune encephalomyelitis and recent studies indicate that a similar situation may exist in multiple sclerosis. |
2008-08-12 |
2023-08-12 |
mouse |
| Satoshi Serada, Minoru Fujimoto, Masahiko Mihara, Nobuo Koike, Yoshiyuki Ohsugi, Shintaro Nomura, Hiroto Yoshida, Teppei Nishikawa, Fumitaka Terabe, Tomoharu Ohkawara, Tsuyoshi Takahashi, Barry Ripley, Akihiro Kimura, Tadamitsu Kishimoto, Tetsuji Nak. IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 26. 2008-07-31. PMID:18577591. |
in the present study, we found that il-6 blockade by treatment with an anti-il-6 receptor monoclonal antibody (anti-il-6r mab) inhibited the development of eae and inhibited the induction of myelin oligodendrocyte glycoprotein (mog) peptide-specific cd4-positive, cd8-positive, and th17 t cells, in inguinal lymph nodes. |
2008-07-31 |
2023-08-12 |
human |
| Ilaria Luccarini, Clara Ballerini, Tiziana Biagioli, Filippo Biamonte, Arianna Bellucci, Maria Cristina Rosi, Cristina Grossi, Luca Massacesi, Fiorella Casament. Combined treatment with atorvastatin and minocycline suppresses severity of EAE. Experimental neurology. vol 211. issue 1. 2008-07-30. PMID:18346732. |
in this study, we tested whether the combination of these two drugs could produce beneficial effects in eae mice immunized with myelin oligodendrocyte protein (mog). |
2008-07-30 |
2023-08-12 |
mouse |
| Lisa K Peterson, Ikuo Tsunoda, Jane E Libbey, Robert S Fujinam. Role of B:T cell ratio in suppression of clinical signs: a model for silent MS. Experimental and molecular pathology. vol 85. issue 1. 2008-07-22. PMID:18486939. |
however, sensitization with a myelin oligodendrocyte glycoprotein (mog) peptide, mog(92-106), induced clinical signs in 30% of mice and central nervous system (cns) pathology in 93% of mice. |
2008-07-22 |
2023-08-12 |
mouse |
| James Chan, Ee Jun Ban, Keng Hao Chun, Shunhe Wang, Jonathan McQualter, Claude Bernard, Ban-Hock Toh, Frank Alderucci. Methylprednisolone induces reversible clinical and pathological remission and loss of lymphocyte reactivity to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis. Autoimmunity. vol 41. issue 5. 2008-07-21. PMID:18568646. |
here, we examined the effect of oral methylprednisolone on the mouse eae model of human ms induced by immunisation with myelin oligodendrocyte glycoprotein peptide (mog(35-55)). |
2008-07-21 |
2023-08-12 |
mouse |
| Heather A Wasserman, Brian D Evavol. Induction of anergy by antibody blockade of TCR in myelin oligodendrocyte glycoprotein-specific cells. Journal of immunology (Baltimore, Md. : 1950). vol 180. issue 11. 2008-07-18. PMID:18490725. |
after masking the tcr with either continuous or prepulsed anti-valpha3.2 ab, 2d2 cells were immediately stimulated with myelin oligodendrocyte glycoprotein (mog)(35-55). |
2008-07-18 |
2023-08-12 |
mouse |
| Thomas Nachreiner, Florian Kampmeier, Theo Thepen, Rainer Fischer, Stefan Barth, Michael Stöcke. Depletion of autoreactive B-lymphocytes by a recombinant myelin oligodendrocyte glycoprotein-based immunotoxin. Journal of neuroimmunology. vol 195. issue 1-2. 2008-07-10. PMID:18280586. |
we report the construction of a fusion protein comprising the extracellular domain of myelin oligodendrocyte glycoprotein (mog) and a truncated version of pseudomonas aeruginosa exotoxin a (eta'). |
2008-07-10 |
2023-08-12 |
mouse |
| Yasunori Uemura, Hiroaki Ohno, Yumiko Ohzeki, Hiromi Takanashi, Hideko Murooka, Kazuo Kubo, Isao Serizaw. The selective M-CSF receptor tyrosine kinase inhibitor Ki20227 suppresses experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 195. issue 1-2. 2008-07-10. PMID:18378004. |
experimental autoimmune encephalomyelitis (eae), an animal model of multiple sclerosis (ms), can be induced by the immunization of mice with myelin antigens in the form of myelin oligodendrocyte glycoprotein (mog). |
2008-07-10 |
2023-08-12 |
mouse |
| B Dabrowska-Bouta, L Struzyńska, M Walski, U Rafałowsk. Myelin glycoproteins targeted by lead in the rodent model of prolonged exposure. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 46. issue 3. 2008-06-03. PMID:18077072. |
the aim of these experiments was to discern whether prolonged exposure of rats to lead (pb) in water, as occurs in typical environmental exposure, affects the structure of myelin in the brain, the protein levels of the myelin glycoproteins myelin associated glycoprotein (mag) and myelin oligodendrocyte glycoprotein (mog). |
2008-06-03 |
2023-08-12 |
rat |
| Joseph J Sabatino, John Shires, John D Altman, Mandy L Ford, Brian D Evavol. Loss of IFN-gamma enables the expansion of autoreactive CD4+ T cells to induce experimental autoimmune encephalomyelitis by a nonencephalitogenic myelin variant antigen. Journal of immunology (Baltimore, Md. : 1950). vol 180. issue 7. 2008-05-30. PMID:18354166. |
recently, our laboratory demonstrated that immunization of wt b6 mice with 45d, a low-affinity mhc variant peptide of mog(35-55), results in significantly attenuated experimental autoimmune encephalomyelitis (eae), yet ifn-gamma production is comparable to myelin oligodendrocyte glycoprotein (mog)(35-55)-immunized mice. |
2008-05-30 |
2023-08-12 |
mouse |
| Trina A Johnson, Shigeki Tsutsui, Frank R Jiri. Antigen-induced Pten gene deletion in T cells exacerbates neuropathology in experimental autoimmune encephalomyelitis. The American journal of pathology. vol 172. issue 4. 2008-05-14. PMID:18349128. |
compared with pten(fl/fl) controls, myelin oligodendrocyte glycoprotein (mog) peptide-immunized pten(fl/fl) gbc mice developed more severe and protracted disease. |
2008-05-14 |
2023-08-12 |
mouse |
| Stefanie Kuerten, Doychin N Angelo. Comparing the CNS morphology and immunobiology of different EAE models in C57BL/6 mice - a step towards understanding the complexity of multiple sclerosis. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 190. issue 1. 2008-05-06. PMID:18342137. |
myelin basic protein-proteolipid protein (mbp-plp) fusion protein (mp4)-, myelin oligodendrocyte glycoprotein (mog) peptide 35-55- and plp peptide 178-191-induced eae, can facilitate our understanding of the complexity of ms. we point out how the development of further models on this basis can help cover the plethora of disease manifestations seen in ms. |
2008-05-06 |
2023-08-12 |
mouse |
| R K Burfoot, C J Jensen, J Field, J Stankovich, M D Varney, L J Johnson, H Butzkueven, D Booth, M Bahlo, B D Tait, B V Taylor, T P Speed, R Heard, G J Stewart, S J Foote, T J Kilpatrick, J P Rubi. SNP mapping and candidate gene sequencing in the class I region of the HLA complex: searching for multiple sclerosis susceptibility genes in Tasmanians. Tissue antigens. vol 71. issue 1. 2008-04-30. PMID:17971048. |
single nucleotide polymorphism (snp) mapping was performed on an 865-kb candidate region (d6s1683-d6s265) in 166 tasmanian ms families, and seven candidate genes [ubiquitin d (ubd), olfactory receptor 2h3 (or2h3), gamma-aminobutyric acid b receptor 1 (gabbr1), myelin oligodendrocyte glycoprotein (mog), hla-f, hla complex group 4 (hcg4) and hla-g] were resequenced. |
2008-04-30 |
2023-08-12 |
human |