| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoh Matsumoto, Il-Kwon Park, Keiko Hiraki, Shin Ohtani, Kuniko Kohyam. Role of pathogenic T cells and autoantibodies in relapse and progression of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis in LEW.1AV1 rats. Immunology. vol 128. issue 1 Suppl. 2010-01-25. PMID:19175799. |
accumulating evidence suggests that t cells and autoantibodies reactive with myelin oligodendrocyte glycoprotein (mog) play a critical role in the pathogenesis of multiple sclerosis (ms). |
2010-01-25 |
2023-08-12 |
rat |
| Nóra Terényi, Nándor Nagy, Krisztián Papp, József Prechl, Imre Oláh, Anna Erde. Transient decomplementation of mice delays onset of experimental autoimmune encephalomyelitis and impairs MOG-specific T cell response and autoantibody production. Molecular immunology. vol 47. issue 1. 2010-01-25. PMID:19201476. |
our results show that in decomplemented c57bl/6 mice immunized with myelin oligodendrocyte glycoprotein (mog) peptide 35-55, the onset of the disease is significantly delayed. |
2010-01-25 |
2023-08-12 |
mouse |
| Carlo Guardiani, Simone Marsili, Piero Procacci, Roberto Liv. Fragment 101-108 of myelin oligodendrocyte glycoprotein: a possible lead compound for multiple sclerosis. Journal of the American Chemical Society. vol 131. issue 47. 2010-01-21. PMID:19891505. |
one of the potential targets of the autoimmune reaction is the myelin protein mog (myelin oligodendrocyte glycoprotein). |
2010-01-21 |
2023-08-12 |
Not clear |
| Fabienne Brilot, Russell C Dale, Rebecca C Selter, Verena Grummel, Sudhakar Reddy Kalluri, Muhammad Aslam, Verena Busch, Dun Zhou, Sabine Cepok, Bernhard Hemme. Antibodies to native myelin oligodendrocyte glycoprotein in children with inflammatory demyelinating central nervous system disease. Annals of neurology. vol 66. issue 6. 2010-01-18. PMID:20033986. |
myelin oligodendrocyte glycoprotein (mog) is a candidate target antigen in demyelinating diseases of the central nervous system (cns). |
2010-01-18 |
2023-08-12 |
human |
| Shmuel J Cohen, Irun R Cohen, Gabriel Nussbau. IL-10 mediates resistance to adoptive transfer experimental autoimmune encephalomyelitis in MyD88(-/-) mice. Journal of immunology (Baltimore, Md. : 1950). vol 184. issue 1. 2010-01-08. PMID:19949074. |
mice lacking myd88, for example, resist active experimental autoimmune encephalomyelitis (eae) induced by immunization with an encephalitogenic myelin oligodendrocyte glycoprotein (mog) peptide in cfa. |
2010-01-08 |
2023-08-12 |
mouse |
| Mei-Ling Chen, Bo-Shiun Yan, Deneen Kozoriz, Howard L Weine. Novel CD8+ Treg suppress EAE by TGF-beta- and IFN-gamma-dependent mechanisms. European journal of immunology. vol 39. issue 12. 2010-01-06. PMID:19768696. |
in an adoptive co-transfer model, cd8+lap+ cells suppress myelin oligodendrocyte glycoprotein (mog)-specific immune responses by inducing or expanding foxp3+ cells and by inhibiting proliferation and ifn-gamma production in vivo. |
2010-01-06 |
2023-08-12 |
mouse |
| Georgina Galicia, Wim Maes, Bert Verbinnen, Ahmad Kasran, Dominique Bullens, Mohamed Arredouani, Jan L Ceuppen. Haptoglobin deficiency facilitates the development of autoimmune inflammation. European journal of immunology. vol 39. issue 12. 2010-01-06. PMID:19795414. |
to analyze hp's effect on autoimmune inflammation, we here studied the course of eae induced by immunization of hp knockout (hp(-/-)) and syngeneic wt mice with myelin oligodendrocyte glycoprotein peptide (mog(35-55)). |
2010-01-06 |
2023-08-12 |
mouse |
| Nic D Leipzig, Molly S Shoiche. The effect of substrate stiffness on adult neural stem cell behavior. Biomaterials. vol 30. issue 36. 2010-01-05. PMID:19775749. |
oligodendrocyte differentiation was favored on stiffer scaffolds (> 7 kpa); however, myelin oligodendrocyte glycoprotein (mog) gene expression suggested that oligodendrocyte maturation and myelination was best on < 1 kpa scaffolds where more mature neurons were present. |
2010-01-05 |
2023-08-12 |
Not clear |
| Akiko Oyamada, Hiori Ikebe, Momoe Itsumi, Hirokazu Saiwai, Seiji Okada, Kazuya Shimoda, Yoichiro Iwakura, Keiichi I Nakayama, Yukihide Iwamoto, Yasunobu Yoshikai, Hisakata Yamad. Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 183. issue 11. 2009-12-22. PMID:19917699. |
in the present study, we examined the roles of tyk2 in the development of myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae) by using tyk2 knockout (ko) mice. |
2009-12-22 |
2023-08-12 |
mouse |
| Yukio Sekiguchi, Motoki Ichikawa, Masaya Takamoto, Hiroyoshi Ota, Chang-Sung Koh, Masamichi Muramatsu, Tasuku Honjo, Kazunaga Agemats. Antibodies to myelin oligodendrocyte glycoprotein are not involved in the severity of chronic non-remitting experimental autoimmune encephalomyelitis. Immunology letters. vol 122. issue 2. 2009-12-16. PMID:18824198. |
to elucidate the role of antibodies in development of chronic non-remitting experimental autoimmune encephalomyelitis (eae) in c57bl/6 mice, which is a well-established th1-mediated autoimmune disease, and the involvement of activation-induced cytidine deaminase (aid) in th1-mediated function, we have investigated the myelin oligodendrocyte glycoprotein (mog)-induced eae in mice deficient of aid, which is absolutely required for class switching and somatic hypermutation. |
2009-12-16 |
2023-08-12 |
mouse |
| Shyi-Jou Chen, Yen-Lin Wang, Jen-Hsin Kao, Shu-Feng Wu, Wen-Tsung Lo, Chia-Cho Wu, Pao-Luh Tao, Chih-Chien Wang, Deh-Ming Chang, Huey-Kang Sytw. Decoy receptor 3 ameliorates experimental autoimmune encephalomyelitis by directly counteracting local inflammation and downregulating Th17 cells. Molecular immunology. vol 47. issue 2-3. 2009-12-16. PMID:19819554. |
myelin oligodendrocyte glycoprotein (mog)-specific t cell proliferation was significantly inhibited in dcr3-treated mice. |
2009-12-16 |
2023-08-12 |
mouse |
| Angelo H All, Piotr Walczak, Gracee Agrawal, Michael Gorelik, Christopher Lee, Nitish V Thakor, Jeff W M Bulte, Douglas A Ker. Effect of MOG sensitization on somatosensory evoked potential in Lewis rats. Journal of the neurological sciences. vol 284. issue 1-2. 2009-12-15. PMID:19423134. |
myelin oligodendrocyte glycoprotein (mog) is commonly used as an immunogen to induce an immune response against endogenous myelin, thereby modeling multiple sclerosis in rodents. |
2009-12-15 |
2023-08-12 |
rat |
| Mayumi Fujita, Takao Otsuka, Miho Mizuno, Chiharu Tomi, Takashi Yamamura, Sachiko Miyak. Carcinoembryonic antigen-related cell adhesion molecule 1 modulates experimental autoimmune encephalomyelitis via an iNKT cell-dependent mechanism. The American journal of pathology. vol 175. issue 3. 2009-12-14. PMID:19700760. |
treatment of c57bl/6j mice with ceacam1-fc fusion protein, a homophilic ligand of ceacam1, inhibited the severity of eae and reduced myelin oligodendrocyte glycoprotein-derived peptide (mog(35-55))-reactive interferon-gamma and interleukin-17 production. |
2009-12-14 |
2023-08-12 |
mouse |
| Silvia Rossi, Roberto Furlan, Valentina De Chiara, Alessandra Musella, Temistocle Lo Giudice, Giorgia Mataluni, Francesca Cavasinni, Cristina Cantarella, Giorgio Bernardi, Luca Muzio, Alessandro Martorana, Gianvito Martino, Diego Centonz. Exercise attenuates the clinical, synaptic and dendritic abnormalities of experimental autoimmune encephalomyelitis. Neurobiology of disease. vol 36. issue 1. 2009-12-07. PMID:19591937. |
in the present study, we evaluated the clinical, synaptic and neuropathological effects of voluntary wheel running in mice with myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae), a model of multiple sclerosis. |
2009-12-07 |
2023-08-12 |
mouse |
| Kareem L Graham, Brian A Zabel, Sanam Loghavi, Luis A Zuniga, Peggy P Ho, Raymond A Sobel, Eugene C Butche. Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease. Journal of immunology (Baltimore, Md. : 1950). vol 183. issue 10. 2009-12-07. PMID:19864606. |
upon eae induction by active immunization with myelin oligodendrocyte glycoprotein amino acids 35-55 (mog(35-55)), microglial cells and cns-infiltrating myeloid dendritic cells expressed cmklr1, as determined by flow cytometric analysis. |
2009-12-07 |
2023-08-12 |
mouse |
| Yukie Aizawa, Nic Leipzig, Tasneem Zahir, Molly Shoiche. The effect of immobilized platelet derived growth factor AA on neural stem/progenitor cell differentiation on cell-adhesive hydrogels. Biomaterials. vol 29. issue 35. 2009-11-30. PMID:18801569. |
interestingly, the gene expression of the differentiated oligodendrocytes was similar for 2', 3'-cyclic nucleotide 3'-phosphodiesterase (cnpase) but different for myelin oligodendrocyte glycoprotein (mog) in the presence of soluble pdgf-aa vs. immobilized pdgf-aa. |
2009-11-30 |
2023-08-12 |
Not clear |
| Magnus Isaksson, Brita Ardesjö, Lars Rönnblom, Olle Kämpe, Hans Lassmann, Maija-Leena Eloranta, Anna Lobel. Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE. European journal of immunology. vol 39. issue 10. 2009-11-16. PMID:19637225. |
to investigate the role of plasmacytoid dc (pdc) in the initiation of autoimmune th17- and th1-cell responses and eae, we depleted pdc with anti-pdc ag-1 (anti-pdca1) mab prior to immunization of c57bl/6 mice with myelin oligodendrocyte glycoprotein (mog). |
2009-11-16 |
2023-08-12 |
mouse |
| Ian S Zagon, Kristen A Rahn, Anthony P Turel, Patricia J McLaughli. Endogenous opioids regulate expression of experimental autoimmune encephalomyelitis: a new paradigm for the treatment of multiple sclerosis. Experimental biology and medicine (Maywood, N.J.). vol 234. issue 11. 2009-11-10. PMID:19855075. |
a mouse model of myelin oligodendrocyte glycoprotein (mog)-induced eae was employed in conjunction with daily treatment of ldn (0.1 mg/kg, ntx), hdn (10 mg/kg ntx), or vehicle (saline). |
2009-11-10 |
2023-08-12 |
mouse |
| Mir Sajad, Jamil Zargan, Raman Chawla, Sadiq Umar, Mir Sadaqat, Haider A Kha. Hippocampal neurodegeneration in experimental autoimmune encephalomyelitis (EAE): potential role of inflammation activated myeloperoxidase. Molecular and cellular biochemistry. vol 328. issue 1-2. 2009-11-03. PMID:19301098. |
nitric oxide metabolites increased significantly (p < 0.05) with enhancement of mpo (myeloperoxidase activity) (p < 0.001) in the mog (myelin oligodendrocyte protein) group as compared to the controls. |
2009-11-03 |
2023-08-12 |
human |
| Qing Li, Kristine Nacion, Hong Bu, Feng Li. The complement inhibitor FUT-175 suppresses T cell autoreactivity in experimental autoimmune encephalomyelitis. The American journal of pathology. vol 175. issue 2. 2009-10-27. PMID:19608865. |
several recent studies have shown that interacting antigen presenting cells and/or t cells produced complement activation products c5a and c3a, are integrally involved in t-cell activation, and promote the generation of myelin oligodendrocyte glycoprotein (mog(35-55))-specific interferon-gamma and interleukin-17-producing t cells in experimental autoimmune encephalomyelitis, a rodent model of multiple sclerosis. |
2009-10-27 |
2023-08-12 |
mouse |