| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Volker Siffrin, Helena Radbruch, Robert Glumm, Raluca Niesner, Magdalena Paterka, Josephine Herz, Tina Leuenberger, Sabrina M Lehmann, Sarah Luenstedt, Jan Leo Rinnenthal, Gregor Laube, Hervé Luche, Seija Lehnardt, Hans-Joerg Fehling, Oliver Griesbeck, Frauke Zip. In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis. Immunity. vol 33. issue 3. 2010-10-13. PMID:20870176. |
direct interaction of myelin oligodendrocyte glycoprotein (mog)-specific th17 and neuronal cells in demyelinating lesions was associated with extensive axonal damage. |
2010-10-13 |
2023-08-12 |
mouse |
| Koen Venken, Niels Hellings, Karen Hensen, Jean-Luc Rummens, Piet Stinisse. Memory CD4+CD127high T cells from patients with multiple sclerosis produce IL-17 in response to myelin antigens. Journal of neuroimmunology. vol 226. issue 1-2. 2010-10-06. PMID:20554330. |
here, we analyzed the reactivity of peripheral naive and memory conventional cd4(+)cd127(high) t cells (tconv) of ms patients and healthy controls (hc) towards myelin basic protein (mbp), myelin oligodendrocyte glycoprotein (mog) and tetanus toxoid (tt). |
2010-10-06 |
2023-08-12 |
Not clear |
| Itzhak Mendel, Anat Shoham, Oshrat Propheta-Meiran, Eti Ishai, Gideon Halperin, Erez Feige, Eyal Breitbar. A Lecinoxoid, an oxidized phospholipid small molecule, constrains CNS autoimmune disease. Journal of neuroimmunology. vol 226. issue 1-2. 2010-10-06. PMID:20663571. |
oral administration of vb-201 ameliorated the severity of experimental autoimmune encephalomyelitis (eae) induced by myelin oligodendrocyte glycoprotein (mog) peptide mog35-55, and restrained the encephalogenicity of mog35-55-specific t-cells. |
2010-10-06 |
2023-08-12 |
Not clear |
| Eric C Klawiter, Laura Piccio, Jeri-Anne Lyons, Robert Mikesell, Kevin C O'Connor, Anne H Cros. Elevated intrathecal myelin oligodendrocyte glycoprotein antibodies in multiple sclerosis. Archives of neurology. vol 67. issue 9. 2010-10-01. PMID:20837855. |
to evaluate antibodies to myelin oligodendrocyte glycoprotein (mog) in the serum and cerebrospinal fluid (csf) of patients with multiple sclerosis (ms) and control individuals. |
2010-10-01 |
2023-08-12 |
Not clear |
| Tobias V Lanz, Christiane A Opitz, Peggy P Ho, Ankur Agrawal, Christian Lutz, Michael Weller, Andrew L Mellor, Lawrence Steinman, Wolfgang Wick, Michael Platte. Mouse mesenchymal stem cells suppress antigen-specific TH cell immunity independent of indoleamine 2,3-dioxygenase 1 (IDO1). Stem cells and development. vol 19. issue 5. 2010-09-22. PMID:19886804. |
while mmsc suppressed the activation of antigen-specific myelin oligodendrocyte glycoprotein (mog)-reactive t-cell receptor (tcr) transgenic t-helper (th) cells in co-culture, neither pharmacologic inhibition nor genetic ablation of ido1 reversed this suppressive effect. |
2010-09-22 |
2023-08-12 |
mouse |
| Idan S Rakover, Natalia Zabavnik, Rela Kopel, Miri Paz-Rozner, Beka Solomo. Antigen-specific therapy of EAE via intranasal delivery of filamentous phage displaying a myelin immunodominant epitope. Journal of neuroimmunology. vol 225. issue 1-2. 2010-09-16. PMID:20546938. |
here, we present a novel strategy based on filamentous phage display of the myelin oligodendrocyte glycoprotein immunodominant epitope (mog 36-44) fused to the main coat protein. |
2010-09-16 |
2023-08-12 |
mouse |
| R Nohra, A D Beyeen, J P Guo, M Khademi, E Sundqvist, M T Hedreul, F Sellebjerg, C Smestad, A B Oturai, H F Harbo, E Wallström, J Hillert, L Alfredsson, I Kockum, M Jagodic, J Lorentzen, T Olsso. RGMA and IL21R show association with experimental inflammation and multiple sclerosis. Genes and immunity. vol 11. issue 4. 2010-09-03. PMID:20072140. |
we fine-dissected this region that regulated cytokine production, myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae), anti-mog antibodies and pristane-induced arthritis (pia) in advanced intercross lines (ails). |
2010-09-03 |
2023-08-12 |
rat |
| Sushmita Sinha, Sandhya Subramanian, Ashley Emerson-Webber, Maren Lindner, Gregory G Burrows, Marjorie Grafe, Christopher Linington, Arthur A Vandenbark, Claude C A Bernard, Halina Offne. Recombinant TCR ligand reverses clinical signs and CNS damage of EAE induced by recombinant human MOG. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 5. issue 2. 2010-08-03. PMID:19789980. |
increasing evidence suggests that in addition to t cell-dependent effector mechanisms, autoantibodies are also involved in the pathogenesis of ms, including demyelinating antibodies specific for myelin oligodendrocyte glycoprotein (mog). |
2010-08-03 |
2023-08-12 |
mouse |
| Jie-Zhong Yu, Jing Ding, Cun-Gen Ma, Chang-Hai Sun, Yi-Fu Sun, Chuan-Zhen Lu, Bao-Guo Xia. Therapeutic potential of experimental autoimmune encephalomyelitis by Fasudil, a Rho kinase inhibitor. Journal of neuroscience research. vol 88. issue 8. 2010-07-12. PMID:20077431. |
here we further confirm that fasudil, a selective rock inhibitor, has therapeutic potential in a mouse model of myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae). |
2010-07-12 |
2023-08-12 |
mouse |
| Delinda A Johnson, Sara Amirahmadi, Charlotte Ward, Zsuszanna Fabry, Jeffrey A Johnso. The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis. Toxicological sciences : an official journal of the Society of Toxicology. vol 114. issue 2. 2010-06-21. PMID:19910389. |
wild-type (wt) mice and nrf2 knockout mice were immunized with myelin oligodendrocyte glycoprotein (mog 35-55) and monitored daily for clinical scores of disease. |
2010-06-21 |
2023-08-12 |
mouse |
| Hong Zhang, Joseph R Podojil, Judy Chang, Xunrong Luo, Stephen D Mille. TGF-beta-induced myelin peptide-specific regulatory T cells mediate antigen-specific suppression of induction of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 184. issue 12. 2010-06-18. PMID:20483764. |
furthermore, 139-itregs inhibit delayed-type hypersensitivity responses to plp139-151, but not plp178-191, myelin oligodendrocyte glycoprotein (mog)35-55, or ova323-339 in mice primed with a mixture of plp139-151 and the other respective peptides. |
2010-06-18 |
2023-08-12 |
mouse |
| Nathali Kaushansky, Miriam Eisenstein, Rina Zilkha-Falb, Avraham Ben-Nu. The myelin-associated oligodendrocytic basic protein (MOBP) as a relevant primary target autoantigen in multiple sclerosis. Autoimmunity reviews. vol 9. issue 4. 2010-06-14. PMID:19683076. |
here we review studies showing that mobp is as an important candidate target antigen in ms as the other widely studied target antigens, myelin basic protein (mbp), proteolipid protein (plp), and myelin oligodendrocyte glycoprotein (mog). |
2010-06-14 |
2023-08-12 |
mouse |
| J Ockinger, P Stridh, A D Beyeen, F Lundmark, M Seddighzadeh, A Oturai, P S Sørensen, A R Lorentzen, E G Celius, V Leppä, K Koivisto, P J Tienari, L Alfredsson, L Padyukov, J Hillert, I Kockum, M Jagodic, T Olsso. Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis. Genes and immunity. vol 11. issue 2. 2010-06-14. PMID:19865101. |
for the identification of genes regulating neuroinflammation we used a rat model of ms, myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae), and carried out a linkage analysis in an advanced intercross line (ail). |
2010-06-14 |
2023-08-12 |
human |
| Jianmei W Leavenworth, Carola Schellack, Hye-Jung Kim, Linrong Lu, Pieter Spee, Harvey Canto. Analysis of the cellular mechanism underlying inhibition of EAE after treatment with anti-NKG2A F(ab')2. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 6. 2010-05-07. PMID:20133787. |
anti-nkg2a f(ab')(2) treatment diminishes progression of both myelin oligodendrocyte glycoprotein (mog)-induced eae in intact c57bl/6 mice and after adoptive transfer of disease-causing t cells. |
2010-05-07 |
2023-08-12 |
mouse |
| Ian S Zagon, Kristen A Rahn, Robert H Bonneau, Anthony P Turel, Patricia J McLaughli. Opioid growth factor suppresses expression of experimental autoimmune encephalomyelitis. Brain research. vol 1310. 2010-03-30. PMID:19931226. |
c57bl/6 mice injected with myelin oligodendrocyte glycoprotein (mog) received daily injections of 10 mg/kg ogf (mog+ogf) or saline (mog+vehicle). |
2010-03-30 |
2023-08-12 |
mouse |
| M Marta, P Stridh, K Becanovic, A Gillett, J Ockinger, J C Lorentzen, M Jagodic, T Olsso. Multiple loci comprising immune-related genes regulate experimental neuroinflammation. Genes and immunity. vol 11. issue 1. 2010-03-23. PMID:19675581. |
analyses of the humoral immune response revealed that the levels of serum anti-myelin oligodendrocyte glycoprotein (mog) immunoglobin g1 (igg1) antibodies are linked to eae24 and anti-mog igg2b antibodies are linked to both eae24 and eae26. |
2010-03-23 |
2023-08-12 |
rat |
| Muhammet F Gulen, Zizhen Kang, Katarzyna Bulek, Wan Youzhong, Tae Whan Kim, Yi Chen, Cengiz Z Altuntas, Kristian Sass Bak-Jensen, Mandy J McGeachy, Jeong-Su Do, Hui Xiao, Greg M Delgoffe, Booki Min, Jonathan D Powell, Vincent K Tuohy, Daniel J Cua, Xiaoxia L. The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity. vol 32. issue 1. 2010-03-23. PMID:20060329. |
the absence of sigirr in t cells resulted in increased th17 cell polarization in vivo upon myelin oligodendrocyte glycoprotein (mog(35-55)) peptide immunization. |
2010-03-23 |
2023-08-12 |
Not clear |
| Guo Qian Chen, Yan Yan Chen, Xin Shi Wang, Sai Zhen Wu, Hui Min Yang, Hui Qin Xu, Jin Cai He, Xiao Tong Wang, Jiang Fan Chen, Rong Yuan Zhen. Chronic caffeine treatment attenuates experimental autoimmune encephalomyelitis induced by guinea pig spinal cord homogenates in Wistar rats. Brain research. vol 1309. 2010-02-26. PMID:19879252. |
caffeine, a non-selective antagonist of adenosine receptors, has been shown to provide protection against myelin oligodendroglia glycoprotein (mog)-induced eae in mice. |
2010-02-26 |
2023-08-12 |
mouse |
| Mrinalini Kala, Susan N Rhodes, Wen-Hua Piao, Fu-Dong Shi, Denise I Campagnolo, Timothy L Vollme. B cells from glatiramer acetate-treated mice suppress experimental autoimmune encephalomyelitis. Experimental neurology. vol 221. issue 1. 2010-02-16. PMID:19879259. |
b cells from ga-treated mice also diminished proliferation of myelin oligodendrocyte glycoprotein (mog(35-55)) specific t cells. |
2010-02-16 |
2023-08-12 |
mouse |
| K Mangano, A Nicoletti, F Patti, M Donia, L Malaguarnera, S Signorelli, G Magro, V Muzio, B Greco, P Zaratin, P Meroni, M Zappia, F Nicolett. Variable effects of cyclophosphamide in rodent models of experimental allergic encephalomyelitis. Clinical and experimental immunology. vol 159. issue 2. 2010-02-03. PMID:19922500. |
in this study, we have evaluated the effects of cyclophosphamide on the development of experimental allergic encephalomyelitis (eae) in four eae rodent models: monophasic eae in lewis rats, protracted relapsing (pr)-eae in da rats, myelin oligodendrocyte protein (mog)-induced eae in c57bl/6 mice and proteolipid protein (plp)-induced eae in swiss/jackson laboratory (sjl) mice. |
2010-02-03 |
2023-08-12 |
mouse |