| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Milica Jovanović, Ivana Stefanoska, Ljiljana Radojcić, Ljiljana Vićova. Interleukin-8 (CXCL8) stimulates trophoblast cell migration and invasion by increasing levels of matrix metalloproteinase (MMP)2 and MMP9 and integrins alpha5 and beta1. Reproduction (Cambridge, England). vol 139. issue 4. 2010-07-05. PMID:20133364. |
matrix metalloproteinase (mmp)2, mmp9, and integrins alpha(5)beta(1) and alpha(1)beta(1) were found to play important roles in trophoblast invasion. |
2010-07-05 |
2023-08-12 |
Not clear |
| Yong Luo, Fubo Liang, Zhong-Yin Zhan. PRL1 promotes cell migration and invasion by increasing MMP2 and MMP9 expression through Src and ERK1/2 pathways. Biochemistry. vol 48. issue 8. 2010-06-24. PMID:19199380. |
we find that elevated expression of prl1 increases the levels of the matrix metalloproteinases mmp2 and mmp9. |
2010-06-24 |
2023-08-12 |
Not clear |
| Qing-quan Li, Wen-juan Wang, Guo-ping Xu, Xi-xi Cao, Jing-da Xu, Qi Chen, Feng Tang, Zu-de X. [CD147 and matrix metallo-proteinase (MMP) 2 and MMP9 expression in multidrug resistant breast cancer cells treated with P-glycoprotein substrate drugs]. Zhonghua bing li xue za zhi = Chinese journal of pathology. vol 36. issue 4. 2010-06-22. PMID:17706116. |
[cd147 and matrix metallo-proteinase (mmp) 2 and mmp9 expression in multidrug resistant breast cancer cells treated with p-glycoprotein substrate drugs]. |
2010-06-22 |
2023-08-12 |
Not clear |
| Joseph C Chen, Anne A Wiley, Teh-Yuan Ho, Amy-Lynn Frankshun, Kristin M Hord, Frank F Bartol, Carol A Bagnel. Transient estrogen exposure from birth affects uterine expression of developmental markers in neonatal gilts with lasting consequences in pregnant adults. Reproduction (Cambridge, England). vol 139. issue 3. 2010-06-22. PMID:20032211. |
targets included the relaxin receptor (rxfp1), estrogen receptor-alpha (esr1) and vascular endothelial growth factor (vegfa), morphoregulatory markers hoxa10 and wnt7a, and the matrix metalloproteinases (mmp)2 and mmp9. |
2010-06-22 |
2023-08-12 |
Not clear |
| Siyoung Yang, Jonghwan Kim, Je-Hwang Ryu, Hwanhee Oh, Churl-Hong Chun, Byoung Ju Kim, Byoung Hyun Min, Jang-Soo Chu. Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction. Nature medicine. vol 16. issue 6. 2010-06-22. PMID:20495569. |
hif-2alpha directly induces the expression in chondrocytes of genes encoding catabolic factors, including matrix metalloproteinases (mmp1, mmp3, mmp9, mmp12 and mmp13), aggrecanase-1 (adamts4), nitric oxide synthase-2 (nos2) and prostaglandin-endoperoxide synthase-2 (ptgs2). |
2010-06-22 |
2023-08-12 |
mouse |
| Julien H Dey, Fabrizio Bianchi, Johannes Voshol, Debora Bonenfant, Edward J Oakeley, Nancy E Hyne. Targeting fibroblast growth factor receptors blocks PI3K/AKT signaling, induces apoptosis, and impairs mammary tumor outgrowth and metastasis. Cancer research. vol 70. issue 10. 2010-06-21. PMID:20460524. |
of interest are the downregulated matrix metalloproteases (mmp), in particular mmp9, which is essential for metastatic spread of 4t1 tumors. |
2010-06-21 |
2023-08-12 |
mouse |
| C C van Diemen, D S Postma, Y S Aulchenko, P J L M Snijders, B A Oostra, C M van Duijn, H M Boeze. Novel strategy to identify genetic risk factors for COPD severity: a genetic isolate. The European respiratory journal. vol 35. issue 4. 2010-06-18. PMID:19797132. |
in 91 subjects with global initiative for chronic obstructive lung disease (gold) stage >or=1 copd, who were members of an extended pedigree including 6,175 people from the genetic research in isolated populations study, 32 snps were analysed in 13 candidate genes: a disintegrin and metalloprotease domain 33 gene (adam33), transforming growth factor-beta1 gene ( tgfb1), matrix metalloprotease-1 gene (mmp1), mmp2, mmp9, mmp12, tissue inhibitor of metalloprotease-1 gene (timp1), surfactant protein a1 gene (sftpa1 ), sftpa2, sftpb, sftpd, glutathione s-transferase p1 gene (gstp1), and haem oxygenase 1 gene ( hmox1). |
2010-06-18 |
2023-08-12 |
human |
| Susan E Sweeney, Trevor B Kimbler, Gary S Firestei. Synoviocyte innate immune responses: II. Pivotal role of IFN regulatory factor 3. Journal of immunology (Baltimore, Md. : 1950). vol 184. issue 12. 2010-06-18. PMID:20483755. |
surprisingly, irf3 knockdown almost completely blocked expression of additional genes in which the isre is not traditionally considered a dominant promoter site in fibroblast-like synoviocytes, including matrix metalloproteinase (mmp)3, mmp9, il-6, and il-8. |
2010-06-18 |
2023-08-12 |
human |
| Ajanta Chakraborty, Neetu Gupta, Kaushik Ghosh, Partha Ro. In vitro evaluation of the cytotoxic, anti-proliferative and anti-oxidant properties of pterostilbene isolated from Pterocarpus marsupium. Toxicology in vitro : an international journal published in association with BIBRA. vol 24. issue 4. 2010-06-17. PMID:20152895. |
it also inhibited matrix metalloproteinase 9 (mmp9) and alpha-methylacyl-coa recemase (amacr), two very well known metastasis inducers. |
2010-06-17 |
2023-08-12 |
Not clear |
| Mathew Loesch, Hui-Ying Zhi, Song-Wang Hou, Xiao-Mei Qi, Rong-Shan Li, Zainab Basir, Thomas Iftner, Ana Cuenda, Guan Che. p38gamma MAPK cooperates with c-Jun in trans-activating matrix metalloproteinase 9. The Journal of biological chemistry. vol 285. issue 20. 2010-06-14. PMID:20231272. |
here, we show that the transcription factor c-jun is activated by p38gamma mapk, and the activated c-jun then recruits p38gamma as a cofactor into the matrix metalloproteinase 9 (mmp9) promoter to induce its trans-activation and cell invasion. |
2010-06-14 |
2023-08-12 |
human |
| Zhi-ying Feng, Xiang-lan Mo, Chun-Kui Shao, Zu-lan S. [Expressions of matrix metalloproteinase 9 in mucosal natural killer/T cell and mature T cell lymphomas and its relation to Epstein-Barr virus infection]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 27. issue 9. 2010-06-09. PMID:17884772. |
to investigate the expression of matrix metalloproteinase 9 (mmp9) in mucosal natural killer/t cell and mature t cell lymphomas and its relation to epstein-barr virus (ebv) infection. |
2010-06-09 |
2023-08-12 |
Not clear |
| Kalyan C Nannuru, Mitsuru Futakuchi, Michelle L Varney, Thomas M Vincent, Eric G Marcusson, Rakesh K Sing. Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface. Cancer research. vol 70. issue 9. 2010-05-27. PMID:20406980. |
matrix metalloproteinase (mmp)-13 regulates mammary tumor-induced osteolysis by activating mmp9 and transforming growth factor-beta signaling at the tumor-bone interface. |
2010-05-27 |
2023-08-12 |
mouse |
| Qi-dong Tang, Ping-sheng Wu, Yu-qing Hou, Zheng Huang, Zhong-jiang Zhou, Zhi-gang Guo, Jian-cheng Xiu, Yue-gang Wan. [Plasma matrix metalloproteinases-2 and -9 levels are elevated in patients with acute coronary syndrome and coronary chronic total occlusion]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 29. issue 5. 2010-05-04. PMID:19460733. |
to investigate the changes in plasma matrix metalloproteinases-2 and -9 (mmp2 and mmp9, respectively) levels in patients with different types of coronary heart diseases (chd), and assess the value of mmp2/mmp9 detection in predicting acute coronary syndrome (acs). |
2010-05-04 |
2023-08-12 |
Not clear |
| B Wang, S-H Hsu, S Majumder, H Kutay, W Huang, S T Jacob, K Ghosha. TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene. vol 29. issue 12. 2010-04-23. PMID:20023698. |
ectopic expression and depletion of mir-181b showed that mir-181b enhanced matrix metallopeptidases (mmp)2 and mmp9 activity and promoted growth, clonogenic survival, migration and invasion of hepatocellular carcinoma (hcc) cells that could be reversed by modulating timp3 level. |
2010-04-23 |
2023-08-12 |
mouse |
| Mirko Moreno Zaldivar, Katrin Pauels, Philipp von Hundelshausen, Marie-Luise Berres, Petra Schmitz, Jörg Bornemann, M Anna Kowalska, Nikolaus Gassler, Konrad L Streetz, Ralf Weiskirchen, Christian Trautwein, Christian Weber, Hermann E Wasmut. CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis. Hepatology (Baltimore, Md.). vol 51. issue 4. 2010-04-21. PMID:20162727. |
accordingly, genetic deletion of cxcl4 in mice significantly reduced histological and biochemical liver damage in vivo, which was accompanied by changes in the expression of fibrosis-related genes (timp-1 [tissue inhibitor of matrix metalloproteinase 1], mmp9 [matrix metalloproteinase 9], tgf-beta [transforming growth factor beta], il10 [interleukin 10]). |
2010-04-21 |
2023-08-12 |
mouse |
| Morris Schweitzer, Benjamin Mitmaker, Daniel Obrand, Nathan Sheiner, Cherrie Abraham, Stevan Dostanic, Melissa Meilleur, Tomoko Sugahara, Lorraine E Chalifou. Atorvastatin modulates matrix metalloproteinase expression, activity, and signaling in abdominal aortic aneurysms. Vascular and endovascular surgery. vol 44. issue 2. 2010-04-01. PMID:20034937. |
matrix metalloproteinase 1, mmp2, mmp3, mmp9, tissue inhibitor of metalloproteinase (timp2), timp3, timp4, or total sma mothers against decapentaplegia (smad2) expression did not differ with treatment. |
2010-04-01 |
2023-08-12 |
human |
| Fei Han, Hong-Guang Zh. Caveolin-1 regulating the invasion and expression of matrix metalloproteinase (MMPs) in pancreatic carcinoma cells. The Journal of surgical research. vol 159. issue 1. 2010-03-23. PMID:20031158. |
the gelatinases b (mmp9) and a (mmp2) are two members of the matrix metalloproteinase (mmps) family that are expressed in human cancer, and play a critical role in tumor cell invasion and metastasis. |
2010-03-23 |
2023-08-12 |
human |
| Camila F Nascimento, Letícia N Gama-De-Souza, Vanessa M Freitas, Ruy G Jaege. Role of MMP9 on invadopodia formation in cells from adenoid cystic carcinoma. Study by laser scanning confocal microscopy. Microscopy research and technique. vol 73. issue 2. 2010-03-17. PMID:19658178. |
after 1 h in fluorescent substrate, cells with silenced mmp9 showed clear decrease in matrix digestion compared with controls. |
2010-03-17 |
2023-08-12 |
human |
| Zhi-jie He, Zi-tong Huang, Xiao-tong Chen, Zi-jun Zo. Effects of matrix metalloproteinase 9 inhibition on the blood brain barrier and inflammation in rats following cardiopulmonary resuscitation. Chinese medical journal. vol 122. issue 19. 2010-03-17. PMID:20079138. |
matrix metalloproteinases (mmps), especially mmp9 attracted much attention because of its function in focal brain ischemia/reperfusion injury. |
2010-03-17 |
2023-08-12 |
rat |
| Geraldine Gueron, Adriana De Siervi, Mercedes Ferrando, Marcelo Salierno, Paola De Luca, Belen Elguero, Roberto Meiss, Nora Navone, Elba S Vazque. Critical role of endogenous heme oxygenase 1 as a tuner of the invasive potential of prostate cancer cells. Molecular cancer research : MCR. vol 7. issue 11. 2010-03-04. PMID:19903769. |
using reverse transcription-quantitative pcr-generated gene array, a set of inflammatory and angiogenic genes were upregulated or downregulated in response to ho-1 overexpression identifying matrix metalloprotease 9 (mmp9) as a novel downstream target of ho-1. |
2010-03-04 |
2023-08-12 |
mouse |