| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu Chen, Xufeng Wei, Changcun Guo, Haifeng Jin, Zheyi Han, Ying Han, Taidong Qiao, Kaichun Wu, Daiming Fa. Runx3 suppresses gastric cancer metastasis through inactivation of MMP9 by upregulation of TIMP-1. International journal of cancer. vol 129. issue 7. 2011-09-20. PMID:21128246. |
gelatin zymography and western blot showed that instead of regulating matrix metalloproteinase 9 (mmp9) expression, runx3 expression inhibited mmp9 enzyme activity, and this was consistent with the upregulation of tissue inhibitor of metalloproteinases 1 (timp1) by runx3. |
2011-09-20 |
2023-08-12 |
Not clear |
| Markus Meissner, Barbara Berlinski, Monika Doll, Igor Hrgovic, Vesselina Laubach, Gabi Reichenbach, Stefan Kippenberger, Jens Gille, Roland Kaufman. AP1-dependent repression of TGFα-mediated MMP9 upregulation by PPARδ agonists in keratinocytes. Experimental dermatology. vol 20. issue 5. 2011-09-16. PMID:21496113. |
matrix metalloproteinase 9 (mmp9) belongs to the set of genes that are effectively induced by tgfα in keratinocytes. |
2011-09-16 |
2023-08-12 |
human |
| Andrea G S Buggins, Ana Levi, Satyen Gohil, Keith Fishlock, Piers E M Patten, Yolanda Calle, Deborah Yallop, Stephen Devereu. Evidence for a macromolecular complex in poor prognosis CLL that contains CD38, CD49d, CD44 and MMP-9. British journal of haematology. vol 154. issue 2. 2011-09-16. PMID:21569005. |
progressive chronic lymphocytic leukaemia is characterized by the accumulation of neoplastic b-cells in the tissues and correlates with the expression of prognostic biomarkers, such as cd38, cd49d and matrix metalloproteinase-9 (mmp9), which are involved in migration and tissue invasion. |
2011-09-16 |
2023-08-12 |
Not clear |
| Dahui Sun, Xu Wang, Haixia Zhang, Lijuan Deng, Yan Zhan. MMP9 mediates MICA shedding in human osteosarcomas. Cell biology international. vol 35. issue 6. 2011-09-02. PMID:21143201. |
a mmp9 (matrix metalloproteinase 9, gelatinase b)-specific inhibitor suppressed smica release, indicating that mmp9 is critically involved in the osteosarcoma-associated proteolytic release of smica, which facilitates tumour immune escape. |
2011-09-02 |
2023-08-12 |
human |
| Stephanie N Zimmer, Qing Zhou, Ting Zhou, Ziming Cheng, Sherry L Abboud-Werner, Diane Horn, Mike Lecocke, Ruth White, Andrei V Krivtsov, Scott A Armstrong, Andrew L Kung, David M Livingston, Vivienne I Rebe. Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis. Blood. vol 118. issue 1. 2011-09-01. PMID:21555743. |
at the molecular level, we found that the known hematopoietic modulators matrix metallopeptidase-9 (mmp9) and kit ligand (kitl) were decreased with heterozygous levels of crebbp. |
2011-09-01 |
2023-08-12 |
mouse |
| Henrik Devitt Møller, Ulrik Ralfkjær, Natascha Cremers, Mika Frankel, Rune Troelsgaard Pedersen, Jörg Klingelhöfer, Hiromi Yanagisawa, Mariam Grigorian, Per Guldberg, Jonathan Sleeman, Eugene Lukanidin, Noona Ambartsumia. Role of fibulin-5 in metastatic organ colonization. Molecular cancer research : MCR. vol 9. issue 5. 2011-08-30. PMID:21454378. |
additional studies suggest a mechanism in which fibulin-5 suppresses metastasis formation by inhibiting production of matrix metalloproteinase 9 (mmp9) and reducing the invasive behavior of fibroblasts. |
2011-08-30 |
2023-08-12 |
Not clear |
| Giuseppina Basini, Simona Bussolati, Laura Baioni, Francesca Grassell. Gelatinases (MMP2 and MMP9) in swine antral follicle. BioFactors (Oxford, England). vol 37. issue 2. 2011-08-30. PMID:21488134. |
since matrix metalloproteinases (mmps) play a crucial role in both of these processes, the aim of the present study was to evaluate the expression of gelatinases mmp2 and mmp9 in swine ovarian follicle (theca and granulosa compartments) during its development. |
2011-08-30 |
2023-08-12 |
Not clear |
| Joseph C Chen, Amy-Lynn Frankshun, Anne A Wiley, Dori J Miller, Kristene A Welch, Teh-Yuan Ho, Frank F Bartol, Carol A Bagnel. Milk-borne lactocrine-acting factors affect gene expression patterns in the developing neonatal porcine uterus. Reproduction (Cambridge, England). vol 141. issue 5. 2011-08-26. PMID:21317299. |
however, colostrum consumption was required for normal uterine esr1, vascular endothelial growth factor (vegfa), matrix metalloproteinase 9 (mmp9), and rlx receptor (rxfp1) protein and/or transcript expression on pnd 2. |
2011-08-26 |
2023-08-12 |
Not clear |
| Jeong-Soo Hong, Kendra J Greenlee, Ramanan Pitchumani, Seung-Hyo Lee, Li-zhen Song, Ming Shan, Seon Hee Chang, Pyong Woo Park, Chen Dong, Zena Werb, Akhil Bidani, David B Corry, Farrah Kheradman. Dual protective mechanisms of matrix metalloproteinases 2 and 9 in immune defense against Streptococcus pneumoniae. Journal of immunology (Baltimore, Md. : 1950). vol 186. issue 11. 2011-08-11. PMID:21508260. |
in an acute model of streptococcus pneumoniae lung infection, deficiency in matrix metalloproteinase (mmp)2 and mmp9 (mmp2/9(-/-)) conferred a survival disadvantage relative to wild-type mice treated under the same conditions. |
2011-08-11 |
2023-08-12 |
mouse |
| Bor-Show Tzang, Tsung-Ming Lin, Chun-Chou Tsai, Jeng-Dong Hsu, Lien-Chuan Yang, Tsai-Ching Hs. Increased cardiac injury in NZB/W F1 mice received antibody against human parvovirus B19 VP1 unique region protein. Molecular immunology. vol 48. issue 12-13. 2011-08-10. PMID:21555155. |
additionally, significant increases of matrix metalloproteinase-9 (mmp9) activity and protein expression were detected in left ventricle of hearts from nzb/w f1 mice receiving b19-vp1u igg. |
2011-08-10 |
2023-08-12 |
mouse |
| Brian M Mercer, Adli Abdelrahim, Robert M Moore, Jillian Novak, Deepak Kumar, Joseph M Mansour, Marina Perez-Fournier, Cynthia J Milluzzi, John J Moor. The impact of vitamin C supplementation in pregnancy and in vitro upon fetal membrane strength and remodeling. Reproductive sciences (Thousand Oaks, Calif.). vol 17. issue 7. 2011-08-08. PMID:20581351. |
supplemental dietary vitamin c in combination with vitamin e did not modify rupture strength, work to rupture, or matrix metalloproteinase-9 (mmp9; protein or activity) either within or outside the term fm physiological weak zone. |
2011-08-08 |
2023-08-12 |
Not clear |
| Jianying Luo, Fuyuan Qiao, Xianghua Yi. Hypoxia induces FGF2 production by vascular endothelial cells and alters MMP9 and TIMP1 expression in extravillous trophoblasts and their invasiveness in a cocultured model. The Journal of reproduction and development. vol 57. issue 1. 2011-08-04. PMID:21041986. |
fgf2 expression in huve-12 cells and matrix metalloproteinase 9 (mmp9) and tissue inhibitor of metalloproteinase 1 (timp1) expression in tev-1 cells were analyzed using quantitative rt-pcr and western blot analyses. |
2011-08-04 |
2023-08-12 |
human |
| Juliane I Beier, J Phillip Kaiser, Luping Guo, Manuel Martínez-Maldonado, Gavin E Artee. Plasminogen activator inhibitor-1 deficient mice are protected from angiotensin II-induced fibrosis. Archives of biochemistry and biophysics. vol 510. issue 1. 2011-07-25. PMID:21501583. |
protection in the knockout strain correlated with a blunted increase in αsma, and elevated activities of matrix metalloproteinases (mmp2, mmp9). |
2011-07-25 |
2023-08-12 |
mouse |
| Xiu-lan Zhao, Tao Sun, Na Che, Dan Sun, Nan Zhao, Xue-yi Dong, Qiang Gu, Zhi Yao, Bao-cun Su. Promotion of hepatocellular carcinoma metastasis through matrix metalloproteinase activation by epithelial-mesenchymal transition regulator Twist1. Journal of cellular and molecular medicine. vol 15. issue 3. 2011-07-22. PMID:20219012. |
by ectopic transfection of twist1 and twist2 into the hcc cells, hepg2 and plc, twist1 is able to down-regulate e-cadherin expression and promote matrix metalloproteinase (mmp) activation, specifically in mmp2 and mmp9. |
2011-07-22 |
2023-08-12 |
human |
| Hideya Onishi, Masaya Kai, Seiichi Odate, Hironori Iwasaki, Yoshihiro Morifuji, Toshitatsu Ogino, Takafumi Morisaki, Yutaka Nakashima, Mitsuo Katan. Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer. Cancer science. vol 102. issue 6. 2011-07-20. PMID:21338440. |
hypoxia upregulated the transcription of sonic hedgehog (shh), smoothened (smo), gli1 and matrix metalloproteinase9 (mmp9) and increased the invasiveness of pdac. |
2011-07-20 |
2023-08-12 |
human |
| Julia S Pettersen, Judilyn Fuentes-Duculan, Mayte Suárez-Fariñas, Katherine C Pierson, Alexander Pitts-Kiefer, Linda Fan, Daniel A Belkin, Claire Q F Wang, Shivaprasad Bhuvanendran, Leanne M Johnson-Huang, Mark J Bluth, James G Krueger, Michelle A Lowes, John A Carucc. Tumor-associated macrophages in the cutaneous SCC microenvironment are heterogeneously activated. The Journal of investigative dermatology. vol 131. issue 6. 2011-07-19. PMID:21307877. |
cd163(+) tams produced protumoral factors, matrix metalloproteinases 9 and 11 (mmp9 and mmp11), at the gene and protein levels. |
2011-07-19 |
2023-08-12 |
human |
| Janusz K Rybakowsk. Matrix Metalloproteinase-9 (MMP9)-A Mediating Enzyme in Cardiovascular Disease, Cancer, and Neuropsychiatric Disorders. Cardiovascular psychiatry and neurology. vol 2009. 2011-07-14. PMID:20037727. |
matrix metalloproteinase-9 (mmp9)-a mediating enzyme in cardiovascular disease, cancer, and neuropsychiatric disorders. |
2011-07-14 |
2023-08-12 |
Not clear |
| Janusz K Rybakowsk. Matrix Metalloproteinase-9 (MMP9)-A Mediating Enzyme in Cardiovascular Disease, Cancer, and Neuropsychiatric Disorders. Cardiovascular psychiatry and neurology. vol 2009. 2011-07-14. PMID:20037727. |
matrix metalloproteinase-9 (mmp9) has been implicated in numerous somatic illnesses, including cardiovascular disorders and cancer. |
2011-07-14 |
2023-08-12 |
Not clear |
| Dipak Sapkota, Ove Bruland, Daniela Elena Costea, Hallvard Haugen, Endre N Vasstrand, Salah O Ibrahi. S100A14 regulates the invasive potential of oral squamous cell carcinoma derived cell-lines in vitro by modulating expression of matrix metalloproteinases, MMP1 and MMP9. European journal of cancer (Oxford, England : 1990). vol 47. issue 4. 2011-07-14. PMID:21074410. |
s100a14 regulates the invasive potential of oral squamous cell carcinoma derived cell-lines in vitro by modulating expression of matrix metalloproteinases, mmp1 and mmp9. |
2011-07-14 |
2023-08-12 |
human |
| Arpit Tandon, Siddharth Sinh. Structural insights into the binding of MMP9 inhibitors. Bioinformation. vol 5. issue 8. 2011-07-14. PMID:21383916. |
mmp9 (gelatinase b) is one of the common matrix metalloproteinase that is associated with tissue destruction in a number of disease states such as rheumatoid arthiritis, fibrotic lung disease, dilated cardiomyopathy, as well as cancer invasion and metastasis. |
2011-07-14 |
2023-08-12 |
Not clear |