All Relations between microtubule-associated protein tau and hippocampus

Publication Sentence Publish Date Extraction Date Species
Shu Yang, Qihai Gong, Qin Wu, Fei Li, Yuanfu Lu, Jingshan Sh. Alkaloids enriched extract from Dendrobium nobile Lindl. attenuates tau protein hyperphosphorylation and apoptosis induced by lipopolysaccharide in rat brain. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 21. issue 5. 2014-12-15. PMID:24268296. the present study demonstrated that ednla attenuates lps-induced hyperphosphorylation of tau protein in rat's hippocampus and protects against lps-induced apoptosis in rat brain. 2014-12-15 2023-08-12 rat
Tomohiro Onishi, Yoshio Matsumoto, Masahiko Hattori, Yuka Obayashi, Kimie Nakamura, Takashi Yano, Takashi Horiguchi, Hiroki Iwashit. Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice. Neuroscience research. vol 80. 2014-12-04. PMID:24406748. tau phosphorylation in the hippocampus of tpr50 mice increased with age, particularly at s202/t205. 2014-12-04 2023-08-12 mouse
Tomohiro Onishi, Yoshio Matsumoto, Masahiko Hattori, Yuka Obayashi, Kimie Nakamura, Takashi Yano, Takashi Horiguchi, Hiroki Iwashit. Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice. Neuroscience research. vol 80. 2014-12-04. PMID:24406748. insolubilization and intracellular accumulation of tau were detected in the hippocampus by 9 months of age. 2014-12-04 2023-08-12 mouse
Tomohiro Onishi, Yoshio Matsumoto, Masahiko Hattori, Yuka Obayashi, Kimie Nakamura, Takashi Yano, Takashi Horiguchi, Hiroki Iwashit. Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice. Neuroscience research. vol 80. 2014-12-04. PMID:24406748. at this age or earlier, although no intracellular tau accumulation was observed in the hippocampus, abnormally increased microtubule (mt)-related proteins and mt hyperdynamics in the hippocampus, and impaired axonal transport in the septo-hippocampal pathway were already observed. 2014-12-04 2023-08-12 mouse
Fangli Liu, Zhenfei Xue, Ning Li, Hui Huang, Yanyan Ying, Jin Li, Lin Wang, Wenjie L. Effects of lead exposure on the expression of amyloid β and phosphorylated tau proteins in the C57BL/6 mouse hippocampus at different life stages. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 28. issue 2. 2014-12-03. PMID:24582137. effects of lead exposure on the expression of amyloid β and phosphorylated tau proteins in the c57bl/6 mouse hippocampus at different life stages. 2014-12-03 2023-08-12 mouse
Fangli Liu, Zhenfei Xue, Ning Li, Hui Huang, Yanyan Ying, Jin Li, Lin Wang, Wenjie L. Effects of lead exposure on the expression of amyloid β and phosphorylated tau proteins in the C57BL/6 mouse hippocampus at different life stages. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 28. issue 2. 2014-12-03. PMID:24582137. the objective of this study was to investigate the effects of lead exposure on spatial learning and memory capacity and the expression of amyloid β and phosphorylated tau proteins in the mouse hippocampus. 2014-12-03 2023-08-12 mouse
Fangli Liu, Zhenfei Xue, Ning Li, Hui Huang, Yanyan Ying, Jin Li, Lin Wang, Wenjie L. Effects of lead exposure on the expression of amyloid β and phosphorylated tau proteins in the C57BL/6 mouse hippocampus at different life stages. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 28. issue 2. 2014-12-03. PMID:24582137. the protein expression of amyloid β and phosphorylated tau in the hippocampus was detected via western blot. 2014-12-03 2023-08-12 mouse
Shunsuke Koga, Ayako Kojima, Satoshi Kuwabara, Yasumasa Yoshiyam. Immunohistochemical analysis of tau phosphorylation and astroglial activation with enhanced leptin receptor expression in diet-induced obesity mouse hippocampus. Neuroscience letters. vol 571. 2014-12-03. PMID:24785100. immunohistochemical analysis of tau phosphorylation and astroglial activation with enhanced leptin receptor expression in diet-induced obesity mouse hippocampus. 2014-12-03 2023-08-13 mouse
Shunsuke Koga, Ayako Kojima, Satoshi Kuwabara, Yasumasa Yoshiyam. Immunohistochemical analysis of tau phosphorylation and astroglial activation with enhanced leptin receptor expression in diet-induced obesity mouse hippocampus. Neuroscience letters. vol 571. 2014-12-03. PMID:24785100. dio caused tau phosphorylation and astroglial activation in the hippocampus in wt mice. 2014-12-03 2023-08-13 mouse
Shunsuke Koga, Ayako Kojima, Satoshi Kuwabara, Yasumasa Yoshiyam. Immunohistochemical analysis of tau phosphorylation and astroglial activation with enhanced leptin receptor expression in diet-induced obesity mouse hippocampus. Neuroscience letters. vol 571. 2014-12-03. PMID:24785100. although phosphorylated tau staining was only observed in the hippocampus, astrogliosis and microgliosis were present in both the amygdala and hippocampus. 2014-12-03 2023-08-13 mouse
Shunsuke Koga, Ayako Kojima, Satoshi Kuwabara, Yasumasa Yoshiyam. Immunohistochemical analysis of tau phosphorylation and astroglial activation with enhanced leptin receptor expression in diet-induced obesity mouse hippocampus. Neuroscience letters. vol 571. 2014-12-03. PMID:24785100. our results demonstrate for the first time that dio causes tau phosphorylation and that astrocytic lepr might be involved in the pathological process in wt mouse hippocampus. 2014-12-03 2023-08-13 mouse
Yun Zhang, Liyun Chen, Guangli Shen, Qian Zhao, Lijuan Shangguan, Maolin H. GRK5 dysfunction accelerates tau hyperphosphorylation in APP (swe) mice through impaired cholinergic activity. Neuroreport. vol 25. issue 7. 2014-11-28. PMID:24598771. grk dysfunction also promotes a deleterious cycle that further increases β-amyloid accumulation and exaggerates tau hyperphosphorylation in the hippocampus. 2014-11-28 2023-08-12 mouse
Yun Zhang, Liyun Chen, Guangli Shen, Qian Zhao, Lijuan Shangguan, Maolin H. GRK5 dysfunction accelerates tau hyperphosphorylation in APP (swe) mice through impaired cholinergic activity. Neuroreport. vol 25. issue 7. 2014-11-28. PMID:24598771. moreover, treatment with methoctramine, a selective m2 antagonist, partially corrected the difference between wild-type control mice and grk5-dysfunctional app (swe) mice in hippocampal ach release, pkc and gsk3β activities, as well as tau hyperphosphorylation. 2014-11-28 2023-08-12 mouse
Kristyn Bates, Robert Vink, Ralph Martins, Alan Harve. Aging, cortical injury and Alzheimer's disease-like pathology in the guinea pig brain. Neurobiology of aging. vol 35. issue 6. 2014-11-25. PMID:24360504. diffuse deposits of aβ were found in the hippocampal region of the oldest animals and alterations in amyloid precursor protein processing and tau immunoreactivity were observed with age. 2014-11-25 2023-08-12 human
T L Briones, H Darwis. Decrease in age-related tau hyperphosphorylation and cognitive improvement following vitamin D supplementation are associated with modulation of brain energy metabolism and redox state. Neuroscience. vol 262. 2014-11-24. PMID:24412233. tau phosphorylation, markers of brain energy metabolism (adp/atp ratio and adenosine monophosphate-activated protein kinase) and redox state (levels of reactive oxygen species, activity of superoxide dismutase, and glutathione levels) as well as pp2a activity were measured in hippocampal tissues. 2014-11-24 2023-08-12 rat
Lai-Ling Du, Jia-Zhao Xie, Xiang-Shu Cheng, Xiao-Hong Li, Fan-Li Kong, Xia Jiang, Zhi-Wei Ma, Jian-Zhi Wang, Chen Chen, Xin-Wen Zho. Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi. Age (Dordrecht, Netherlands). vol 36. issue 2. 2014-11-18. PMID:24142524. in conclusion, sirt1 protects hippocampus neurons from tau hyperphosphorylation and prevents cognitive impairment induced by icv-stz brain insulin resistance with decreased hippocampus erk1/2 activity. 2014-11-18 2023-08-12 rat
Huda S Darusman, Jacub Pandelaki, Rahmad Mulyadi, Dondin Sajuthi, Indah A Putri, Otto H Kalliokoski, Josep Call, Klas S P Abelson, Steven J Schapiro, Albert Gjedde, Jann Ha. Poor memory performance in aged cynomolgus monkeys with hippocampal atrophy, depletion of amyloid beta 1-42 and accumulation of tau proteins in cerebrospinal fluid. In vivo (Athens, Greece). vol 28. issue 2. 2014-11-06. PMID:24632970. poor memory performance in aged cynomolgus monkeys with hippocampal atrophy, depletion of amyloid beta 1-42 and accumulation of tau proteins in cerebrospinal fluid. 2014-11-06 2023-08-12 monkey
Pamela Salcedo-Tello, Karina Hernández-Ortega, Clorinda Aria. Susceptibility to GSK3β-induced tau phosphorylation differs between the young and aged hippocampus after Wnt signaling inhibition. Journal of Alzheimer's disease : JAD. vol 39. issue 4. 2014-10-30. PMID:24270208. susceptibility to gsk3β-induced tau phosphorylation differs between the young and aged hippocampus after wnt signaling inhibition. 2014-10-30 2023-08-12 rat
Pamela Salcedo-Tello, Karina Hernández-Ortega, Clorinda Aria. Susceptibility to GSK3β-induced tau phosphorylation differs between the young and aged hippocampus after Wnt signaling inhibition. Journal of Alzheimer's disease : JAD. vol 39. issue 4. 2014-10-30. PMID:24270208. here, we report that the wnt antagonist dkk-1 selectively increases tau phosphorylation in the hippocampus of aged rats at ser199/202, ser396/404, and ser214 sites. 2014-10-30 2023-08-12 rat
Mar Pérez, Raquel Cuadros, Noemi Pallas-Bazarra, Carlos García, Elena Langa, Jerónimo Jurado-Arjona, Félix Hernández, Jesús Avil. Boronate-tau mediated uptake in neurons. Journal of Alzheimer's disease : JAD. vol 40. issue 1. 2014-10-30. PMID:24366920. our results indicate that the incorporated tau promotes the formation of cytoplasmic extensions in non-neuronal cells, as well as the appearance of neurites in cultured tau knockout hippocampal neurons. 2014-10-30 2023-08-12 mouse