All Relations between microtubule-associated protein tau and hippocampus

Publication Sentence Publish Date Extraction Date Species
Meifeng Yang, Jing Lu, Junye Miao, Joshua Rizak, Jianzhen Yang, Rongwei Zhai, Jun Zhou, Jiagui Qu, Jianhong Wang, Shangchuan Yang, Yuanye Ma, Xintian Hu, Rongqiao H. Alzheimer's disease and methanol toxicity (part 1): chronic methanol feeding led to memory impairments and tau hyperphosphorylation in mice. Journal of Alzheimer's disease : JAD. vol 41. issue 4. 2015-03-30. PMID:24787915. the in vitro experiments suggested that formaldehyde was most likely the detrimental component of methanol toxicity related to hippocampal tau phosphorylation and the subsequent impaired memory in the mice. 2015-03-30 2023-08-13 mouse
Meifeng Yang, Junye Miao, Joshua Rizak, Rongwei Zhai, Zhengbo Wang, Tanzeel Huma, Ting Li, Na Zheng, Shihao Wu, Yingwei Zheng, Xiaona Fan, Jianzhen Yang, Jianhong Wang, Shangchuan Yang, Yuanye Ma, Longbao Lü, Rongqiao He, Xintian H. Alzheimer's disease and methanol toxicity (part 2): lessons from four rhesus macaques (Macaca mulatta) chronically fed methanol. Journal of Alzheimer's disease : JAD. vol 41. issue 4. 2015-03-30. PMID:24787917. this change coincided with increases in tau protein phosphorylation at residues t181 and s396 in cerebrospinal fluid during feeding as well as with increases in tau phosphorylated aggregates and amyloid plaques in four brain regions postmortem: the frontal lobe, parietal lobe, temporal lobe, and the hippocampus. 2015-03-30 2023-08-13 mouse
Li Lin, Shu-Sheng Yang, Jiang Chu, Lu Wang, Lin-Na Ning, Teng Zhang, Qian Jiang, Qing Tian, Jian-Zhi Wan. Region-specific expression of tau, amyloid-β protein precursor, and synaptic proteins at physiological condition or under endoplasmic reticulum stress in rats. Journal of Alzheimer's disease : JAD. vol 41. issue 4. 2015-03-30. PMID:24787918. simultaneously, levels of phosphorylated tau at all of the above sites were significantly increased with the activation of glycogen synthase kinase-3β in temporal cortex, frontal cortex, and/or hippocampus, but not cerebellum. 2015-03-30 2023-08-13 rat
Holly C Hunsberger, Carolyn C Rudy, Seth R Batten, Greg A Gerhardt, Miranda N Ree. P301L tau expression affects glutamate release and clearance in the hippocampal trisynaptic pathway. Journal of neurochemistry. vol 132. issue 2. 2015-03-16. PMID:25319522. p301l tau expression affects glutamate release and clearance in the hippocampal trisynaptic pathway. 2015-03-16 2023-08-13 mouse
Holly C Hunsberger, Carolyn C Rudy, Seth R Batten, Greg A Gerhardt, Miranda N Ree. P301L tau expression affects glutamate release and clearance in the hippocampal trisynaptic pathway. Journal of neurochemistry. vol 132. issue 2. 2015-03-16. PMID:25319522. here, we used a tau mouse model of ad (rtg(taup301l)4510) to examine the effects of tau pathology on hippocampal glutamate regulation. 2015-03-16 2023-08-13 mouse
b' Andrea \\xc5\\xa0polcov\\xc3\\xa1, Barbora Mikul\\xc3\\xa1\\xc5\\xa1kov\\xc3\\xa1, Katar\\xc3\\xadna Kr\\xc5\\xa1kov\\xc3\\xa1, Lucia Gajdo\\xc5\\xa1echov\\xc3\\xa1, \\xc5\\xa0tefan Z\\xc3\\xb3rad, Rafa\\xc5\\x82 Olszanecki, Maciej Suski, Beata Bujak-Gi\\xc5\\xbcycka, Blanka \\xc5\\xbdelezn\\xc3\\xa1, Lenka Malet\\xc3\\xadnsk\\xc3\\xa. Deficient hippocampal insulin signaling and augmented Tau phosphorylation is related to obesity- and age-induced peripheral insulin resistance: a study in Zucker rats. BMC neuroscience. vol 15. 2015-03-12. PMID:25257559.' deficient hippocampal insulin signaling and augmented tau phosphorylation is related to obesity- and age-induced peripheral insulin resistance: a study in zucker rats. 2015-03-12 2023-08-13 rat
Cyril Laurent, Sabiha Eddarkaoui, Maxime Derisbourg, Antoine Leboucher, Dominique Demeyer, Sébastien Carrier, Marion Schneider, Malika Hamdane, Christa E Müller, Luc Buée, David Blu. Beneficial effects of caffeine in a transgenic model of Alzheimer's disease-like tau pathology. Neurobiology of aging. vol 35. issue 9. 2015-02-12. PMID:24780254. improved memory was associated with reduced hippocampal tau phosphorylation and proteolytic fragments. 2015-02-12 2023-08-13 mouse
Sarah A L Martin, Christine H Jameson, Stuart M Allan, Catherine B Lawrenc. Maternal high-fat diet worsens memory deficits in the triple-transgenic (3xTgAD) mouse model of Alzheimer's disease. PloS one. vol 9. issue 6. 2015-02-02. PMID:24918775. these effects of a maternal high-fat diet on memory were accompanied by a significant increase (50%) in the number of tau positive neurones in the hippocampus. 2015-02-02 2023-08-13 mouse
Guoli Song, Zhonghao Zhang, Lei Wen, Chen Chen, Qingxue Shi, Yu Zhang, Jiazuan Ni, Qiong Li. Selenomethionine ameliorates cognitive decline, reduces tau hyperphosphorylation, and reverses synaptic deficit in the triple transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 41. issue 1. 2015-01-29. PMID:24577479. se-met treatment significantly reduced the level of total tau and phosphorylated tau, mitigated the decrease of synaptic proteins including synaptophysin and postsynaptic density protein 95 in the hippocampus and cortex of the 3 × tg-ad mice. 2015-01-29 2023-08-12 mouse
E Orta-Salazar, A Aguilar-Vázquez, H Martínez-Coria, S Luquín-De Anda, M Rivera-Cervantes, C Beas-Zarate, A Feria-Velasco, S Díaz-Cintr. REST/NRSF-induced changes of ChAT protein expression in the neocortex and hippocampus of the 3xTg-AD mouse model for Alzheimer's disease. Life sciences. vol 116. issue 2. 2015-01-28. PMID:25261598. the objective of this work was to determine the rest/nrsf involvement in altered chat expression in the neocortex and hippocampus of an ad transgenic mouse (homozygous 3xtg-ad) that over-expresses 3 proteins, amyloid-β precursor protein, presenilin-1, and tau, all of which are associated with ad and cause cellular degeneration. 2015-01-28 2023-08-13 mouse
Wenqing Yang, Jing Ma, Zheng Liu, Yongliang Lu, Bin Hu, Huarong Y. Effect of naringenin on brain insulin signaling and cognitive functions in ICV-STZ induced dementia model of rats. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 35. issue 5. 2015-01-27. PMID:24337945. in addition, nar reversed icv-stz induced tau hyper-phosphorylation in both hippocampus and cerebral cortex through downregulation of glycogen synthase kinase-3β (gsk-3β) activity, a key kinase in the insulin signaling. 2015-01-27 2023-08-12 rat
Li-Feng Zhang, Lv Shi, Hui Liu, Fan-Tao Meng, Ya-Jing Liu, Hui-Mei Wu, Xin Du, Jiang-Ning Zho. Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21418733. increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress. 2015-01-22 2023-08-12 mouse
Li-Feng Zhang, Lv Shi, Hui Liu, Fan-Tao Meng, Ya-Jing Liu, Hui-Mei Wu, Xin Du, Jiang-Ning Zho. Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21418733. the hpa axis is reported to be closely related to acute stress-induced tau phosphorylation in the rodent hippocampus. 2015-01-22 2023-08-12 mouse
Li-Feng Zhang, Lv Shi, Hui Liu, Fan-Tao Meng, Ya-Jing Liu, Hui-Mei Wu, Xin Du, Jiang-Ning Zho. Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21418733. however, the relationship between the hyperactive hpa axis and tau phosphorylation in the hippocampus and hence the functional implications for chronic stress are not fully understood. 2015-01-22 2023-08-12 mouse
Li-Feng Zhang, Lv Shi, Hui Liu, Fan-Tao Meng, Ya-Jing Liu, Hui-Mei Wu, Xin Du, Jiang-Ning Zho. Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21418733. in this study, we aimed to examine tau phosphorylation and the effect on axonal transport of mitochondria in the hippocampus of a chronic stress model. 2015-01-22 2023-08-12 mouse
Li-Feng Zhang, Lv Shi, Hui Liu, Fan-Tao Meng, Ya-Jing Liu, Hui-Mei Wu, Xin Du, Jiang-Ning Zho. Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21418733. phosphorylated tau increased significantly, accompanied by increased synaptosomal mitochondrial levels in hippocampus of the chronic stress model. 2015-01-22 2023-08-12 mouse
Li-Feng Zhang, Lv Shi, Hui Liu, Fan-Tao Meng, Ya-Jing Liu, Hui-Mei Wu, Xin Du, Jiang-Ning Zho. Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21418733. crh receptor 1 antagonist (cp154,526) treatment, not glucocorticoid receptor antagonist (ru486) treatment, decreased tau phosphorylation and synaptosomal mitochondrial levels in the hippocampus of the mouse model. 2015-01-22 2023-08-12 mouse
Li-Feng Zhang, Lv Shi, Hui Liu, Fan-Tao Meng, Ya-Jing Liu, Hui-Mei Wu, Xin Du, Jiang-Ning Zho. Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21418733. consistent with an in-vivo model, when hyperphosphorylated tau was inhibited by lithium in cultured primary hippocampal neurons, mitochondrial transport monitored by live imaging was also decreased. 2015-01-22 2023-08-12 mouse
Li-Feng Zhang, Lv Shi, Hui Liu, Fan-Tao Meng, Ya-Jing Liu, Hui-Mei Wu, Xin Du, Jiang-Ning Zho. Increased hippocampal tau phosphorylation and axonal mitochondrial transport in a mouse model of chronic stress. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21418733. we show here for the first time that phosphorylated tau in the hippocampus of a chronic stress model, accompanied by increased mitochondrial transport, was mediated by crh receptor 1, not by glucocorticoid receptors, which suggests that centrally derived crh may be involved in the process of mitochondrial axon transport and hence play an important role in hippocampus of a chronic stress model. 2015-01-22 2023-08-12 mouse
Ming-Jang Chiu, Ya-Fang Chen, Ta-Fu Chen, Shieh-Yueh Yang, Fan-Pei Gloria Yang, Tien-Wen Tseng, Jen-Jie Chieh, Jia-Chun Rare Chen, Kai-Yuan Tzen, Mau-Sun Hua, Herng-Er Horn. Plasma tau as a window to the brain-negative associations with brain volume and memory function in mild cognitive impairment and early Alzheimer's disease. Human brain mapping. vol 35. issue 7. 2015-01-22. PMID:24129926. neurofibrillary tangles are associated with cognitive dysfunction, and hippocampal atrophy with increased csf tau markers. 2015-01-22 2023-08-12 Not clear