| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Hoshi, A Takashima, K Noguchi, M Murayama, M Sato, S Kondo, Y Saitoh, K Ishiguro, T Hoshino, K Imahor. Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 7. 1996-05-24. PMID:8610107. |
in rat hippocampal culture, betaa exposure activates tau protein kinase i/glycogen synthase kinase 3beta (tpki/gsk-3beta), which phosphorylates tau protein into alzheimer disease-like forms, resulting in neuronal death. |
1996-05-24 |
2023-08-12 |
rat |
| A Takashima, H Yamaguchi, K Noguchi, G Michel, K Ishiguro, K Sato, T Hoshino, M Hoshi, K Imahor. Amyloid beta peptide induces cytoplasmic accumulation of amyloid protein precursor via tau protein kinase I/glycogen synthase kinase-3 beta in rat hippocampal neurons. Neuroscience letters. vol 198. issue 2. 1996-04-04. PMID:8592647. |
amyloid beta peptide induces cytoplasmic accumulation of amyloid protein precursor via tau protein kinase i/glycogen synthase kinase-3 beta in rat hippocampal neurons. |
1996-04-04 |
2023-08-12 |
rat |
| P Vermersch, J P David, B Frigard, C Fallet-Bianco, A Wattez, H Petit, A Delacourt. Cortical mapping of Alzheimer pathology in brains of aged non-demented subjects. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 6. 1996-03-19. PMID:8584681. |
the abnormal tau triplet, a biochemical marker of neurofibrillary degeneration was quantified by western blot and densitometric analysis in several cortical areas including the entorhinal cortex (ec), hippocampus and brodmann areas (ba) 38, 20, 22, 35, 9, 44 and 39. |
1996-03-19 |
2023-08-12 |
human |
| P Vermersch, J P David, B Frigard, C Fallet-Bianco, A Wattez, H Petit, A Delacourt. Cortical mapping of Alzheimer pathology in brains of aged non-demented subjects. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 6. 1996-03-19. PMID:8584681. |
the abnormal tau triplet was detected in the ec and the hippocampus of most of the controls aged over 70 years. |
1996-03-19 |
2023-08-12 |
human |
| P Vermersch, J P David, B Frigard, C Fallet-Bianco, A Wattez, H Petit, A Delacourt. Cortical mapping of Alzheimer pathology in brains of aged non-demented subjects. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 6. 1996-03-19. PMID:8584681. |
the authors conclude that control cases with tau pathology in the temporal lobe and numerous sp in the neocortex were likely to be subclinical stages of ad whereas others with tau pathology exclusively detected in the ec and hippocampus and without or few sp in the neocortex were related to normal aging. |
1996-03-19 |
2023-08-12 |
human |
| R Brandt, J Léger, G Le. Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain. The Journal of cell biology. vol 131. issue 5. 1996-01-22. PMID:8522593. |
in hippocampal neurons, tau is differentially extracted by detergent and enriched in the growth cone and the distal axon when membrane is left intact. |
1996-01-22 |
2023-08-12 |
Not clear |
| C Schwab, J C Steele, H Akiyama, E G McGeer, P L McGee. Relationship of amyloid beta/A4 protein to the neurofibrillary tangles in Guamanian parkinsonism-dementia. Acta neuropathologica. vol 90. issue 3. 1996-01-19. PMID:8525803. |
we studied by immunohistochemistry the occurrence of intracellular and extracellular neurofibrillary tangles in lb in the entorhinal cortex, hippocampus and substantia nigra using antibodies to tau protein and ubiquitin. |
1996-01-19 |
2023-08-12 |
Not clear |
| J G Sheng, R E Mrak, W S Griffi. Microglial interleukin-1 alpha expression in brain regions in Alzheimer's disease: correlation with neuritic plaque distribution. Neuropathology and applied neurobiology. vol 21. issue 4. 1996-01-11. PMID:7494597. |
in alzheimer's disease, tau 2+ neuritic plaques occurred with increasing frequency in grey matter of frontal and occipital lobes, temporal lobe, and hippocampus. |
1996-01-11 |
2023-08-12 |
Not clear |
| R Durán, M C Arufe, B Arias, M Alfons. Effect of domoic acid on brain amino acid levels. Revista espanola de fisiologia. vol 51. issue 1. 1995-11-06. PMID:7569276. |
dose induces changes in the levels of amino acids of neurochemical interest (asp, glu, gly, tau, ala, gaba) in different rat brain regions (hypothalamus, hippocampus, amygdala, striatum, cortex and midbrain). |
1995-11-06 |
2023-08-12 |
rat |
| D Wang, D G Muno. Qualitative and quantitative differences in senile plaque dystrophic neurites of Alzheimer's disease and normal aged brain. Journal of neuropathology and experimental neurology. vol 54. issue 4. 1995-08-10. PMID:7602328. |
in cortical and hippocampal plaques in alzheimer's disease (ad) beta app colocalized with cga in a neuritic population largely distinct from the subset of neurites labeled by tau. |
1995-08-10 |
2023-08-12 |
human |
| D Wang, D G Muno. Qualitative and quantitative differences in senile plaque dystrophic neurites of Alzheimer's disease and normal aged brain. Journal of neuropathology and experimental neurology. vol 54. issue 4. 1995-08-10. PMID:7602328. |
neocortical and hippocampal plaques, the only common type in a group of elderly non-demented subjects (non-ad), incorporated cga/beta app, but not tau neurites. |
1995-08-10 |
2023-08-12 |
human |
| P M Moran, L S Higgins, B Cordell, P C Mose. Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human beta-amyloid precursor protein. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 12. 1995-07-12. PMID:7777509. |
transgenic mice expressing the 751-amino acid isoform of human beta-app (beta-app751) have been shown to develop early ad-like histopathology with diffuse deposits of beta-a4 and aberrant tau protein expression in the brain, particularly in the hippocampus, cortex, and amygdala. |
1995-07-12 |
2023-08-12 |
mouse |
| C R Breese, R Freedman, S S Leonar. Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers. Brain research. vol 674. issue 1. 1995-07-11. PMID:7773698. |
no significant changes were observed in schizophrenic hippocampal glur1 and glur5 receptor subtypes or in levels of the structural control proteins, ncam and tau. |
1995-07-11 |
2023-08-12 |
human |
| J Busciglio, A Lorenzo, J Yeh, B A Yankne. beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding. Neuron. vol 14. issue 4. 1995-05-23. PMID:7718249. |
to determine whether amyloid fibril formation affects the phosphorylation state of tau, primary cultures of fetal rat hippocampal and human cortical neurons were treated with beta-amyloid (beta a) in a soluble, amorphous-aggregated, or fibrillar form. |
1995-05-23 |
2023-08-12 |
human |
| C Vigo-Pelfrey, P Seubert, R Barbour, C Blomquist, M Lee, D Lee, F Coria, L Chang, B Miller, I Lieberbur. Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease. Neurology. vol 45. issue 4. 1995-05-23. PMID:7723971. |
postmortem analysis of two ad patients with high levels of csf tau revealed a high density of nfts in the hippocampus. |
1995-05-23 |
2023-08-12 |
human |
| N Arai, M I Papp, P L Lanto. New observation on ubiquitinated neurons in the cerebral cortex of multiple system atrophy (MSA). Neuroscience letters. vol 182. issue 2. 1995-05-17. PMID:7715809. |
to investigate neuronal damage in the cerebral cortex in patients with multiple system atrophy (msa), immunohistochemical stainings were carried out on the prefrontal cortex, the hippocampus, the precentral gyrus, the supplementary motor cortex and the occipital cortex in 6 cases of msa and 6 controls, using antibodies against ubiquitin, tau protein and neurofilaments (bf10, rt97, 147). |
1995-05-17 |
2023-08-12 |
Not clear |
| R M Torack, J W Mille. Denervation induced abnormal phosphorylation in hippocampal neurons. Brain research. vol 669. issue 1. 1995-05-12. PMID:7712157. |
this study demonstrates that combined dopaminergic and cholinergic denervation of the hippocampus results in the appearance of morphologically altered, tau reactive, apical dendrites of granule cells in the rat dentate gyrus. |
1995-05-12 |
2023-08-12 |
rat |
| T Horn, L Bauce, R Landgraf, Q J Pittma. Microdialysis with high NaCl causes central release of amino acids and dopamine. Journal of neurochemistry. vol 64. issue 4. 1995-04-18. PMID:7891091. |
in the dialysates of all perfusion areas, including the son, pvn, hippocampus, and striatum, concentrations of asp, glu, ser, gln, gly, taurine (tau), and gamma-aminobutyric acid (gaba) were significantly increased during perfusion with high-nacl medium. |
1995-04-18 |
2023-08-12 |
rat |
| T D Garver, K A Harris, R A Lehman, V M Lee, J Q Trojanowski, M L Billingsle. Tau phosphorylation in human, primate, and rat brain: evidence that a pool of tau is highly phosphorylated in vivo and is rapidly dephosphorylated in vitro. Journal of neurochemistry. vol 63. issue 6. 1994-12-23. PMID:7964748. |
tau was rapidly isolated from human temporal neocortex and hippocampus, rhesus monkey temporal neocortex, and rat temporal neocortex and hippocampus under conditions that minimized dephosphorylation. |
1994-12-23 |
2023-08-12 |
human |
| C Schwab, V Bondada, D L Sparks, L D Cahan, J W Gedde. Postmortem changes in the levels and localization of microtubule-associated proteins (tau, MAP2 and MAP1B) in the rat and human hippocampus. Hippocampus. vol 4. issue 2. 1994-12-20. PMID:7951696. |
postmortem changes in the levels and localization of microtubule-associated proteins (tau, map2 and map1b) in the rat and human hippocampus. |
1994-12-20 |
2023-08-12 |
human |