| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Simon Veedfald, Astrid Plamboeck, Carolyn F Deacon, Bolette Hartmann, Filip K Knop, Tina Vilsbøll, Jens J Hols. Cephalic phase secretion of insulin and other enteropancreatic hormones in humans. American journal of physiology. Gastrointestinal and liver physiology. vol 310. issue 1. 2016-05-02. PMID:26492921. |
despite adequate pp responses, a cephalic phase response was absent for insulin, glucagon, glp-1, gip, and ghrelin. |
2016-05-02 |
2023-08-13 |
human |
| Yanan Hou, Stephen A Ernst, Kaeli Heidenreich, John A William. Glucagon-like peptide-1 receptor is present in pancreatic acinar cells and regulates amylase secretion through cAMP. American journal of physiology. Gastrointestinal and liver physiology. vol 310. issue 1. 2016-05-02. PMID:26542397. |
glucagon-like peptide-1 (glp-1) is a glucoincretin hormone that can act through its receptor (glp-1r) on pancreatic β-cells and increase insulin secretion and production. |
2016-05-02 |
2023-08-13 |
mouse |
| Yanan Hou, Stephen A Ernst, Kaeli Heidenreich, John A William. Glucagon-like peptide-1 receptor is present in pancreatic acinar cells and regulates amylase secretion through cAMP. American journal of physiology. Gastrointestinal and liver physiology. vol 310. issue 1. 2016-05-02. PMID:26542397. |
glp-1 may also regulate the exocrine pancreas at multiple levels, including inhibition through the central nervous system, stimulation indirectly through insulin, and stimulation directly on acinar cells. |
2016-05-02 |
2023-08-13 |
mouse |
| Sony S Thazhath, Tongzhi Wu, Michelle J Bound, Helen L Checklin, Scott Standfield, Karen L Jones, Michael Horowitz, Christopher K Rayne. Administration of resveratrol for 5 wk has no effect on glucagon-like peptide 1 secretion, gastric emptying, or glycemic control in type 2 diabetes: a randomized controlled trial. The American journal of clinical nutrition. vol 103. issue 1. 2016-05-02. PMID:26607942. |
resveratrol has been reported to lower glycemia in rodent models of type 2 diabetes associated with the stimulation of glucagon-like peptide 1 (glp-1), which is known to slow gastric emptying, stimulate insulin secretion, and suppress glucagon secretion and energy intake. |
2016-05-02 |
2023-08-13 |
Not clear |
| Hye-Jung Kwon, Hyun-Sun Park, Sung-Hee Park, Jae-Hyung Park, Su-Kyung Shin, Seung Eun Song, Meeyul Hwang, Ho-Chan Cho, Dae-Kyu Son. Evidence for glucagon-like peptide-1 receptor signaling to activate ATP-sensitive potassium channels in pancreatic beta cells. Biochemical and biophysical research communications. vol 469. issue 2. 2016-05-02. PMID:26655814. |
glucagon-like peptide-1 (glp-1) is a gut peptide that promotes insulin release from pancreatic beta cells. |
2016-05-02 |
2023-08-13 |
rat |
| Astrid Plamboeck, Simon Veedfald, Carolyn F Deacon, Bolette Hartmann, Tina Vilsbøll, Filip K Knop, Jens J Hols. The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1. American journal of physiology. Regulatory, integrative and comparative physiology. vol 309. issue 5. 2016-04-26. PMID:26136531. |
glp-1 dose-dependently increased insulin secretion on both days. |
2016-04-26 |
2023-08-13 |
human |
| Masayuki Miuchi, Jun-ichiro Miyagawa, Mitsuyoshi Namb. [Significance of the regulation of hyperglucagonemia in type 2 diabetes mellitus]. Nihon rinsho. Japanese journal of clinical medicine. vol 73. issue 12. 2016-04-25. PMID:26666142. |
incretin, particularly glucagon like peptide-1 (glp-1) could control both α- and β-cell dysfunction, via the decrease of glucagon and the increase of insulin respectively. |
2016-04-25 |
2023-08-13 |
Not clear |
| Rune E Kuhre, Jens J Holst, Camilla Kapp. The regulation of function, growth and survival of GLP-1-producing L-cells. Clinical science (London, England : 1979). vol 130. issue 2. 2016-04-19. PMID:26637406. |
in addition to potentiation of meal-stimulated insulin secretion, glp-1 signalling exerts numerous pleiotropic effects on various tissues, regulating energy absorption and disposal, as well as cell proliferation and survival. |
2016-04-19 |
2023-08-13 |
Not clear |
| Rune E Kuhre, Jens J Holst, Camilla Kapp. The regulation of function, growth and survival of GLP-1-producing L-cells. Clinical science (London, England : 1979). vol 130. issue 2. 2016-04-19. PMID:26637406. |
in type 2 diabetes (t2d) reduced plasma levels of glp-1 have been observed, and plasma levels of glp-1, as well as reduced numbers of glp-1 producing cells, have been correlated to obesity and insulin resistance. |
2016-04-19 |
2023-08-13 |
Not clear |
| E Qvigstad, H L Gulseth, H Risstad, C W le Roux, T J Berg, T Mala, J A Kristinsso. A novel technique of Roux-en-Y gastric bypass reversal for postprandial hyperinsulinemic hypoglycaemia: A case report. International journal of surgery case reports. vol 21. 2016-04-18. PMID:26957187. |
we describe an evaluation of the effects of partial roux-en-y gastric bypass (rygb) reversal on postprandial hyperinsulinaemic hypoglycaemia, insulin and glp-1 levels. |
2016-04-18 |
2023-08-13 |
Not clear |
| Juris J Meier, Michael A Nauc. Incretin-based therapies: where will we be 50 years from now? Diabetologia. vol 58. issue 8. 2016-04-13. PMID:25994073. |
current developments include longer-acting glp-1 receptor agonists, fixed-ratio combinations of glp-1 analogues and basal insulin, as well as implantable osmotic minipumps for long-term delivery of glp-1 receptor agonists. |
2016-04-13 |
2023-08-13 |
Not clear |
| Lin Li, Ke Liu, Juan Zhao, Christian Holscher, Guang-Lai Li, Yue-Ze Li. Neuroprotective role of (Val(8))GLP-1-Glu-PAL in an in vitro model of Parkinson's disease. Neural regeneration research. vol 11. issue 2. 2016-04-13. PMID:27073388. |
here, we analyzed the neuroprotective effects of a novel protease-resistant glp-1 analogue, (val(8))glp-1-glu-pal, which has advantages over older analogues, such as improvement of hippocampal neurogenesis, glucose homeostasis, and insulin secretion. |
2016-04-13 |
2023-08-13 |
mouse |
| Xihua Zhong, Tianyi Zhang, Yuzhou Liu, Xin Wei, Xinji Zhang, Yingyi Qin, Zhichao Jin, Qi Chen, Xiuqiang Ma, Rui Wang, Jia H. Effects of three injectable antidiabetic agents on glycaemic control, weight change and drop-out in type 2 diabetes suboptimally controlled with metformin and/or a sulfonylurea: A network meta-analysis. Diabetes research and clinical practice. vol 109. issue 3. 2016-04-12. PMID:26233934. |
the objective of this review was to assess glucagon-like peptide-1 receptor agonists (glp-1 ras), basal insulin, and premixed insulin among participants with type 2 diabetes inadequately controlled with metformin and/or a sulfonylurea. |
2016-04-12 |
2023-08-13 |
human |
| Manuel Gil-Lozano, Paola M Hunter, Lucy-Ann Behan, Bojana Gladanac, Robert F Casper, Patricia L Brubake. Short-term sleep deprivation with nocturnal light exposure alters time-dependent glucagon-like peptide-1 and insulin secretion in male volunteers. American journal of physiology. Endocrinology and metabolism. vol 310. issue 1. 2016-04-12. PMID:26530153. |
the intestinal l cell is the principal source of glucagon-like peptide-1 (glp-1), a major determinant of insulin release. |
2016-04-12 |
2023-08-13 |
human |
| Manuel Gil-Lozano, Paola M Hunter, Lucy-Ann Behan, Bojana Gladanac, Robert F Casper, Patricia L Brubake. Short-term sleep deprivation with nocturnal light exposure alters time-dependent glucagon-like peptide-1 and insulin secretion in male volunteers. American journal of physiology. Endocrinology and metabolism. vol 310. issue 1. 2016-04-12. PMID:26530153. |
moreover, we separately tested the short-term effects of sleep deprivation and nocturnal light exposure on basal and postprandial glp-1, insulin, and glucose levels in the same volunteers. |
2016-04-12 |
2023-08-13 |
human |
| Manuel Gil-Lozano, Paola M Hunter, Lucy-Ann Behan, Bojana Gladanac, Robert F Casper, Patricia L Brubake. Short-term sleep deprivation with nocturnal light exposure alters time-dependent glucagon-like peptide-1 and insulin secretion in male volunteers. American journal of physiology. Endocrinology and metabolism. vol 310. issue 1. 2016-04-12. PMID:26530153. |
moreover, it also induced profound derangements in glp-1 and insulin responses such that postprandial glp-1 and insulin levels were markedly elevated and the normal variation in glp-1 responses was abrogated. |
2016-04-12 |
2023-08-13 |
human |
| M A de Laat, J M McGree, M N Sillenc. Equine hyperinsulinemia: investigation of the enteroinsular axis during insulin dysregulation. American journal of physiology. Endocrinology and metabolism. vol 310. issue 1. 2016-04-12. PMID:26530154. |
incretin hormones released from the proximal intestine, glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic peptide, augment insulin secretion in several species but require investigation in horses. |
2016-04-12 |
2023-08-13 |
Not clear |
| M A de Laat, J M McGree, M N Sillenc. Equine hyperinsulinemia: investigation of the enteroinsular axis during insulin dysregulation. American journal of physiology. Endocrinology and metabolism. vol 310. issue 1. 2016-04-12. PMID:26530154. |
insulin was also positively associated with the active amide of glp-1 following d-glucose and grain. |
2016-04-12 |
2023-08-13 |
Not clear |
| In-Seung Lee, Ki-Suk Kim, Kang-Hoon Kim, Jiyoung Park, Hyeon-Soo Jeong, Yumi Kim, Yun-Cheol Na, Won Seok Chung, Kwang-Seok Ahn, Seok-Geun Lee, Jae Young Um, Jun Hee Lee, Hyeung-Jin Jan. Antihyperglycemic and Antiobesity Effects of JAL2 on db/db Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2016-04-12. PMID:27069493. |
we performed oral glucose tolerance test (ogtt) and plasma glp-1 and insulin secretion by multiplex assays to investigate antidiabetic effects of ljt, rgl, and jal2 in db/db mice, the mice model of type 2 diabetes mellitus (t2dm). |
2016-04-12 |
2023-08-13 |
mouse |
| Mohamed-Sami Trabelsi, Mehdi Daoudi, Janne Prawitt, Sarah Ducastel, Véronique Touche, Sama I Sayin, Alessia Perino, Cheryl A Brighton, Yasmine Sebti, Jérôme Kluza, Olivier Briand, Hélène Dehondt, Emmanuelle Vallez, Emilie Dorchies, Grégory Baud, Valeria Spinelli, Nathalie Hennuyer, Sandrine Caron, Kadiombo Bantubungi, Robert Caiazzo, Frank Reimann, Philippe Marchetti, Philippe Lefebvre, Fredrik Bäckhed, Fiona M Gribble, Kristina Schoonjans, François Pattou, Anne Tailleux, Bart Staels, Sophie Lestave. Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells. Nature communications. vol 6. 2016-04-09. PMID:26134028. |
the bas-ba complex also induces glucagon-like peptide-1 (glp-1) production by l cells which potentiates β-cell glucose-induced insulin secretion. |
2016-04-09 |
2023-08-13 |
mouse |