| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Roger Reidelberger, Alvin Haver, Krista Anders, Bettye Apenteng, Craig Lani. Effects of solid-phase extraction of plasma in measuring gut metabolic hormones in fasted and fed blood of lean and diet-induced obese rats. Physiological reports. vol 4. issue 10. 2016-10-13. PMID:27207785. |
extraction of lean and obese plasma prior to assays produced consistent recoveries across assays for glp-1, pyy, amylin, ghrelin, and insulin, reflecting losses inherent to the extraction procedure. |
2016-10-13 |
2023-08-13 |
rat |
| Roger Reidelberger, Alvin Haver, Krista Anders, Bettye Apenteng, Craig Lani. Effects of solid-phase extraction of plasma in measuring gut metabolic hormones in fasted and fed blood of lean and diet-induced obese rats. Physiological reports. vol 4. issue 10. 2016-10-13. PMID:27207785. |
plasma extraction prior to assays generally revealed larger meal-induced changes in plasma glp-1, pyy, amylin, ghrelin, and insulin in lean and obese rats. |
2016-10-13 |
2023-08-13 |
rat |
| Jianguo Zhi, Suoping Zha. Effects of piragliatin, a glucokinase activator, on fasting and postprandial plasma glucose in patients with type 2 diabetes mellitus. Journal of clinical pharmacology. vol 56. issue 2. 2016-10-11. PMID:26183686. |
pd assessments included plasma glucose, insulin, c-peptide, glucagon, and glp-1. |
2016-10-11 |
2023-08-13 |
Not clear |
| Chiara Dalla Man, Francesco Micheletto, Matheni Sathananthan, Adrian Vella, Claudio Cobell. Model-Based Quantification of Glucagon-Like Peptide-1-Induced Potentiation of Insulin Secretion in Response to a Mixed Meal Challenge. Diabetes technology & therapeutics. vol 18. issue 1. 2016-10-11. PMID:26756104. |
glucagon-like peptide-1 (glp-1) is a powerful insulin secretagogue that is secreted in response to meal ingestion. |
2016-10-11 |
2023-08-13 |
Not clear |
| Chiara Dalla Man, Francesco Micheletto, Matheni Sathananthan, Adrian Vella, Claudio Cobell. Model-Based Quantification of Glucagon-Like Peptide-1-Induced Potentiation of Insulin Secretion in Response to a Mixed Meal Challenge. Diabetes technology & therapeutics. vol 18. issue 1. 2016-10-11. PMID:26756104. |
the ability to quantify the effect of glp-1 on insulin secretion could provide insights into the pathogenesis and treatment of diabetes. |
2016-10-11 |
2023-08-13 |
Not clear |
| Chiara Dalla Man, Francesco Micheletto, Matheni Sathananthan, Adrian Vella, Claudio Cobell. Model-Based Quantification of Glucagon-Like Peptide-1-Induced Potentiation of Insulin Secretion in Response to a Mixed Meal Challenge. Diabetes technology & therapeutics. vol 18. issue 1. 2016-10-11. PMID:26756104. |
we used a modification of a model of glp-1 action on insulin secretion using data from a hyperglycemic clamp with concomitant glp-1 infusion. |
2016-10-11 |
2023-08-13 |
Not clear |
| Corinna Lebherz, Florian Kahles, Katja Piotrowski, Michael Vogeser, Ann Christina Foldenauer, Kirsten Nassau, Erich Kilger, Nikolaus Marx, Klaus G Parhofer, Michael Lehrk. Interleukin-6 predicts inflammation-induced increase of Glucagon-like peptide-1 in humans in response to cardiac surgery with association to parameters of glucose metabolism. Cardiovascular diabetology. vol 15. 2016-10-11. PMID:26842302. |
glucagon-like peptide-1 (glp-1) is an incretin hormone, which gets secreted in response to nutritional stimuli from the gut mediating glucose-dependent insulin secretion. |
2016-10-11 |
2023-08-13 |
mouse |
| Martin M Grajowe. Adding Rapid-Acting Insulin or GLP-1 Receptor Agonist to Basal Insulin: Penny Wise and Pound Foolish? Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. vol 21. issue 1. 2016-10-07. PMID:25628120. |
adding rapid-acting insulin or glp-1 receptor agonist to basal insulin: penny wise and pound foolish? |
2016-10-07 |
2023-08-13 |
Not clear |
| L Østergaard, Christian S Frandsen, S Madsba. Treatment potential of the GLP-1 receptor agonists in type 2 diabetes mellitus: a review. Expert review of clinical pharmacology. vol 9. issue 2. 2016-10-07. PMID:26573176. |
glp-1 ras mimic the effects of native glp-1, which increases insulin secretion, inhibits glucagon secretion, increases satiety and slows gastric emptying. |
2016-10-07 |
2023-08-13 |
Not clear |
| L Østergaard, Christian S Frandsen, S Madsba. Treatment potential of the GLP-1 receptor agonists in type 2 diabetes mellitus: a review. Expert review of clinical pharmacology. vol 9. issue 2. 2016-10-07. PMID:26573176. |
the most common adverse events are nausea and other gastrointestinal discomfort, while hypoglycaemia is rarely reported when glp-1 ras not are combined with sulfonylurea or insulin. |
2016-10-07 |
2023-08-13 |
Not clear |
| L Østergaard, Christian S Frandsen, S Madsba. Treatment potential of the GLP-1 receptor agonists in type 2 diabetes mellitus: a review. Expert review of clinical pharmacology. vol 9. issue 2. 2016-10-07. PMID:26573176. |
treatment options in the near future will include co-formulations of basal insulin and a glp-1 ra. |
2016-10-07 |
2023-08-13 |
Not clear |
| Tiago P Guedes, Sofia Martins, Madalena Costa, Sofia S Pereira, Tiago Morais, Agostinho Santos, Mário Nora, Mariana P Monteir. Detailed characterization of incretin cell distribution along the human small intestine. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. vol 11. issue 6. 2016-10-05. PMID:26048514. |
incretin hormones, glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide 1 (glp-1), are physiologic stimulants of insulin release that have been implicated in diabetes remission after bariatric surgery. |
2016-10-05 |
2023-08-13 |
human |
| Bent J Nergård, Andreas Lindqvist, Hjörtur G Gislason, Leif Groop, Mikael Ekelund, Nils Wierup, Jan L Hedenbr. Mucosal glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide cell numbers in the super-obese human foregut after gastric bypass. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. vol 11. issue 6. 2016-10-05. PMID:26143297. |
it is established that roux-en-y gastric bypass (rygb) augments secretion of glucagon-like peptide-1 (glp-1), peptide tyrosine tyrosine (pyy), and insulin, but other aspects of gut hormone cell function in the alimentary limb are unknown. |
2016-10-05 |
2023-08-13 |
human |
| Natalie D Luscombe-Marsh, Amy T Hutchison, Stijn Soenen, Robert E Steinert, Peter M Clifton, Michael Horowitz, Christine Feinle-Bisse. Plasma Free Amino Acid Responses to Intraduodenal Whey Protein, and Relationships with Insulin, Glucagon-Like Peptide-1 and Energy Intake in Lean Healthy Men. Nutrients. vol 8. issue 1. 2016-10-05. PMID:26742062. |
this study determined the effects of increasing loads of intraduodenal (id) dairy protein on plasma amino acid (aa) concentrations, and their relationships with serum insulin, plasma glucagon-like peptide-1 (glp-1) and energy intake. |
2016-10-05 |
2023-08-13 |
Not clear |
| Natalie D Luscombe-Marsh, Amy T Hutchison, Stijn Soenen, Robert E Steinert, Peter M Clifton, Michael Horowitz, Christine Feinle-Bisse. Plasma Free Amino Acid Responses to Intraduodenal Whey Protein, and Relationships with Insulin, Glucagon-Like Peptide-1 and Energy Intake in Lean Healthy Men. Nutrients. vol 8. issue 1. 2016-10-05. PMID:26742062. |
sixteen healthy men had concentrations of aas, glp-1 and insulin measured in response to 60-min id infusions of hydrolysed whey protein administered, in double-blinded and randomised order, at 2.1 (p2.1), 6.3 (p6.3) or 12.5 (p12.5) kj/min (encompassing the range of nutrient emptying from the stomach), or saline control (c). |
2016-10-05 |
2023-08-13 |
Not clear |
| Natalie D Luscombe-Marsh, Amy T Hutchison, Stijn Soenen, Robert E Steinert, Peter M Clifton, Michael Horowitz, Christine Feinle-Bisse. Plasma Free Amino Acid Responses to Intraduodenal Whey Protein, and Relationships with Insulin, Glucagon-Like Peptide-1 and Energy Intake in Lean Healthy Men. Nutrients. vol 8. issue 1. 2016-10-05. PMID:26742062. |
the auc0-60 min for each aa was correlated directly with the auc0-60 min of insulin (r² range 0.3-0.6), glp-1 (0.2-0.6) and energy intake (0.09-0.3) (p < 0.05, for all), with the strongest correlations being for branched-chain aas, lysine, methionine and tyrosine. |
2016-10-05 |
2023-08-13 |
Not clear |
| Natalie D Luscombe-Marsh, Amy T Hutchison, Stijn Soenen, Robert E Steinert, Peter M Clifton, Michael Horowitz, Christine Feinle-Bisse. Plasma Free Amino Acid Responses to Intraduodenal Whey Protein, and Relationships with Insulin, Glucagon-Like Peptide-1 and Energy Intake in Lean Healthy Men. Nutrients. vol 8. issue 1. 2016-10-05. PMID:26742062. |
these findings indicate that id whey protein infused at loads encompassing the normal range of gastric emptying increases plasma concentrations of 19/20 aas in a load-dependent manner, and provide novel information on the close relationships between the essential aas, leucine, valine, isoleucine, lysine, methionine, and the conditionally-essential aa, tyrosine, with energy intake, insulin and glp-1. |
2016-10-05 |
2023-08-13 |
Not clear |
| C J McMillan, R C Zapata, P K Chelikani, E C R Snead, K Cosfor. Circulating concentrations of glucagon-like peptide 1, glucose-dependent insulinotropic peptide, peptide YY, and insulin in client-owned lean, overweight, and diabetic cats. Domestic animal endocrinology. vol 54. 2016-09-30. PMID:26609567. |
results showed that plasma concentrations of glp-1, gip, pyy, and insulin increased in general after a meal in all study groups. |
2016-09-30 |
2023-08-13 |
Not clear |
| b' K Zem\\xc3\\xa1nkov\\xc3\\xa1, J Mr\\xc3\\xa1zkov\\xc3\\xa1, J Pi\\xc5\\xa5ha, J Kov\\xc3\\xa1\\xc5\\x9. The effect of glucose when added to a fat load on the response of glucagon-like peptide-1 (GLP-1) and apolipoprotein B-48 in the postprandial phase. Physiological research. vol 64. issue Suppl 3. 2016-09-27. PMID:26680669.' |
the addition of glucose induced the physiological response of insulin and the lower response of glp-1 to the test meal during the early postprandial phase, but had no effect on changes of trl-cholesterol and trl-tg within 8 h after the meal. |
2016-09-27 |
2023-08-13 |
human |
| Baptist Gallwit. Glucagon-like peptide-1 and gastric inhibitory polypeptide: new advances. Current opinion in endocrinology, diabetes, and obesity. vol 23. issue 1. 2016-09-27. PMID:26702848. |
glucagon-like peptide-1 (glp-1) and gastric inhibitory polypeptide (gip) are gastrointestinal peptides that play an important role as incretin hormones in the regulation of plasma glucose and insulin secretion. |
2016-09-27 |
2023-08-13 |
Not clear |