| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mehmet Gokhan Culha, Ahmet Cagkan Inkaya, Emre Yildirim, Serhat Unal, Ege Can Serefogl. Glucagon like peptide-1 receptor agonists may ameliorate the metabolic adverse effect associated with antiretroviral therapy. Medical hypotheses. vol 94. 2017-06-16. PMID:27515222. |
glucagon-like peptide-1 (glp-1) is a neuropeptide secreted from intestinal l cells and recently developed glp-1 receptor agonists (glp-1ras) stimulate insulin secretion, improve weight control and reduce cardiovascular outcomes. |
2017-06-16 |
2023-08-13 |
Not clear |
| Yuta Maekawa, Akihiko Sugiyama, Takashi Takeuch. Lactoferrin potentially facilitates glucose regulation and enhances the incretin effect. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 95. issue 1. 2017-06-14. PMID:28177763. |
these results suggest that lf could suppress hyperglycemia, accompanied by elevated plasma levels of insulin via transiently accelerating glp-1 secretion, and that lf even enhances glucose absorption from the small intestine. |
2017-06-14 |
2023-08-13 |
rat |
| Zhu Zeng, Rui Yu, Fanglei Zuo, Bo Zhang, Deju Peng, Huiqin Ma, Shangwu Che. Heterologous Expression and Delivery of Biologically Active Exendin-4 by Lactobacillus paracasei L14. PloS one. vol 11. issue 10. 2017-06-13. PMID:27764251. |
the secreted exendin-4 significantly enhanced insulin secretion of ins-1 β-cells, along with an increment in their proliferation and inhibition of their apoptosis, corresponding to the effect of glp-1 on these cells. |
2017-06-13 |
2023-08-13 |
Not clear |
| Lauge Østergaard, Christian Seerup Frandsen, Thomas Fremming Dejgaard, Sten Madsba. Fixed-ratio combination therapy with GLP-1 receptor agonist liraglutide and insulin degludec in people with type 2 diabetes. Expert review of clinical pharmacology. vol 10. issue 6. 2017-06-08. PMID:28349716. |
fixed-ratio combination therapy with glp-1 receptor agonist liraglutide and insulin degludec in people with type 2 diabetes. |
2017-06-08 |
2023-08-13 |
Not clear |
| Jenny Tong, Harold W Davis, Amalia Gastaldelli, David D'Alessi. Ghrelin Impairs Prandial Glucose Tolerance and Insulin Secretion in Healthy Humans Despite Increasing GLP-1. The Journal of clinical endocrinology and metabolism. vol 101. issue 6. 2017-06-07. PMID:27055279. |
ghrelin impairs prandial glucose tolerance and insulin secretion in healthy humans despite increasing glp-1. |
2017-06-07 |
2023-08-13 |
human |
| Jill S Carmody, Rodrigo Muñoz, Huali Yin, Lee M Kapla. Peripheral, but not central, GLP-1 receptor signaling is required for improvement in glucose tolerance after Roux-en-Y gastric bypass in mice. American journal of physiology. Endocrinology and metabolism. vol 310. issue 10. 2017-06-06. PMID:27026085. |
after rygb, levels of glucagon-like peptide-1 (glp-1), a hormone that enhances insulin secretion and promotes satiation, are substantially elevated. |
2017-06-06 |
2023-08-13 |
mouse |
| Nikkie van der Wielen, Jean Paul Ten Klooster, Susanne Muckenschnabl, Raymond Pieters, Henk Fj Hendriks, Renger F Witkamp, Jocelijn Meijerin. The Noncaloric Sweetener Rebaudioside A Stimulates Glucagon-Like Peptide 1 Release and Increases Enteroendocrine Cell Numbers in 2-Dimensional Mouse Organoids Derived from Different Locations of the Intestine. The Journal of nutrition. vol 146. issue 12. 2017-06-06. PMID:27798332. |
glucagon-like peptide 1 (glp-1) contributes to satiety and plays a pivotal role in insulin secretion and glucose homeostasis. |
2017-06-06 |
2023-08-13 |
mouse |
| Zhiying Zhang, Huifang Liu, Qiang L. Glucagon-like peptide-1 effects lipotoxic oxidative stress by regulating the expression of microRNAs. Biochemical and biophysical research communications. vol 482. issue 4. 2017-06-06. PMID:27956176. |
aim to confirm whether the treatment of glp-1 can modulated body weight, lipid metabolism, insulin content, pancreas oxidative stress, improved t-aoc, mda levels related to ffa-induced oxidative stress in c57bl/6 mice and ins-1 cells. |
2017-06-06 |
2023-08-13 |
mouse |
| Annalisa Natalicchio, Giuseppina Biondi, Nicola Marrano, Rossella Labarbuta, Federica Tortosa, Rosaria Spagnuolo, Rossella D'Oria, Emanuele Carchia, Anna Leonardini, Angelo Cignarelli, Sebastio Perrini, Luigi Laviola, Francesco Giorgin. Long-Term Exposure of Pancreatic β-Cells to Palmitate Results in SREBP-1C-Dependent Decreases in GLP-1 Receptor Signaling via CREB and AKT and Insulin Secretory Response. Endocrinology. vol 157. issue 6. 2017-06-05. PMID:27035653. |
long-term exposure of pancreatic β-cells to palmitate results in srebp-1c-dependent decreases in glp-1 receptor signaling via creb and akt and insulin secretory response. |
2017-06-05 |
2023-08-13 |
mouse |
| Annalisa Natalicchio, Giuseppina Biondi, Nicola Marrano, Rossella Labarbuta, Federica Tortosa, Rosaria Spagnuolo, Rossella D'Oria, Emanuele Carchia, Anna Leonardini, Angelo Cignarelli, Sebastio Perrini, Luigi Laviola, Francesco Giorgin. Long-Term Exposure of Pancreatic β-Cells to Palmitate Results in SREBP-1C-Dependent Decreases in GLP-1 Receptor Signaling via CREB and AKT and Insulin Secretory Response. Endocrinology. vol 157. issue 6. 2017-06-05. PMID:27035653. |
finally, treatment of ins-1e cells with metformin for 24 h resulted in inhibition of srebp-1c expression, increased pdx-1 and glp-1 receptor levels, consequently, enhancement of exendin-4-induced insulin release. |
2017-06-05 |
2023-08-13 |
mouse |
| Bettina K Wölnerhanssen, Lucian Cajacob, Nino Keller, Alison Doody, Jens F Rehfeld, Juergen Drewe, Ralph Peterli, Christoph Beglinger, Anne Christin Meyer-Gerspac. Gut hormone secretion, gastric emptying, and glycemic responses to erythritol and xylitol in lean and obese subjects. American journal of physiology. Endocrinology and metabolism. vol 310. issue 11. 2017-06-05. PMID:27117004. |
we examined plasma glucose, insulin, active glp-1, cck, and ge with a [(13)c]sodium acetate breath test and assessed subjective feelings of satiation. |
2017-06-05 |
2023-08-13 |
human |
| Bettina K Wölnerhanssen, Lucian Cajacob, Nino Keller, Alison Doody, Jens F Rehfeld, Juergen Drewe, Ralph Peterli, Christoph Beglinger, Anne Christin Meyer-Gerspac. Gut hormone secretion, gastric emptying, and glycemic responses to erythritol and xylitol in lean and obese subjects. American journal of physiology. Endocrinology and metabolism. vol 310. issue 11. 2017-06-05. PMID:27117004. |
xylitol and erythritol led to a marked increase in cck and glp-1, whereas insulin and plasma glucose were not (erythritol) or only slightly (xylitol) affected. |
2017-06-05 |
2023-08-13 |
human |
| Nicola Basso, Emanuele Soricelli, Lidia Castagneto-Gissey, Giovanni Casella, Davide Albanese, Francesca Fava, Claudio Donati, Kieran Tuohy, Giulia Angelini, Federica La Neve, Anna Severino, Virginia Kamvissi-Lorenz, Andrea L Birkenfeld, Stefan Bornstein, Melania Manco, Geltrude Mingron. Insulin Resistance, Microbiota, and Fat Distribution Changes by a New Model of Vertical Sleeve Gastrectomy in Obese Rats. Diabetes. vol 65. issue 10. 2017-05-19. PMID:27431457. |
we found a reduction of circulating ghrelin levels, increased glp-1 plasma concentration, and remodeling of gut microbiome diversity characterized by a lower relative abundance of ruminococcus and a higher relative abundance of lactobacillus and collinsella these data suggest that at least in rat, the glandular stomach plays a central role in the improvement of insulin resistance, even if obesity persists. |
2017-05-19 |
2023-08-13 |
rat |
| Jeanne H Bottin, Jonathan R Swann, Eleanor Cropp, Edward S Chambers, Heather E Ford, Mohammed A Ghatei, Gary S Fros. Mycoprotein reduces energy intake and postprandial insulin release without altering glucagon-like peptide-1 and peptide tyrosine-tyrosine concentrations in healthy overweight and obese adults: a randomised-controlled trial. The British journal of nutrition. vol 116. issue 2. 2017-05-17. PMID:27198187. |
visual analogue scales and blood samples were collected to measure appetite, glucose, insulin, peptide tyrosine-tyrosine (pyy) and glucagon-like peptide-1 (glp-1). |
2017-05-17 |
2023-08-13 |
human |
| Isabella Lee, Lin Shi, Dominic-Luc Webb, Per M Hellström, Ulf Risérus, Rikard Landber. Effects of whole-grain rye porridge with added inulin and wheat gluten on appetite, gut fermentation and postprandial glucose metabolism: a randomised, cross-over, breakfast study. The British journal of nutrition. vol 116. issue 12. 2017-05-12. PMID:28069076. |
appetite, breath hydrogen and methane, glucose, insulin and glucagon-like peptide-1 (glp-1) responses were measured over 8 h. twenty-one healthy men and women, aged 23-60 years, with bmi of 21-33 kg/m2 participated in this study. |
2017-05-12 |
2023-08-13 |
Not clear |
| Isabella Lee, Lin Shi, Dominic-Luc Webb, Per M Hellström, Ulf Risérus, Rikard Landber. Effects of whole-grain rye porridge with added inulin and wheat gluten on appetite, gut fermentation and postprandial glucose metabolism: a randomised, cross-over, breakfast study. The British journal of nutrition. vol 116. issue 12. 2017-05-12. PMID:28069076. |
no differences were observed in ad libitum food intake, insulin or glp-1. |
2017-05-12 |
2023-08-13 |
Not clear |
| Alastair D Green, Srividya Vasu, Peter R Flat. Functionality and antidiabetic utility of β- and L-cell containing pseudoislets. Experimental cell research. vol 344. issue 2. 2017-05-08. PMID:27068377. |
here, the therapeutic potential of pseudoislets generated from the insulin and glp-1 releasing cell-lines min6 and glutag was investigated. |
2017-05-08 |
2023-08-13 |
mouse |
| Alastair D Green, Srividya Vasu, Peter R Flat. Functionality and antidiabetic utility of β- and L-cell containing pseudoislets. Experimental cell research. vol 344. issue 2. 2017-05-08. PMID:27068377. |
implantation of pseudoislets into streptozotocin-diabetic scid mice precipitated cell masses containing immunoreactive insulin and glp-1. |
2017-05-08 |
2023-08-13 |
mouse |
| Alastair D Green, Srividya Vasu, Peter R Flat. Functionality and antidiabetic utility of β- and L-cell containing pseudoislets. Experimental cell research. vol 344. issue 2. 2017-05-08. PMID:27068377. |
in contract, combined pseudoislet recipients achieved tempered restoration of normoglycaemia and exhibited increased plasma glp-1, decreased plasma and pancreatic glucagon, increased pancreatic insulin and enhancements in islet β:α cells and the ratio of ki67: tunel positive β-cells. |
2017-05-08 |
2023-08-13 |
mouse |
| Alastair D Green, Srividya Vasu, Peter R Flat. Functionality and antidiabetic utility of β- and L-cell containing pseudoislets. Experimental cell research. vol 344. issue 2. 2017-05-08. PMID:27068377. |
our observations highlight the potential of combining insulin and glp-1 cell therapy using heterotypic pseudoislets. |
2017-05-08 |
2023-08-13 |
mouse |