| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Éva A Csajbók, Ágnes K Kocsis, Nóra Faragó, Szabina Furdan, Balázs Kovács, Sándor Lovas, Gábor Molnár, István Likó, Ágnes Zvara, László G Puskás, Attila Patócs, Gábor Tamá. Expression of GLP-1 receptors in insulin-containing interneurons of rat cerebral cortex. Diabetologia. vol 62. issue 4. 2020-02-18. PMID:30637442. |
glucagon-like peptide 1 (glp-1) receptors are expressed by pancreatic beta cells and glp-1 receptor signalling promotes insulin secretion. |
2020-02-18 |
2023-08-13 |
rat |
| Éva A Csajbók, Ágnes K Kocsis, Nóra Faragó, Szabina Furdan, Balázs Kovács, Sándor Lovas, Gábor Molnár, István Likó, Ágnes Zvara, László G Puskás, Attila Patócs, Gábor Tamá. Expression of GLP-1 receptors in insulin-containing interneurons of rat cerebral cortex. Diabetologia. vol 62. issue 4. 2020-02-18. PMID:30637442. |
our previous results showed that insulin is released by neurogliaform neurons in the cerebral cortex, but the expression of glp-1 receptors on insulin-producing neocortical neurons has not been tested. |
2020-02-18 |
2023-08-13 |
rat |
| Christina M Gant, Ijmke Mensink, S Heleen Binnenmars, Job A M van der Palen, Stephan J L Bakker, Gerjan Navis, Gozewijn D Laverma. Body weight course in the DIAbetes and LifEstyle Cohort Twente (DIALECT-1)-A 20-year observational study. PloS one. vol 14. issue 6. 2020-02-13. PMID:31216324. |
we assessed weight course in a real-life diabetes secondary care setting and analyzed its association with patient characteristics, lifestyle habits and initiation of insulin, glucagon like peptide-1 receptor agonists (glp-1 ra) and sodium-glucose co-transporter-2 inhibitors (sglt-2i). |
2020-02-13 |
2023-08-13 |
Not clear |
| Domenico Tricò, Silvia Frascerra, Simona Baldi, Alessandro Mengozzi, Lorenzo Nesti, Andrea Mari, Andrea Natal. The insulinotropic effect of a high-protein nutrient preload is mediated by the increase of plasma amino acids in type 2 diabetes. European journal of nutrition. vol 58. issue 6. 2020-02-12. PMID:30008106. |
eating protein before carbohydrate reduces postprandial glucose excursions by enhancing insulin and glucagon-like peptide-1 (glp-1) secretion in type 2 diabetes (t2d). |
2020-02-12 |
2023-08-13 |
Not clear |
| Xiudao Song, Liang Zhou, Heng Xu, Fei Wang, Guoqiang Liang, Lurong Zhang, Fei Huang, Guorong Jian. 3-Deoxyglucosone interferes with insulin signaling and attenuates insulin action on glucose-induced GLP-1 secretion in the enteroendocrine L cell line STC-1. Molecular biology reports. vol 46. issue 5. 2020-02-12. PMID:31228040. |
3-deoxyglucosone interferes with insulin signaling and attenuates insulin action on glucose-induced glp-1 secretion in the enteroendocrine l cell line stc-1. |
2020-02-12 |
2023-08-13 |
Not clear |
| Xiudao Song, Liang Zhou, Heng Xu, Fei Wang, Guoqiang Liang, Lurong Zhang, Fei Huang, Guorong Jian. 3-Deoxyglucosone interferes with insulin signaling and attenuates insulin action on glucose-induced GLP-1 secretion in the enteroendocrine L cell line STC-1. Molecular biology reports. vol 46. issue 5. 2020-02-12. PMID:31228040. |
maintenance of glucose homeostasis is reciprocally regulated by insulin and glucagon-like peptide-1 (glp-1). |
2020-02-12 |
2023-08-13 |
Not clear |
| Xiudao Song, Liang Zhou, Heng Xu, Fei Wang, Guoqiang Liang, Lurong Zhang, Fei Huang, Guorong Jian. 3-Deoxyglucosone interferes with insulin signaling and attenuates insulin action on glucose-induced GLP-1 secretion in the enteroendocrine L cell line STC-1. Molecular biology reports. vol 46. issue 5. 2020-02-12. PMID:31228040. |
here we investigated the effects of 3dg on insulin signaling and insulin-induced glp-1 secretion under high-glucose conditions in the enteroendocrine l cell line stc-1. |
2020-02-12 |
2023-08-13 |
Not clear |
| Bowen Xing, Jian Ma, Zongzhe Jiang, Zijie Feng, Sunbin Ling, Katy Szigety, Wen Su, Longmei Zhang, Ruirui Jia, Yanmei Sun, Lin Zhang, Xiangchen Kong, Xiaosong Ma, Xianxin Hu. GLP-1 signaling suppresses menin's transcriptional block by phosphorylation in β cells. The Journal of cell biology. vol 218. issue 3. 2020-02-10. PMID:30792230. |
here, we show that glp-1 signaling-activated protein kinase a (pka) directly phosphorylates menin at the serine 487 residue, relieving menin-mediated suppression of insulin expression and cell proliferation. |
2020-02-10 |
2023-08-13 |
Not clear |
| Stephen M Day, Wenzhong Yang, Xin Wang, Jennifer E Stern, Xueyan Zhou, Shannon L Macauley, Tao M. Glucagon-Like Peptide-1 Cleavage Product Improves Cognitive Function in a Mouse Model of Down Syndrome. eNeuro. vol 6. issue 2. 2020-02-10. PMID:31040160. |
glucagon-like peptide-1 (glp-1) is an incretin hormone that maintains glucose homeostasis by stimulating insulin secretion. |
2020-02-10 |
2023-08-13 |
mouse |
| Teresa Salvatore, Riccardo Nevola, Pia Clara Pafundi, Lucio Monaco, Carmen Ricozzi, Simona Imbriani, Luca Rinaldi, Ferdinando Carlo Sass. Incretin Hormones: The Link between Glycemic Index and Cardiometabolic Diseases. Nutrients. vol 11. issue 8. 2020-02-10. PMID:31412576. |
incretin hormones, glucagon-like peptide1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip), are important regulators of postprandial homeostasis by amplifying insulin secretory responses. |
2020-02-10 |
2023-08-13 |
Not clear |
| Jens Juul Hols. The incretin system in healthy humans: The role of GIP and GLP-1. Metabolism: clinical and experimental. vol 96. 2020-02-07. PMID:31029770. |
the main mechanism behind it is stimulation of insulin secretion by a proportional secretion of the insulinotropic hormones gip and glp-1. |
2020-02-07 |
2023-08-13 |
Not clear |
| Jens Juul Hols. The incretin system in healthy humans: The role of GIP and GLP-1. Metabolism: clinical and experimental. vol 96. 2020-02-07. PMID:31029770. |
gip seems to be quantitatively the most important, particularly regarding insulin secretion, whereas the action of glp-1 is mainly displayed via inhibition of glucagon secretion. |
2020-02-07 |
2023-08-13 |
Not clear |
| Caroline C Øhrstrøm, Filip K Kno. A role for exogenous GLP-1 in the management of postprandial hypoglycaemia after Roux-en-Y gastric bypass? European journal of endocrinology. vol 181. issue 3. 2020-02-06. PMID:31370002. |
the mechanisms underlying pbh most likely relate to accelerated delivery of nutrients to the small intestine resulting in unretarded nutrient absorption, large elevations in postprandial plasma glucose concentrations (constituting a potent insulin secretory stimulus), and grossly elevated postprandial plasma levels of the insulinotropic gut-derived hormone glucagon-like peptide 1 (glp-1) potentiating glucose-stimulated insulin secretion. |
2020-02-06 |
2023-08-13 |
Not clear |
| Joseph Yi Zhou, Anil Poudel, Ryan Welchko, Naveen Mekala, Prashanth Chandramani-Shivalingappa, Mariana Georgeta Rosca, Lixin L. Liraglutide improves insulin sensitivity in high fat diet induced diabetic mice through multiple pathways. European journal of pharmacology. vol 861. 2020-02-06. PMID:31412267. |
glucagon like peptide-1 (glp-1) promotes postprandial insulin secretion. |
2020-02-06 |
2023-08-13 |
mouse |
| Joseph Yi Zhou, Anil Poudel, Ryan Welchko, Naveen Mekala, Prashanth Chandramani-Shivalingappa, Mariana Georgeta Rosca, Lixin L. Liraglutide improves insulin sensitivity in high fat diet induced diabetic mice through multiple pathways. European journal of pharmacology. vol 861. 2020-02-06. PMID:31412267. |
liraglutide, a full agonist of the glp-1 receptor, reduces body weight, improve insulin sensitivity, and alleviate non alcoholic fatty liver disease (nafld). |
2020-02-06 |
2023-08-13 |
mouse |
| Mei-Yueh Lee, Wei-Chun Chen, Wei-Hao Hsu, Szu-Chia Chen, Jin-Ching Le. Liraglutide Inhibits Hepatitis C Virus Replication Through an AMP Activated Protein Kinase Dependent Mechanism. International journal of molecular sciences. vol 20. issue 18. 2020-02-06. PMID:31540136. |
insulin resistance and diabetes are both associated with chronic hepatitis c virus (hcv) infection, and the glucagon-like peptide-1(glp-1) receptor agonist, liraglutide, is a common therapy for diabetes. |
2020-02-06 |
2023-08-13 |
Not clear |
| Raishi Ichikawa, Koji Takano, Kazumi Fujimoto, Tetsuya Motomiya, Masaki Kobayashi, Tadahiro Kitamura, Masayoshi Shichir. Basal glucagon hypersecretion and response to oral glucose load in prediabetes and mild type 2 diabetes. Endocrine journal. vol 66. issue 8. 2020-02-03. PMID:31142688. |
plasma glucose, insulin, glucagon and active glp-1 were also measured. |
2020-02-03 |
2023-08-13 |
human |
| Tianrui Yang, B Tate Cutshall, Alexandra Tatara, Melanie Ruegge. Combined Insulin and GLP-1 Receptor Agonists: Simplifying Treatment or Adding Obstacles? Journal of pharmacy practice. vol 32. issue 4. 2020-01-29. PMID:30270723. |
combined insulin and glp-1 receptor agonists: simplifying treatment or adding obstacles? |
2020-01-29 |
2023-08-13 |
Not clear |
| Lisse Angarita Dávila, Valmore Bermúdez, Daniel Aparicio, Virginia Céspedes, Ma Cristina Escobar, Samuel Durán-Agüero, Silvana Cisternas, Jorge de Assis Costa, Diana Rojas-Gómez, Nadia Reyna, Jose López-Mirand. Effect of Oral Nutritional Supplements with Sucromalt and Isomaltulose versus Standard Formula on Glycaemic Index, Entero-Insular Axis Peptides and Subjective Appetite in Patients with Type 2 Diabetes: A Randomised Cross-Over Study. Nutrients. vol 11. issue 7. 2020-01-29. PMID:31261732. |
this randomised, double-blind, cross-over study compared postprandial effects of ons-d with isomaltulose and sucromalt versus standard formula (et) on glycaemic index (gi), insulin, glucose-dependent insulinotropic polypeptide (gip), glucagon-like peptide 1 (glp-1) and sa in 16 individuals with dm2. |
2020-01-29 |
2023-08-13 |
human |
| Leigh Perreault, Helena Rodbard, Virginia Valentine, Eric Johnso. Optimizing Fixed-Ratio Combination Therapy in Type 2 Diabetes. Advances in therapy. vol 36. issue 2. 2020-01-22. PMID:30610613. |
glucagon-like peptide-1 receptor agonists (glp-1 ras) provide an alternative to prandial insulin, with the benefits of fewer daily injections, and a lower risk of hypoglycemia and weight gain. |
2020-01-22 |
2023-08-13 |
Not clear |