| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pengzhou Li, Liyong Zhu, Xiangwu Yang, Weizheng Li, Xulong Sun, Bo Yi, Shaihong Zh. Farnesoid X receptor interacts with cAMP response element binding protein to modulate glucagon-like peptide-1 (7-36) amide secretion by intestinal L cell. Journal of cellular physiology. vol 234. issue 8. 2020-05-12. PMID:30536761. |
glucagon-like peptide-1 (7-36) amide (glp-1) is a gut hormone released from the l cells which stimulate insulin secretion and promotes insulin gene expression and β-cell growth and differentiation. |
2020-05-12 |
2023-08-13 |
mouse |
| Rune Ehrenreich Kuhre, Charlotte Bayer Christiansen, Seyed Mojtaba Ghiasi, Maria Buur Nordskov Gabe, Patricia Almine Skat-Rørdam, Ida Marie Modvig, Thomas Mandrup-Poulsen, Reidar Albrechtsen, Mette Marie Rosenkilde, Bolette Hartmann, Nicolai Jacob Wewer Albrechtsen, Jens Juul Hols. Neuromedin U Does Not Act as a Decretin in Rats. Cell metabolism. vol 29. issue 3. 2020-05-11. PMID:30449683. |
unlike the incretin hormone, glucagon-like peptide 1 (glp-1), intravenous nmu administration had no effects on blood glucose and plasma insulin and glucagon in vivo. |
2020-05-11 |
2023-08-13 |
human |
| Joseph Zhou, Anil Poudel, Prashanth Chandramani-Shivalingappa, Biao Xu, Ryan Welchko, Lixin L. Liraglutide induces beige fat development and promotes mitochondrial function in diet induced obesity mice partially through AMPK-SIRT-1-PGC1-α cell signaling pathway. Endocrine. vol 64. issue 2. 2020-05-11. PMID:30535743. |
glucagon like peptide-1 (glp-1) is produced to induce postprandial insulin secretion. |
2020-05-11 |
2023-08-13 |
mouse |
| Daniel E Newmire, Eric Rivas, Sarah E Deemer, Darryn S Willoughby, Victor Ben-Ezr. The Impact of a Large Bolus Dose of l-leucine and l-isoleucine on Enteroendocrine and Pancreatic Hormones, and Glycemia in Healthy, Inactive Adults. Nutrients. vol 11. issue 11. 2020-05-08. PMID:31689951. |
the ingestion of whey protein and amino acids with carbohydrate (cho) enhances the release of glucagon-like peptide-1 (glp-1) and glucose-dependent-insulinotropic peptide (gip) that promote insulin secretion. |
2020-05-08 |
2023-08-13 |
Not clear |
| Benedikt A Aulinger, Marta Perabo, Randy J Seeley, Klaus G Parhofer, David A D'Alessi. Rapid hepatic metabolism blunts the endocrine action of portally infused GLP-1 in male rats. American journal of physiology. Endocrinology and metabolism. vol 318. issue 2. 2020-05-04. PMID:31743041. |
an alternative mechanism for glp-1 to regulate insulin secretion through neuroendocrine signaling originating from sensors in the portal vein has been proposed. |
2020-05-04 |
2023-08-13 |
rat |
| Benedikt A Aulinger, Marta Perabo, Randy J Seeley, Klaus G Parhofer, David A D'Alessi. Rapid hepatic metabolism blunts the endocrine action of portally infused GLP-1 in male rats. American journal of physiology. Endocrinology and metabolism. vol 318. issue 2. 2020-05-04. PMID:31743041. |
we hypothesized that portal infusion of glp-1 would cause greater glucose-stimulated insulin secretion than equimolar administration into the jugular vein. |
2020-05-04 |
2023-08-13 |
rat |
| Muhamad Noor Alfarizal Kamarudin, Md Moklesur Rahman Sarker, Jin-Rong Zhou, Ishwar Parha. Metformin in colorectal cancer: molecular mechanism, preclinical and clinical aspects. Journal of experimental & clinical cancer research : CR. vol 38. issue 1. 2020-05-04. PMID:31831021. |
antidiabetic medications such as, insulin, sulfonylureas, dipeptyl peptidase (dpp) 4 inhibitors and glucose-dependent insulinotropic peptide (glp-1) analogues increased the additional risk of different cancers to diabetic patients. |
2020-05-04 |
2023-08-13 |
Not clear |
| Quinn Dufurrena, Nils Bäck, Richard E Mains, Louis Hodgson, Herbert Tanowitz, Prashant Mandela, Elizabeth Eipper, Regina Kuliawa. Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion. Journal of molecular endocrinology. 2020-05-01. PMID:30407917. |
glp-1 addition restored rac1 localization/activity and insulin secretion in the absence of kalirin, thereby assigning kalirin's participation to stimulatory glucose signaling. |
2020-05-01 |
2023-08-13 |
Not clear |
| Tanya M Halliday, Sarit Polsky, Jonathan A Schoen, Kristina T Legget, Jason R Tregellas, Kayla M Williamson, Marc-Andre Cornie. Comparison of surgical versus diet-induced weight loss on appetite regulation and metabolic health outcomes. Physiological reports. vol 7. issue 7. 2020-04-30. PMID:30927343. |
appetite (hunger, satiety, and prospective food consumption [pfc]), appetite-related hormones, and metabolites (ghrelin, pyy, glp-1, insulin, glucose, free fatty acids [ffa], and triglycerides [tg]) were measured in the fasting state and every 30 min for 180 min following breakfast. |
2020-04-30 |
2023-08-13 |
human |
| Guojun Chen, Jicheng Yu, Zhen G. Glucose-Responsive Microneedle Patches for Diabetes Treatment. Journal of diabetes science and technology. vol 13. issue 1. 2020-04-24. PMID:29848105. |
antidiabetic therapeutics, including insulin as well as glucagon-like peptide 1 (glp-1) and its analogs, are essential for people with diabetes to regulate their blood glucose levels. |
2020-04-24 |
2023-08-13 |
Not clear |
| Barnaby Hunt, Samuel J P Malkin, Robert G J Moes, Eline L Huisman, Tom Vandebrouck, Bruce H R Wolffenbutte. Once-weekly semaglutide for patients with type 2 diabetes: a cost-effectiveness analysis in the Netherlands. BMJ open diabetes research & care. vol 7. issue 1. 2020-04-22. PMID:31641522. |
the present analysis assessed the cost-effectiveness of once-weekly semaglutide (a novel glucagon-like peptide-1 (glp-1) receptor agonist) versus insulin glargine u100 (the most commonly used basal insulin) and versus dulaglutide (an alternative once-weekly glp-1 receptor agonist), from a societal perspective in the netherlands. |
2020-04-22 |
2023-08-13 |
Not clear |
| Trevor Steward, Romina Miranda-Olivos, Carles Soriano-Mas, Fernando Fernández-Arand. Neuroendocrinological mechanisms underlying impulsive and compulsive behaviors in obesity: a narrative review of fMRI studies. Reviews in endocrine & metabolic disorders. vol 20. issue 3. 2020-04-20. PMID:31654260. |
research on the associations between brain response with neuroendocrine factors, such as insulin, peptide yy (pyy), leptin, ghrelin and glucagon-like peptide 1 (glp-1), will be reviewed. |
2020-04-20 |
2023-08-13 |
Not clear |
| Neng Tine Kartinah, Fadilah Fadilah, Ermita Ilyas Ibrahim, Yuliana Suryat. The Potential of BioMed research international. vol 2019. 2020-04-20. PMID:31828140. |
the potential of glucagon-like peptide 1 (glp-1) hormone is an incretin hormone that is secreted in the ileum and plays a role in the pancreas to increase insulin secretion, stimulate proliferation, and prevent pancreatic |
2020-04-20 |
2023-08-13 |
Not clear |
| Catherine K Y Chan, Hrvoje Fabek, Rebecca C Mollard, Peter J H Jones, Mehmet C Tulbek, Ravindra N Chibbar, Manu P Gangola, Bharathi Raja Ramadoss, Diana Sánchez-Hernández, G Harvey Anderso. Faba bean protein flours added to pasta reduce post-ingestion glycaemia, and increase satiety, protein content and quality. Food & function. vol 10. issue 11. 2020-04-16. PMID:31670336. |
post-consumption measurements included postprandial blood glucose, insulin, c-peptide, glp-1 and pyy, and subjective appetite, over 120 min. |
2020-04-16 |
2023-08-13 |
human |
| Pierre Larraufie, Geoffrey P Roberts, Anne K McGavigan, Richard G Kay, Joyce Li, Andrew Leiter, Audrey Melvin, Emma K Biggs, Peter Ravn, Kathleen Davy, David C Hornigold, Giles S H Yeo, Richard H Hardwick, Frank Reimann, Fiona M Gribbl. Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery. Cell reports. vol 26. issue 6. 2020-04-06. PMID:30726726. |
elevated post-prandial concentrations of glucagon-like peptide 1 (glp-1), peptide yy (pyy), and insulin are widely reported, but the importance of glp-1 in post-bariatric physiology remains debated. |
2020-04-06 |
2023-08-13 |
mouse |
| Pierre Larraufie, Geoffrey P Roberts, Anne K McGavigan, Richard G Kay, Joyce Li, Andrew Leiter, Audrey Melvin, Emma K Biggs, Peter Ravn, Kathleen Davy, David C Hornigold, Giles S H Yeo, Richard H Hardwick, Frank Reimann, Fiona M Gribbl. Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery. Cell reports. vol 26. issue 6. 2020-04-06. PMID:30726726. |
here, we show that glp-1 is a major driver of insulin secretion after bariatric surgery, as demonstrated by blocking glp-1 receptors (glp1rs) post-gastrectomy in lean humans using exendin-9 or in mice using an anti-glp1r antibody. |
2020-04-06 |
2023-08-13 |
mouse |
| Pierre Larraufie, Geoffrey P Roberts, Anne K McGavigan, Richard G Kay, Joyce Li, Andrew Leiter, Audrey Melvin, Emma K Biggs, Peter Ravn, Kathleen Davy, David C Hornigold, Giles S H Yeo, Richard H Hardwick, Frank Reimann, Fiona M Gribbl. Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery. Cell reports. vol 26. issue 6. 2020-04-06. PMID:30726726. |
we conclude that increased glp-1 secretion after bariatric surgery arises from rapid nutrient delivery to the distal gut and is a key driver of enhanced insulin secretion. |
2020-04-06 |
2023-08-13 |
mouse |
| Swati Prakash, Uddipak Rai, Ramoji Kosuru, Vinod Tiwari, Sanjay Sing. Amelioration of diet-induced metabolic syndrome and fatty liver with sitagliptin via regulation of adipose tissue inflammation and hepatic Adiponectin/AMPK levels in mice. Biochimie. vol 168. 2020-04-06. PMID:31715215. |
fasting serum insulin (fsi), glucagon-like peptide-1 (glp-1), adipokines (adiponectin and leptin), serum lipid profile, hepatic lipid content, and white adipose tissue inflammation were assessed. |
2020-04-06 |
2023-08-13 |
mouse |
| Dengni Lai, Mingyong Huang, Lingyan Zhao, Yan Tian, Yong Li, Dongpo Liu, Yanyang Wu, Fangming Den. Delphinidin-induced autophagy protects pancreatic β cells against apoptosis resulting from high-glucose stress via AMPK signaling pathway. Acta biochimica et biophysica Sinica. vol 51. issue 12. 2020-04-06. PMID:31781740. |
delphinidin, a member of the anthocyanin family, inhibits glucose absorption, increases glucagon-like peptide-1 (glp-1) secretion, and improves insulin secretion in diabetes. |
2020-04-06 |
2023-08-13 |
Not clear |
| Rachel A Elovaris, Amy T Hutchison, Kylie Lange, Michael Horowitz, Christine Feinle-Bisset, Natalie D Luscombe-Mars. Plasma Free Amino Acid Responses to Whey Protein and Their Relationships with Gastric Emptying, Blood Glucose- and Appetite-Regulatory Hormones and Energy Intake in Lean Healthy Men. Nutrients. vol 11. issue 10. 2020-03-25. PMID:31618863. |
gastric emptying, serum concentrations of aas, ghrelin, cholecystokinin (cck), glucagon-like-peptide 1 (glp-1), insulin, glucagon and blood glucose were measured before and after the drinks over 180 min. |
2020-03-25 |
2023-08-13 |
Not clear |