| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sachin L Badole, Pranita P Bagul, Sagar P Mahamuni, Rekha D Khose, Anuja C Joshi, Ganesh B Jangam, Arvindkumar E Ghule, Chandrashekhar G Raut, Vijay M Khedkar, Evans C Coutinh. Oral L-glutamine increases active GLP-1 (7-36) amide secretion and improves glycemic control in stretpozotocin-nicotinamide induced diabetic rats. Chemico-biological interactions. vol 203. issue 2. 2013-06-26. PMID:23466488. |
l-glutamine decreased plasma glucose, increased plasma and pancreatic insulin, increased plasma and colonic active glp-1 (7-36) amide secretion as well as decreased oxidative stress in streptozotocin-nicotinamide induced diabetic rats. |
2013-06-26 |
2023-08-12 |
rat |
| Ashley Therasse, Amisha Wallia, Mark E Molitc. Management of post-transplant diabetes. Current diabetes reports. vol 13. issue 1. 2013-06-19. PMID:23188594. |
sulfonylureas, metformin, dpp-4 inhibitors, glp-1 agonists, and insulin can be used in treatment, but when there is impaired kidney or hepatic function, special precautions are necessary. |
2013-06-19 |
2023-08-12 |
Not clear |
| Yuji Nakamura, Takanori Kanai, Keita Saeki, Miho Takabe, Junichiro Irie, Jun Miyoshi, Yohei Mikami, Toshiaki Teratani, Takahiro Suzuki, Naoteru Miyata, Tadakazu Hisamatsu, Nobuhiro Nakamoto, Yoshiyuki Yamagishi, Hajime Higuchi, Hirotoshi Ebinuma, Shigenari Hozawa, Hidetsugu Saito, Hiroshi Itoh, Toshifumi Hib. CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion. American journal of physiology. Gastrointestinal and liver physiology. vol 304. issue 8. 2013-06-17. PMID:23449669. |
ccr2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased glp-1 receptor expression and insulin secretion. |
2013-06-17 |
2023-08-12 |
mouse |
| Yuji Nakamura, Takanori Kanai, Keita Saeki, Miho Takabe, Junichiro Irie, Jun Miyoshi, Yohei Mikami, Toshiaki Teratani, Takahiro Suzuki, Naoteru Miyata, Tadakazu Hisamatsu, Nobuhiro Nakamoto, Yoshiyuki Yamagishi, Hajime Higuchi, Hirotoshi Ebinuma, Shigenari Hozawa, Hidetsugu Saito, Hiroshi Itoh, Toshifumi Hib. CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion. American journal of physiology. Gastrointestinal and liver physiology. vol 304. issue 8. 2013-06-17. PMID:23449669. |
glucagon-like peptide-1 (glp-1) promotes insulin release; however, the relationship between the glp-1 signal and chronic pancreatitis is not well understood. |
2013-06-17 |
2023-08-12 |
mouse |
| Yuji Nakamura, Takanori Kanai, Keita Saeki, Miho Takabe, Junichiro Irie, Jun Miyoshi, Yohei Mikami, Toshiaki Teratani, Takahiro Suzuki, Naoteru Miyata, Tadakazu Hisamatsu, Nobuhiro Nakamoto, Yoshiyuki Yamagishi, Hajime Higuchi, Hirotoshi Ebinuma, Shigenari Hozawa, Hidetsugu Saito, Hiroshi Itoh, Toshifumi Hib. CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion. American journal of physiology. Gastrointestinal and liver physiology. vol 304. issue 8. 2013-06-17. PMID:23449669. |
collectively, the ccr2/ccl2 axis-mediated cd11b(+)-cell migration to the pancreas is critically involved in chronic pancreatitis-mediated hyperglycemia through the modulation of glp-1 receptor expression and insulin secretion. |
2013-06-17 |
2023-08-12 |
mouse |
| Lawrence Blonde, Danial E Baker, Stephen N Davis, Robert E Ratne. New concepts in diabetes: how multihormonal regulation can improve glycemic control. Journal of managed care pharmacy : JMCP. vol 10. issue 6 Suppl B. 2013-06-17. PMID:23570175. |
new research into the pathophysiology of diabetes indicates that multiple hormones--not just insulin and glucagon but amylin, glp-1 (a glucagon-like peptide), and others--are involved in the regulation of plasma glucose levels, providing insight into why even insulin is often ineffective in helping patient with diabetes achieve their glycemic goals. |
2013-06-17 |
2023-08-12 |
Not clear |
| Yuka Mitsuhashi, Daisuke Nagaoka, Karen E Bigley, Tomoshige Umeda, Kazuya Otsuji, John E Baue. Metabolic and Hormonal Alterations with Diacylglycerol and Low Glycemic Index Starch during Canine Weight Loss. ISRN veterinary science. vol 2012. 2013-06-14. PMID:23762590. |
at weeks 1 and 8, fasting plasma insulin, glucose, nonesterified fatty acid (nefa), glucose-dependent insulinotropic polypeptide (gip), and glucagon-like peptide-1 (glp-1) were determined. |
2013-06-14 |
2023-08-12 |
Not clear |
| Yuka Mitsuhashi, Daisuke Nagaoka, Karen E Bigley, Tomoshige Umeda, Kazuya Otsuji, John E Baue. Metabolic and Hormonal Alterations with Diacylglycerol and Low Glycemic Index Starch during Canine Weight Loss. ISRN veterinary science. vol 2012. 2013-06-14. PMID:23762590. |
weight loss did not affect fasting insulin, glucose, and nefa, but fasting gip increased and glp-1 decreased. |
2013-06-14 |
2023-08-12 |
Not clear |
| Laura Pala, Anna Pezzatini, Ilaria Dicembrini, Silvia Ciani, Stefania Gelmini, Barbara Gabriella Vannelli, Barbara Cresci, Edoardo Mannucci, Carlo Maria Rotell. Different modulation of dipeptidyl peptidase-4 activity between microvascular and macrovascular human endothelial cells. Acta diabetologica. vol 49 Suppl 1. 2013-06-13. PMID:20455069. |
in order to better elucidate the role of insulin sensitizers on the modulation of glp-1 circulating levels, dpp-4 activity and mrna expression were measured in cultured human aortic endothelial cells (haec) and human microvascular dermal endothelial cells (hmvec) exposed to high glucose, metformin and rosiglitazone. |
2013-06-13 |
2023-08-12 |
human |
| A I Duarte, E Candeias, S C Correia, R X Santos, C Carvalho, S Cardoso, A Plácido, M S Santos, C R Oliveira, P I Moreir. Crosstalk between diabetes and brain: glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration. Biochimica et biophysica acta. vol 1832. issue 4. 2013-06-13. PMID:23314196. |
in fact, several studies showed that, besides improving peripheral (and probably brain) insulin signaling, glp-1 analogs minimize cell loss and possibly rescue cognitive decline in models of ad, parkinson's (pd) or huntington's disease. |
2013-06-13 |
2023-08-12 |
Not clear |
| Kwang-Chul Kwon, Ramya Nityanandam, James S New, Henry Daniel. Oral delivery of bioencapsulated exendin-4 expressed in chloroplasts lowers blood glucose level in mice and stimulates insulin secretion in beta-TC6 cells. Plant biotechnology journal. vol 11. issue 1. 2013-06-11. PMID:23078126. |
glucagon-like peptide (glp-1) increases insulin secretion but is rapidly degraded (half-life: 2 min in circulation). |
2013-06-11 |
2023-08-12 |
mouse |
| Tongzhi Wu, Michelle J Bound, Scott D Standfield, Karen L Jones, Michael Horowitz, Christopher K Rayne. Effects of taurocholic acid on glycemic, glucagon-like peptide-1, and insulin responses to small intestinal glucose infusion in healthy humans. The Journal of clinical endocrinology and metabolism. vol 98. issue 4. 2013-06-11. PMID:23418316. |
in vitro and animal studies suggest that bile acids have the capacity to reduce blood glucose by stimulating glucagon-like peptide-1 (glp-1) and, thereby, insulin. |
2013-06-11 |
2023-08-12 |
Not clear |
| Sachin L Badole, Sagar P Mahamuni, Pranita P Bagul, Rekha D Khose, Anuja C Joshi, Arvindkumar E Ghule, Subhash L Bodhankar, Chandrashekhar G Raut, Vijay M Khedkar, Evans C Coutinho, Nilesh K Wag. Cycloart-23-ene-3β, 25-diol stimulates GLP-1 (7-36) amide secretion in streptozotocin-nicotinamide induced diabetic Sprague Dawley rats: a mechanistic approach. European journal of pharmacology. vol 698. issue 1-3. 2013-06-10. PMID:23117087. |
glycosylated haemoglobin, lipid profile, plasma and colonic active (glp-1) (7-36) amide, mrna expression of proglucagnon glp-1, plasma and pancreatic insulin, histology of pancreata as well as biomarkers of oxidative stress (superoxidase dismutase, reduced glutathione, malondialdehyde, glutathione peroxidase, glutathione s transferase) were measured after 8th week treatment. |
2013-06-10 |
2023-08-12 |
rat |
| Sachin L Badole, Sagar P Mahamuni, Pranita P Bagul, Rekha D Khose, Anuja C Joshi, Arvindkumar E Ghule, Subhash L Bodhankar, Chandrashekhar G Raut, Vijay M Khedkar, Evans C Coutinho, Nilesh K Wag. Cycloart-23-ene-3β, 25-diol stimulates GLP-1 (7-36) amide secretion in streptozotocin-nicotinamide induced diabetic Sprague Dawley rats: a mechanistic approach. European journal of pharmacology. vol 698. issue 1-3. 2013-06-10. PMID:23117087. |
in acute study, active glp-1 (7-36) amide release, plasma glucose and insulin were measured during oral glucose tolerance test. |
2013-06-10 |
2023-08-12 |
rat |
| Sachin L Badole, Sagar P Mahamuni, Pranita P Bagul, Rekha D Khose, Anuja C Joshi, Arvindkumar E Ghule, Subhash L Bodhankar, Chandrashekhar G Raut, Vijay M Khedkar, Evans C Coutinho, Nilesh K Wag. Cycloart-23-ene-3β, 25-diol stimulates GLP-1 (7-36) amide secretion in streptozotocin-nicotinamide induced diabetic Sprague Dawley rats: a mechanistic approach. European journal of pharmacology. vol 698. issue 1-3. 2013-06-10. PMID:23117087. |
it decreased plasma glucose level, increased plasma and pancreatic insulin level as well as increased plasma and colonic active glp-1 (7-36) amide secretion in streptozotocin-nicotinamide induced diabetic sprague dawley rats. |
2013-06-10 |
2023-08-12 |
rat |
| H K J Gonnissen, T Hulshof, M S Westerterp-Planteng. Chronobiology, endocrinology, and energy- and food-reward homeostasis. Obesity reviews : an official journal of the International Association for the Study of Obesity. vol 14. issue 5. 2013-06-06. PMID:23387351. |
a good sleep hygiene, together with circadian alignment of food intake, a regular meal frequency, and attention for protein intake or diets, contributes in curing sleep abnormalities and overweight/obesity features by preventing overeating; normalizing substrate oxidation, stress, insulin and glucose metabolism including homa-ir index, and leptin, glp-1 concentrations, lipid metabolism, appetite, energy expenditure and substrate oxidation; and normalizing food reward. |
2013-06-06 |
2023-08-12 |
Not clear |
| Giuseppe Derosa, Pamela Maffiol. GLP-1 agonists exenatide and liraglutide: a review about their safety and efficacy. Current clinical pharmacology. vol 7. issue 3. 2013-06-03. PMID:22432846. |
in particular exenatide and liraglutide have structural similarity and bind to the glp-1 receptor, displaying a similar broad range of activities relevant to improving glycemic control, including stimulation of insulin secretion and reduction of glucagon secretion, both in a glucose-dependent manner. |
2013-06-03 |
2023-08-12 |
Not clear |
| Shauna S Runchey, Liisa M Valsta, Yvonne Schwarz, Chiachi Wang, Xiaoling Song, Johanna W Lampe, Marian L Neuhouse. Effect of low- and high-glycemic load on circulating incretins in a randomized clinical trial. Metabolism: clinical and experimental. vol 62. issue 2. 2013-06-03. PMID:22959497. |
we aimed to assess effects of dietary glycemic load on fasting and post-prandial glucose, insulin and incretin (i.e., glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1)) concentrations and to examine for effect modification by adiposity. |
2013-06-03 |
2023-08-12 |
Not clear |
| S ThanThan, Y Asada, T Saito, K Ochiiwa, H Zhao, S Yannaing, H Kuwayam. Oxyntomodulin attenuates exendin-4-induced hypoglycemia in cattle. Domestic animal endocrinology. vol 44. issue 2. 2013-06-03. PMID:23122871. |
in experiment 1, we initially assessed the effects of intravenous (iv) bolus injection of 0, 0.25, 1, and 2 μg/kg body weight (bw) of ex-4, glp-1, and oxm on insulin and glucose concentrations in 3-mo-old intact male holstein calves. |
2013-06-03 |
2023-08-12 |
cattle |
| Yunli Yu, Xinting Wang, Can Liu, Dan Yao, Mengyue Hu, Jia Li, Nan Hu, Li Liu, Xiaodong Li. Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats. Toxicology and applied pharmacology. vol 266. issue 3. 2013-05-29. PMID:23200776. |
oral administration of gatifloxacin (100 mg/kg/day and 200 mg/kg/day) for 3 and 12 days led to marked elevation of glp-1 levels, accompanied by significant decrease in insulin levels and increase in plasma glucose. |
2013-05-29 |
2023-08-12 |
rat |