| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kristine Færch, Signe S Torekov, Dorte Vistisen, Nanna B Johansen, Daniel R Witte, Anna Jonsson, Oluf Pedersen, Torben Hansen, Torsten Lauritzen, Annelli Sandbæk, Jens Juul Holst, Marit E Jørgense. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study. Diabetes. vol 64. issue 7. 2015-09-15. PMID:25677912. |
circulating concentrations of glucose, insulin, and glp-1 during an oral glucose tolerance test (ogtt) were analyzed in individuals with normal glucose tolerance (ngt) (n = 774), prediabetes (n = 525), or screen-detected type 2 diabetes (n = 163) who attended the danish addition-pro study (n = 1,462). |
2015-09-15 |
2023-08-13 |
Not clear |
| Kristine Færch, Signe S Torekov, Dorte Vistisen, Nanna B Johansen, Daniel R Witte, Anna Jonsson, Oluf Pedersen, Torben Hansen, Torsten Lauritzen, Annelli Sandbæk, Jens Juul Holst, Marit E Jørgense. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study. Diabetes. vol 64. issue 7. 2015-09-15. PMID:25677912. |
higher glp-1 responses were associated with better insulin sensitivity and β-cell function, older age, and lesser degree of obesity. |
2015-09-15 |
2023-08-13 |
Not clear |
| Eva Tomas, Violeta Stanojevic, Karen McManus, Ashok Khatri, Paul Everill, William W Bachovchin, Joel F Habene. GLP-1(32-36)amide Pentapeptide Increases Basal Energy Expenditure and Inhibits Weight Gain in Obese Mice. Diabetes. vol 64. issue 7. 2015-09-15. PMID:25858562. |
here we report the identification of a pentapeptide, glp-1(32-36)amide (lvkgramide), derived from the glucoincretin hormone glp-1, that increases basal energy expenditure and curtails the development of obesity, insulin resistance, diabetes, and hepatic steatosis in diet-induced obese mice. |
2015-09-15 |
2023-08-13 |
mouse |
| D D Miceli, M F Cabrera Blatter, M F Gallelli, O P Pignataro, V A Castill. Involvement of glucagon-like peptide 1 in the glucose homeostasis regulation in obese and pituitary-dependent hyperadrenocorticism affected dogs. Research in veterinary science. vol 97. issue 2. 2015-09-10. PMID:25128418. |
the incretin glucagon-like peptide 1 (glp-1) enhances insulin secretion. |
2015-09-10 |
2023-08-13 |
Not clear |
| D D Miceli, M F Cabrera Blatter, M F Gallelli, O P Pignataro, V A Castill. Involvement of glucagon-like peptide 1 in the glucose homeostasis regulation in obese and pituitary-dependent hyperadrenocorticism affected dogs. Research in veterinary science. vol 97. issue 2. 2015-09-10. PMID:25128418. |
the aim of this study was to assess glp-1, glucose and insulin concentrations, homeostatic model assessment (homa insulin sensitivity and homa β-cell function) in dogs with pituitary-dependent hyperadrenocorticism (pdh), and compare these values with those in normal and obese dogs. |
2015-09-10 |
2023-08-13 |
Not clear |
| D D Miceli, M F Cabrera Blatter, M F Gallelli, O P Pignataro, V A Castill. Involvement of glucagon-like peptide 1 in the glucose homeostasis regulation in obese and pituitary-dependent hyperadrenocorticism affected dogs. Research in veterinary science. vol 97. issue 2. 2015-09-10. PMID:25128418. |
the oral glucose tolerance test was performed and the glucose, glp-1 and insulin concentrations were evaluated at baseline, and after 15, 30, 60 and 120 minutes. |
2015-09-10 |
2023-08-13 |
Not clear |
| D D Miceli, M F Cabrera Blatter, M F Gallelli, O P Pignataro, V A Castill. Involvement of glucagon-like peptide 1 in the glucose homeostasis regulation in obese and pituitary-dependent hyperadrenocorticism affected dogs. Research in veterinary science. vol 97. issue 2. 2015-09-10. PMID:25128418. |
both basal concentration and those corresponding to the subsequent times, for glucose, glp-1 and insulin, were statistically elevated in pdh dogs compared to the other groups. |
2015-09-10 |
2023-08-13 |
Not clear |
| D D Miceli, M F Cabrera Blatter, M F Gallelli, O P Pignataro, V A Castill. Involvement of glucagon-like peptide 1 in the glucose homeostasis regulation in obese and pituitary-dependent hyperadrenocorticism affected dogs. Research in veterinary science. vol 97. issue 2. 2015-09-10. PMID:25128418. |
insulin followed a similar behaviour together with variations of glp-1. |
2015-09-10 |
2023-08-13 |
Not clear |
| Kartikkumar Navinchandra Patel, Amit Arvind Joharapurkar, Vishal Patel, Samadhan Govind Kshirsagar, Rajesh Bahekar, Brijesh Kumar Srivastava, Mukul R Jai. Cannabinoid receptor 1 antagonist treatment induces glucagon release and shows an additive therapeutic effect with GLP-1 agonist in diet-induced obese mice. Canadian journal of physiology and pharmacology. vol 92. issue 12. 2015-08-31. PMID:25361428. |
a stable analog of glucagon-like peptide 1 (glp-1), exendin-4 improves glucose-stimulated insulin secretion in pancreas, and reduces appetite through activation of glp-1 receptors in the central nervous system and liver. |
2015-08-31 |
2023-08-13 |
mouse |
| Kartikkumar Navinchandra Patel, Amit Arvind Joharapurkar, Vishal Patel, Samadhan Govind Kshirsagar, Rajesh Bahekar, Brijesh Kumar Srivastava, Mukul R Jai. Cannabinoid receptor 1 antagonist treatment induces glucagon release and shows an additive therapeutic effect with GLP-1 agonist in diet-induced obese mice. Canadian journal of physiology and pharmacology. vol 92. issue 12. 2015-08-31. PMID:25361428. |
we hypothesized that the insulin secretagogue effect of glp-1 agonist exendin-4 may synergize with the insulin-sensitizing action of rimonabant. |
2015-08-31 |
2023-08-13 |
mouse |
| D Ripken, N van der Wielen, J van der Meulen, T Schuurman, R F Witkamp, H F J Hendriks, S J Koopman. Cholecystokinin regulates satiation independently of the abdominal vagal nerve in a pig model of total subdiaphragmatic vagotomy. Physiology & behavior. vol 139. 2015-08-31. PMID:25449395. |
furthermore, effects of vagotomy on preprandial and postprandial acetaminophen absorption, glucose, insulin, glp-1 and cck plasma concentrations were investigated. |
2015-08-31 |
2023-08-13 |
Not clear |
| D Ripken, N van der Wielen, J van der Meulen, T Schuurman, R F Witkamp, H F J Hendriks, S J Koopman. Cholecystokinin regulates satiation independently of the abdominal vagal nerve in a pig model of total subdiaphragmatic vagotomy. Physiology & behavior. vol 139. 2015-08-31. PMID:25449395. |
vagotomy decreased acetaminophen absorption and changed glucose, insulin, cck and glp-1 concentrations indicating a delay in gastric emptying. |
2015-08-31 |
2023-08-13 |
Not clear |
| Benedikt A Aulinger, Torsten P Vahl, Hilary E Wilson-Pérez, Ron L Prigeon, David A D'Alessi. β-Cell Sensitivity to GLP-1 in Healthy Humans Is Variable and Proportional to Insulin Sensitivity. The Journal of clinical endocrinology and metabolism. vol 100. issue 6. 2015-08-31. PMID:25825945. |
β-cell sensitivity to glp-1 in healthy humans is variable and proportional to insulin sensitivity. |
2015-08-31 |
2023-08-13 |
Not clear |
| Benedikt A Aulinger, Torsten P Vahl, Hilary E Wilson-Pérez, Ron L Prigeon, David A D'Alessi. β-Cell Sensitivity to GLP-1 in Healthy Humans Is Variable and Proportional to Insulin Sensitivity. The Journal of clinical endocrinology and metabolism. vol 100. issue 6. 2015-08-31. PMID:25825945. |
infusion of glp-1 increases insulin secretion in both diabetic and nondiabetic humans. |
2015-08-31 |
2023-08-13 |
Not clear |
| Svetlana Beglinger, Anne Christin Meyer-Gerspach, Steffi Graf, Urs Zumsteg, Jürgen Drewe, Christoph Beglinger, Jean-Pierre Gutzwille. Effect of a test meal on meal responses of satiation hormones and their association to insulin resistance in obese adolescents. Obesity (Silver Spring, Md.). vol 22. issue 9. 2015-08-26. PMID:24930697. |
to (i) examine glucagon-like peptide 1 (glp-1), amylin, ghrelin, and glucagon responses to a meal in obese adolescents and to (ii) test which gi peptides are associated with insulin resistance are presented. |
2015-08-26 |
2023-08-13 |
Not clear |
| Bernard Charbonnel, Monica Bertolini, Francisco J Tinahones, Manuel Puig Domingo, Melanie Davie. Lixisenatide plus basal insulin in patients with type 2 diabetes mellitus: a meta-analysis. Journal of diabetes and its complications. vol 28. issue 6. 2015-08-24. PMID:25130920. |
the efficacy of the once-daily prandial glp-1 receptor agonist lixisenatide plus basal insulin in t2dm was assessed by pooling results of phase iii trials. |
2015-08-24 |
2023-08-13 |
Not clear |
| Injae Hwang, Yoon Jeong Park, Yeon-Ran Kim, Yo Na Kim, Sojeong Ka, Ho Young Lee, Je Kyung Seong, Yeong-Jae Seok, Jae Bum Ki. Alteration of gut microbiota by vancomycin and bacitracin improves insulin resistance via glucagon-like peptide 1 in diet-induced obesity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 29. issue 6. 2015-08-24. PMID:25713030. |
concomitantly, systemic glucose intolerance, hyperinsulinemia, and insulin resistance in dio were ameliorated via augmentation of glp-1 secretion (active form; 2.03-fold, total form; 5.09-fold) independently of obesity as compared with untreated dio controls. |
2015-08-24 |
2023-08-13 |
mouse |
| Injae Hwang, Yoon Jeong Park, Yeon-Ran Kim, Yo Na Kim, Sojeong Ka, Ho Young Lee, Je Kyung Seong, Yeong-Jae Seok, Jae Bum Ki. Alteration of gut microbiota by vancomycin and bacitracin improves insulin resistance via glucagon-like peptide 1 in diet-induced obesity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 29. issue 6. 2015-08-24. PMID:25713030. |
together, our data suggest that firmicutes and bacteroidetes potentially mediate insulin resistance through modulation of glp-1 secretion in obesity. |
2015-08-24 |
2023-08-13 |
mouse |
| Tara Ghazi, Linda Rink, Jennifer L Sherr, Kevan C Herol. Acute metabolic effects of exenatide in patients with type 1 diabetes with and without residual insulin to oral and intravenous glucose challenges. Diabetes care. vol 37. issue 1. 2015-08-18. PMID:23939544. |
glucose excursions, insulin secretion rates (isrs), and levels of glucagon, endogenous glp-1, and gastric inhibitory polypeptide were measured after the meal or glucose loads. |
2015-08-18 |
2023-08-12 |
Not clear |
| Etie S Moghiss. Treating patients with diabetes of long duration: GLP-1 receptor agonists and insulin in combination. The Journal of the American Osteopathic Association. vol 114. issue 5 Suppl 2. 2015-08-18. PMID:24769505. |
treating patients with diabetes of long duration: glp-1 receptor agonists and insulin in combination. |
2015-08-18 |
2023-08-13 |
Not clear |