| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Weihao Wang, Zhengxiang Huang, Lili Huang, Chunlu Tan, Wanlin Chen, Ferdinand Roelfsema, Chen Chen, Lixin Gu. Rotating Day and Night Disturb Growth Hormone Secretion Profiles, Body Energy Metabolism, and Insulin Levels in Mice. Neuroendocrinology. 2021-12-14. PMID:34348337. |
insulin and growth hormone (gh) - 2 vital metabolic regulatory hormones - regulate glucose, lipid, and energy metabolism. |
2021-12-14 |
2023-08-15 |
mouse |
| Weihao Wang, Zhengxiang Huang, Lili Huang, Chunlu Tan, Wanlin Chen, Ferdinand Roelfsema, Chen Chen, Lixin Gu. Rotating Day and Night Disturb Growth Hormone Secretion Profiles, Body Energy Metabolism, and Insulin Levels in Mice. Neuroendocrinology. 2021-12-14. PMID:34348337. |
shift of day and night affects the clock system and metabolism probably through altered insulin and gh secretion. |
2021-12-14 |
2023-08-15 |
mouse |
| Andrzej Bartke, Holly Brown-Bor. Mutations Affecting Mammalian Aging: GH and GHR vs IGF-1 and Insulin. Frontiers in genetics. vol 12. 2021-12-13. PMID:34899820. |
mutations affecting mammalian aging: gh and ghr vs igf-1 and insulin. |
2021-12-13 |
2023-08-13 |
Not clear |
| Mari C Vázquez-Borrego, Mercedes Del Rio-Moreno, Rhonda D Kinema. Towards Understanding the Direct and Indirect Actions of Growth Hormone in Controlling Hepatocyte Carbohydrate and Lipid Metabolism. Cells. vol 10. issue 10. 2021-12-11. PMID:34685512. |
gh acts through its gh receptor (ghr) to modulate the production and function of insulin-like growth factor 1 (igf1) and insulin. |
2021-12-11 |
2023-08-13 |
Not clear |
| Mari C Vázquez-Borrego, Mercedes Del Rio-Moreno, Rhonda D Kinema. Towards Understanding the Direct and Indirect Actions of Growth Hormone in Controlling Hepatocyte Carbohydrate and Lipid Metabolism. Cells. vol 10. issue 10. 2021-12-11. PMID:34685512. |
gh, igf1, and insulin act on multiple tissues to coordinate metabolic control in a context-specific manner. |
2021-12-11 |
2023-08-13 |
Not clear |
| Juan P López-Siguero, Maria J Martínez-Aedo, Jose Antonio Bermúdez de la Vega, Jordi Bosch-Muñoz, Alfonso M Lechuga-Sancho, Triana Villalobo. Growth hormone treatment does not to lead to insulin resistance nor excessive rise in IGF-1 levels, while improving height in patients small for gestational age A long-term observational study. Clinical endocrinology. 2021-12-09. PMID:34882803. |
in children born small for gestational age (sga), the relationship between growth hormone (gh) treatment and insulin resistance (ir) has only been investigated for a short period, necessitating a longer observation period. |
2021-12-09 |
2023-08-13 |
Not clear |
| Jukkrapong Pinyo, Hiroshi Hara, Tohru Hir. Diet-induced obesity enhances postprandial glucagon-like peptide-1 secretion in Wistar rats, but not in diabetic Goto-Kakizaki rats. The British journal of nutrition. vol 126. issue 4. 2021-12-07. PMID:33143769. |
although gk rats fed the hfs diet (gh) had higher glycaemic responses than gk rats fed the control diet (gc), these groups had similar postprandial glp-1 and insulin responses throughout the study. |
2021-12-07 |
2023-08-13 |
rat |
| Zhengxiang Huang, Xuehan Lu, Lili Huang, Yang Chen, Chunhong Zhang, Johannes D Veldhuis, Chen Che. Suppression of hyperinsulinemia restores growth hormone secretion and metabolism in obese mice. The Journal of endocrinology. vol 250. issue 3. 2021-11-22. PMID:34156345. |
the well-balanced secretion between insulin and growth hormone (gh) is essential in regulating substrate metabolism, energy metabolism, and body composition. |
2021-11-22 |
2023-08-13 |
mouse |
| Zhengxiang Huang, Xuehan Lu, Lili Huang, Yang Chen, Chunhong Zhang, Johannes D Veldhuis, Chen Che. Suppression of hyperinsulinemia restores growth hormone secretion and metabolism in obese mice. The Journal of endocrinology. vol 250. issue 3. 2021-11-22. PMID:34156345. |
high insulin and low gh levels are often observed in obesity, contributing to reduced energy expenditure and further fat accumulation. |
2021-11-22 |
2023-08-13 |
mouse |
| Marya Dushar, Jędrzej Nowaczyk, Beata Pyrżak, Hayane Akopyan, Robert Śmigiel, Anna Walczak, Małgorzata Rydzanicz, Rafał Płoski, Krzysztof Szczałub. Efficacy and safety of sirolimus therapy in familial hypoinsulinemic hypoglycemia caused by AKT2 mutation inherited from the mosaic father. European journal of medical genetics. vol 64. issue 12. 2021-11-22. PMID:34673243. |
the boys, aged 1 and 14, who had severe non-insulin-dependent hypoketotic hypoglycemia and a typical dysmorphism, were admitted to endocrinology department for the analysis of their metabolic parameters: lipids, lactate, ammonia, glucose, insulin, c-peptide, and hormones (gh, igf1, igfbp3, tsh, ft4, cortisol, acth) before and during treatment with sirolimus. |
2021-11-22 |
2023-08-13 |
Not clear |
| Disa L Hatfield, William J Kraemer, Jeff S Volek, Bradley C Nindl, Lydia K Caldwell, Jakob L Vingren, Robert U Newton, Keijo Häkkinen, Elaine C Lee, Carl M Maresh, Wesley C Hyme. Hormonal stress responses of growth hormone and insulin-like growth factor-I in highly resistance trained women and men. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 59. 2021-11-18. PMID:34118743. |
blood samples were obtained pre-exercise, after 3 sets, and then immediately after exercise (ip), 5, 15, 30, and 70 min post-exercise for determination of blood lactate (hla), and plasma glucose, insulin, cortisol, and gh. |
2021-11-18 |
2023-08-13 |
human |
| Valentina Gasco, Alice Ferrero, Alessandro Bisceglia, Nunzia Prencipe, Valeria Cambria, Fabio Bioletto, Ezio Ghigo, Mauro Maccario, Silvia Grottol. The Cut-off Limits of Growth Hormone Response to the Insulin Tolerance Test Related to Body Mass Index for the Diagnosis of Adult Growth Hormone Deficiency. Neuroendocrinology. vol 111. issue 5. 2021-11-17. PMID:32335555. |
the diagnosis of growth hormone deficiency (ghd) in adults is based on a reduced gh response to provocative tests, such as the insulin tolerance test (itt) and the gh-releasing hormone (ghrh) + arginine (arg) test. |
2021-11-17 |
2023-08-13 |
human |
| Akari Momozono, Akinori Hayashi, Koji Takano, Masayoshi Shichir. The effectiveness of growth hormone replacement on energy expenditure and body composition in patients with adult growth hormone deficiency. Endocrine journal. vol 68. issue 4. 2021-11-17. PMID:33361693. |
gh replacement therapy significantly increased the serum insulin growth factor-1 levels after 4, 8, and 12 months. |
2021-11-17 |
2023-08-13 |
Not clear |
| Mikiko Koizumi, Ayako Konishi, Yuri Etani, Shinobu Ida, Masanobu Kawa. Circulating insulin-like growth factor 1 levels are reduced in very young children with Prader-Willi syndrome independent of anthropometric parameters and nutritional status. Clinical endocrinology. 2021-11-09. PMID:34750859. |
insulin growth factor-1 (igf-1) is used to evaluate growth hormone (gh) sufficiency and is decreased in children with prader-willi syndrome (pws). |
2021-11-09 |
2023-08-13 |
human |
| Shawn A Hallett, Wanida Ono, Noriaki On. The hypertrophic chondrocyte: To be or not to be. Histology and histopathology. 2021-11-03. PMID:34137454. |
this process is delicately regulated by major signaling pathways and their target genes, including growth hormone (gh), insulin growth factor-1 (igf-1), indian hedgehog (ihh), parathyroid hormone-related protein (pthrp), bone morphogenetic proteins (bmps), sex determining region y-box 9 (sox9), runt-related transcription factors (runx) and fibroblast growth factor receptors (fgfrs). |
2021-11-03 |
2023-08-13 |
Not clear |
| Astrid J Hjelholt, Evelina Charidemou, Julian L Griffin, Steen B Pedersen, Anders Gudiksen, Henriette Pilegaard, Niels Jessen, Niels Møller, Jens O L Jørgense. Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2 × 2 factorial, randomised, crossover study in human individuals. Diabetologia. vol 63. issue 12. 2021-11-01. PMID:32945898. |
growth hormone (gh) causes insulin resistance that is linked to lipolysis, but the underlying mechanisms are unclear. |
2021-11-01 |
2023-08-13 |
human |
| A V Vitebskaya, E A Pisareva, A V Popovic. [Comparative study of glucagon and insulin tests for diagnostics of secondary adrenal insufficiency and growth hormone deficiency in children and adolescents]. Problemy endokrinologii. vol 66. issue 6. 2021-10-27. PMID:33481367. |
russian consensus on diagnostics and treatment of hypopituitarism in children and adolescences recommends to measure gh and cortisol concentrations in every time-point of insulin test (it). |
2021-10-27 |
2023-08-13 |
Not clear |
| Katja Trobec, Stephan von Haehling, Stefan D Anker, Mitja Lainsca. Growth hormone, insulin-like growth factor 1, and insulin signaling-a pharmacological target in body wasting and cachexia. Journal of cachexia, sarcopenia and muscle. vol 2. issue 4. 2021-10-21. PMID:22207907. |
insulin, growth hormone (gh), and insulin-like growth factor 1 (igf-1) are involved in glucose, protein, and fat metabolism, which regulates body composition. |
2021-10-21 |
2023-08-12 |
Not clear |
| Katja Trobec, Stephan von Haehling, Stefan D Anker, Mitja Lainsca. Growth hormone, insulin-like growth factor 1, and insulin signaling-a pharmacological target in body wasting and cachexia. Journal of cachexia, sarcopenia and muscle. vol 2. issue 4. 2021-10-21. PMID:22207907. |
remodeled post-receptor insulin, gh, and igf-1 pathways constitute a potential target for pharmacological treatment in the setting of body wasting and cachexia. |
2021-10-21 |
2023-08-12 |
Not clear |
| Katja Trobec, Stephan von Haehling, Stefan D Anker, Mitja Lainsca. Growth hormone, insulin-like growth factor 1, and insulin signaling-a pharmacological target in body wasting and cachexia. Journal of cachexia, sarcopenia and muscle. vol 2. issue 4. 2021-10-21. PMID:22207907. |
peroxisome proliferator-activated receptor gamma agonists, drugs inhibiting angiotensin ii action (angiotensin ii antagonists and inhibitors of angiotensin-converting enzyme), and testosterone, which interfere with post-receptor pathways of insulin, gh, and igf-1, were investigated as pharmacological intervention targets and various clinically important implications were reported. |
2021-10-21 |
2023-08-12 |
Not clear |