| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyuzi Kamoi, Akira Shimatsu, Mai Kobayash. Is there an undiscovered neurocircuit for regulating GH secretion? -Pitfalls of GHRP-2 and ITT as GH provocative tests-. Endocrine journal. vol 57. issue 12. 2011-04-11. PMID:20953065. |
we examined the regulatory mechanism of gh secretion in an apparently healthy young man without decreased igf-1 concentration and nocturnal gh secretion, but who showed low responses to insulin tolerance (itt) and to ghrp-2 tests. |
2011-04-11 |
2023-08-12 |
human |
| Peter E Clayton, Indraneel Banerjee, Philip G Murray, Andrew G Reneha. Growth hormone, the insulin-like growth factor axis, insulin and cancer risk. Nature reviews. Endocrinology. vol 7. issue 1. 2011-04-06. PMID:20956999. |
growth hormone (gh), insulin-like growth factor (igf)-i and insulin have potent growth-promoting and anabolic actions. |
2011-04-06 |
2023-08-12 |
mouse |
| Peter E Clayton, Indraneel Banerjee, Philip G Murray, Andrew G Reneha. Growth hormone, the insulin-like growth factor axis, insulin and cancer risk. Nature reviews. Endocrinology. vol 7. issue 1. 2011-04-06. PMID:20956999. |
the evidence that gh, igf-i and insulin can promote and contribute to cancer progression comes from various sources, including transgenic and knockout mouse models and animal and human cell lines derived from cancers. |
2011-04-06 |
2023-08-12 |
mouse |
| Peter E Clayton, Indraneel Banerjee, Philip G Murray, Andrew G Reneha. Growth hormone, the insulin-like growth factor axis, insulin and cancer risk. Nature reviews. Endocrinology. vol 7. issue 1. 2011-04-06. PMID:20956999. |
although follow-up for the vast majority of these children does not yet extend beyond young adulthood, a slight increase in cancers in those with long-standing excess gh secretion (as seen in patients with acromegaly) and no overall increase in cancer with insulin treatment, have been observed. |
2011-04-06 |
2023-08-12 |
mouse |
| Sebastian J C M M Neggers, Aart J van der Lel. Modulation of glucocorticoid metabolism by the GH-IGF-I axis. Endocrine development. vol 20. 2011-03-31. PMID:21164271. |
growth hormone (gh) can generate insulin-like growth factor-i production, provided that the liver encounters portal insulin as a permissive factor that switches on the liver sensitivity for gh. |
2011-03-31 |
2023-08-12 |
Not clear |
| Sebastian J C M M Neggers, Aart J van der Lel. Modulation of glucocorticoid metabolism by the GH-IGF-I axis. Endocrine development. vol 20. 2011-03-31. PMID:21164271. |
also, acromegaly and obesity can be better understood when this effect of insulin on liver sensitivity for gh is taken into account. |
2011-03-31 |
2023-08-12 |
Not clear |
| Seongjoon Park, Toshimitsu Komatsu, Hiroko Hayashi, Lucas Siqueira Trindade, Haruyoshi Yamaza, Takuya Chiba, Isao Shimokaw. Divergent regulation of adipose tissue metabolism by calorie restriction and inhibition of growth hormone signaling. Experimental gerontology. vol 44. issue 10. 2011-03-14. PMID:19646410. |
calorie restriction (cr) and a reduced growth hormone (gh) signal affect insulin sensitivity and lifespan in mammals in a similar manner. |
2011-03-14 |
2023-08-12 |
rat |
| Seongjoon Park, Toshimitsu Komatsu, Hiroko Hayashi, Lucas Siqueira Trindade, Haruyoshi Yamaza, Takuya Chiba, Isao Shimokaw. Divergent regulation of adipose tissue metabolism by calorie restriction and inhibition of growth hormone signaling. Experimental gerontology. vol 44. issue 10. 2011-03-14. PMID:19646410. |
we investigated the effects of cr and moderate inhibition of gh on glucose-stimulated activation of insulin signaling and the expression of genes related to fat metabolism in white adipose tissue (wat) in rats. |
2011-03-14 |
2023-08-12 |
rat |
| Saira Waqar Lone, Yasir Naqi Khan, Farah Qamar, Irum Atta, Mohsina Noor Ibrahim, Jamal Raz. Safety of insulin tolerance test for the assessment of growth hormone deficiency in children. JPMA. The Journal of the Pakistan Medical Association. vol 61. issue 2. 2011-03-10. PMID:21375165. |
to determine the safety of insulin tolerance test (itt) for assessing growth hormone (gh) deficiency in children. |
2011-03-10 |
2023-08-12 |
Not clear |
| Géraldine Gontier, Martin Holzenberge. [IGF and insulin signaling pathways in longevity]. Biologie aujourd'hui. vol 204. issue 3. 2011-03-01. PMID:20950568. |
mutant mouse models affecting pituitary differentiation factors prop-1 or pit1, cognate receptors of gh, igf or insulin, or receptor substrates irs-1 or irs-2 showed that regulation of the somatotropic endocrine axis is pivotal for maintaining an equilibrium between growth, metabolism, oxidative stress defense and longevity. |
2011-03-01 |
2023-08-12 |
mouse |
| Stephen J Goodyear, Marcus Mottershead, Edmond Z H Sung, Ling S Wong, Philip G McTernan, Sudhesh Kumar, Chuka U Nwokol. Dysregulation of plasma ghrelin in alcoholic cirrhosis. Clinical endocrinology. vol 73. issue 3. 2011-02-28. PMID:20184601. |
plasma acylated and des-acyl ghrelin, gh, igf-1 and insulin were assayed by elisa. |
2011-02-28 |
2023-08-12 |
human |
| F Bagnoli, S Badii, M L Conte, M S Toti, C De Felice, C V Bellieni, G Borlini, B Tomasini, S Zan. [Influence of prolonged treatment with octreotide on GH, IGF I, insulin, ACTH, cortisol, T3, T4 and TSH secretion in a case of congenital chylothorax]. Minerva pediatrica. vol 62. issue 4. 2011-02-18. PMID:20940674. |
[influence of prolonged treatment with octreotide on gh, igf i, insulin, acth, cortisol, t3, t4 and tsh secretion in a case of congenital chylothorax]. |
2011-02-18 |
2023-08-12 |
Not clear |
| F Bagnoli, S Badii, M L Conte, M S Toti, C De Felice, C V Bellieni, G Borlini, B Tomasini, S Zan. [Influence of prolonged treatment with octreotide on GH, IGF I, insulin, ACTH, cortisol, T3, T4 and TSH secretion in a case of congenital chylothorax]. Minerva pediatrica. vol 62. issue 4. 2011-02-18. PMID:20940674. |
in no case the drug impact on insulin, gh and cortisol secretion in neonatal age has been investigated and only in one case the effect on thyroid hormones has been assessed. |
2011-02-18 |
2023-08-12 |
Not clear |
| Si-Zeng Chen, Zheng-Guo Qi. Combined treatment with GH, insulin, and indomethacin alleviates cancer cachexia in a mouse model. The Journal of endocrinology. vol 208. issue 2. 2011-02-17. PMID:21106721. |
combined treatment with gh, insulin, and indomethacin alleviates cancer cachexia in a mouse model. |
2011-02-17 |
2023-08-12 |
mouse |
| Si-Zeng Chen, Zheng-Guo Qi. Combined treatment with GH, insulin, and indomethacin alleviates cancer cachexia in a mouse model. The Journal of endocrinology. vol 208. issue 2. 2011-02-17. PMID:21106721. |
we have evaluated the effects of various treatments (gh, insulin (ins), indomethacin (ind), and all possible combinations) on cancer cachexia in a mouse model. |
2011-02-17 |
2023-08-12 |
mouse |
| Hamed A El-Khayat, Gamal S Aly, Hoda Y Tomoum, Rasha M Mamdouh, Abdelmalik K Al-Badani, Essam I Mohame. Growth hormone levels in children and adolescents with epilepsy. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. vol 14. issue 6. 2011-02-10. PMID:20227898. |
the aim of this study was to evaluate the effect of epilepsy and/or anti-epileptic drugs on the physical growth of patients with idiopathic epilepsy, as well as on the growth hormone (gh) and insulin growth factor-1 (igf-1) status in those patients. |
2011-02-10 |
2023-08-12 |
Not clear |
| Ravneet K Boparai, Oge Arum, Romesh Khardori, Andrzej Bartk. Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis. Biological chemistry. vol 391. issue 10. 2011-02-10. PMID:20707609. |
in contrast to its stimulatory effects on musculature, bone, and organ development, and its lipolytic effects, growth hormone (gh) opposes insulin effects on glucose metabolism. |
2011-02-10 |
2023-08-12 |
mouse |
| Ravneet K Boparai, Oge Arum, Romesh Khardori, Andrzej Bartk. Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis. Biological chemistry. vol 391. issue 10. 2011-02-10. PMID:20707609. |
chronic gh overexposure is thought to result in insulin insensitivity and decreased blood glucose homeostatic control. |
2011-02-10 |
2023-08-12 |
mouse |
| Ravneet K Boparai, Oge Arum, Romesh Khardori, Andrzej Bartk. Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis. Biological chemistry. vol 391. issue 10. 2011-02-10. PMID:20707609. |
yet, despite the importance of this concept for basic biology, as well as human conditions of gh excess or deficiency, no systematic assessment of the impact of gh over- expression on glucose homeostasis and insulin sensitivity has been conducted. |
2011-02-10 |
2023-08-12 |
mouse |
| Ravneet K Boparai, Oge Arum, Romesh Khardori, Andrzej Bartk. Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis. Biological chemistry. vol 391. issue 10. 2011-02-10. PMID:20707609. |
furthermore, increased glucose-stimulated insulin secretion, augmented insulin sensitivity, and muted gluconeogenesis were also observed in bovine gh overexpressing mice. |
2011-02-10 |
2023-08-12 |
mouse |