| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Horacio M Domené, Paula A Scaglia, Héctor G Jaspe. Deficiency of the insulin-like growth factor-binding protein acid-labile subunit (ALS) of the circulating ternary complex in children with short stature. Pediatric endocrinology reviews : PER. vol 7. issue 4. 2010-08-31. PMID:20679994. |
in the assessment of a child with short stature als deficiency should be considered in those patients presenting: 1) a normal response to gh stimulation test, 2) low igf-i levels associated with more profoundly reduced igfbp-3 levels, 3) a mild growth retardation, apparently out of proportion to the degree of igf-i and igfbp-3 deficits, 4) lack of response to an igf generation test and 5) insulin insensitivity. |
2010-08-31 |
2023-08-12 |
Not clear |
| Philippe Chanson, Anne Cailleux-Bounacer, Jean-Marc Kuhn, Georges Weryha, Olivier Chabre, Françoise Borson-Chazot, Séverine Dubois, Caroline Vincent-Dejean, Thierry Brue, Christine Fedou, Jean-Louis Bresson, Pierre Demolis, Jean-Claude Souberbiell. Comparative validation of the growth hormone-releasing hormone and arginine test for the diagnosis of adult growth hormone deficiency using a growth hormone assay conforming to recent international recommendations. The Journal of clinical endocrinology and metabolism. vol 95. issue 8. 2010-08-24. PMID:20484474. |
the ghrh plus arginine (ghrh+arg) test is a promising alternative to the insulin tolerance test (itt) for diagnosis of adult gh deficiency (aghd). |
2010-08-24 |
2023-08-12 |
Not clear |
| T Mikulski, A Ziemba, K Naza. Metabolic and hormonal responses to body carbohydrate store depletion followed by high or low carbohydrate meal in sedentary and physically active subjects. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 61. issue 2. 2010-08-03. PMID:20436220. |
during control session, after overnight fast oxygen uptake and co2 production were measured and blood glucose, free fatty acids (ffa), insulin (i), leptin (l), growth hormone (gh), testosterone (t), catecholamines, acth and cortisol were determined. |
2010-08-03 |
2023-08-12 |
human |
| Li Liang, Chao-chun Zou, Yun Li, Chun-lin Wang, You-jun Jiang, Guan-ping Dong, Jun-fen Fu, Xiu-min Wan. [Effect of recombinant human growth hormone on glucose metabolism in children with growth hormone deficiency]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 44. issue 9. 2010-07-30. PMID:17217656. |
the aim of this study was to investigate the effects of rhgh treatment on blood glucose and insulin metabolism in children with ghd and the relationship between growth hormone (gh) and glucose homeostasis. |
2010-07-30 |
2023-08-12 |
human |
| Katrien Koppo, Dominique Larrouy, Marie A Marques, Michel Berlan, Magda Bajzova, Jan Polak, Johan Van de Voorde, Jens Bülow, Max Lafontan, François Crampes, Dominique Langin, Vladimir Stich, Isabelle de Glisezinsk. Lipid mobilization in subcutaneous adipose tissue during exercise in lean and obese humans. Roles of insulin and natriuretic peptides. American journal of physiology. Endocrinology and metabolism. vol 299. issue 2. 2010-07-21. PMID:20484012. |
compared with the control condition, infusion of octreotide reduced plasma insulin levels in lean (from approximately 3.5 to 0.5 microu/ml) and in obese (from approximately 9 to 2 microu/ml), blunted the exercise-induced rise in plasma gh and epinephrine levels in both groups, and enhanced the exercise-induced natriuretic peptide (np) levels in lean but not in obese subjects. |
2010-07-21 |
2023-08-12 |
human |
| Tasha L Johnson, Brent A S Fujimoto, Rafaél Jiménez-Flores, Daniel G Peterso. Growth hormone alters lipid composition and increases the abundance of casein and lactalbumin mRNA in the MAC-T cell line. The Journal of dairy research. vol 77. issue 2. 2010-07-20. PMID:20380773. |
we tested the hypothesis that mac-t cells would respond directly to gh and that the response would include alterations to the lipid class distribution as well as to milk protein gene expression, leading to a more appropriate model for mammary cell function than treatment with dexamethasone, insulin and prolactin alone. |
2010-07-20 |
2023-08-12 |
cattle |
| Jill A Radack, Perrin C White, Beverley Adams-Huet, Jon D Ode. Stimulated growth hormone concentrations in obese pediatric patients with mild and severe insulin resistance: a pilot study. Journal of pediatric endocrinology & metabolism : JPEM. vol 23. issue 4. 2010-07-12. PMID:20583540. |
gh excess predisposes to insulin resistance (ir). |
2010-07-12 |
2023-08-12 |
Not clear |
| Marjeta Grzech, Maik Dahlhoff, Nadja Herbach, Felix A Habermann, Ingrid Renner-Müller, Rüdiger Wanke, Heinrich Flaswinkel, Eckhard Wolf, Marlon R Schneide. Specific transgene expression in mouse pancreatic beta-cells under the control of the porcine insulin promoter. Molecular and cellular endocrinology. vol 315. issue 1-2. 2010-07-05. PMID:19682540. |
to evaluate whether the full 5' untranslated region (utr) of the porcine insulin gene (ins) confers robust and specific expression in beta-cells we generated an expression cassette containing 1500bp of the porcine ins 5' utr and the 3' utr of the bovine growth hormone gene (gh). |
2010-07-05 |
2023-08-12 |
mouse |
| G Stennis Watson, Laura D Baker, Brenna A Cholerton, Kristoffer W Rhoads, George R Merriam, Gerard D Schellenberg, Sanjay Asthana, Monique Cherrier, Suzanne Craf. Effects of insulin and octreotide on memory and growth hormone in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 18. issue 3. 2010-06-30. PMID:19625744. |
this study tested the individual and interactive effects of insulin and octreotide on memory and plasma growth hormone (gh) levels in older adults. |
2010-06-30 |
2023-08-12 |
human |
| G Stennis Watson, Laura D Baker, Brenna A Cholerton, Kristoffer W Rhoads, George R Merriam, Gerard D Schellenberg, Sanjay Asthana, Monique Cherrier, Suzanne Craf. Effects of insulin and octreotide on memory and growth hormone in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 18. issue 3. 2010-06-30. PMID:19625744. |
finally, insulin may regulate gh levels during euglycemia. |
2010-06-30 |
2023-08-12 |
human |
| Eduardo Micmacher, Roberto P Assumpção, Renato G Redorat, Luciana D Spina, Ivan C Cruz, Carla A Silva, Mário Vaisman, Flávia Lúcia Conceiçã. Growth hormone secretion in response to glucagon stimulation test in healthy middle-aged men. Arquivos brasileiros de endocrinologia e metabologia. vol 53. issue 7. 2010-06-23. PMID:19942987. |
to investigate the growth hormone (gh) response to glucagon stimulation test (gst) in a population of healthy men over 50 years old in comparison to insulin tolerance test (itt), analysis of the spontaneous 24-hour gh profile and insulin-like growth factor 1 (igf-i). |
2010-06-23 |
2023-08-12 |
Not clear |
| Miriam Granado, Cristina García-Cáceres, Laura M Frago, Jesús Argente, Julie A Chowe. The positive effects of growth hormone-releasing peptide-6 on weight gain and fat mass accrual depend on the insulin/glucose status. Endocrinology. vol 151. issue 5. 2010-06-08. PMID:20219977. |
because insulin modulates the hypothalamic response to gh secretagogues and acts synergistically with ghrelin on lipogenesis in vitro, we analyzed whether insulin plays a role in the metabolic effects of ghrp-6 in vivo. |
2010-06-08 |
2023-08-12 |
rat |
| Ilonka Kreitschmann-Andermahr, Pablo Suarez, Rachel Jennings, Nina Evers, Georg Braban. GH/IGF-I regulation in obesity--mechanisms and practical consequences in children and adults. Hormone research in paediatrics. vol 73. issue 3. 2010-05-24. PMID:20197666. |
here we review the known and still speculative mechanisms underlying the inhibitory effects of obesity on gh secretion including peripheral factors like igf-i and insulin, as well as central hypothalamic/pituitary modulators. |
2010-05-24 |
2023-08-12 |
human |
| Yoshihisa Ohtani, Yosuke Kobayashi, Tatsuyuki Takahashi, Satoshi Haga, Mutsuo Takagi, Takanori Mashiko, Kazuo Katoh, Yoshiaki Obar. Effects of 5'-uridylic acid feeding on postprandial plasma concentrations of metabolites and metabolic hormones in pre-weaning goats. Animal science journal = Nihon chikusan Gakkaiho. vol 80. issue 5. 2010-05-20. PMID:20163622. |
analysis of blood samples taken in the morning of day 14 demonstrated that the feeding of milk replacer with ump abolished the significant changes in postprandial plasma glucose, nefa, gh and insulin concentrations induced by feeding of milk replacer alone, and demonstrated a tendency to increase igf-i levels. |
2010-05-20 |
2023-08-12 |
Not clear |
| Stanisław Niemczyk, Hanna Sikorska, Andrzej Wiecek, Ewa Zukowska-Szczechowska, Klaudia Załecka, Joanna Gorczyńska, Małgorzata Kubik, Beata Czerwieńska, Katarzyna Gosek, Johannes D Veldhuis, David A Wagner, Pierrette Gaudreau, Tiina Hakonen, Sam Wai Kit Kay, Taneli Jouhikainen, Franz Schaefe. A super-agonist of growth hormone-releasing hormone causes rapid improvement of nutritional status in patients with chronic kidney disease. Kidney international. vol 77. issue 5. 2010-05-19. PMID:20016461. |
chronic kidney disease is frequently associated with protein-energy wasting related to chronic inflammation and a resistance to anabolic hormones such as insulin and growth hormone (gh). |
2010-05-19 |
2023-08-12 |
Not clear |
| C Berg, T Meinel, H Lahner, K Mann, S Petersen. Recovery of pituitary function in the late-postoperative phase after pituitary surgery: results of dynamic testing in patients with pituitary disease by insulin tolerance test 3 and 12 months after surgery. European journal of endocrinology. vol 162. issue 5. 2010-05-07. PMID:20207728. |
the insulin tolerance test (itt) is considered the gold standard for assessment of gh and acth reserve in patients with pituitary disease following pituitary surgery and is usually performed after 6-12 weeks. |
2010-05-07 |
2023-08-12 |
Not clear |
| Fernando Cordido, Jesús Garcia-Buela, Susana Sangiao-Alvarellos, Teresa Martinez, Ovidio Vida. The decreased growth hormone response to growth hormone releasing hormone in obesity is associated to cardiometabolic risk factors. Mediators of inflammation. vol 2010. 2010-04-27. PMID:20150954. |
the aim of the present study was to evaluate the relationship between ghrh-induced gh secretion in obese premenopausal women and cardiovascular risk markers or insulin resistance. |
2010-04-27 |
2023-08-12 |
human |
| Fernando Cordido, Jesús Garcia-Buela, Susana Sangiao-Alvarellos, Teresa Martinez, Ovidio Vida. The decreased growth hormone response to growth hormone releasing hormone in obesity is associated to cardiometabolic risk factors. Mediators of inflammation. vol 2010. 2010-04-27. PMID:20150954. |
gh secretion, igf-i, serum cardiovascular risk markers, insulin, leptin, mid-waist and hip circumference, total body fat, and truncal fat were measured. |
2010-04-27 |
2023-08-12 |
human |
| Fernando Cordido, Jesús Garcia-Buela, Susana Sangiao-Alvarellos, Teresa Martinez, Ovidio Vida. The decreased growth hormone response to growth hormone releasing hormone in obesity is associated to cardiometabolic risk factors. Mediators of inflammation. vol 2010. 2010-04-27. PMID:20150954. |
peak gh secretion after stimulation was inversely associated with fasting insulin (r = -0.650, p = .012), homa-ir (r = -0.846, p = .001), total cholesterol (r = -0.532, p = .034), and ldl cholesterol (r = -0.692, p = .006) and positively associated with hdl cholesterol (r = 0.561, p = .037). |
2010-04-27 |
2023-08-12 |
human |
| Fernando Cordido, Jesús Garcia-Buela, Susana Sangiao-Alvarellos, Teresa Martinez, Ovidio Vida. The decreased growth hormone response to growth hormone releasing hormone in obesity is associated to cardiometabolic risk factors. Mediators of inflammation. vol 2010. 2010-04-27. PMID:20150954. |
these data strongly suggest a role for insulin resistance in the decreased gh secretion of obesity and that the blunted gh secretion of central obesity could be the pituitary expression of the metabolic syndrome. |
2010-04-27 |
2023-08-12 |
human |