| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J P Cappon, E Ipp, J A Brasel, D M Coope. Acute effects of high fat and high glucose meals on the growth hormone response to exercise. The Journal of clinical endocrinology and metabolism. vol 76. issue 6. 1993-07-01. PMID:8501145. |
we hypothesized that a single meal could attenuate the gh response to exercise by modulating substances like somatostatin, insulin, or glucose. |
1993-07-01 |
2023-08-12 |
Not clear |
| J C Bucuvalas, J A Horn, L Carlsson, W F Balistreri, S D Chernause. Growth hormone insensitivity associated with elevated circulating growth hormone-binding protein in children with Alagille syndrome and short stature. The Journal of clinical endocrinology and metabolism. vol 76. issue 6. 1993-07-01. PMID:8501153. |
in the control group, consisting of seven prepubertal children with gh deficiency, the predicted changes in response to rhgh in serum concentrations of igf-i and insulin, urea nitrogen, and urinary calcium excretion were observed. |
1993-07-01 |
2023-08-12 |
human |
| G R Foxcrof. Nutritional and lactational regulation of fertility in sows. Journal of reproduction and fertility. Supplement. vol 45. 1993-06-25. PMID:1304026. |
low plasma insulin, glucose and insulin-like growth factor 1 (igf-1), and high growth hormone (gh) and cortisol concentrations in sows in a catabolic state are all potentially involved. |
1993-06-25 |
2023-08-11 |
Not clear |
| C A Conover, M C Kiefe. Regulation and biological effect of endogenous insulin-like growth factor binding protein-5 in human osteoblastic cells. The Journal of clinical endocrinology and metabolism. vol 76. issue 5. 1993-06-23. PMID:7684391. |
treatment of u-2 cells with igf-i markedly increased medium levels of igfbp-5 in a concentration- and time-dependent manner; other skeletal regulatory factors (gh, insulin, pth, dexamethasone, beta-estradiol, 1,25-dihydroxyvitamin d3, transforming growth factor-beta) had no effect. |
1993-06-23 |
2023-08-12 |
human |
| J J Díez, A Gómez-Pa. [New physiological and pharmacological aspects of the growth hormone (I). The effects in adults]. Revista clinica espanola. vol 192. issue 6. 1993-06-23. PMID:8497724. |
glucose tolerance is decreased by gh, and this effect is accompanied by a decrease in peripheral utilization of glucose and an increase in insulin secretion. |
1993-06-23 |
2023-08-12 |
Not clear |
| J J Díez, A Gómez-Pa. [New physiological and pharmacological aspects of the growth hormone (I). The effects in adults]. Revista clinica espanola. vol 192. issue 6. 1993-06-23. PMID:8497724. |
gh behaves as a lipolytic hormone and gives rise to an increase in resistance to the lipogenetic action of insulin. |
1993-06-23 |
2023-08-12 |
Not clear |
| R Deyssig, H Frisch, W F Blum, T Waldhö. Effect of growth hormone treatment on hormonal parameters, body composition and strength in athletes. Acta endocrinologica. vol 128. issue 4. 1993-06-21. PMID:7684551. |
serum was assayed for gh, igf-i, igf-binding proteins, insulin and thyroxine before the onset of the study and at two-weekly intervals thereafter. |
1993-06-21 |
2023-08-12 |
human |
| D Prager, M M Weber, S Gebremedhin, S Melme. Interaction between insulin and thyroid hormone in rat pituitary tumour cells: insulin attenuates tri-iodothyronine-induced growth hormone mRNA levels. The Journal of endocrinology. vol 137. issue 1. 1993-06-16. PMID:8492068. |
insulin has previously been shown to inhibit basal and stimulated rat gh (rgh) secretion as well as basal gh transcription in rat pituitary cells. |
1993-06-16 |
2023-08-12 |
rat |
| D Prager, M M Weber, S Gebremedhin, S Melme. Interaction between insulin and thyroid hormone in rat pituitary tumour cells: insulin attenuates tri-iodothyronine-induced growth hormone mRNA levels. The Journal of endocrinology. vol 137. issue 1. 1993-06-16. PMID:8492068. |
the effect of physiological doses of insulin on tri-iodothyronine (t3)-stimulated gh mrna levels in rat pituitary tumour cells was therefore examined. |
1993-06-16 |
2023-08-12 |
rat |
| D Prager, M M Weber, S Gebremedhin, S Melme. Interaction between insulin and thyroid hormone in rat pituitary tumour cells: insulin attenuates tri-iodothyronine-induced growth hormone mRNA levels. The Journal of endocrinology. vol 137. issue 1. 1993-06-16. PMID:8492068. |
insulin (7 nmol/l) suppressed t3-stimulated gh mrna levels in gc and gh3 rat pituitary tumour cells by 58%. |
1993-06-16 |
2023-08-12 |
rat |
| D Prager, M M Weber, S Gebremedhin, S Melme. Interaction between insulin and thyroid hormone in rat pituitary tumour cells: insulin attenuates tri-iodothyronine-induced growth hormone mRNA levels. The Journal of endocrinology. vol 137. issue 1. 1993-06-16. PMID:8492068. |
this inhibitory effect of insulin on t3-stimulated gh mrna levels was already present after 24 h of treatment, and persisted for at least 48 h after insulin treatment was withdrawn. |
1993-06-16 |
2023-08-12 |
rat |
| D Prager, M M Weber, S Gebremedhin, S Melme. Interaction between insulin and thyroid hormone in rat pituitary tumour cells: insulin attenuates tri-iodothyronine-induced growth hormone mRNA levels. The Journal of endocrinology. vol 137. issue 1. 1993-06-16. PMID:8492068. |
the effect of insulin on gh mrna was selective, as rat prolactin mrna was stimulated by insulin and t3 in the same cells. |
1993-06-16 |
2023-08-12 |
rat |
| D Prager, M M Weber, S Gebremedhin, S Melme. Interaction between insulin and thyroid hormone in rat pituitary tumour cells: insulin attenuates tri-iodothyronine-induced growth hormone mRNA levels. The Journal of endocrinology. vol 137. issue 1. 1993-06-16. PMID:8492068. |
treatment of cells with cycloheximide (10 mumol/l) did not alter the attenuation of gh mrna levels by insulin, indicating that the insulin effect is independent of new protein synthesis. |
1993-06-16 |
2023-08-12 |
rat |
| D Prager, M M Weber, S Gebremedhin, S Melme. Interaction between insulin and thyroid hormone in rat pituitary tumour cells: insulin attenuates tri-iodothyronine-induced growth hormone mRNA levels. The Journal of endocrinology. vol 137. issue 1. 1993-06-16. PMID:8492068. |
when de-novo mrna synthesis was blocked with actinomycin d (4 micrograms/ml) for up to 7 h, an additional decrease in the relative amount of gh mrna levels was observed after 24, 48 and 72 h of insulin treatment, indicating that an effect of insulin on gh mrna stability is likely. |
1993-06-16 |
2023-08-12 |
rat |
| D Prager, M M Weber, S Gebremedhin, S Melme. Interaction between insulin and thyroid hormone in rat pituitary tumour cells: insulin attenuates tri-iodothyronine-induced growth hormone mRNA levels. The Journal of endocrinology. vol 137. issue 1. 1993-06-16. PMID:8492068. |
the results show that physiological doses of insulin selectively attenuate the stimulatory effect of t3 on gh mrna levels. |
1993-06-16 |
2023-08-12 |
rat |
| I M Chapman, R Kapoor, J O Willoughb. Endogenous catecholamines modulate growth hormone release in the conscious rat during hypoglycaemia but not in the basal state. Journal of neuroendocrinology. vol 5. issue 2. 1993-06-04. PMID:8097943. |
gh and prolactin secretory profiles were measured after giving rats 6 units/kg intravenous insulin. |
1993-06-04 |
2023-08-12 |
rat |
| I M Chapman, R Kapoor, J O Willoughb. Endogenous catecholamines modulate growth hormone release in the conscious rat during hypoglycaemia but not in the basal state. Journal of neuroendocrinology. vol 5. issue 2. 1993-06-04. PMID:8097943. |
intravenous idazoxan, prazosin, propranolol and cyproheptadine (doses as in first study) did not modify the blood glucose fall, but idazoxan produced a significant reduction of mean gh compared to insulin alone (4 +/- 1.1 ng/ml sem, idazoxan/insulin versus 16 +/- 5.6 ng/ml, saline/insulin). |
1993-06-04 |
2023-08-12 |
rat |
| J Fowelin, S Attvall, H von Schenck, B A Bengtsson, U Smith, I Lage. Effect of prolonged hyperglycemia on growth hormone levels and insulin sensitivity in insulin-dependent diabetes mellitus. Metabolism: clinical and experimental. vol 42. issue 3. 1993-06-04. PMID:8487660. |
this insulin resistance cannot be attributable to increased levels of insulin-antagonistic hormones, although an abnormal secretion pattern for gh was found. |
1993-06-04 |
2023-08-12 |
human |
| C M Foster, M Borondy, V Padmanabhan, J Schwartz, G B Kletter, N J Hopwood, I Z Beitin. Bioactivity of human growth hormone in serum: validation of an in vitro bioassay. Endocrinology. vol 132. issue 5. 1993-05-25. PMID:8477657. |
in the presence of 10 micrograms/liter insulin, 50 micrograms/liter insulin-like growth factor-1 did not alter the ability of gh to suppress lipid accumulation. |
1993-05-25 |
2023-08-12 |
human |
| C M Foster, M Borondy, V Padmanabhan, J Schwartz, G B Kletter, N J Hopwood, I Z Beitin. Bioactivity of human growth hormone in serum: validation of an in vitro bioassay. Endocrinology. vol 132. issue 5. 1993-05-25. PMID:8477657. |
pools of serum from prepubertal and pubertal boys and girls, subjects treated with arginine or insulin, a diabetic girl, and a boy with gigantism who had a serum gh content of 80 micrograms/liter by ria and 40 micrograms/liter by bioassay, produced dose response curves parallel to that of the gh standard curve. |
1993-05-25 |
2023-08-12 |
human |