| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Ng, R F Wolf, B Weksler, M F Brennan, M Bur. Growth hormone administration preserves lean body mass in sarcoma-bearing rats treated with doxorubicin. Cancer research. vol 53. issue 22. 1993-12-01. PMID:8221688. |
the dox-gh group had a significantly higher mean body weight, carcass weight, total fat free body mass, insulin growth factor 1, and gh plasma levels as compared to the dox group. |
1993-12-01 |
2023-08-12 |
rat |
| D I Jeoung, D L Allen, S Guller, V Yen, M Sonenber. Mitogenic and receptor activities of human growth hormone 108-129. The Journal of biological chemistry. vol 268. issue 30. 1993-12-01. PMID:8226761. |
no other gh peptides or insulin competed for binding of 125i-hgh 108-129. |
1993-12-01 |
2023-08-12 |
human |
| M Weise, D James, C H Leitner, K K Hartmann, H J Böhles, A Attanasi. Glucose metabolism in Ullrich Turner syndrome: long-term effects of therapy with human growth hormone. German Lilly UTS Study Group. Hormone research. vol 39. issue 1-2. 1993-11-10. PMID:8406337. |
results indicate that glucose homeostasis is maintained under gh therapy at the expense of a compensatory increase in insulin secretion which persists at higher gh dosages. |
1993-11-10 |
2023-08-12 |
human |
| A E Pontiroli, M G Perfetti, A C Andreotti, B Fattor, L D Monti, G Pozz. Metabolic effects of graded glucagon infusions in man: inhibition of glucagon, insulin, and somatostatin response to arginine. Metabolism: clinical and experimental. vol 42. issue 10. 1993-11-09. PMID:8105365. |
insulin inhibits its own release (autofeedback), and growth hormone (gh) inhibits the gh response to a variety of stimuli. |
1993-11-09 |
2023-08-12 |
Not clear |
| A E Pontiroli, M G Perfetti, A C Andreotti, B Fattor, L D Monti, G Pozz. Metabolic effects of graded glucagon infusions in man: inhibition of glucagon, insulin, and somatostatin response to arginine. Metabolism: clinical and experimental. vol 42. issue 10. 1993-11-09. PMID:8105365. |
all g infusions yielded stable and dose-related plasma irg levels, and the 4.0- and 8.0-ng/kg.min-1 g infusions decreased plasma free fatty acids (ffa) and blood glycerol and beta-oh-butyrate levels and elicited insulin (iri) release, and the 8.0-ng/kg.min-1 g infusion elicited gh release and increased blood glucose (bg) levels; somatostatin (srif) levels were not affected by g infusions. |
1993-11-09 |
2023-08-12 |
Not clear |
| V Nivet, J P Clot, X T Do, V Barrault, M Prélot, D Duran. Evidence that growth hormone stimulates protein kinase C activity in isolated rat hepatocytes. Metabolism: clinical and experimental. vol 42. issue 10. 1993-11-09. PMID:8412741. |
in this investigation, we directly examined the effects of gh relative to those of insulin on pkc activity in isolated rat hepatocytes. |
1993-11-09 |
2023-08-12 |
human |
| V Nivet, J P Clot, X T Do, V Barrault, M Prélot, D Duran. Evidence that growth hormone stimulates protein kinase C activity in isolated rat hepatocytes. Metabolism: clinical and experimental. vol 42. issue 10. 1993-11-09. PMID:8412741. |
the early effects of gh and insulin on pkc activity were additive in both the particulate and cytosolic fractions. |
1993-11-09 |
2023-08-12 |
human |
| V Nivet, J P Clot, X T Do, V Barrault, M Prélot, D Duran. Evidence that growth hormone stimulates protein kinase C activity in isolated rat hepatocytes. Metabolism: clinical and experimental. vol 42. issue 10. 1993-11-09. PMID:8412741. |
although the later effects of gh and insulin on pkc were quite different, both hormones rapidly activated pkc in isolated hepatocytes, suggesting that pkc might be involved in triggering the insulin-like actions of gh. |
1993-11-09 |
2023-08-12 |
human |
| J Saini, J Krieger, G Brandenberger, G Wittersheim, C Simon, M Folleniu. Continuous positive airway pressure treatment. Effects on growth hormone, insulin and glucose profiles in obstructive sleep apnea patients. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 25. issue 7. 1993-11-08. PMID:8406324. |
in this study nocturnal plasma and secretory gh profiles of osa patients were examined in relation to the quality and quantity of sleep, together with plasma glucose and insulin levels. |
1993-11-08 |
2023-08-12 |
human |
| J Saini, J Krieger, G Brandenberger, G Wittersheim, C Simon, M Folleniu. Continuous positive airway pressure treatment. Effects on growth hormone, insulin and glucose profiles in obstructive sleep apnea patients. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 25. issue 7. 1993-11-08. PMID:8406324. |
blood was collected continuously throughout each night and plasma gh, insulin and glucose profiles established in 10 min interval samples. |
1993-11-08 |
2023-08-12 |
human |
| K Plaut, M Ikeda, B K Vonderhaa. Role of growth hormone and insulin-like growth factor-I in mammary development. Endocrinology. vol 133. issue 4. 1993-11-03. PMID:8404627. |
igf-i did not substitute for prl, gh, or insulin in tissue maintenance. |
1993-11-03 |
2023-08-12 |
mouse |
| O Schmitz, L Orskov, S Lund, N Møller, J S Christiansen, H Orsko. Glucose metabolism in chronic renal failure with reference to GH treatment of uremic children. The Journal of pediatric endocrinology. vol 6. issue 1. 1993-10-19. PMID:8374690. |
if exogenous gh administration is added to the already marked uremic insulin resistance, insulin action may be severely disturbed and the secondary hyperinsulinism further magnified. |
1993-10-19 |
2023-08-12 |
human |
| J S Cook, R P Hoffman, M A Stene, J R Hanse. Effects of maturational stage on insulin sensitivity during puberty. The Journal of clinical endocrinology and metabolism. vol 77. issue 3. 1993-10-14. PMID:7690363. |
to determine 1) the time course of the decrease in insulin sensitivity in relationship to tanner stage of genital development, and 2) how this change relates to changes in gh secretion, insulin-like growth factor-i (igf-i), igf-binding protein-3, and gonadal steroid secretion, we studied 58 healthy children and adolescents (34 males and 24 females; age 7-15 yr) using overnight gh sampling and frequently sampled iv glucose tolerance tests. |
1993-10-14 |
2023-08-12 |
Not clear |
| C A Conover, J T Clarkson, L K Bal. Phorbol ester tumor promoters regulate insulin-like growth factor-binding protein-4 proteolysis. Endocrinology. vol 133. issue 3. 1993-10-06. PMID:7689953. |
in hfcm from cells treated with vehicle, gh, insulin, epidermal growth factor, steroid hormones, or forskolin, igf-ii induced the select loss of detectable igfbp-4 during the assay. |
1993-10-06 |
2023-08-12 |
human |
| E Muñoz-Martínez, M T Unzaga, B Jiménez Gancedo, J L Rely de Viña. [Blood glucose, insulin, GH, and amino acids in rats receiving 3 levels of dietary proteins]. Archivos latinoamericanos de nutricion. vol 42. issue 1. 1993-10-05. PMID:1308643. |
[blood glucose, insulin, gh, and amino acids in rats receiving 3 levels of dietary proteins]. |
1993-10-05 |
2023-08-11 |
rat |
| E Muñoz-Martínez, M T Unzaga, B Jiménez Gancedo, J L Rely de Viña. [Blood glucose, insulin, GH, and amino acids in rats receiving 3 levels of dietary proteins]. Archivos latinoamericanos de nutricion. vol 42. issue 1. 1993-10-05. PMID:1308643. |
the effect of dietary protein content on the variations in plasma insulin, gh, glucose and both gluconeogenic and branched-chain amino acids (bcaa) levels, was studied in wistar rats. |
1993-10-05 |
2023-08-11 |
rat |
| P I Shishko, R E Sadykova, P A Kovalev, B V Goncharo. [Insulin-like growth factor I in patients with newly detected insulin-dependent diabetes mellitus]. Problemy endokrinologii. vol 38. issue 1. 1993-10-04. PMID:1308586. |
in one month after intensified insulin infusion and three daily injections, the ratio is smoothed (igf-1 -- 320 + 20 during csii; 280 + 12 ng/ml during conventional insulin therapy and gh -- 10.0 + 1.2 for csii and 15.0 + 1.7 ng/ml for cit). |
1993-10-04 |
2023-08-11 |
human |
| M Weise, D James, K H Hartmann, D Reinhardt, C Leitner, H J Böhles, A Attanasi. Dose-dependent effect of growth hormone therapy on glucose metabolism in subjects with Turner syndrome. The German Lilly Ullrich-Turner Syndrome Study Group. Hormone research. vol 39 Suppl 2. 1993-09-30. PMID:8359785. |
so far, gh therapy has been given to patients with turner syndrome for up to 7 years without any significant changes having been reported in glycosylated haemoglobin (hba1c) values, unstimulated and stimulated oral glucose tolerance test (ogtt) blood glucose and serum insulin concentrations. |
1993-09-30 |
2023-08-12 |
human |
| M E Geffner, D Y Yeh, E M Landaw, M L Scott, E R Stiehm, Y J Bryson, V Israel. In vitro insulin-like growth factor-I, growth hormone, and insulin resistance occurs in symptomatic human immunodeficiency virus-1-infected children. Pediatric research. vol 34. issue 1. 1993-09-22. PMID:8356022. |
as an index of hormone sensitivity, we quantified in vitro colony formation of erythroid progenitor cells, isolated from peripheral blood of study subjects, in response to igf-i, growth hormone (gh), and insulin. |
1993-09-22 |
2023-08-12 |
human |
| M E Geffner, D Y Yeh, E M Landaw, M L Scott, E R Stiehm, Y J Bryson, V Israel. In vitro insulin-like growth factor-I, growth hormone, and insulin resistance occurs in symptomatic human immunodeficiency virus-1-infected children. Pediatric research. vol 34. issue 1. 1993-09-22. PMID:8356022. |
p2 subjects had a quantitative mean reduction in erythroid progenitor cells colony formation in response to igf-i of 32% compared with p1 subjects (p = 0.001 by analysis of variance) and 21% compared with controls (p = 0.006); in response to gh of 21% compared with controls (p = 0.015); and in response to insulin of 35% compared with p1 subjects (p = 0.038) and 34% compared with controls (p = 0.004). |
1993-09-22 |
2023-08-12 |
human |