| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K C Copeland, K S Nai. Acute growth hormone effects on amino acid and lipid metabolism. The Journal of clinical endocrinology and metabolism. vol 78. issue 5. 1994-06-08. PMID:8175957. |
control subjects received replacement doses of insulin, glucagon, and gh for the entire 7-h study period, whereas gh subjects received an identical protocol, except for an increased dose of gh sufficient to increase serum concentrations into the high-physiological range (12-20 ng/ml) for the final 3.5 h of the study (p < 0.001). |
1994-06-08 |
2023-08-12 |
human |
| P Bang, K Brismar, R G Rosenfeld, K Hal. Fasting affects serum insulin-like growth factors (IGFs) and IGF-binding proteins differently in patients with noninsulin-dependent diabetes mellitus versus healthy nonobese and obese subjects. The Journal of clinical endocrinology and metabolism. vol 78. issue 4. 1994-05-19. PMID:7512573. |
in the present study we have 1) assessed how differences in insulin and gh status between obese patients with noninsulin-dependent diabetes mellitus (niddm) and healthy obese (ob) and nonobese (nob) subjects are associated with different responses of insulin-like growth factors (igfs) and igf-binding proteins (igfbps) to fasting, and 2) determined whether the igf-i response to fasting in healthy subjects is secondary to changes in igfbp-3. |
1994-05-19 |
2023-08-12 |
human |
| P Bang, K Brismar, R G Rosenfeld, K Hal. Fasting affects serum insulin-like growth factors (IGFs) and IGF-binding proteins differently in patients with noninsulin-dependent diabetes mellitus versus healthy nonobese and obese subjects. The Journal of clinical endocrinology and metabolism. vol 78. issue 4. 1994-05-19. PMID:7512573. |
insulin-resistant niddm patients, with high basal glucose and insulin, normal igfbp-1, and low gh, had decreased prefasting serum igf-i concentrations, similar to the values in fasted body mass index- and age-matched ob subjects. |
1994-05-19 |
2023-08-12 |
human |
| P Bang, K Brismar, R G Rosenfeld, K Hal. Fasting affects serum insulin-like growth factors (IGFs) and IGF-binding proteins differently in patients with noninsulin-dependent diabetes mellitus versus healthy nonobese and obese subjects. The Journal of clinical endocrinology and metabolism. vol 78. issue 4. 1994-05-19. PMID:7512573. |
in conclusion, 1) differences in gh status and modulation of gh induction of igf-i by insulin resistance could contribute to low basal igf-i levels and lack of a igf-i response to fasting in patients with niddm; and 2) the turnover rate of igf-i in serum, which is largely determined by igfbp-3, is not likely to be altered by short term fasting, suggesting that the decrease in serum igf-i concentrations is a result of decreased igf-i production. |
1994-05-19 |
2023-08-12 |
human |
| D M Hoffman, A J O'Sullivan, R C Baxter, K K H. Diagnosis of growth-hormone deficiency in adults. Lancet (London, England). vol 343. issue 8905. 1994-05-19. PMID:7512681. |
we have evaluated the relative diagnostic merits of measuring peak gh response to insulin-induced hypoglycaemia (insulin tolerance test), mean 24 h gh concentration derived from 20 min sampling, serum insulin-like growth factor i (igf-i) concentrations, and serum igf binding protein 3 (igfbp-3) concentrations. |
1994-05-19 |
2023-08-12 |
human |
| B C Villafuerte, B L Koop, C I Pao, L Gu, G G Birdsong, L S Phillip. Coculture of primary rat hepatocytes and nonparenchymal cells permits expression of insulin-like growth factor binding protein-3 in vitro. Endocrinology. vol 134. issue 5. 1994-05-16. PMID:7512496. |
expression and secretion of igfbp-3 were hormonally responsive and strongly correlated (r = 0.79; p < 0.001), with 2- to 3-fold stimulation by added insulin or igf-i (both p < 0.05), but not by added gh alone. |
1994-05-16 |
2023-08-12 |
rat |
| B C Villafuerte, B L Koop, C I Pao, L Gu, G G Birdsong, L S Phillip. Coculture of primary rat hepatocytes and nonparenchymal cells permits expression of insulin-like growth factor binding protein-3 in vitro. Endocrinology. vol 134. issue 5. 1994-05-16. PMID:7512496. |
our findings suggest that gh may act indirectly to promote igfbp-3 generation in vivo via increasing both the secretion of insulin and the hepatic production of igf-i; in patients with diabetes mellitus, reduced circulating levels of igfbp-3 despite high levels of gh may result from both insulin deficiency and inadequate hepatic production of igf-i. |
1994-05-16 |
2023-08-12 |
rat |
| V Insler, A Barash, Z Shoham, R Koistinen, M Seppala, M Hen, B Lunenfeld, Z Zadi. Overnight secretion pattern of growth hormone, sex hormone binding globulin, insulin-like growth factor-1 and its binding protein in obese and non-obese women with polycystic ovarian disease. Israel journal of medical sciences. vol 30. issue 1. 1994-04-28. PMID:7511134. |
the levels of gh, lh, sex hormone binding globulin (shbg) and insulin-like growth factor binding protein-1 (igfbp-1) were significantly lower and insulin levels considerably higher in obese pcod women as compared to their non-obese counterparts. |
1994-04-28 |
2023-08-12 |
Not clear |
| V Insler, A Barash, Z Shoham, R Koistinen, M Seppala, M Hen, B Lunenfeld, Z Zadi. Overnight secretion pattern of growth hormone, sex hormone binding globulin, insulin-like growth factor-1 and its binding protein in obese and non-obese women with polycystic ovarian disease. Israel journal of medical sciences. vol 30. issue 1. 1994-04-28. PMID:7511134. |
blood samples were collected every 20 min over a period of 8 h, starting at 23:00 h. twenty-four samples were collected from each patient and examined in one batch for gh, igf-1, igfbp-1, shbg and insulin. |
1994-04-28 |
2023-08-12 |
Not clear |
| K S Lam, R W Pang, E D Janus, A W Kung, C C Wan. Serum apolipoprotein(a) correlates with growth hormone levels in Chinese patients with acromegaly. Atherosclerosis. vol 104. issue 1-2. 1994-04-28. PMID:8141841. |
there were significant reductions in serum gh (f = 7.30; p < 0.01), insulin growth factor 1 (igf1) (f = 31.4, p < 0.001) and insulin (f = 4.57; p < 0.05) concentrations. |
1994-04-28 |
2023-08-12 |
Not clear |
| K S Lam, R W Pang, E D Janus, A W Kung, C C Wan. Serum apolipoprotein(a) correlates with growth hormone levels in Chinese patients with acromegaly. Atherosclerosis. vol 104. issue 1-2. 1994-04-28. PMID:8141841. |
apo(a) levels correlated with serum gh (r = 0.450; p < 0.01) but showed no correlation with basal insulin concentrations. |
1994-04-28 |
2023-08-12 |
Not clear |
| J Fan, P E Molina, M C Gelato, C H Lan. Differential tissue regulation of insulin-like growth factor-I content and binding proteins after endotoxin. Endocrinology. vol 134. issue 4. 1994-04-26. PMID:7511091. |
lps-induced changes in plasma and tissue igfbp-3 were not regulated by changes in gh, and changes in insulin could not explain the alterations in igfbp-1 and -2. |
1994-04-26 |
2023-08-12 |
rat |
| M H Rasmussen, J Frystyk, T Andersen, L Breum, J S Christiansen, J Hilste. The impact of obesity, fat distribution, and energy restriction on insulin-like growth factor-1 (IGF-1), IGF-binding protein-3, insulin, and growth hormone. Metabolism: clinical and experimental. vol 43. issue 3. 1994-04-26. PMID:7511202. |
in 51 females and nine males having a body mass index (bmi) between 27 and 39 kg/m2, relationships between serum igf-1, igf-binding protein-3 (igfbp-3), insulin, growth hormone (gh), blood glucose, and anthropometric measurements of body fat were examined. |
1994-04-26 |
2023-08-12 |
Not clear |
| C R Baumrucker, J W Blu. Effects of dietary recombinant human insulin-like growth factor-I on concentrations of hormones and growth factors in the blood of newborn calves. The Journal of endocrinology. vol 140. issue 1. 1994-04-25. PMID:8138748. |
radioimmunoassays for insulin, prolactin, igf-i, igf-ii, gh, l-thyroxine, 3,5,3'-l-tri-iodothyroline and cortisol were conducted. |
1994-04-25 |
2023-08-12 |
human |
| J O Johansson, K Landin, L Tengborn, T Rosén, B A Bengtsso. High fibrinogen and plasminogen activator inhibitor activity in growth hormone-deficient adults. Arteriosclerosis and thrombosis : a journal of vascular biology. vol 14. issue 3. 1994-04-12. PMID:8123648. |
plasminogen activator inhibitor (pai-1) activity, fibrinogen, insulin, blood lipid, and blood pressure levels were studied in 20 gh-deficient adults (10 men, 10 women) 50 +/- 11 years old with routine hormone replacement therapy (except gh) and compared with 20 healthy control subjects matched for sex, age, and body mass index. |
1994-04-12 |
2023-08-12 |
human |
| H Kimata, A Yoshid. Differential effect of growth hormone and insulin-like growth factor-I, insulin-like growth factor-II, and insulin on Ig production and growth in human plasma cells. Blood. vol 83. issue 6. 1994-04-12. PMID:8123847. |
the effect of human growth hormone (gh) and insulin-like growth factor-i (igf-i), igf-ii, and insulin on human plasma cell responses was studied. |
1994-04-12 |
2023-08-12 |
human |
| J P Desborough, R A Griffin, C M Moore, J M Burrin, G M Hal. Growth hormone secretion in response to surgery. Effects of cholinergic blockade and octreotide. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 25. issue 12. 1994-04-07. PMID:8119670. |
cholinergic blockade markedly reduces the growth hormone (gh) response to most stimuli, with the exception of insulin induced hypoglycaemia. |
1994-04-07 |
2023-08-12 |
Not clear |
| J P Desborough, R A Griffin, C M Moore, J M Burrin, G M Hal. Growth hormone secretion in response to surgery. Effects of cholinergic blockade and octreotide. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 25. issue 12. 1994-04-07. PMID:8119670. |
thus surgery is similar to insulin induced hypoglycaemia poglycaemia in that the gh response is not decreased by cholinergic blockade. |
1994-04-07 |
2023-08-12 |
Not clear |
| C Duan, E M Plisetskay. Nutritional regulation of insulin-like growth factor-I mRNA expression in salmon tissues. The Journal of endocrinology. vol 139. issue 2. 1994-03-11. PMID:8308460. |
to understand the endocrine mechanism underlying the retarded growth in starved fish better, we investigated the effect of food deprivation and refeeding on circulating levels of gh and insulin, as well as insulin-like growth factor-i (igf-i) mrna expression in different tissues of juvenile coho salmon (oncorhynchus kisutch). |
1994-03-11 |
2023-08-12 |
Not clear |
| C Duan, E M Plisetskay. Nutritional regulation of insulin-like growth factor-I mRNA expression in salmon tissues. The Journal of endocrinology. vol 139. issue 2. 1994-03-11. PMID:8308460. |
no difference in circulating insulin or glucose levels were found between starved and fed fish, whereas starvation increased the plasma gh levels. |
1994-03-11 |
2023-08-12 |
Not clear |