| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rohan K Henry, Ram K Meno. Type 2 Diabetes Mellitus, a Sequel of Untreated Childhood Onset Growth Hormone Deficiency Developing in a 17-Year-Old Patient. Case reports in endocrinology. vol 2018. 2020-10-01. PMID:30473891. |
by extension, since hepatic insulin resistance (ir) is key to fl and type 2 diabetes mellitus (t2dm), gh then may ameliorate the ir of t2dm. |
2020-10-01 |
2023-08-13 |
Not clear |
| Carmen Sydlik, Claudia Weissenbacher, Julia Roeb, Susanne Bechtold-Dalla Pozza, Heinrich Schmid. Evaluation of Changes in Insulin Sensitivity in Prepubertal Small for Gestational Age Children Treated with Growth Hormone. Indian journal of endocrinology and metabolism. vol 23. issue 1. 2020-10-01. PMID:31016147. |
although growth hormone (gh) therapy for children born small for gestational age (sga) has been approved for many years, there are still concerns about increasing their risk for insulin resistance and diabetes mellitus type 2. |
2020-10-01 |
2023-08-13 |
Not clear |
| Silvana Duran-Ortiz, Alison L Brittain, John J Kopchic. The impact of growth hormone on proteomic profiles: a review of mouse and adult human studies. Clinical proteomics. vol 14. 2020-09-30. PMID:28670222. |
growth hormone (gh) is a protein that is known to stimulate postnatal growth, counter regulate insulin's action and induce expression of insulin-like growth factor-1. |
2020-09-30 |
2023-08-13 |
mouse |
| Andrzej Bartk. Somatic growth, aging, and longevity. NPJ aging and mechanisms of disease. vol 3. 2020-09-30. PMID:28970944. |
mechanisms linking gh, somatic growth, adult body size, aging, and lifespan likely involve target of rapamycin (tor), particularly one of its signaling complexes, mtorc1, as well as various adjustments in mitochondrial function, energy metabolism, thermogenesis, inflammation, and insulin signaling. |
2020-09-30 |
2023-08-13 |
mouse |
| Timothy B Legare, Oteni Hamilton, Sarah Dhannoon, Sayed Al. Non-Islet Cell Tumor Hypoglycemia: A Rare Cause of Hypoglycemia in Pulmonary Sarcomatoid Cancer. Cureus. vol 9. issue 12. 2020-09-30. PMID:29492361. |
laboratory studies during subsequent hypoglycemic events measured his insulin-like growth factor-i (igf-i) at 51 ng/ml, insulin-like growth factor-ii (igf-ii) at 290 ng/ml, growth hormone (gh) at 0.6 ng/ml, c-peptide at 0.16 ng/ml (low), and insulin levels at <1 uiu/ml. |
2020-09-30 |
2023-08-13 |
human |
| A B Abderrahman, F Rhibi, N Ouerghi, A C Hackney, A Saeidi, H Zouha. Effects of Recovery Mode during High Intensity Interval Training on Glucoregulatory Hormones and Glucose Metabolism in Response to Maximal Exercise. Journal of athletic enhancement. vol 7. issue 3. 2020-09-30. PMID:30191154. |
plasma catecholamines, glucose, insulin, growth hormone (gh) and cortisol were determined at rest, at the end of mgt, after 10 and 30 min of recovery. |
2020-09-30 |
2023-08-13 |
human |
| Alessandro Ciresi, Valentina Guarnotta, Daniela Campo, Carla Giordan. Hepatic Steatosis Index in Acromegaly: Correlation with Insulin Resistance Regardless of the Disease Control. International journal of endocrinology. vol 2018. 2020-09-30. PMID:30662461. |
in acromegaly, both lipotoxicity secondary to gh excess and insulin resistance have a significant impact on the liver. |
2020-09-30 |
2023-08-13 |
Not clear |
| Maria A Abrantes, Arwin M Valencia, Fayez Bany-Mohammed, Jacob V Aranda, Kay D Beharr. Combined antenatal and postnatal steroid effects on fetal and postnatal growth, and neurological outcomes in neonatal rats. American journal of translational research. vol 11. issue 3. 2020-09-30. PMID:30972194. |
igf-i, gh and insulin levels were elevated at all ages with dexamethasone. |
2020-09-30 |
2023-08-13 |
rat |
| Maria Kohek, Cassia Leme, Izabel T Nakamura, Suzimara A De Oliveira, Valeria Lando, Berenice B Mendonc. Effects of EDTA and Sodium Citrate on hormone measurements by fluorometric (FIA) and immunofluorometric (IFMA) methods. BMC clinical pathology. vol 2. issue 1. 2020-09-29. PMID:12033989. |
samples were analyzed in automatized equipment autodelfiatrade mark (perkin elmer brazil, wallac, finland) for the following hormones: luteinizing hormone (lh), follicle stimulating homone (fsh), prolactin (prl), growth hormone (gh), sex hormone binding globulin (shbg), thyroid stimulating hormone (tsh), insulin, c peptide, total t3, total t4, free t4, estradiol, progesterone, testosterone, and cortisol. |
2020-09-29 |
2023-08-12 |
Not clear |
| Maria Kohek, Cassia Leme, Izabel T Nakamura, Suzimara A De Oliveira, Valeria Lando, Berenice B Mendonc. Effects of EDTA and Sodium Citrate on hormone measurements by fluorometric (FIA) and immunofluorometric (IFMA) methods. BMC clinical pathology. vol 2. issue 1. 2020-09-29. PMID:12033989. |
results from gh, tsh, insulin, c peptide, shbg, total t3, total t4, estradiol, testosterone, cortisol, and progesterone were significant different between serum and edta-treated samples groups. |
2020-09-29 |
2023-08-12 |
Not clear |
| Alfredo Manzano-García, Mohammed Gamal-Eltrabil. A new role of growth hormone and insulin growth factor receptor type 1 in neonatal inflammatory nociception. Pain reports. vol 2. issue 4. 2020-09-29. PMID:29392223. |
growth hormone (gh) and insulin growth factor 1 (igf1) are implicated in nociceptive processing; it has been reported that the latter participates in neonatal inflammatory nociception. |
2020-09-29 |
2023-08-13 |
mouse |
| Yun Wang, He Zhang, Meng Cao, Lingfeng Kong, Xiaoli G. Analysis of the value and correlation of IGF-1 with GH and IGFBP-3 in the diagnosis of dwarfism. Experimental and therapeutic medicine. vol 17. issue 5. 2020-09-29. PMID:30988753. |
the basic information was recorded in detail; serum gh and igfbp-3 levels were measured using an arginine stimulation test and an insulin hypoglycemia stimulation test, respectively. |
2020-09-29 |
2023-08-13 |
human |
| Leila A Alenazy, Muhammad Javed, Hussien Elsiesy, Emad Raddaoui, Waleed K Al-Hamoud. Glycogenic Hepatopathy: A Rare Hepatic Complication of Poorly Controlled Type 1 DM. Case reports in medicine. vol 2020. 2020-09-28. PMID:32328105. |
the exact mechanism of gh remains unknown, but fluctuations in blood glucose and insulin levels play important roles in promoting glycogen accumulation. |
2020-09-28 |
2023-08-13 |
Not clear |
| Xubin Lu, Abdelaziz Adam Idriss Arbab, Zhipeng Zhang, Yongliang Fan, Ziyin Han, Qisong Gao, Yujia Sun, Zhangping Yan. Comparative Transcriptomic Analysis of the Pituitary Gland between Cattle Breeds Differing in Growth: Yunling Cattle and Leiqiong Cattle. Animals : an open access journal from MDPI. vol 10. issue 8. 2020-09-28. PMID:32722439. |
our study found that the contents of gh, igf, tsh, thyroxine, triiodothyronine, and insulin were significantly different between the two breeds, which was the main cause of the difference in growth; 175 genes were identified as differentially expressed genes (degs). |
2020-09-28 |
2023-08-13 |
cattle |
| Kevin C Corbit, Camella G Wilson, Dylan Lowe, Jennifer L Tran, Nicholas B Vera, Michelle Clasquin, Aras N Mattis, Ethan J Weis. Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma. JCI insight. vol 5. 2020-09-21. PMID:31393852. |
here, we report that aged mice lacking hepatocyte jak2 (jak2l), an obligate transducer of growth hormone (gh) signaling, spontaneously develop the full spectrum of phenotypes found in patients with metabolic liver disease, beginning with insulin resistance and lipodystrophy and manifesting as nafld, nash and even hcc, independent of dietary intervention. |
2020-09-21 |
2023-08-13 |
mouse |
| Erin Faught, Mathilakath M Vijaya. Glucocorticoid and mineralocorticoid receptor activation modulates postnatal growth. The Journal of endocrinology. vol 244. issue 2. 2020-09-18. PMID:31661673. |
the combined activation of mr and gr by cortisol also upregulated the gh and igf1 transcript abundance, and insulin expression compared to the wt. |
2020-09-18 |
2023-08-13 |
zebrafish |
| Mônica R Barrios, Viviane C Campos, Nalu T A Peres, Laís L de Oliveira, Rodrigo A Cazzaniga, Márcio B Santos, Murilo B Aires, Ricardo L L Silva, Aline Barreto, Hiro Goto, Roque P Almeida, Roberto Salvatori, Manuel H Aguiar-Oliveira, Amélia M R Jesu. Macrophages From Subjects With Isolated GH/IGF-I Deficiency Due to a GHRH Receptor Gene Mutation Are Less Prone to Infection by Frontiers in cellular and infection microbiology. vol 9. 2020-07-13. PMID:31544067. |
these subjects exhibit throughout the life very low levels of gh and its principal mediator, the insulin growth factor-i (igf-i). |
2020-07-13 |
2023-08-13 |
mouse |
| Gabriela Colon, Tatiana Saccon, Augusto Schneider, Marcelo B Cavalcante, Derek M Huffman, Darlene Berryman, Ed List, Yuji Ikeno, Nicolas Musi, Andrzej Bartke, John Kopchick, James L Kirkland, Tamara Tchkonia, Michal M Masterna. The enigmatic role of growth hormone in age-related diseases, cognition, and longevity. GeroScience. vol 41. issue 6. 2020-07-09. PMID:31485887. |
conversely, other studies found positive effects of gh deficiency including extended life span, improved cognitive function, resistance to diseases such as cancer and diabetes, and improved insulin sensitivity despite a higher fat percentage. |
2020-07-09 |
2023-08-13 |
Not clear |
| Alécia A Oliveira-Santos, Roberto Salvatori, Monica C Nogueira, Ana C Bueno, Cynthia S Barros-Oliveira, Ângela C G B Leal, Cindi G Marinho, Nayra P Damascena, Djane A Oliveira, Manuela A Melo, Carla R P Oliveira, Flavia O da Costa, Jéssica S S Dos Santos, Paula F C Santos, Viviane C Campos, Elenilde G Santos, Enaldo V Melo, Meirielly L A Barbosa, Ivina E S Rocha, Margaret de Castro, Manuel H Aguiar-Oliveir. Enteroendocrine Connections in Congenital Isolated GH Deficiency Due to a GHRH Receptor Gene Mutation. The Journal of clinical endocrinology and metabolism. vol 104. issue 7. 2020-06-01. PMID:30860584. |
gh and igf-1 are crucial for attainment of normal body size and regulation of food intake, nutrient storage, and insulin sensitivity. |
2020-06-01 |
2023-08-13 |
Not clear |
| Yuki Naito, Jun Mori, Jun Tazoe, Akimasa Tomida, Shigeki Yagyu, Hisakazu Nakajima, Tomoko Iehara, Kazunori Tatsuzawa, Tokuo Mukai, Hajime Hoso. Pituitary apoplexy after cardiac surgery in a 14-year-old girl with Carney complex: a case report. Endocrine journal. vol 66. issue 12. 2020-05-22. PMID:31484850. |
in contrast, insulin tolerance test showed gh deficiency. |
2020-05-22 |
2023-08-13 |
Not clear |