Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Guokun Yang, Beichen Chen, Caiyun Sun, Xi Yuan, Yazhou Zhang, Jingkai Qin, Wensheng L. Molecular identification of grouper Igfbp1 and its mRNA expression in primary hepatocytes under Gh and insulin. General and comparative endocrinology. vol 281. 2019-12-12. PMID:31176753. |
molecular identification of grouper igfbp1 and its mrna expression in primary hepatocytes under gh and insulin. |
2019-12-12 |
2023-08-13 |
Not clear |
Edward O List, Darlene E Berryman, Mathew Buchman, Elizabeth A Jensen, Kevin Funk, Silvana Duran-Ortiz, Yanrong Qian, Jonathan A Young, Julie Slyby, Savannah McKenna, John J Kopchic. GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity. Endocrinology. vol 160. issue 7. 2019-12-06. PMID:31099824. |
gh knockout mice have increased subcutaneous adipose tissue with decreased fibrosis and enhanced insulin sensitivity. |
2019-12-06 |
2023-08-13 |
mouse |
Edward O List, Darlene E Berryman, Mathew Buchman, Elizabeth A Jensen, Kevin Funk, Silvana Duran-Ortiz, Yanrong Qian, Jonathan A Young, Julie Slyby, Savannah McKenna, John J Kopchic. GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity. Endocrinology. vol 160. issue 7. 2019-12-06. PMID:31099824. |
finally, we demonstrate that gh-/- mice are responsive to gh treatment, as shown by changes to serum igf-1 levels; body length, weight, and composition; and insulin sensitivity. |
2019-12-06 |
2023-08-13 |
mouse |
Shuang Liang, Dejian Zhang, Jianhong Qi, Xiaobo Song, Jiang Xu. Reduced peak stimulated growth hormone is associated with hyperuricemia in obese children and adolescents. Scientific reports. vol 8. issue 1. 2019-11-25. PMID:29785038. |
these data indicate that lower peak gh is positively associated with hyperuricemia in obese children and adolescents without known hypothalamic/pituitary disease after controlling bmi and insulin resistance, as well as other cardiometabolic risk factors. |
2019-11-25 |
2023-08-13 |
human |
Pontirol. Peptide hormones: Review of current and emerging uses by nasal delivery. Advanced drug delivery reviews. vol 29. issue 1-2. 2019-11-20. PMID:10837581. |
luteinizing hormone releasing hormone, the analogues, desmopressin, oxytocin and salmon calcitonin are already marketed for intranasal administration; for salmon calcitonin, studies about bioavailability have been scanty in the past, but should be re-considered in order to fully explore its clinical benefit.intranasal peptide hormones not yet on the market are insulin, glucagon, growth hormone releasing hormone (ghrh) and ghrp, gh and somatostatin, but the scenario is likely to change in a short period of time. |
2019-11-20 |
2023-08-12 |
Not clear |
Zwirska-Korczala, Ostrowska, Fryczkowsk. Effect of long-term androgen treatment on the function of hypothalamo-hypophysial and -adrenal axes in transsexual agonadal women. Endocrine regulations. vol 30. issue 3. 2019-11-20. PMID:10979047. |
the study was aimed at assessing the influence of prolonged (18-24 months) androgen treatment of 11 agonadal transsexual women on basal concentrations of lh, fsh, testosterone (t), estradiol (e2), progesterone (p) and shbg, on the hypothalamic-hypophysial (gh, prl, acth) and hypothalamic-adrenal (cortisol) response in insulin test and tsh and prl response after trh administration. |
2019-11-20 |
2023-08-12 |
Not clear |
Zwirska-Korczala, Ostrowska, Fryczkowsk. Effect of long-term androgen treatment on the function of hypothalamo-hypophysial and -adrenal axes in transsexual agonadal women. Endocrine regulations. vol 30. issue 3. 2019-11-20. PMID:10979047. |
in most ts women the stimulated secretion of gh, prl, acth and cortisol in insulin test was diminished. |
2019-11-20 |
2023-08-12 |
Not clear |
Ostrowska, Buntner, Zwirska-Korczala, Pardela, Drozd. Assessment of relationship between hypothalamo-pituitary dysfunction and peripheral endocrine function in normotensive and hypertensive obese men. Endocrine regulations. vol 30. issue 4. 2019-11-20. PMID:10979048. |
hyperinsulinaemia in obese men was associated with altered hypothalamo-pituitary function as indicated by impaired gh, prl and cortisol secretion in response to insulin induced hypoglycaemia. |
2019-11-20 |
2023-08-12 |
human |
Ostrowska, Zwirska-Korczala, Buntner, Pardela, Drozd. Effect operative weight reduction on Hypothalamo-Pituitary, -adrenal and -ovarian axes function in obese women with menstrual disturbances. Endocrine regulations. vol 29. issue 4. 2019-11-20. PMID:10993982. |
the aim of the study was to evaluate insulin (ins), pituitary hormones (gh, prl, lh, fsh), sex hormone-binding globulin (shbg) and insulin-like growth factor-i (igf-i) under basal conditions as well as the changes in gh, prl and f levels after insulin-induced hypoglycemia in 21 obese women before and one year after jejunoileostomy as well as in 20 healthy female volunteers with normal body weight (aged 27 to 36 years). |
2019-11-20 |
2023-08-12 |
human |
Boguslawa Baranowska, Malgorzata Radzikowska, Elzbieta Wasilewska-Dziubinska, Artur Plonowski, Krzysztof Roguski, Anna Legowska, Józef Przybylsk. New analogs of somatostatin: inhibiting effectively GH, glucagon and insulin levels. Neuro endocrinology letters. vol 20. issue 3-4. 2019-11-20. PMID:11462119. |
new analogs of somatostatin: inhibiting effectively gh, glucagon and insulin levels. |
2019-11-20 |
2023-08-12 |
rat |
Boguslawa Baranowska, Malgorzata Radzikowska, Elzbieta Wasilewska-Dziubinska, Artur Plonowski, Krzysztof Roguski, Anna Legowska, Józef Przybylsk. New analogs of somatostatin: inhibiting effectively GH, glucagon and insulin levels. Neuro endocrinology letters. vol 20. issue 3-4. 2019-11-20. PMID:11462119. |
the in vivo effects of three new analogs of somatostatin (ass-51, ass-52 and ass-53 analogs) on gh, insulin and glucagon were studied in wky rats. |
2019-11-20 |
2023-08-12 |
rat |
James N. Roemmich, Alan D. Rogo. Hormonal changes during puberty and their relationship to fat distribution. American journal of human biology : the official journal of the Human Biology Council. vol 11. issue 2. 2019-11-20. PMID:11533945. |
cortisol and insulin promote fat deposition while the sex steroids and gh stimulate lipolysis. |
2019-11-20 |
2023-08-12 |
Not clear |
Quan Jiang, Jin Bai, Mulan He, Karen W Y Yuen, Anderson O L Won. Mechanisms Underlying the Synergistic Action of Insulin and Growth Hormone on IGF-I and -II Expression in Grass Carp Hepatocytes. Frontiers in endocrinology. vol 9. 2019-11-20. PMID:29977227. |
in mammals, insulin is known to modify growth hormone (gh)-induced igf-i expression at the hepatic level, which also contributes to the functional crosstalk between energy homeostasis and somatotropic axis. |
2019-11-20 |
2023-08-13 |
Not clear |
Quan Jiang, Jin Bai, Mulan He, Karen W Y Yuen, Anderson O L Won. Mechanisms Underlying the Synergistic Action of Insulin and Growth Hormone on IGF-I and -II Expression in Grass Carp Hepatocytes. Frontiers in endocrinology. vol 9. 2019-11-20. PMID:29977227. |
using a serum-free culture of grass carp hepatoctyes, the functional interaction between gh and insulin on hepatic expression of igf-i and -ii was examined in a fish model. |
2019-11-20 |
2023-08-13 |
Not clear |
b' Francesco Ferra\\xc3\\xb9, Adriana Albani, Alessandro Ciresi, Carla Giordano, Salvatore Cannav\\xc3\\xb. Diabetes Secondary to Acromegaly: Physiopathology, Clinical Features and Effects of Treatment. Frontiers in endocrinology. vol 9. 2019-11-20. PMID:30034367.' |
indeed, chronic gh excess impairs insulin sensitivity, increases gluconeogenesis, reduces the glucose uptake in adipose tissue and muscle and alters pancreatic β cells function. |
2019-11-20 |
2023-08-13 |
Not clear |
Kim Mja Claessen, Alberto M Pereira, Nienke R Biermas. Outcome of complications in acromegaly patients after long-term disease remission. Expert review of endocrinology & metabolism. vol 10. issue 5. 2019-11-20. PMID:30298766. |
during active disease, gh excess is associated with a number of pathological conditions, such as hypertension, hypertrophic cardiomyopathy, sleep apnea, arthropathy, vertebral fractures and insulin resistance. |
2019-11-20 |
2023-08-13 |
Not clear |
Daniel Landau, Yael Sege. Role of IGF-I in Type 2 diabetes: a focus on the mouse model. Expert review of endocrinology & metabolism. vol 3. issue 1. 2019-11-20. PMID:30743784. |
insulin resistance, the key mechanism in type 2 diabetes mellitus (t2dm) is also associated with the deregulation of other glucose homeostasis pathways, such as the growth hormone (gh)-igf-i system. |
2019-11-20 |
2023-08-13 |
mouse |
Rakesh Amin, David B Dunge. Growth hormone hypothesis and development of diabetic nephropathy in Type 1 diabetes. Expert review of endocrinology & metabolism. vol 1. issue 5. 2019-11-20. PMID:30754096. |
in type 1 diabetes, the characteristic pattern of gh hypersecretion and low circulating igf-1 levels results from hepatic gh resistance owing to the lack of portal insulin. |
2019-11-20 |
2023-08-13 |
Not clear |
Rakesh Amin, David B Dunge. Growth hormone hypothesis and development of diabetic nephropathy in Type 1 diabetes. Expert review of endocrinology & metabolism. vol 1. issue 5. 2019-11-20. PMID:30754096. |
clinical data indicate that high gh and low igf-1 levels reduce insulin sensitivity and worsen glycemic control. |
2019-11-20 |
2023-08-13 |
Not clear |
Rakesh Amin, David B Dunge. Growth hormone hypothesis and development of diabetic nephropathy in Type 1 diabetes. Expert review of endocrinology & metabolism. vol 1. issue 5. 2019-11-20. PMID:30754096. |
although such data in humans are limited, preliminary trials show that interventions to increase igf-1 levels and reduce gh hypersecretion improve glycemic control and insulin sensitivity in the short term. |
2019-11-20 |
2023-08-13 |
Not clear |