| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Silvana Duran-Ortiz, Vanessa Noboa, John J Kopchic. Disruption of the GH receptor gene in adult mice and in insulin sensitive tissues. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 38. 2018-08-30. PMID:29198419. |
to elucidate whether a specific tissue is responsible for the beneficial health and longevity phenotype seen in growth hormone (gh) receptor (r) knockout (ghrko) mice, the ghr gene was disrupted specifically in insulin sensitive tissues; namely, liver, adipose, and muscle. |
2018-08-30 |
2023-08-13 |
mouse |
| Jaime Guevara-Aguirre, Alexandra Guevara, Marisol Bahamond. Insulin resistance depends on GH counter-regulation in two syndromes of short stature. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 38. 2018-08-30. PMID:29306561. |
insulin resistance depends on gh counter-regulation in two syndromes of short stature. |
2018-08-30 |
2023-08-13 |
human |
| Jaime Guevara-Aguirre, Alexandra Guevara, Marisol Bahamond. Insulin resistance depends on GH counter-regulation in two syndromes of short stature. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 38. 2018-08-30. PMID:29306561. |
subjects with laron syndrome (ls), who have gh insensitivity (ghi), display obesity, increased body fat, enhanced insulin sensitivity and diminished incidence of diabetes mellitus. |
2018-08-30 |
2023-08-13 |
human |
| Jaime Guevara-Aguirre, Alexandra Guevara, Marisol Bahamond. Insulin resistance depends on GH counter-regulation in two syndromes of short stature. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 38. 2018-08-30. PMID:29306561. |
subjects with a new syndrome (ns), who have normal gh signaling, display intrauterine growth retardation (iugr), normal to slightly elevated body fat content, insulin resistance and early onset type 2 diabetes mellitus (t2dm). |
2018-08-30 |
2023-08-13 |
human |
| Jaime Guevara-Aguirre, Alexandra Guevara, Iván Palacios, Mónica Pérez, Patricio Prócel, Enrique Terá. GH and GHR signaling in human disease. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 38. 2018-08-30. PMID:29395968. |
regarding development of type 2 diabetes, we support the notion that gh, by influencing insulin sensitivity via its counter-regulatory properties on carbohydrate metabolism, is an important contributor for development of this disease. |
2018-08-30 |
2023-08-13 |
human |
| Han Qiu, Jin-Kui Yang, Chen Che. Influence of insulin on growth hormone secretion, level and growth hormone signalling. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 5. 2018-08-29. PMID:29063103. |
glucose and lipid levels in circulation and dietary habits may influence the effect of insulin on gh secretion. |
2018-08-29 |
2023-08-13 |
Not clear |
| Han Qiu, Jin-Kui Yang, Chen Che. Influence of insulin on growth hormone secretion, level and growth hormone signalling. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 5. 2018-08-29. PMID:29063103. |
insulin may also affect ghr sensitivity and the level of insulin-like growth factor 1 (igf-1), thus influence the level of gh. |
2018-08-29 |
2023-08-13 |
Not clear |
| Han Qiu, Jin-Kui Yang, Chen Che. Influence of insulin on growth hormone secretion, level and growth hormone signalling. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 5. 2018-08-29. PMID:29063103. |
these pathways may be shared by insulin, which is the basis for the interaction between insulin and gh, and insulin may attenuate or facilitate the gh signal by influencing molecules in the pathways. |
2018-08-29 |
2023-08-13 |
Not clear |
| Han Qiu, Jin-Kui Yang, Chen Che. Influence of insulin on growth hormone secretion, level and growth hormone signalling. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 5. 2018-08-29. PMID:29063103. |
the tendency of insulin-reduced gh signaling becomes obvious with increased dose and acting time of insulin. |
2018-08-29 |
2023-08-13 |
Not clear |
| Han Qiu, Jin-Kui Yang, Chen Che. Influence of insulin on growth hormone secretion, level and growth hormone signalling. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 5. 2018-08-29. PMID:29063103. |
the details of how gh secretion, level and signaling change in response to time and dose of insulin treatment warrant further studies. |
2018-08-29 |
2023-08-13 |
Not clear |
| Flavio A Cadegiani, Claudio E Kate. Hormonal response to a non-exercise stress test in athletes with overtraining syndrome: results from the Endocrine and metabolic Responses on Overtraining Syndrome (EROS) - EROS-STRESS. Journal of science and medicine in sport. vol 21. issue 7. 2018-08-27. PMID:29157780. |
hence, we aimed to evaluate growth hormone (gh) and prolactin responses to a gold-standard and exercise-independent stimulation test, the insulin tolerance test (itt). |
2018-08-27 |
2023-08-13 |
Not clear |
| Esben T Vestergaard, Niels Jessen, Niels Møller, Jens Otto Lunde Jørgense. Acyl Ghrelin Induces Insulin Resistance Independently of GH, Cortisol, and Free Fatty Acids. Scientific reports. vol 7. 2018-08-02. PMID:28198428. |
acyl ghrelin induces insulin resistance independently of gh, cortisol, and free fatty acids. |
2018-08-02 |
2023-08-13 |
Not clear |
| Esben T Vestergaard, Niels Jessen, Niels Møller, Jens Otto Lunde Jørgense. Acyl Ghrelin Induces Insulin Resistance Independently of GH, Cortisol, and Free Fatty Acids. Scientific reports. vol 7. 2018-08-02. PMID:28198428. |
we investigated the impact of ghrelin and pharmacological antilipolysis (acipimox) on insulin sensitivity and substrate metabolism in 8 adult hypopituitary patients on stable replacement with gh and hydrocortisone using a 2 × 2 factorial design: ghrelin infusion, saline infusion, ghrelin plus short-term acipimox, and acipimox alone. |
2018-08-02 |
2023-08-13 |
Not clear |
| Esben T Vestergaard, Niels Jessen, Niels Møller, Jens Otto Lunde Jørgense. Acyl Ghrelin Induces Insulin Resistance Independently of GH, Cortisol, and Free Fatty Acids. Scientific reports. vol 7. 2018-08-02. PMID:28198428. |
our data demonstrate that ghrelin induces peripheral insulin resistance independently of gh, cortisol, and ffa. |
2018-08-02 |
2023-08-13 |
Not clear |
| Hiroshi Nishioka, Noriaki Fukuhara, Mitsuo Yamaguchi-Okada, Akira Takeshita, Yasuhiro Takeuchi, Shozo Yamad. Pitfalls in early biochemical evaluation after transsphenoidal surgery in patients with acromegaly. Endocrine journal. vol 64. issue 11. 2018-07-27. PMID:28835593. |
for the accurate evaluation within a year after surgery, however, influence of preoperative treatment with ssa, delayed normalization of igf-1, and poor gh suppression due to low insulin resistance must be considered, particularly in women. |
2018-07-27 |
2023-08-13 |
Not clear |
| R J van Hoeij, J Dijkstra, R M Bruckmaier, J J Gross, T J G M Lam, G J Remmelink, B Kemp, A T M van Knegse. Consequences of dietary energy source and energy level on energy balance, lactogenic hormones, and lactation curve characteristics of cows after a short or omitted dry period. Journal of dairy science. vol 100. issue 10. 2018-06-04. PMID:28822552. |
the aim of this study was to evaluate the effect of dietary energy source-glucogenic (g) or lipogenic (l)-and energy level-standard (std) or low-on milk production; energy balance (eb); lactogenic hormones insulin, insulin-like growth factor 1 (igf-1), and growth hormone (gh); and lactation curve characteristics between wk 1 and 44 postpartum in cows after a 0-d or 30-d dp. |
2018-06-04 |
2023-08-13 |
Not clear |
| Casey J A Smith-Anttila, Sophie Bensing, Mohammad Alimohammadi, Frida Dalin, Mikael Oscarson, Ming-Dong Zhang, Jaakko Perheentupa, Eystein S Husebye, Jan Gustafsson, Peyman Björklund, Anette Fransson, Gunnel Nordmark, Lars Rönnblom, Antonella Meloni, Rodney J Scott, Tomas Hökfelt, Patricia A Crock, Olle Kämp. Identification of endothelin-converting enzyme-2 as an autoantigen in autoimmune polyendocrine syndrome type 1. Autoimmunity. vol 50. issue 4. 2018-05-11. PMID:28557628. |
in the pancreas ece-2 was co-expressed with insulin or somatostatin, but not glucagon and was widely expressed in gh producing cells in the guinea pig pituitary. |
2018-05-11 |
2023-08-13 |
Not clear |
| Manouk van der Steen, Anita C S Hokken-Koeleg. Growth and Metabolism in Children Born Small for Gestational Age. Endocrinology and metabolism clinics of North America. vol 45. issue 2. 2018-05-04. PMID:27241965. |
gh-induced reduction in insulin sensitivity is reversible after stopping gh. |
2018-05-04 |
2023-08-13 |
human |
| Fernando L-López, André Sarmento-Cabral, Vicente Herrero-Aguayo, Manuel D Gahete, Justo P Castaño, Raúl M Luqu. Obesity and metabolic dysfunction severely influence prostate cell function: role of insulin and IGF1. Journal of cellular and molecular medicine. vol 21. issue 9. 2018-04-30. PMID:28244645. |
the endocrine-metabolic regulatory axis comprising growth hormone (gh), insulin and igf1, which is drastically altered under extreme metabolic conditions such as obesity, also plays relevant roles in the development, modulation and homeostasis of the pg. |
2018-04-30 |
2023-08-13 |
mouse |
| Fernando L-López, André Sarmento-Cabral, Vicente Herrero-Aguayo, Manuel D Gahete, Justo P Castaño, Raúl M Luqu. Obesity and metabolic dysfunction severely influence prostate cell function: role of insulin and IGF1. Journal of cellular and molecular medicine. vol 21. issue 9. 2018-04-30. PMID:28244645. |
altogether, these results uncover a fine, germane crosstalk between the endocrine-metabolic status and the development and homeostasis of the pg, wherein key components of the gh, insulin and igf1 axes could play a relevant pathophysiological role. |
2018-04-30 |
2023-08-13 |
mouse |