| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Minoru Narita, Takuya Yoshida, Mayumi Nakajima, Michiko Narita, Mayumi Miyatake, Tomoe Takagi, Yoshinori Yajima, Tsutomu Suzuk. Direct evidence for spinal cord microglia in the development of a neuropathic pain-like state in mice. Journal of neurochemistry. vol 97. issue 5. 2006-07-21. PMID:16606373. |
at 7 days after sciatic nerve ligation, the immunoreactivities (irs) of the specific astrocyte marker glial fibrillary acidic protein (gfap) and the specific microglial marker ox-42, but not the specific oligodendrocyte marker o4, were increased on the ipsilateral side of the spinal cord dorsal horn in nerve-ligated mice compared with that on the contralateral side. |
2006-07-21 |
2023-08-12 |
mouse |
| Minoru Narita, Takuya Yoshida, Mayumi Nakajima, Michiko Narita, Mayumi Miyatake, Tomoe Takagi, Yoshinori Yajima, Tsutomu Suzuk. Direct evidence for spinal cord microglia in the development of a neuropathic pain-like state in mice. Journal of neurochemistry. vol 97. issue 5. 2006-07-21. PMID:16606373. |
furthermore, 5-bromo-2'-deoxyuridine (brdu)-positive cells on the ipsilateral dorsal horn of the spinal cord were significantly increased at 7 days after nerve ligation and were highly co-localized with another microglia marker, ionized calcium-binding adaptor molecule 1 (iba1), but neither with gfap nor a specific neural nuclei marker, neun, in the spinal dorsal horn of nerve-ligated mice. |
2006-07-21 |
2023-08-12 |
mouse |
| Young Seob Gwak, Claire E Hulsebosc. Upregulation of Group I metabotropic glutamate receptors in neurons and astrocytes in the dorsal horn following spinal cord injury. Experimental neurology. vol 195. issue 1. 2005-10-27. PMID:16004983. |
expression was determined by confocal analyses of immunocytochemical reaction product of neurons (neun positive) and astrocytes (gfap positive) in the dorsal horn on both sides of the l4 segment. |
2005-10-27 |
2023-08-12 |
rat |
| S Tenschert, A Reinert, U Hoheisel, S Mens. Effects of a chronic myositis on structural and functional features of spinal astrocytes in the rat. Neuroscience letters. vol 361. issue 1-3. 2004-08-30. PMID:15135927. |
after 12 days, the immunoreactivity (ir) for glial fibrillary acidic protein (gfap), morphometric parameters, and fibroblast growth factor-2 (fgf-2) expression of astrocytes were quantitatively evaluated in the dorsal horn of the spinal segment l4. |
2004-08-30 |
2023-08-12 |
rat |
| Elena N Kozlov. Differentiation and migration of astrocytes in the spinal cord following dorsal root injury in the adult rat. The European journal of neuroscience. vol 17. issue 4. 2004-04-21. PMID:12603268. |
nestin-positive cells coexpressed the calcium-binding protein mts1, a marker for white matter astrocytes, in the dorsal funiculus, and were positive for glial fibrillary acidic protein (gfap), but negative for mts1 in the dorsal horn. |
2004-04-21 |
2023-08-12 |
rat |
| Minoru Narita, Masami Suzuki, Michiko Narita, Yoshinori Yajima, Ryusuke Suzuki, Seiji Shioda, Tsutomu Suzuk. Neuronal protein kinase C gamma-dependent proliferation and hypertrophy of spinal cord astrocytes following repeated in vivo administration of morphine. The European journal of neuroscience. vol 19. issue 2. 2004-03-18. PMID:14725643. |
here we found a dramatic increase in reactive astrocytes in the dorsal horn of the spinal cord following repeated treatment with morphine, as characterized by the increase and morphological changes in glial fibrillary acidic protein (gfap)-positive cells. |
2004-03-18 |
2023-08-12 |
mouse |
| Weiya Ma, Remi Quirio. Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus. Pain. vol 99. issue 1-2. 2002-12-06. PMID:12237195. |
at 3 weeks post-lesion, psnl markedly increased glia fibrillary acidic protein (gfap) immunoreactive (ir) astrocytes in both the l4-5 spinal dorsal horn and the gracile nucleus. |
2002-12-06 |
2023-08-12 |
rat |
| R Griffith, J Suti. Reactive astrocyte formation in vivo is regulated by noradrenergic axons. The Journal of comparative neurology. vol 371. issue 3. 1997-01-02. PMID:8842893. |
gfap density was increased about 55% in the injured ne-hyperinnervated mov and was decreased about 35% in the injured ne-depleted dorsal horn. |
1997-01-02 |
2023-08-12 |
Not clear |
| G Bodega, I Suárez, E Arilla, M Rubio, B Fernánde. Heterogeneous astroglial response in the rat spinal cord to long-term portacaval shunt: an immunohistochemical study. Glia. vol 4. issue 4. 1991-12-23. PMID:1834560. |
in general, astrocytes show a loss of gfap immunoreactivity, as well as shrinking and pyknosis in their nuclei; however, while gfap reactivity was unchanged in the periependymal region, it was strongly increased in the dorsolateral region of the spinal cord (lateral spinal nucleus, dorsal root entry zone, and the most dorsal region of the dorsal horn). |
1991-12-23 |
2023-08-11 |
rat |
| F Hajós, B Csillik, E Knyihár-Csilli. Alterations in glial fibrillary acidic protein immunoreactivity in the upper dorsal horn of the rat spinal cord in the course of transganglionic degenerative atrophy and regenerative proliferation. Neuroscience letters. vol 117. issue 1-2. 1991-04-01. PMID:2290624. |
transection of a peripheral nerve induces marked increase in the glial fibrillary acidic protein (gfap) immunoreactivity in the ipsilateral, segmentally related upper dorsal horn. |
1991-04-01 |
2023-08-11 |
rat |
| F Hajós, B Csillik, E Knyihár-Csilli. Alterations in glial fibrillary acidic protein immunoreactivity in the upper dorsal horn of the rat spinal cord in the course of transganglionic degenerative atrophy and regenerative proliferation. Neuroscience letters. vol 117. issue 1-2. 1991-04-01. PMID:2290624. |
if the peripheral nerve succeeds in regenerating, gfap immunoreactivity in the upper dorsal horn returns to normal. |
1991-04-01 |
2023-08-11 |
rat |
| M Murray, S D Wang, M E Goldberger, P Levit. Modification of astrocytes in the spinal cord following dorsal root or peripheral nerve lesions. Experimental neurology. vol 110. issue 3. 1991-01-11. PMID:2174376. |
multiple dorsal root section elicited a rapid increase in gfap immunoreactivity of astrocytes unilaterally within the spinal cord along the pathway of the degenerating dorsal root axons in the dorsal and ventral horns and this gliosis persisted in the dorsal horn beyond the time at which active phagocytosis of degenerative debris occurred. |
1991-01-11 |
2023-08-11 |
rat |
| M Murray, S D Wang, M E Goldberger, P Levit. Modification of astrocytes in the spinal cord following dorsal root or peripheral nerve lesions. Experimental neurology. vol 110. issue 3. 1991-01-11. PMID:2174376. |
transganglionic changes in gfap staining in the dorsal horn occur by 3 days post-operatively, which is much earlier than the time of dorsal root ganglion neuron death caused by the sciatic nerve lesion. |
1991-01-11 |
2023-08-11 |
rat |