| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Honghua Niu, Wenchao Song, Dongyang Pei, Chen Ma, Fudong Liu, Yan Li, Shuaiwei Ha. Depleted histone deacetylase 3 or restored microRNA-19b-1-5p facilitates recovery of spinal cord injury via inactivating JAK2/STAT3 signaling pathway. Genomics. 2021-12-31. PMID:34971719. |
also, by measuring gfap expression and migration of spinal cord astrocytes, the effects of hdac3 and mir-19b-1-5p in sci were identified in vitro. |
2021-12-31 |
2023-08-13 |
rat |
| Honghua Niu, Wenchao Song, Dongyang Pei, Chen Ma, Fudong Liu, Yan Li, Shuaiwei Ha. Depleted histone deacetylase 3 or restored microRNA-19b-1-5p facilitates recovery of spinal cord injury via inactivating JAK2/STAT3 signaling pathway. Genomics. 2021-12-31. PMID:34971719. |
restoration of mir-19b-1-5p or depletion of hdac3 attenuated motor function, inflammation, pathological damage and apoptosis, and reduced gfap expression in the spinal cord tissue of sci rats. |
2021-12-31 |
2023-08-13 |
rat |
| Xin-Hong Wang, Xiao-Chen Tang, Xia Li, Jian-Zhong Qin, Wen-Tao Zhong, Peng Wu, Feng Zhang, Yi-Xin Shen, Ting-Ting Da. Implantation of nanofibrous silk scaffolds seeded with bone marrow stromal cells promotes spinal cord regeneration (6686 words). Artificial cells, nanomedicine, and biotechnology. vol 49. issue 1. 2021-12-10. PMID:34882059. |
recovery of the damaged spinal cord was significantly improved after 2 months, compared with a non-nanofibrous scaffold, in combination with decreased glial fibrillary acidic protein (gfap) expression and improved axonal regeneration at the site of injury. |
2021-12-10 |
2023-08-13 |
Not clear |
| Sanjay Kumar, Manjula Vinaya. Quercetin Ameliorates CFA-Induced Chronic Inflammatory Hyperalgesia via Modulation of ROS-Mediated ERK1/2 Signaling and Inhibition of Spinal Glial Activation In Vivo. Neuromolecular medicine. vol 22. issue 4. 2021-11-23. PMID:32813234. |
up-regulation of iba1 and gfap indicates glial activation in spinal cord. |
2021-11-23 |
2023-08-13 |
Not clear |
| Bailey Balouch, Jessica L Funnell, Alexis M Ziemba, Devan L Puhl, Kathy Lin, Manoj K Gottipati, Ryan J Gilber. Conventional immunomarkers stain a fraction of astrocytes in vitro: A comparison of rat cortical and spinal cord astrocytes in naïve and stimulated cultures. Journal of neuroscience research. vol 99. issue 3. 2021-11-23. PMID:33295039. |
furthermore, significantly more cortical than spinal cord astrocytes stained for gfap, glast, and aldh1l1 in naïve cultures, whereas significantly more spinal cord than cortical astrocytes stained for glast and gs in tgf-β1-treated cultures. |
2021-11-23 |
2023-08-13 |
rat |
| Yeyang Wang, Man Xiong, Mingsen Wang, Hongdong Chen, Wenjun Li, Xiaozhong Zho. Quercetin promotes locomotor function recovery and axonal regeneration through induction of autophagy after spinal cord injury. Clinical and experimental pharmacology & physiology. vol 48. issue 12. 2021-11-18. PMID:34407225. |
in addition, que inhibited gfap expression, increased both neun and nf-200 expression and facilitated the spinal cord energy metabolism. |
2021-11-18 |
2023-08-13 |
rat |
| Xiao Li, Yuantao Gao, Feng Tian, Ruochen Du, Yitong Yuan, Pengfei Li, Fang Liu, Chunfang Wan. miR-31 promotes neural stem cell proliferation and restores motor function after spinal cord injury. Experimental biology and medicine (Maywood, N.J.). vol 246. issue 11. 2021-11-05. PMID:33715531. |
after the injection of a mir-31 agomir in spinal cord injury mice, the expression of nestin and gfap increased, while gfap expression decreased. |
2021-11-05 |
2023-08-13 |
mouse |
| Samira Ahmadvand Koohsari, Abdorrahim Absalan, Davood Azad. Human umbilical cord mesenchymal stem cell-derived extracellular vesicles attenuate experimental autoimmune encephalomyelitis via regulating pro and anti-inflammatory cytokines. Scientific reports. vol 11. issue 1. 2021-11-05. PMID:34079033. |
cytokine expression of pro-/anti-inflammatory cytokine by real-time pcr, leukocyte infiltration by hematoxylin and eosin (h&e) staining, and the percent of glial fibrillary acidic protein (gfap) and myelin basic protein (mbp) positive cells by immunohistochemistry were assessed in the spinal cord. |
2021-11-05 |
2023-08-13 |
mouse |
| Samira Ahmadvand Koohsari, Abdorrahim Absalan, Davood Azad. Human umbilical cord mesenchymal stem cell-derived extracellular vesicles attenuate experimental autoimmune encephalomyelitis via regulating pro and anti-inflammatory cytokines. Scientific reports. vol 11. issue 1. 2021-11-05. PMID:34079033. |
there was no significant difference in the percent of gfap and mbp positive cells in the spinal cord of experimental groups. |
2021-11-05 |
2023-08-13 |
mouse |
| Chang-Lung Lee, Ato O Wright, Jessica W Lee, Jeremy Brownstein, Stephanie Hasapis, Sloane Satow, Lorraine Da Silva Campos, Nerissa Williams, Yan Ma, Lixia Luo, Timothy Johnson, Andrea R Daniel, William T Harrison, Mark Oldham, David G Kirsc. Sensitization of Endothelial Cells to Ionizing Radiation Exacerbates Delayed Radiation Myelopathy in Mice. Radiation research. vol 197. issue 3. 2021-11-05. PMID:34724704. |
in addition, 8 weeks after 28.4 gy the irradiated spinal cord from tie2cre; p53fl/- mice showed a significantly higher fractional area positive for the neurological injury marker glial fibrillary acidic protein (gfap) compared with the irradiated spinal cord from tie2cre; p53fl/+ mice. |
2021-11-05 |
2023-08-13 |
mouse |
| Mawj Mandwie, Jordan A Piper, Catherine A Gorrie, Kevin A Keay, Giuseppe Musumeci, Ghaith Al-Badri, Alessandro Castorin. Rapid GFAP and Iba1 expression changes in the female rat brain following spinal cord injury. Neural regeneration research. vol 17. issue 2. 2021-10-22. PMID:34269213. |
rapid gfap and iba1 expression changes in the female rat brain following spinal cord injury. |
2021-10-22 |
2023-08-13 |
rat |
| Peisong Zhang, Hanyu Sun, Zhengang J. Downregulating lncRNA PVT1 Relieves Astrocyte Overactivation Induced Neuropathic Pain Through Targeting miR-186-5p/CXCL13/CXCR5 Axis. Neurochemical research. vol 46. issue 6. 2021-10-12. PMID:33742328. |
western blot was conducted to detect the expression of chemokine ligand 13 (cxcl13), chemokine receptor 5 (cxcr5), cyclooxygenase-2 (cox2), inducible nitric oxide synthase (inos) and glial fibrillary acidic protein (gfap) in spinal cord injury lesions. |
2021-10-12 |
2023-08-13 |
rat |
| Jonathan Paulo Agnes, Vitória Wibbelt Dos Santos, Raquel Nascimento das Neves, Rosângela Mayer Gonçalves, Marina Delgobo, Carolina Saibro Girardi, Débora Denardin Lückemeyer, Marcella de Amorim Ferreira, Sérgio José Macedo-Júnior, Samantha Cristiane Lopes, Fernando Spiller, Daniel Pens Gelain, José Cláudio Fonseca Moreira, Rui Daniel Prediger, Juliano Ferreira, Alfeu Zanotto-Filh. Antioxidants Improve Oxaliplatin-Induced Peripheral Neuropathy in Tumor-Bearing Mice Model: Role of Spinal Cord Oxidative Stress and Inflammation. The journal of pain. vol 22. issue 8. 2021-10-06. PMID:33774154. |
oxa increased reactive oxygen species (ros) production and lipoperoxidation, and augmented the content of pro-inflammatory cytokines (il-1β and tnf-α) and expression of the astrocytic marker gfap mrna in the spinal cord. |
2021-10-06 |
2023-08-13 |
mouse |
| Amira Mohamed Abdelhamid, Shireen Sami Mahmoud, Aziza E Abdelrahman, Nelly Mohamed Said, Mostafa Toam, Walaa Samy, Marwa AbdEl-Moniem Ame. Protective effect of cerium oxide nanoparticles on cisplatin and oxaliplatin primary toxicities in male albino rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 12. 2021-09-24. PMID:32710137. |
the right sciatic nerves and the lumbar spinal cord of rats from control, conps, and oxaliplatin groups were used for immunohistochemical evaluations of nitrotyrosine, myelin basic protein (mbp), and glial fibrillary acidic protein (gfap). |
2021-09-24 |
2023-08-13 |
rat |
| Amira Mohamed Abdelhamid, Shireen Sami Mahmoud, Aziza E Abdelrahman, Nelly Mohamed Said, Mostafa Toam, Walaa Samy, Marwa AbdEl-Moniem Ame. Protective effect of cerium oxide nanoparticles on cisplatin and oxaliplatin primary toxicities in male albino rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 12. 2021-09-24. PMID:32710137. |
in the lumbar spinal cord, gfap immunoreactivity was significantly increased. |
2021-09-24 |
2023-08-13 |
rat |
| Wouter J C van Ballegoij, Stephanie I W van de Stadt, Irene C Huffnagel, Stephan Kemp, Eline A J Willemse, Charlotte E Teunissen, Marc Engele. Plasma NfL and GFAP as biomarkers of spinal cord degeneration in adrenoleukodystrophy. Annals of clinical and translational neurology. vol 7. issue 11. 2021-09-24. PMID:33047897. |
plasma nfl and gfap as biomarkers of spinal cord degeneration in adrenoleukodystrophy. |
2021-09-24 |
2023-08-13 |
Not clear |
| Wouter J C van Ballegoij, Stephanie I W van de Stadt, Irene C Huffnagel, Stephan Kemp, Eline A J Willemse, Charlotte E Teunissen, Marc Engele. Plasma NfL and GFAP as biomarkers of spinal cord degeneration in adrenoleukodystrophy. Annals of clinical and translational neurology. vol 7. issue 11. 2021-09-24. PMID:33047897. |
to explore the potential of neurofilament light (nfl) and glial fibrillary acidic protein (gfap) as biomarkers of spinal cord degeneration in adrenoleukodystrophy, as objective treatment-outcome parameters are needed. |
2021-09-24 |
2023-08-13 |
Not clear |
| Iris Leister, Barbara Altendorfer, Doris Maier, Orpheus Mach, Christof Wutte, Andreas Grillhösl, Angel Arevalo Martin, Daniel Garcia-Ovejero, Ludwig Aigner, Lukas Grassne. Serum levels of GFAP and NfL are related to the neurological impairment and spinal edema after traumatic spinal cord injury. Journal of neurotrauma. 2021-09-20. PMID:34541888. |
serum levels of gfap and nfl are related to the neurological impairment and spinal edema after traumatic spinal cord injury. |
2021-09-20 |
2023-08-13 |
Not clear |
| Jana Fedorova, Erika Kellerova, Katarina Bimbova, Jaroslav Pave. The Histopathology of Severe Graded Compression in Lower Thoracic Spinal Cord Segment of Rat, Evaluated at Late Post-injury Phase. Cellular and molecular neurobiology. 2021-09-18. PMID:34410553. |
at the end of the survival period, the degradation of gray and white matter associated with the formation of cystic cavities, and quantitative changes of glial structural proteins, such as gfap, and integral components of axonal architecture, such as neurofilaments and myelin basic protein, were evaluated in the lesioned area of the spinal cord. |
2021-09-18 |
2023-08-13 |
rat |
| Xiao Xiao, Weiwei Li, Dingchao Rong, Zhenchao Xu, Zhen Zhang, Hongru Ye, Liqiong Xie, Yunqi Wu, Yilu Zhang, Xiyang Wan. Human umbilical cord mesenchymal stem cells-derived extracellular vesicles facilitate the repair of spinal cord injury via the miR-29b-3p/PTEN/Akt/mTOR axis. Cell death discovery. vol 7. issue 1. 2021-08-31. PMID:34381025. |
levels of neun, gfap, and nf200 in spinal cord tissues were detected and cell apoptosis was measured. |
2021-08-31 |
2023-08-13 |
human |