| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gehua Wen, Xiaoni Zhan, Xiaoming Xu, Xi Xia, Shukun Jiang, Xinghua Ren, Weishu Ren, Haoyang Lou, Lei Lu, Anca Hermenean, Jun Yao, Lina Gao, Baoman Li, Yan Lu, Xu W. Ketamine Improves the Glymphatic Pathway by Reducing the Pyroptosis of Hippocampal Astrocytes in the Chronic Unpredictable Mild Stress Model. Molecular neurobiology. 2023-10-15. PMID:37840071. |
meanwhile, ketamine reduced the level of hippocampus nlrp3 and the expression of its downstream molecules in chronic unpredictable mild stress (cums) mice model by western blot and reduced the colocalization of gfap and gsdmd by nearly 25% via immunofluorescent staining. |
2023-10-15 |
2023-11-08 |
mouse |
| Εvgenia Dandi, Paschalis Theotokis, Maria Christina Petri, Vaia Sideropoulou, Evangelia Spandou, Despina A Tat. Environmental enrichment initiated in adolescence restores the reduced expression of synaptophysin and GFAP in the hippocampus of chronically stressed rats in a sex-specific manner. Developmental psychobiology. vol 65. issue 7. 2023-10-05. PMID:37796476. |
environmental enrichment initiated in adolescence restores the reduced expression of synaptophysin and gfap in the hippocampus of chronically stressed rats in a sex-specific manner. |
2023-10-05 |
2023-10-07 |
rat |
| Εvgenia Dandi, Paschalis Theotokis, Maria Christina Petri, Vaia Sideropoulou, Evangelia Spandou, Despina A Tat. Environmental enrichment initiated in adolescence restores the reduced expression of synaptophysin and GFAP in the hippocampus of chronically stressed rats in a sex-specific manner. Developmental psychobiology. vol 65. issue 7. 2023-10-05. PMID:37796476. |
to this end, we studied possible alterations in hippocampal glial fibrillary acidic protein (gfap) and synaptophysin (syn) in cus rats previously housed in ee. |
2023-10-05 |
2023-10-07 |
rat |
| Εvgenia Dandi, Paschalis Theotokis, Maria Christina Petri, Vaia Sideropoulou, Evangelia Spandou, Despina A Tat. Environmental enrichment initiated in adolescence restores the reduced expression of synaptophysin and GFAP in the hippocampus of chronically stressed rats in a sex-specific manner. Developmental psychobiology. vol 65. issue 7. 2023-10-05. PMID:37796476. |
cus reduced the expression of syn in all hippocampal areas, whereas lower gfap expression was evident only in ca1 and ca3. |
2023-10-05 |
2023-10-07 |
rat |
| Steffi De Meyer, Elena R Blujdea, Jolien Schaeverbeke, Mariska Reinartz, Emma S Luckett, Katarzyna Adamczuk, Koen Van Laere, Patrick Dupont, Charlotte E Teunissen, Rik Vandenberghe, Koen Poese. Longitudinal associations of serum biomarkers with early cognitive, amyloid and grey matter changes. Brain : a journal of neurology. 2023-10-03. PMID:37787146. |
whole-brain voxelwise analyses revealed that low aβ1-42/aβ1-40 predicted aβ accumulation within the precuneus and frontal regions, high gfap and nfl predicted grey matter loss within hippocampal regions and low aβ1-42/aβ1-40 predicted grey matter loss in lateral temporal regions. |
2023-10-03 |
2023-10-07 |
human |
| Guoquan Zhang, Qinghan Ren, Ying Lin, Dezheng Zhou, Li Huang, Wen Li, Hong Chang, Guowei Huang, Guowei Huang, Zhenshu Li, Jing Ya. Parental folic acid deficiency delays neurobehavioral development in rat offspring by inhibiting the differentiation of neural stem cells into neurons. The Journal of nutritional biochemistry. 2023-10-03. PMID:37788724. |
for in vivo study, neurobehavioral indexes, and neuron-specific nuclear protein (neun) and glial fibrillary acidic protein (gfap) expression in the brain hippocampus and cerebral cortex of offspring were measured at different time points. |
2023-10-03 |
2023-10-07 |
rat |
| Courtney Cross, Maya Davies, Emma Bateman, Elise Crame, Paul Joyce, Anthony Wignall, Amin Ariaee, Marc Gladman, Hannah Wardill, Joanne M Bowe. Fibre-rich diet attenuates chemotherapy-related neuroinflammation in mice. Brain, behavior, and immunity. 2023-09-27. PMID:37757978. |
in the context of 5-fu, the diet reduced gfap expression in the ca1 region of the hippocampus (p < 0.0001) as well as the midbrain (p = 0.0216). |
2023-09-27 |
2023-10-07 |
mouse |
| Matthew I Hiskens, Katy M Li, Anthony G Schneiders, Andrew S Fennin. Repetitive mild traumatic brain injury-induced neurodegeneration and inflammation is attenuated by acetyl-L-carnitine in a preclinical model. Frontiers in pharmacology. vol 14. 2023-09-25. PMID:37745053. |
rt-pcr analysis of the cortex and hippocampus was undertaken for mapt, gfap, aif1, gria, ccl11, tdp43, and tnf genes. |
2023-09-25 |
2023-10-07 |
mouse |
| Ayae Nomura, Kazuhiro Kurokawa, Kohei Takahashi, Kazuya Miyagawa, Atsumi Mochida-Saito, Hiroshi Takeda, Minoru Tsuj. Possible involvement of inflammasomes on the post-stroke cognitive impairment in a mouse model of embolic cerebral infarct. Physiology & behavior. 2023-09-14. PMID:37709001. |
in addition, the expression levels of ionized calcium-binding adapter protein 1 (iba1), glial fibrillary acidic protein (gfap), apoptosis-associated speck-like protein containing a caspase recruitment domain / target of methylation-induced silencing 1 (asc/tms1), caspase-1, il-1β, il-18 and tumor necrosis factor-α (tnf-α) were significantly increased in the dorsal hippocampus of eci mice. |
2023-09-14 |
2023-10-07 |
mouse |
| Wang Kun, Zhou Jie, Cui Shuai, W U Xin, Zhu Guoqi, W U Shengbing, Zhou Meiq. Electroacupuncture ameliorates cardiac dysfunction in myocardial ischemia model rats: a potential role of the hypothalamic-pituitary-adrenal axis. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. vol 43. issue 5. 2023-09-08. PMID:37679982. |
to verify the hypothesis that electroacupuncture inhibits the hyperactivity of the hypothalamic-pituitary-adrenal (hpa) axis regulating the expression of glial fibrillary acidic protein (gfap) in the hippocampus of acute myocardial ischemia (ami) rats. |
2023-09-08 |
2023-10-07 |
rat |
| Yunting Wang, Xueling Wu, Wujiang Ren, Yanxia Liu, Xueling Dai, Shuo Wang, Qing Huo, Yaxuan Su. Protective effects of fisetin in an Aβ1-42-induced rat model of Alzheimer's disease. Folia neuropathologica. vol 61. issue 2. 2023-08-17. PMID:37587894. |
in addition, hippocampal tissue obtained from fisetin-treated rats revealed a reversal of ab1-42-induced effects on apoptotic pathway protein (caspase-3) expression and inflammatory response of glial fibrillary acidic protein (gfap). |
2023-08-17 |
2023-09-07 |
rat |
| Stephen Lippi, Rachel Barkey, Mya Rodrigue. The cognitive and noncognitive behavioral effects of a high-fat diet in the rTg4510 tau mouse model. Physiology & behavior. 2023-08-05. PMID:37543107. |
in the brain, tau mice had greater levels of glial fibrillary acidic protein (gfap) (p < 0.05) and significantly less hippocampal cell density than wt mice (p < 0.001). |
2023-08-05 |
2023-08-14 |
mouse |
| Tenna Bering, Camilla Gadgaard, Henrik Vorum, Bent Honoré, Martin Fredensborg Rat. Diurnal proteome profile of the mouse cerebral cortex: Conditional deletion of the Bmal1 circadian clock gene elevates astrocyte protein levels and cell abundance in the neocortex and hippocampus. Glia. 2023-07-20. PMID:37470358. |
the proteome of the bmal1 cko cerebral cortex was dominated by upregulated proteins expressed in astrocytes, including gfap (4-fold) and fabp7 (>20-fold), in both the neocortex and hippocampus. |
2023-07-20 |
2023-08-14 |
mouse |
| Xiaoying Gao, Zhipeng You, Cong Huang, Zhixiong Liu, Zixiao Tan, Jiran Li, Yang Liu, Xingan Liu, Fan Wei, Zhijie Fan, Sihua Qi, Jiahang Su. NCBP1 Improves Cognitive Function in Mice by Reducing Oxidative Stress, Neuronal Loss, and Glial Activation After Status Epilepticus. Molecular neurobiology. 2023-07-20. PMID:37474884. |
additionally, overexpressed ncbp1 increased the expression of neun and reduced the expression of gfap and iba-1 in the hippocampus of the mice. |
2023-07-20 |
2023-08-14 |
mouse |
| Lisandra Eda Fusinato Zin, Adriana Fernanda K Vizuete, Etiane Micheli Meyer Callai, Luciana Santa Catarina, Fernanda Fróes, Ana Paula Moreira, Charlanne de Oliveira Marques, Miriara B Leal, Deise Ponzoni, Edela Puricelli, Iraci Lucena da Silva Torres, Carlos-Alberto Gonçalves, Alexandre Silva Queved. Astroglial Alterations in the Hippocampus of Rats Submitted to a Single Trans-Cranial Direct Current Stimulation Trial. Neurochemical research. 2023-07-18. PMID:37464227. |
considering the importance of hippocampal glutamatergic neurotransmission in nociceptive pathways, we decided to investigate short-term changes in the hippocampal astrocytes of rats subjected to tdcs, evaluating specific cellular markers (gfap and s100b), as well as markers of astroglial activity; glutamate uptake, glutamine synthesis by glutamine synthetase (gs) and glutathione content. |
2023-07-18 |
2023-08-14 |
rat |
| Rita Chaaya, Joel R Steele, Brian G Oliver, Hui Chen, Rita Machaalan. Effects of e-vapour and high-fat diet on the immunohistochemical staining of nicotinic acetylcholine receptors, apoptosis, microglia and astrocytes in the adult male mouse hippocampus. Journal of chemical neuroanatomy. 2023-06-21. PMID:37343645. |
this study, using a mouse model, investigated the effects of exposure to e-vapour (± nicotine) and hfd (43% fat) consumption, on the expression of nicotinic acetylcholine receptor (nachr) subunits α3, α4, α7 and β2, apoptosis markers caspase-3 and tunel, microglial marker iba-1, and astrocyte marker gfap, in hippocampal subregions of dentate gyrus (dg) and cornu ammonis (ca) 1-3. |
2023-06-21 |
2023-08-14 |
mouse |
| Farimah Beheshti, Mahmoud Hosseini, Hossein Bakhtiari-Dovvombaygi, Hossein Salmani, Somaieh Ahmadabady, Narges Marefati, Yousef Baghchegh. Rosiglitazone attenuates amyloid beta and glial fibrillary acidic protein in the hippocampus and neuroinflammation associated learning and memory impairments in rats. Behavioural brain research. 2023-06-21. PMID:37343837. |
the aim of the current study was to investigate the beneficial effects of rosiglitazone (rosi) on amyloid beta(aβ) and glial fibrillary acidic (gfap) in the hippocampus and neuroinflammation-associated learning and memory impairments in rats. |
2023-06-21 |
2023-08-14 |
rat |
| Peijun Liu, Pan Zhou, Xinyue Zhang, Dong Zhao, Hao Chen, Ke H. Pterostilbene mediates glial and immune responses to alleviate chronic intermittent hypoxia-induced oxidative stress in nerve cells. PloS one. vol 18. issue 6. 2023-06-02. PMID:37267263. |
pte increased the number of neuronal nissl bodies in the hippocampus of cih mice, upregulated the protein levels of bcl-2, occludin, and zo-1 as well as the mrna and protein levels of camp-response element binding protein (creb) and p-bdnf, and reduced the number of neuronal apoptotic cells, bax protein levels, iba-1, and gfap levels. |
2023-06-02 |
2023-08-14 |
mouse |
| Fang Chen, Ning Bai, Fang Yue, Yabo Hao, Hui Wang, Yun He, Kai L. Effects of Oral β-caryophyllene (BCP) Treatment on Perioperative Neurocognitive Disorders: Attenuation of Neuroinflammation Associated with Microglial Activation and Reinforcement of Autophagy Activity in Aged Mice. Brain research. 2023-05-27. PMID:37244603. |
the extent of hippocampal inflammation was examined by measuring the microglial marker iba-1 protein levels, iba-1 and gfap immunoactivity, as well as il-1β and il-6 concentrations. |
2023-05-27 |
2023-08-14 |
mouse |
| Carolina Muniz Partida, Eric Walter. A novel immunohistochemical protocol for paraffin embedded tissue sections using free-floating techniques. Frontiers in neuroanatomy. vol 17. 2023-05-26. PMID:37235185. |
pffp localized gfap, olfactory marker protein, tyrosine hydroxylase, and nestin expression in mouse hippocampal, olfactory bulb, striatum, and cortical tissue. |
2023-05-26 |
2023-08-14 |
mouse |