| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Beauquis, F Saravia, J Coulaud, P Roig, M Dardenne, F Homo-Delarche, Alejandro De Nicol. Prominently decreased hippocampal neurogenesis in a spontaneous model of type 1 diabetes, the nonobese diabetic mouse. Experimental neurology. vol 210. issue 2. 2008-06-20. PMID:18190910. |
the number of proliferative brdu-positive cells in the dg was, regardless of age, constantly and significantly lower in nod than in control strains, showing the presence of hippocampal alterations far before clinical diabetes onset in nod mice. |
2008-06-20 |
2023-08-12 |
mouse |
| J Beauquis, F Saravia, J Coulaud, P Roig, M Dardenne, F Homo-Delarche, Alejandro De Nicol. Prominently decreased hippocampal neurogenesis in a spontaneous model of type 1 diabetes, the nonobese diabetic mouse. Experimental neurology. vol 210. issue 2. 2008-06-20. PMID:18190910. |
notably, nod hippocampal dg cell proliferation defect takes place during the prediabetic stage. |
2008-06-20 |
2023-08-12 |
mouse |
| Yukiko Ichihashi, Naonori Saito, Yoko Arakawa, Chika Kurata, Mitsuo Iinuma, Yasuo Tamura, Fumihiko Iwaku, Kin-Ya Kub. The bite-raised condition in aged SAMP8 mice reduces the expression of glucocorticoid receptors in the dorsal and ventral hippocampus. Okajimas folia anatomica Japonica. vol 84. issue 4. 2008-06-20. PMID:18464530. |
in the bite-raised condition, the number of gr-immunoreactive cells was significantly decreased in both the dorsal and ventral ca1 and dentate gyrus (dg) subfields of the hippocampus compared to control mice, as revealed by immunohistochemical analysis. |
2008-06-20 |
2023-08-12 |
mouse |
| Yukiko Ichihashi, Naonori Saito, Yoko Arakawa, Chika Kurata, Mitsuo Iinuma, Yasuo Tamura, Fumihiko Iwaku, Kin-Ya Kub. The bite-raised condition in aged SAMP8 mice reduces the expression of glucocorticoid receptors in the dorsal and ventral hippocampus. Okajimas folia anatomica Japonica. vol 84. issue 4. 2008-06-20. PMID:18464530. |
only in the dg subfield was there a significant difference in the number of gr-immunoreactive cells between the dorsal and ventral hippocampus. |
2008-06-20 |
2023-08-12 |
mouse |
| Chun-Yao Lee, Wen-Mei Fu, Chih-Chuan Chen, Ming-Jai Su, Horng-Huei Lio. Lamotrigine inhibits postsynaptic AMPA receptor and glutamate release in the dentate gyrus. Epilepsia. vol 49. issue 5. 2008-06-17. PMID:18248444. |
the dentate gyrus (dg) is a gateway that regulates seizure activity in the hippocampus. |
2008-06-17 |
2023-08-12 |
Not clear |
| Song Li, Che Wang, Wei Wang, Huiping Dong, Peng Hou, Yiyuan Tan. Chronic mild stress impairs cognition in mice: from brain homeostasis to behavior. Life sciences. vol 82. issue 17-18. 2008-06-17. PMID:18402983. |
in addition, severe neuronal cell damage was found, as bromodeoxyuridine (brdu) positive cells and the expression of brain derived neurotrophic factor (bdnf) in dentate gyrus (dg) of hippocampus were decreased after 5 weeks cms procedure. |
2008-06-17 |
2023-08-12 |
mouse |
| J Harry Blaise, Jessica L Koranda, Urey Chow, Kaitlin E Haines, Emily C Dorwar. Neonatal isolation stress alters bidirectional long-term synaptic plasticity in amygdalo-hippocampal synapses in freely behaving adult rats. Brain research. vol 1193. 2008-06-03. PMID:18178177. |
the basolateral amygdala (bla) is known to be involved in emotional and stress responses, while the dentate gyrus (dg), a subfield of the hippocampus, is implicated in learning and memory. |
2008-06-03 |
2023-08-12 |
rat |
| Daisuke Ibi, Kazuhiro Takuma, Hiroyuki Koike, Hiroyuki Mizoguchi, Katsuki Tsuritani, Yusuke Kuwahara, Hiroyuki Kamei, Taku Nagai, Yukio Yoneda, Toshitaka Nabeshima, Kiyofumi Yamad. Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice. Journal of neurochemistry. vol 105. issue 3. 2008-05-22. PMID:18182044. |
in this study, we examined the effect of si on neurogenesis in the hippocampal dentate gyrus (dg) relating to memory and emotion-related behaviors. |
2008-05-22 |
2023-08-12 |
mouse |
| Adám Fekete, E Sylvester Vizi, Krisztina J Kovács, Balázs Lendvai, Tibor Zelle. Layer-specific differences in reactive oxygen species levels after oxygen-glucose deprivation in acute hippocampal slices. Free radical biology & medicine. vol 44. issue 6. 2008-05-21. PMID:18206124. |
by using acute hippocampal slices and the fluorescent dye cm-h2dcfda, we showed that reoxygenation after in vitro ischemia (oxygen-glucose deprivation; ogd) increased ros levels in the hippocampal ca1 layers vulnerable to ischemia but did not have significant effects in the resistant stratum granulosum in the dentate gyrus (dg). |
2008-05-21 |
2023-08-12 |
Not clear |
| Adám Fekete, E Sylvester Vizi, Krisztina J Kovács, Balázs Lendvai, Tibor Zelle. Layer-specific differences in reactive oxygen species levels after oxygen-glucose deprivation in acute hippocampal slices. Free radical biology & medicine. vol 44. issue 6. 2008-05-21. PMID:18206124. |
direct visualization of layer-specific effects of ros production and its scavenging, shown for the first time in acute hippocampal slices, suggests that distinct ros homeostasis may underlie the different ischemic vulnerability of ca1 and dg. |
2008-05-21 |
2023-08-12 |
Not clear |
| Luciana Pietranera, Flavia E Saravia, Paulina Roig, Analia Lima, Alejandro F De Nicol. Protective effects of estradiol in the brain of rats with genetic or mineralocorticoid-induced hypertension. Psychoneuroendocrinology. vol 33. issue 3. 2008-05-13. PMID:18164826. |
in the hippocampus, changes include decreased cell proliferation in the dentate gyrus (dg), astrogliosis and decreased neuronal density in the hilus, whereas in the hypothalamus expression of arginine vasopressin (avp) is markedly elevated. |
2008-05-13 |
2023-08-12 |
rat |
| Xin Yu, Lianjun Guo, Guangfu Yin, Xiangang Zong, Yongxun A. Effect of non-specific HCN1 blocker CsCl on spatial learning and memory in mouse. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 26. issue 2. 2008-05-12. PMID:16850736. |
in hippocampal tissues, staining for the hcn1 mrna was stronger in the dg and ca1 region of the hippocampus (p <0.05, p<0.05, when cscl-administration group was compared with normal group). |
2008-05-12 |
2023-08-12 |
mouse |
| Joseph E Carpentino, Nathaniel W Hartman, Laura B Grabel, Janice R Naegel. Region-specific differentiation of embryonic stem cell-derived neural progenitor transplants into the adult mouse hippocampus following seizures. Journal of neuroscience research. vol 86. issue 3. 2008-04-28. PMID:17918739. |
hippocampal grafts in mice not subjected to seizures displayed a marked tendency to form tumors, and this effect was more pronounced in the dg than in the fimbria. |
2008-04-28 |
2023-08-12 |
mouse |
| Renaud Vandenbosch, Laurence Borgs, Pierre Beukelaers, Agnès Foidart, Laurent Nguyen, Gustave Moonen, Cyril Berthet, Philipp Kaldis, Vittorio Gallo, Shibeshih Belachew, Brigitte Malgrang. CDK2 is dispensable for adult hippocampal neurogenesis. Cell cycle (Georgetown, Tex.). vol 6. issue 24. 2008-04-28. PMID:18073538. |
granule neurons of the dentate gyrus (dg) of the hippocampus undergo continuous renewal throughout life. |
2008-04-28 |
2023-08-12 |
mouse |
| Jayne M Ness, Cary R Harvey, Jason D Washington, Kevin A Roth, Steven L Carroll, Jianhua Zhan. Differential activation of c-fos and caspase-3 in hippocampal neuron subpopulations following neonatal hypoxia-ischemia. Journal of neuroscience research. vol 86. issue 5. 2008-04-23. PMID:18030677. |
c-fos immunoreactivity increased throughout the injured hippocampus 3 hr after hi but became restricted to the ca2-3 subregion and the dentate gyrus (dg) at 6-12 hr and declined by 24 hr. |
2008-04-23 |
2023-08-12 |
mouse |
| Hongtao Wu, Dunyue Lu, Hao Jiang, Ye Xiong, Changsheng Qu, Bo Li, Asim Mahmood, Dong Zhou, Michael Chop. Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury. Journal of neurotrauma. vol 25. issue 2. 2008-04-15. PMID:18260796. |
this study was undertaken to evaluate the effect of simvastatin, a cholesterol-lowering agent, on the akt-mediated signaling pathway and neurogenesis in the dentate gyrus (dg) of the hippocampus in rats after traumatic brain injury (tbi). |
2008-04-15 |
2023-08-12 |
rat |
| Hongtao Wu, Dunyue Lu, Hao Jiang, Ye Xiong, Changsheng Qu, Bo Li, Asim Mahmood, Dong Zhou, Michael Chop. Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury. Journal of neurotrauma. vol 25. issue 2. 2008-04-15. PMID:18260796. |
these data suggest that the neurorestorative effect of simvastatin may be mediated through activation of the akt-mediated signaling pathway, subsequently upregulating expression of growth factors and inducing neurogenesis in the dg of the hippocampus, thereby leading to restoration of cognitive function after tbi in rats. |
2008-04-15 |
2023-08-12 |
rat |
| Norifumi Shioda, Motohiro Morioka, Kohji Fukunag. [Vanadium compounds enhance adult neurogenesis after brain ischemia]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 128. issue 3. 2008-04-15. PMID:18311061. |
in addition, newborn granule cells in the hippocampal dg are important for learning and memory formation. |
2008-04-15 |
2023-08-12 |
human |
| Min-Chi Hsiao, Chiu-Hsien Chan, Vijay Srinivasan, Ashish Ahuja, Gopal Erinjippurath, Theodoros P Zanos, Ghassan Gholmieh, Dong Song, Jack D Wills, Jeff LaCoss, Spiros Courellis, Armand R Tanguay, John J Granacki, Vasilis Z Marmarelis, Theodore W Berge. VLSI implementation of a nonlinear neuronal model: a "neural prosthesis" to restore hippocampal trisynaptic dynamics. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. vol 2006. 2008-04-02. PMID:17946244. |
the major intrinsic circuitry of the hippocampus consists of an excitatory cascade involving the dentate gyrus (dg), ca3, and ca1 subregions; this trisynaptic circuit can be maintained in a transverse slice preparation. |
2008-04-02 |
2023-08-12 |
Not clear |
| Min-Chi Hsiao, Chiu-Hsien Chan, Vijay Srinivasan, Ashish Ahuja, Gopal Erinjippurath, Theodoros P Zanos, Ghassan Gholmieh, Dong Song, Jack D Wills, Jeff LaCoss, Spiros Courellis, Armand R Tanguay, John J Granacki, Vasilis Z Marmarelis, Theodore W Berge. VLSI implementation of a nonlinear neuronal model: a "neural prosthesis" to restore hippocampal trisynaptic dynamics. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. vol 2006. 2008-04-02. PMID:17946244. |
our demonstration of a neural prosthesis for the hippocampal slice involves: (i) surgically removing ca3 function from the trisynaptic circuit by transecting ca3 axons, (ii) replacing biological ca3 function with a hardware vlsi (very large scale integration) model of the nonlinear dynamics of ca3, and (iii) through a specially designed multi-site electrode array, transmitting dg output to the hardware device, and routing the hardware device output to the synaptic inputs of the ca1 subregion, thus by-passing the damaged ca3. |
2008-04-02 |
2023-08-12 |
Not clear |