| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sandra Guidi, Paola Bonasoni, Claudio Ceccarelli, Donatella Santini, Fabio Gualtieri, Elisabetta Ciani, Renata Bartesagh. Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome. Brain pathology (Zurich, Switzerland). vol 18. issue 2. 2008-07-10. PMID:18093248. |
we previously obtained evidence for reduced cell proliferation in the dentate gyrus (dg) of fetuses with down syndrome (ds), suggesting that the hippocampal hypoplasia seen in adulthood may be caused by defective early neuron production. |
2008-07-10 |
2023-08-12 |
Not clear |
| Sandra Guidi, Paola Bonasoni, Claudio Ceccarelli, Donatella Santini, Fabio Gualtieri, Elisabetta Ciani, Renata Bartesagh. Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome. Brain pathology (Zurich, Switzerland). vol 18. issue 2. 2008-07-10. PMID:18093248. |
the goal of this study was to establish whether ds fetuses (17-21 weeks of gestation) exhibit reduction in total cell number in the dg, hippocampus and parahippocampal gyrus (phg). |
2008-07-10 |
2023-08-12 |
Not clear |
| Letizia Corsani, Elisa Bizzoco, Felicita Pedata, Marco Gianfriddo, Maria Simonetta Faussone-Pellegrini, Maria Giuliana Vannucch. Inducible nitric oxide synthase appears and is co-expressed with the neuronal isoform in interneurons of the rat hippocampus after transient ischemia induced by middle cerebral artery occlusion. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18436211. |
the hippocampus (dentate gyrus dg plus cornu ammonis, ca) is vulnerable to neuropathological events such as ischemia. |
2008-07-07 |
2023-08-12 |
rat |
| Letizia Corsani, Elisa Bizzoco, Felicita Pedata, Marco Gianfriddo, Maria Simonetta Faussone-Pellegrini, Maria Giuliana Vannucch. Inducible nitric oxide synthase appears and is co-expressed with the neuronal isoform in interneurons of the rat hippocampus after transient ischemia induced by middle cerebral artery occlusion. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18436211. |
no information is available on the presence of nnos-immunoreactive (ir) neurons in the hippocampus of ischemic animals; whereas, the presence of the inos protein has been reported in the dg after focal ischemia. |
2008-07-07 |
2023-08-12 |
rat |
| C J Peddie, H A Davies, F M Colyer, M G Stewart, J J Rodrígue. Colocalisation of serotonin2A receptors with the glutamate receptor subunits NR1 and GluR2 in the dentate gyrus: an ultrastructural study of a modulatory role. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18439999. |
here, we have conducted an electron microscopic examination of 5-ht(2a)r distribution with the glutamate n-methyl-d-aspartate (nmda) and amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (ampa) receptor subunits nr1 and glur2 in the hippocampal dentate gyrus (dg) in order to investigate whether 5-ht(2a)r location is compatible with a modulatory role over nmda and/or ampa receptor mediated neurotransmission. |
2008-07-07 |
2023-08-12 |
Not clear |
| Fang Yang, Jin-Cun Wang, Jun-Liang Han, Gang Zhao, Wen Jian. Different effects of mild and severe seizures on hippocampal neurogenesis in adult rats. Hippocampus. vol 18. issue 5. 2008-07-01. PMID:18240317. |
recent evidence shows that functional neurogenesis exists in the adult hippocampus and that epileptic seizures can increase neurogenesis in the dentate gyrus (dg). |
2008-07-01 |
2023-08-12 |
rat |
| Matthew Goddard, Yiwen Zheng, Cynthia L Darlington, Paul F Smit. Synaptic protein expression in the medial temporal lobe and frontal cortex following chronic bilateral vestibular loss. Hippocampus. vol 18. issue 5. 2008-07-01. PMID:18306302. |
in this study we investigated whether bvd in rats resulted in changes in the expression of four proteins related to neuronal plasticity, synaptophysin, snap-25, drebrin and neurofilament-l, in the hippocampal subregions (ca1, ca2/3, the dg) and the entorhinal (ec), perirhinal (prc) and frontal cortices (fc), using western blotting. |
2008-07-01 |
2023-08-12 |
rat |
| Naoko Kaneko, Kazunobu Sawamot. [Adult neurogenesis in physiological and pathological conditions]. Brain and nerve = Shinkei kenkyu no shinpo. vol 60. issue 4. 2008-06-26. PMID:18421973. |
generation of new neurons persists in the two restricted regions of adult brain, the dentate gyrus (dg) of the hippocampus and the subventricular zone (svz). |
2008-06-26 |
2023-08-12 |
Not clear |
| J Beauquis, F Saravia, J Coulaud, P Roig, M Dardenne, F Homo-Delarche, Alejandro De Nicol. Prominently decreased hippocampal neurogenesis in a spontaneous model of type 1 diabetes, the nonobese diabetic mouse. Experimental neurology. vol 210. issue 2. 2008-06-20. PMID:18190910. |
the number of proliferative brdu-positive cells in the dg was, regardless of age, constantly and significantly lower in nod than in control strains, showing the presence of hippocampal alterations far before clinical diabetes onset in nod mice. |
2008-06-20 |
2023-08-12 |
mouse |
| J Beauquis, F Saravia, J Coulaud, P Roig, M Dardenne, F Homo-Delarche, Alejandro De Nicol. Prominently decreased hippocampal neurogenesis in a spontaneous model of type 1 diabetes, the nonobese diabetic mouse. Experimental neurology. vol 210. issue 2. 2008-06-20. PMID:18190910. |
notably, nod hippocampal dg cell proliferation defect takes place during the prediabetic stage. |
2008-06-20 |
2023-08-12 |
mouse |
| Yukiko Ichihashi, Naonori Saito, Yoko Arakawa, Chika Kurata, Mitsuo Iinuma, Yasuo Tamura, Fumihiko Iwaku, Kin-Ya Kub. The bite-raised condition in aged SAMP8 mice reduces the expression of glucocorticoid receptors in the dorsal and ventral hippocampus. Okajimas folia anatomica Japonica. vol 84. issue 4. 2008-06-20. PMID:18464530. |
in the bite-raised condition, the number of gr-immunoreactive cells was significantly decreased in both the dorsal and ventral ca1 and dentate gyrus (dg) subfields of the hippocampus compared to control mice, as revealed by immunohistochemical analysis. |
2008-06-20 |
2023-08-12 |
mouse |
| Yukiko Ichihashi, Naonori Saito, Yoko Arakawa, Chika Kurata, Mitsuo Iinuma, Yasuo Tamura, Fumihiko Iwaku, Kin-Ya Kub. The bite-raised condition in aged SAMP8 mice reduces the expression of glucocorticoid receptors in the dorsal and ventral hippocampus. Okajimas folia anatomica Japonica. vol 84. issue 4. 2008-06-20. PMID:18464530. |
only in the dg subfield was there a significant difference in the number of gr-immunoreactive cells between the dorsal and ventral hippocampus. |
2008-06-20 |
2023-08-12 |
mouse |
| Chun-Yao Lee, Wen-Mei Fu, Chih-Chuan Chen, Ming-Jai Su, Horng-Huei Lio. Lamotrigine inhibits postsynaptic AMPA receptor and glutamate release in the dentate gyrus. Epilepsia. vol 49. issue 5. 2008-06-17. PMID:18248444. |
the dentate gyrus (dg) is a gateway that regulates seizure activity in the hippocampus. |
2008-06-17 |
2023-08-12 |
Not clear |
| Song Li, Che Wang, Wei Wang, Huiping Dong, Peng Hou, Yiyuan Tan. Chronic mild stress impairs cognition in mice: from brain homeostasis to behavior. Life sciences. vol 82. issue 17-18. 2008-06-17. PMID:18402983. |
in addition, severe neuronal cell damage was found, as bromodeoxyuridine (brdu) positive cells and the expression of brain derived neurotrophic factor (bdnf) in dentate gyrus (dg) of hippocampus were decreased after 5 weeks cms procedure. |
2008-06-17 |
2023-08-12 |
mouse |
| J Harry Blaise, Jessica L Koranda, Urey Chow, Kaitlin E Haines, Emily C Dorwar. Neonatal isolation stress alters bidirectional long-term synaptic plasticity in amygdalo-hippocampal synapses in freely behaving adult rats. Brain research. vol 1193. 2008-06-03. PMID:18178177. |
the basolateral amygdala (bla) is known to be involved in emotional and stress responses, while the dentate gyrus (dg), a subfield of the hippocampus, is implicated in learning and memory. |
2008-06-03 |
2023-08-12 |
rat |
| Daisuke Ibi, Kazuhiro Takuma, Hiroyuki Koike, Hiroyuki Mizoguchi, Katsuki Tsuritani, Yusuke Kuwahara, Hiroyuki Kamei, Taku Nagai, Yukio Yoneda, Toshitaka Nabeshima, Kiyofumi Yamad. Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice. Journal of neurochemistry. vol 105. issue 3. 2008-05-22. PMID:18182044. |
in this study, we examined the effect of si on neurogenesis in the hippocampal dentate gyrus (dg) relating to memory and emotion-related behaviors. |
2008-05-22 |
2023-08-12 |
mouse |
| Adám Fekete, E Sylvester Vizi, Krisztina J Kovács, Balázs Lendvai, Tibor Zelle. Layer-specific differences in reactive oxygen species levels after oxygen-glucose deprivation in acute hippocampal slices. Free radical biology & medicine. vol 44. issue 6. 2008-05-21. PMID:18206124. |
by using acute hippocampal slices and the fluorescent dye cm-h2dcfda, we showed that reoxygenation after in vitro ischemia (oxygen-glucose deprivation; ogd) increased ros levels in the hippocampal ca1 layers vulnerable to ischemia but did not have significant effects in the resistant stratum granulosum in the dentate gyrus (dg). |
2008-05-21 |
2023-08-12 |
Not clear |
| Adám Fekete, E Sylvester Vizi, Krisztina J Kovács, Balázs Lendvai, Tibor Zelle. Layer-specific differences in reactive oxygen species levels after oxygen-glucose deprivation in acute hippocampal slices. Free radical biology & medicine. vol 44. issue 6. 2008-05-21. PMID:18206124. |
direct visualization of layer-specific effects of ros production and its scavenging, shown for the first time in acute hippocampal slices, suggests that distinct ros homeostasis may underlie the different ischemic vulnerability of ca1 and dg. |
2008-05-21 |
2023-08-12 |
Not clear |
| Luciana Pietranera, Flavia E Saravia, Paulina Roig, Analia Lima, Alejandro F De Nicol. Protective effects of estradiol in the brain of rats with genetic or mineralocorticoid-induced hypertension. Psychoneuroendocrinology. vol 33. issue 3. 2008-05-13. PMID:18164826. |
in the hippocampus, changes include decreased cell proliferation in the dentate gyrus (dg), astrogliosis and decreased neuronal density in the hilus, whereas in the hypothalamus expression of arginine vasopressin (avp) is markedly elevated. |
2008-05-13 |
2023-08-12 |
rat |
| Xin Yu, Lianjun Guo, Guangfu Yin, Xiangang Zong, Yongxun A. Effect of non-specific HCN1 blocker CsCl on spatial learning and memory in mouse. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 26. issue 2. 2008-05-12. PMID:16850736. |
in hippocampal tissues, staining for the hcn1 mrna was stronger in the dg and ca1 region of the hippocampus (p <0.05, p<0.05, when cscl-administration group was compared with normal group). |
2008-05-12 |
2023-08-12 |
mouse |