| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joseph E Carpentino, Nathaniel W Hartman, Laura B Grabel, Janice R Naegel. Region-specific differentiation of embryonic stem cell-derived neural progenitor transplants into the adult mouse hippocampus following seizures. Journal of neuroscience research. vol 86. issue 3. 2008-04-28. PMID:17918739. |
hippocampal grafts in mice not subjected to seizures displayed a marked tendency to form tumors, and this effect was more pronounced in the dg than in the fimbria. |
2008-04-28 |
2023-08-12 |
mouse |
| Renaud Vandenbosch, Laurence Borgs, Pierre Beukelaers, Agnès Foidart, Laurent Nguyen, Gustave Moonen, Cyril Berthet, Philipp Kaldis, Vittorio Gallo, Shibeshih Belachew, Brigitte Malgrang. CDK2 is dispensable for adult hippocampal neurogenesis. Cell cycle (Georgetown, Tex.). vol 6. issue 24. 2008-04-28. PMID:18073538. |
granule neurons of the dentate gyrus (dg) of the hippocampus undergo continuous renewal throughout life. |
2008-04-28 |
2023-08-12 |
mouse |
| Jayne M Ness, Cary R Harvey, Jason D Washington, Kevin A Roth, Steven L Carroll, Jianhua Zhan. Differential activation of c-fos and caspase-3 in hippocampal neuron subpopulations following neonatal hypoxia-ischemia. Journal of neuroscience research. vol 86. issue 5. 2008-04-23. PMID:18030677. |
c-fos immunoreactivity increased throughout the injured hippocampus 3 hr after hi but became restricted to the ca2-3 subregion and the dentate gyrus (dg) at 6-12 hr and declined by 24 hr. |
2008-04-23 |
2023-08-12 |
mouse |
| Hongtao Wu, Dunyue Lu, Hao Jiang, Ye Xiong, Changsheng Qu, Bo Li, Asim Mahmood, Dong Zhou, Michael Chop. Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury. Journal of neurotrauma. vol 25. issue 2. 2008-04-15. PMID:18260796. |
this study was undertaken to evaluate the effect of simvastatin, a cholesterol-lowering agent, on the akt-mediated signaling pathway and neurogenesis in the dentate gyrus (dg) of the hippocampus in rats after traumatic brain injury (tbi). |
2008-04-15 |
2023-08-12 |
rat |
| Hongtao Wu, Dunyue Lu, Hao Jiang, Ye Xiong, Changsheng Qu, Bo Li, Asim Mahmood, Dong Zhou, Michael Chop. Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury. Journal of neurotrauma. vol 25. issue 2. 2008-04-15. PMID:18260796. |
these data suggest that the neurorestorative effect of simvastatin may be mediated through activation of the akt-mediated signaling pathway, subsequently upregulating expression of growth factors and inducing neurogenesis in the dg of the hippocampus, thereby leading to restoration of cognitive function after tbi in rats. |
2008-04-15 |
2023-08-12 |
rat |
| Norifumi Shioda, Motohiro Morioka, Kohji Fukunag. [Vanadium compounds enhance adult neurogenesis after brain ischemia]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 128. issue 3. 2008-04-15. PMID:18311061. |
in addition, newborn granule cells in the hippocampal dg are important for learning and memory formation. |
2008-04-15 |
2023-08-12 |
human |
| Min-Chi Hsiao, Chiu-Hsien Chan, Vijay Srinivasan, Ashish Ahuja, Gopal Erinjippurath, Theodoros P Zanos, Ghassan Gholmieh, Dong Song, Jack D Wills, Jeff LaCoss, Spiros Courellis, Armand R Tanguay, John J Granacki, Vasilis Z Marmarelis, Theodore W Berge. VLSI implementation of a nonlinear neuronal model: a "neural prosthesis" to restore hippocampal trisynaptic dynamics. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. vol 2006. 2008-04-02. PMID:17946244. |
the major intrinsic circuitry of the hippocampus consists of an excitatory cascade involving the dentate gyrus (dg), ca3, and ca1 subregions; this trisynaptic circuit can be maintained in a transverse slice preparation. |
2008-04-02 |
2023-08-12 |
Not clear |
| Min-Chi Hsiao, Chiu-Hsien Chan, Vijay Srinivasan, Ashish Ahuja, Gopal Erinjippurath, Theodoros P Zanos, Ghassan Gholmieh, Dong Song, Jack D Wills, Jeff LaCoss, Spiros Courellis, Armand R Tanguay, John J Granacki, Vasilis Z Marmarelis, Theodore W Berge. VLSI implementation of a nonlinear neuronal model: a "neural prosthesis" to restore hippocampal trisynaptic dynamics. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. vol 2006. 2008-04-02. PMID:17946244. |
our demonstration of a neural prosthesis for the hippocampal slice involves: (i) surgically removing ca3 function from the trisynaptic circuit by transecting ca3 axons, (ii) replacing biological ca3 function with a hardware vlsi (very large scale integration) model of the nonlinear dynamics of ca3, and (iii) through a specially designed multi-site electrode array, transmitting dg output to the hardware device, and routing the hardware device output to the synaptic inputs of the ca1 subregion, thus by-passing the damaged ca3. |
2008-04-02 |
2023-08-12 |
Not clear |
| Ruben Guzman-Marin, Natalia Suntsova, Tariq Bashir, Robert Nienhuis, Ronald Szymusiak, Dennis McGint. Rapid eye movement sleep deprivation contributes to reduction of neurogenesis in the hippocampal dentate gyrus of the adult rat. Sleep. vol 31. issue 2. 2008-04-02. PMID:18274263. |
the dentate gyrus (dg) of the adult hippocampus contains progenitor cells, which have potential to differentiate into neurons. |
2008-04-02 |
2023-08-12 |
rat |
| F A Konopacki, M Rylski, E Wilczek, R Amborska, D Detka, L Kaczmarek, G M Wilczynsk. Synaptic localization of seizure-induced matrix metalloproteinase-9 mRNA. Neuroscience. vol 150. issue 1. 2008-03-28. PMID:17928157. |
it was recently shown to be prominently up-regulated in the hippocampal dentate gyrus (dg) upon kainate-mediated seizures. |
2008-03-28 |
2023-08-12 |
rat |
| Jung-Mi Han, Byung-Joon Chang, Tian-Zhu Li, Nong-Hoon Choe, Fu-Shi Quan, Bong-Jun Jang, Ik-Hyun Cho, Hea-Nam Hong, Jong-Hwan Le. Protective effects of ascorbic acid against lead-induced apoptotic neurodegeneration in the developing rat hippocampus in vivo. Brain research. vol 1185. 2008-03-28. PMID:17959157. |
histopathological evaluation demonstrated that ascorbic acid significantly attenuates apoptosis in the developing hippocampus and also spares hippocampal ca1, ca3 and dentate gyrus (dg) neurons. |
2008-03-28 |
2023-08-12 |
rat |
| Bharathi Hattiangady, Muddanna S Rao, Ashok K Shett. Plasticity of hippocampal stem/progenitor cells to enhance neurogenesis in response to kainate-induced injury is lost by middle age. Aging cell. vol 7. issue 2. 2008-03-28. PMID:18241325. |
to ascertain whether this plasticity is preserved during aging, we quantified dg neurogenesis in the young adult, middle-aged and aged f344 rats after kainic acid induced hippocampal injury. |
2008-03-28 |
2023-08-12 |
rat |
| Bharathi Hattiangady, Muddanna S Rao, Ashok K Shett. Plasticity of hippocampal stem/progenitor cells to enhance neurogenesis in response to kainate-induced injury is lost by middle age. Aging cell. vol 7. issue 2. 2008-03-28. PMID:18241325. |
thus, hippocampal injury does not adequately stimulate nscs in the middle-aged and aged dg, resulting in no changes in neurogenesis after injury. |
2008-03-28 |
2023-08-12 |
rat |
| David B Jaffe, Rafael Gutiérre. Mossy fiber synaptic transmission: communication from the dentate gyrus to area CA3. Progress in brain research. vol 163. 2008-03-14. PMID:17765714. |
communication between the dentate gyrus (dg) and area ca3 of the hippocampus proper is transmitted via axons of granule cells--the mossy fiber (mf) pathway. |
2008-03-14 |
2023-08-12 |
Not clear |
| Brennan D Eadie, Van A Redila, Brian R Christi. Voluntary exercise alters the cytoarchitecture of the adult dentate gyrus by increasing cellular proliferation, dendritic complexity, and spine density. The Journal of comparative neurology. vol 486. issue 1. 2008-03-13. PMID:15834963. |
the dramatic changes in the cytoarchitecture of the dg induced by voluntary exercise might underlie the enhancement of hippocampal long-term potentiation and hippocampal-dependent memory that our group has previously described. |
2008-03-13 |
2023-08-12 |
rat |
| Michael G Ruscio, Timothy D Sweeny, Julie L Hazelton, Patrin Suppatkul, Emily Boothe, C Sue Carte. Pup exposure elicits hippocampal cell proliferation in the prairie vole. Behavioural brain research. vol 187. issue 1. 2008-03-11. PMID:17913255. |
in the present experiment, we exposed adult male and female prairie voles (microtus ochrogaster) to two foster pups for 20 min and quantified cell proliferation in the dentate gyrus of the hippocampus (dg), medial amygdala (mea) and cortical amygdala (cora). |
2008-03-11 |
2023-08-12 |
Not clear |
| Esmaeil Akbari, Fereshteh Motamedi, Nasser Naghdi, Maryam Noorbakhshni. The effect of antagonization of orexin 1 receptors in CA1 and dentate gyrus regions on memory processing in passive avoidance task. Behavioural brain research. vol 187. issue 1. 2008-03-11. PMID:17977608. |
we have previously demonstrated that antagonization of orexin 1 receptor (ox1r) in ca1 region of hippocampus and dentate gyrus (dg) impaired spatial memory processing. |
2008-03-11 |
2023-08-12 |
rat |
| Esmaeil Akbari, Fereshteh Motamedi, Nasser Naghdi, Maryam Noorbakhshni. The effect of antagonization of orexin 1 receptors in CA1 and dentate gyrus regions on memory processing in passive avoidance task. Behavioural brain research. vol 187. issue 1. 2008-03-11. PMID:17977608. |
to address this, the ox1r antagonist, sb-334867-a, was injected into dg or ca1 regions of hippocampus and evaluated the influence of ox1r antagonization on acquisition, consolidation and retrieval in pa task. |
2008-03-11 |
2023-08-12 |
rat |
| J E Cohen, G Zimmerman, N Melamed-Book, A Friedman, A Dori, H Sore. Transgenic inactivation of acetylcholinesterase impairs homeostasis in mouse hippocampal granule cells. Hippocampus. vol 18. issue 2. 2008-03-03. PMID:17960645. |
in the adult murine hippocampus, dentate gyrus (dg), neurogenesis and neural cell death are thought to affect learning and memory in incompletely understood mechanism(s). |
2008-03-03 |
2023-08-12 |
mouse |
| J E Cohen, G Zimmerman, N Melamed-Book, A Friedman, A Dori, H Sore. Transgenic inactivation of acetylcholinesterase impairs homeostasis in mouse hippocampal granule cells. Hippocampus. vol 18. issue 2. 2008-03-03. PMID:17960645. |
our findings suggest that replacement of ache-s with ache-r serves to maintain dg homeostasis and associated cognitive tasks, highlighting the role of cholinergic signaling in adult hippocampal neurogenesis and functioning. |
2008-03-03 |
2023-08-12 |
mouse |