| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Muhammad M Hossain, Abdelmadjid Belkadi, Sara Al-Haddad, Jason R Richardso. Deltamethrin Exposure Inhibits Adult Hippocampal Neurogenesis and Causes Deficits in Learning and Memory in Mice. Toxicological sciences : an official journal of the Society of Toxicology. vol 178. issue 2. 2021-08-13. PMID:32976580. |
recent studies demonstrate that adult born neurons in the dentate gyrus (dg) in the hippocampus can functionally integrate into the existing neuronal circuitry and contribute to hippocampal-dependent learning and memory. |
2021-08-13 |
2023-08-13 |
mouse |
| I V Kastyro, I V Reshetov, G V Khamidulin, S S Shilin, V I Torshin, M G Kostyaeva, V I Popadyuk, T Y Yunusov, P E Shmaevsky, K P Shalamov, A D Kupryakova, E S Doroginskaya, A D Sedelnikov. Influence of Surgical Trauma in the Nasal Cavity on the Expression of p53 Protein in the Hippocampus of Rats. Doklady. Biochemistry and biophysics. vol 497. issue 1. 2021-08-13. PMID:33895923. |
a quantitative assessment of the apoptosis of neurons in the pyramidal layer of the hippocampus in the subfields ca1, ca2, ca3, and dentate gyrus (dg) on days 2, 4, and 6 after surgery was carried out. |
2021-08-13 |
2023-08-13 |
rat |
| Hao Wu, Yong Liu, Lishuo Liu, Qiang Meng, Changwang Du, Kuo Li, Shan Dong, Yong Zhang, Huanfa Li, Hua Zhan. Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34261484. |
knockout of bmal1 in hippocampal dentate gyrus (dg) neurons of bmal1 |
2021-08-12 |
2023-08-13 |
human |
| Meng Jia, Xuewei Wang, Haolin Zhang, Xinjuan Wang, Hui Ma, Mingda Yang, Yijing Li, Cailian Cu. MicroRNA-132 is involved in morphine dependence via modifying the structural plasticity of the dentate gyrus neurons in rats. Addiction biology. 2021-08-12. PMID:34382313. |
here, we investigate whether mir-132 is involved in morphine dependence and whether it is related to the structural plasticity of the dentate gyrus (dg) neurons. |
2021-08-12 |
2023-08-13 |
rat |
| Victor Rodrigues Santos, Igor Santana Melo, Amanda Larissa Dias Pacheco, Olagide Wagner de Castr. Life and death in the hippocampus: What's bad? Epilepsy & behavior : E&B. vol 121. issue Pt B. 2021-08-11. PMID:31759972. |
classically, neurodegeneration affects sensitive areas of the hippocampus, such as dentate gyrus (dg) hilus, as well as specific fields of the ammon's horn, ca3, and ca1. |
2021-08-11 |
2023-08-13 |
Not clear |
| Priya Gami-Patel, Irene van Dijken, Lieke H Meeter, Shamiram Melhem, Tjado H J Morrema, Wiep Scheper, John C van Swieten, Annemieke J M Rozemuller, Anke A Dijkstra, Jeroen J M Hoozeman. Unfolded protein response activation in C9orf72 frontotemporal dementia is associated with dipeptide pathology and granulovacuolar degeneration in granule cells. Brain pathology (Zurich, Switzerland). vol 31. issue 1. 2021-08-11. PMID:32865835. |
in the hippocampus, overall levels of pperk and peif2α were higher in c9-ftd, including in granule cells of the dentate gyrus (dg). |
2021-08-11 |
2023-08-13 |
human |
| Cristian Morales, Juan Facundo Morici, Nelson Espinosa, Agostina Sacson, Ariel Lara-Vasquez, M A García-Pérez, Pedro Bekinschtein, Noelia V Weisstaub, Pablo Fuentealb. Dentate Gyrus Somatostatin Cells are Required for Contextual Discrimination During Episodic Memory Encoding. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 2. 2021-08-11. PMID:33026440. |
this problem is solved by pattern separation, implemented in the dentate gyrus (dg) by granule cells to support episodic memory formation. |
2021-08-11 |
2023-08-13 |
mouse |
| Ohad Rechnitz, Inna Slutsky, Genela Morris, Dori Derdikma. Hippocampal sub-networks exhibit distinct spatial representation deficits in Alzheimer's disease model mice. Current biology : CB. vol 31. issue 15. 2021-08-11. PMID:34146487. |
not much is known about how the dentate gyrus (dg) and hippocampal ca3 networks, critical for memory and spatial processing, malfunction in alzheimer's disease (ad). |
2021-08-11 |
2023-08-13 |
mouse |
| Elham Taha, Sudarshan Patil, Iliana Barrera, Julia Panov, Mohammad Khamaisy, Christopher G Proud, Clive R Bramham, Kobi Rosenblu. eEF2/eEF2K Pathway in the Mature Dentate Gyrus Determines Neurogenesis Level and Cognition. Current biology : CB. vol 30. issue 18. 2021-08-09. PMID:32707059. |
levels of adult neurogenesis in the dentate gyrus (dg) of the hippocampus are correlated with unique cognitive functions. |
2021-08-09 |
2023-08-13 |
mouse |
| Yinghao Yu, Alan Bohan He, Michelle Liou, Chenyin Ou, Anna Kozłowska, Pingwen Chen, Andrew Chihwei Huan. The Paradoxical Effect Hypothesis of Abused Drugs in a Rat Model of Chronic Morphine Administration. Journal of clinical medicine. vol 10. issue 15. 2021-08-09. PMID:34361981. |
for assessments of c-fos and p-erk expression, the cingulate cortex 1 (cg1), prelimbic cortex (prl), infralimbic cortex (il), basolateral amygdala (bla), nucleus accumbens (nac), and dentate gyrus (dg) were involved in the morphine-induced cta, and resulted from the aversive effect of morphine on conditioning and reinstatement. |
2021-08-09 |
2023-08-13 |
rat |
| Dimitrios Andreou, Kjetil Nordbø Jørgensen, Stener Nerland, Kristine Engen, Robert H Yolken, Ole A Andreassen, Ingrid Agart. Cytomegalovirus infection associated with smaller dentate gyrus in men with severe mental illness. Brain, behavior, and immunity. vol 96. 2021-08-06. PMID:34010712. |
neural progenitor/stem cells are main cmv targets, and dentate gyrus (dg) a major neurogenic niche. |
2021-08-06 |
2023-08-13 |
Not clear |
| Stav Regev-Tsur, Yunus Emre Demiray, Kuldeep Tripathi, Oliver Stork, Gal Richter-Levin, Anne Albrech. Region-specific involvement of interneuron subpopulations in trauma-related pathology and resilience. Neurobiology of disease. vol 143. 2021-08-05. PMID:32561495. |
analyzing the activation of specific interneuron subpopulations in the dorsal and ventral dentate gyrus (dg), the basolateral (bla) and central amygdala by immunohistochemical double-labeling for cfos and different interneuron markers, revealed an increased activation of cholecystokinin (cck)-positive interneurons in the ventral dg, together with increased activation of parvalbumin- and cck-positive interneurons in the bla of affected trauma-exposed rats. |
2021-08-05 |
2023-08-13 |
rat |
| Xin Zhang, Yue Hei, Wei Bai, Tao Huang, Enming Kang, Huijun Chen, Chuiguang Kong, Yongxiang Yang, Yuqin Ye, Xiaosheng H. Toll-Like Receptor 2 Attenuates Traumatic Brain Injury-Induced Neural Stem Cell Proliferation in Dentate Gyrus of Rats. Neural plasticity. vol 2020. 2021-08-03. PMID:32879625. |
the current study investigated the correlation of tlr2 and nsc proliferation in the dentate gyrus (dg) using the tbi model of rats. |
2021-08-03 |
2023-08-13 |
rat |
| Ruxin Xie, Zhongke Wang, Tianyao Liu, Rui Xiao, Keyi Lv, Chuan Wu, Yi Luo, Yun Cai, Xiaotang Fa. AAV Delivery of shRNA Against TRPC6 in Mouse Hippocampus Impairs Cognitive Function. Frontiers in cell and developmental biology. vol 9. 2021-07-31. PMID:34327201. |
gene silencing of trpc6 was performed by injecting adeno-associated virus (aav) expressing trpc6-specific shrna (shrna-trpc6) into the hippocampal dentate gyrus (dg). |
2021-07-31 |
2023-08-13 |
mouse |
| David Alcantara-Gonzalez, Elissavet Chartampila, Chiara Criscuolo, Helen E Scharfma. Early changes in synaptic and intrinsic properties of dentate gyrus granule cells in a mouse model of Alzheimer's disease neuropathology and atypical effects of the cholinergic antagonist atropine. Neurobiology of disease. vol 152. 2021-07-30. PMID:33484828. |
several studies have suggested that the hippocampal dentate gyrus (dg) may be an important area where hyperexcitability occurs. |
2021-07-30 |
2023-08-13 |
mouse |
| Ozlem Tugce Cilingir-Kaya, Cynthia Moore, Charles Kenneth Meshul, Duygu Gursoy, Filiz Onat, Serap Sirvanc. Neurogenesis is Enhanced in Young Rats with Genetic Absence Epilepsy: An Immuno-electron Microscopic Study. Turkish neurosurgery. vol 31. issue 4. 2021-07-30. PMID:33978223. |
to investigate neurogenesis in both adult and 3-week-old genetic absence epilepsy rats from strasbourg (gaers) to determine if newly formed neurons within the dentate gyrus (dg) form synaptic contacts with gabaergic (gamma aminobutyric acid) and glutamatergic nerve terminals and compared to the control (non-gaers) wistar rats. |
2021-07-30 |
2023-08-13 |
rat |
| Pim R A Heckman, Femke Roig Kuhn, Frank Raven, Youri G Bolsius, Jos Prickaerts, Peter Meerlo, Robbert Haveke. Phosphodiesterase inhibitors roflumilast and vardenafil prevent sleep deprivation-induced deficits in spatial pattern separation. Synapse (New York, N.Y.). vol 74. issue 6. 2021-07-29. PMID:32056276. |
in the present study, we assessed in mice whether sd also affects spatial pattern separation, a cognitive process that specifically requires the dentate gyrus (dg) subregion of the hippocampus. |
2021-07-29 |
2023-08-13 |
mouse |
| Lei Zhang, Yankai Jiang, Jie Zhu, Huazheng Liang, Xiangyang He, Jiahong Qian, Hai Lin, Yubo Tao, Keqing Zh. Quantitative Assessment of Hippocampal Tau Pathology in AD and PART. Journal of molecular neuroscience : MN. vol 70. issue 11. 2021-07-29. PMID:32372343. |
in ad cases, tau pathology was high in both ca1 and subiculum, followed by ca2/3, entorhinal cortex (ec), ca4, and dentate gyrus (dg). |
2021-07-29 |
2023-08-13 |
Not clear |
| Ye Li, Cuiqin Fan, Rui Gao, Tian Lan, Wenjing Wang, Shu Yan Y. Hippocampal miR-211-5p regulates neurogenesis and depression-like behaviors in the rat. Neuropharmacology. vol 194. 2021-07-28. PMID:34062164. |
in the present study, we screened mirna expression profiles and found that mir-211-5p was significantly down-regulated within the dentate gyrus (dg) hippocampus in the chronic unpredictable mild stress (cums) induced rat model of depression. |
2021-07-28 |
2023-08-13 |
rat |
| Poornima D E Weerasinghe-Mudiyanselage, Mary Jasmin Ang, Mai Wada, Sung-Ho Kim, Taekyun Shin, Miyoung Yang, Changjong Moo. Acute MPTP Treatment Impairs Dendritic Spine Density in the Mouse Hippocampus. Brain sciences. vol 11. issue 7. 2021-07-27. PMID:34201837. |
golgi staining showed that acute mptp treatment significantly reduced the spine density of neuronal dendrites in the cornu ammonis 1 (ca1) apical/basal and dentate gyrus (dg) subregions of the mouse hippocampus at 8 and 16 days after treatment, although it did not affect dendritic complexity (e.g., number of crossing dendrites, total dendritic length, and branch points per neuron) in both ca1 and dg subregions at all time points after treatment. |
2021-07-27 |
2023-08-13 |
mouse |