| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yucen Xia, Zhiqing Zhang, Weipeng Lin, Jinglan Yan, Chuan'an Zhu, Dongmin Yin, Su He, Yang Su, Nenggui Xu, Robert William Caldwell, Lin Yao, Yongjun Che. Modulating microglia activation prevents maternal immune activation induced schizophrenia-relevant behavior phenotypes via arginase 1 in the dentate gyrus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 11. 2021-06-23. PMID:32599605. |
we found fewer parvalbumin positive (pv+) cells and impaired gabaergic transmission in the dentate gyrus (dg), accompanied by schizophrenia-like behavior in the adult offspring. |
2021-06-23 |
2023-08-13 |
mouse |
| Christoph Anacker, Ezra Sydnor, Briana K Chen, Christina C LaGamma, Josephine C McGowan, Alessia Mastrodonato, Holly C Hunsberger, Ryan Shores, Rushell S Dixon, Bruce S McEwen, William Byne, Heino F L Meyer-Bahlburg, Walter Bockting, Anke A Ehrhardt, Christine A Denn. Behavioral and neurobiological effects of GnRH agonist treatment in mice-potential implications for puberty suppression in transgender individuals. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 5. 2021-06-23. PMID:32919399. |
neuronal hyperactivity was found in the dentate gyrus (dg) of leuprolide-treated females, but not males, consistent with the elevation in hyponeophagia and despair-like behavior in females. |
2021-06-23 |
2023-08-13 |
mouse |
| Samuel Domínguez-García, Ricardo Gómez-Oliva, Noelia Geribaldi-Doldán, Carmen Hierro-Bujalance, Marta Sendra, Félix A Ruiz, Livia Carrascal, Antonio J Macías-Sánchez, Cristina Verástegui, Rosario Hernández-Galán, Mónica García-Alloza, Pedro Nunez-Abades, Carmen Castr. Effects of classical PKC activation on hippocampal neurogenesis and cognitive performance: mechanism of action. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 6. 2021-06-23. PMID:33335309. |
new neurons generated from neural stem cells (nsc) within the dentate gyrus of the hippocampus (dg) integrate in hippocampal circuitry participating in memory tasks. |
2021-06-23 |
2023-08-13 |
mouse |
| Saskia B J Koch, Vanessa A van Ast, Reinoud Kaldewaij, Mahur M Hashemi, Wei Zhang, Floris Klumpers, Karin Roelof. Larger dentate gyrus volume as predisposing resilience factor for the development of trauma-related symptoms. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 7. 2021-06-23. PMID:33479507. |
smaller hippocampal left dentate gyrus (dg) volumes at baseline predicted increase in self-reported ptsd symptoms (b[se] = -0.21[0.08], p = 0.011), stress symptoms (b[se] = -0.16[0.07], p = 0.024) and negative affect (b[se] = -0.21[0.07], p = 0.005) upon trauma exposure. |
2021-06-23 |
2023-08-13 |
Not clear |
| S S Sorokina, A E Malkov, L V Shubina, S I Zaichkina, V A Pikalo. Low dose of carbon ion irradiation induces early delayed cognitive impairments in mice. Radiation and environmental biophysics. vol 60. issue 1. 2021-06-22. PMID:33392787. |
nissl staining revealed a reduction in the number of cells in the dorsal hippocampus of irradiated mice, with the most pronounced reduction in cell density observed in the dentate gyrus (dg) hilus. |
2021-06-22 |
2023-08-13 |
mouse |
| Kimia RayatSanati, Shole Jamali, Amir Arash Hassanlou, Abbas Haghparas. Blockade of orexin receptors in the hippocampal dentate gyrus reduced the extinction latency of morphine-induced place preference in male rats. Neuroscience letters. vol 756. 2021-06-22. PMID:33974952. |
the dentate gyrus (dg) of the hippocampus receives orexinergic projections from the lateral hypothalamus that has been approved as a critical area arbitrating the maintenance of drug-seeking behavior following the extinction. |
2021-06-22 |
2023-08-13 |
rat |
| Hossein Khaleghzadeh-Ahangar, Mina Rashvand, Abbas Haghparas. Role of D1- and D2-like dopamine receptors within the dentate gyrus in antinociception induced by chemical stimulation of the lateral hypothalamus in an animal model of acute pain. Physiology & behavior. vol 229. 2021-06-21. PMID:33091437. |
the dentate gyrus (dg) as the main gateway of the hippocampal formation (hf) plays a crucial role in pain modulation. |
2021-06-21 |
2023-08-13 |
rat |
| Yangsik Kim, Jung Sun Lee, Yeon Ho Jo. Rapamycin increases the incidence of neuropsychiatric illness in kidney transplant patients through the suppression of neural stem cells. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32424120. |
in these rapamycin-treated mice also, the granule cells in the dentate gyrus (dg), which actively differentiate and proliferate from nsc, showed decreases in both excitatory and inhibitory synaptic transmission. |
2021-06-18 |
2023-08-13 |
mouse |
| Shunya Yagi, Jared E J Splinter, Daria Tai, Sarah Wong, Yanhua Wen, Liisa A M Gale. Sex Differences in Maturation and Attrition of Adult Neurogenesis in the Hippocampus. eNeuro. vol 7. issue 4. 2021-06-18. PMID:32586842. |
here, we investigated the trajectory and maturation rate of adult-born neurons in the dentate gyrus (dg) of male and female rats. |
2021-06-18 |
2023-08-13 |
rat |
| Sinead Rooney, Anupam Sah, Michael S Unger, Maria Kharitonova, Simone B Sartori, Christoph Schwarzer, Ludwig Aigner, Helmut Kettenmann, Susanne A Wolf, Nicolas Singewal. Neuroinflammatory alterations in trait anxiety: modulatory effects of minocycline. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32732969. |
in particular, the dentate gyrus (dg) of the hippocampus of habs exhibited enhanced density and average cell area of iba1+, and density of phagocytic (cd68+/iba1+) microglia compared to normal anxiety (nab) controls. |
2021-06-18 |
2023-08-13 |
mouse |
| Andrea Du Preez, Thomas Law, Diletta Onorato, Yau M Lim, Paola Eiben, Ksenia Musaelyan, Martin Egeland, Abdul Hye, Patricia A Zunszain, Sandrine Thuret, Carmine M Pariante, Cathy Fernande. The type of stress matters: repeated injection and permanent social isolation stress in male mice have a differential effect on anxiety- and depressive-like behaviours, and associated biological alterations. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32958745. |
exposure to 6 weeks of repeated injection resulted in an anxiety-like phenotype, decreased systemic inflammation (i.e., reduced plasma levels of tnfα and il4), increased corticosterone reactivity, increased microglial activation and decreased neuronal differentiation in the dentate gyrus (dg). |
2021-06-18 |
2023-08-13 |
mouse |
| Kaitlin A Folweiler, Guoxiang Xiong, Kaitlin M Best, Hannah E Metheny, Gabriel Nah, Akiva S Cohe. Traumatic Brain Injury Diminishes Feedforward Activation of Parvalbumin-Expressing Interneurons in the Dentate Gyrus. eNeuro. vol 7. issue 6. 2021-06-18. PMID:33106385. |
traumatic brain injury (tbi) is associated with aberrant network hyperexcitability in the dentate gyrus (dg). |
2021-06-18 |
2023-08-13 |
Not clear |
| Mariah A A Meyer, Max Anstötz, Lynn Y Ren, Michael P Fiske, Anita L Guedea, Viktoriya S Grayson, Samantha L Schroth, Ana Cicvaric, Katsuhiko Nishimori, Gianmaria Maccaferri, Jelena Radulovi. Stress-related memories disrupt sociability and associated patterning of hippocampal activity: a role of hilar oxytocin receptor-positive interneurons. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:33311459. |
we found that the encoding of stress-enhanced state-dependent memories robustly and sex specifically impairs sociability in male mice and disrupts the asymmetry of dentate gyrus (dg)/ca3 activity accompanying social interactions. |
2021-06-18 |
2023-08-13 |
mouse |
| Mark M Gergues, Christine N Yohn, Anusha Bharadia, Marjorie R Levinstein, Benjamin Adam Samuel. Dentate gyrus activin signaling mediates the antidepressant response. Translational psychiatry. vol 11. issue 1. 2021-06-18. PMID:33414389. |
we found several differences in expression of activin signaling-related genes between responders and non-responders in the dentate gyrus (dg), a region that is critical for the beneficial behavioral effects of fluoxetine. |
2021-06-18 |
2023-08-13 |
mouse |
| David P Herzog, Diego Pascual Cuadrado, Giulia Treccani, Tanja Jene, Verena Opitz, Annika Hasch, Beat Lutz, Klaus Lieb, Inge Sillaber, Michael A van der Kooij, Vijay K Tiwari, Marianne B Mülle. A distinct transcriptional signature of antidepressant response in hippocampal dentate gyrus granule cells. Translational psychiatry. vol 11. issue 1. 2021-06-18. PMID:33414410. |
we focused on the dentate gyrus (dg), a subregion of major interest in the context of antidepressant mechanisms. |
2021-06-18 |
2023-08-13 |
mouse |
| Farah Chamaa, Batoul Darwish, Ziad Nahas, Elie D Al-Chaer, Nayef E Saadé, Wassim Abou-Khei. Long-term stimulation of the anteromedial thalamus increases hippocampal neurogenesis and spatial reference memory in adult rats. Behavioural brain research. vol 402. 2021-06-18. PMID:33417991. |
previous work from our group showed that a single session of dbs to the anteromedial thalamic nucleus (amn) in awake rats, increased proliferation of stem/progenitor cells in the dentate gyrus (dg) of the hippocampus. |
2021-06-18 |
2023-08-13 |
rat |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
wistar rats (210-300 g) were injected with a single dose of pilocarpine hydrochloride (2.4 mg/2 µl) in the right lateral ventricle and video-monitored 24 h/d to detect spontaneous and recurrent seizures; microelectrodes were implanted in the dentate gyrus (dg) and ca3 and ca1 regions of these rats ipsilateral to the pilocarpine injection site 1 day after the first spontaneous seizure was observed, and only rats who suffered fr events were used in this work. |
2021-06-18 |
2023-08-13 |
rat |
| Alexander V Maltsev, Natalia V Bal, Pavel M Balaba. Serine/Threonine Phosphatases in LTP: Two B or Not to Be the Protein Synthesis Blocker-Induced Impairment of Early Phase. International journal of molecular sciences. vol 22. issue 9. 2021-06-15. PMID:34064311. |
direct measurement of the no production in hippocampal slices by the no-specific fluorescent probe daf-fm revealed that psbs strongly stimulate the no concentration in all studied brain areas: ca1, ca3, and dentate gyrus (dg). |
2021-06-15 |
2023-08-13 |
Not clear |
| Lucas B Comeras, Noa Hörmer, Pradeepa Mohan Bethuraj, Ramon O Tasa. NPY Released From GABA Neurons of the Dentate Gyrus Specially Reduces Contextual Fear Without Affecting Cued or Trace Fear. Frontiers in synaptic neuroscience. vol 13. 2021-06-15. PMID:34122036. |
here we investigated the role of npy in relation to gaba, both released from the same interneurons of the dorsal dentate gyrus (dg), in different aspects of fear conditioning. |
2021-06-15 |
2023-08-13 |
Not clear |
| Gislaine Olescowicz, Tuane B Sampaio, Cristine de Paula Nascimento-Castro, Patricia S Brocardo, Joana Gil-Mohapel, Ana Lúcia S Rodrigue. Protective Effects of Agmatine Against Corticosterone-Induced Impairment on Hippocampal mTOR Signaling and Cell Death. Neurotoxicity research. vol 38. issue 2. 2021-06-14. PMID:32399718. |
treatment on the levels of phosphorylated mtor (p-mtor), neuronal death, and overall volume in the hippocampal dentate gyrus (dg) of mice exposed to chronic corticosterone (20 mg/kg, p.o.) |
2021-06-14 |
2023-08-13 |
mouse |