| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jacopo Agrimi, Lucia Bernardele, Naeem Sbaiti, Marco Brondi, Donato D'Angelo, Marta Canato, Ivan Marchionni, Christian U Oeing, Giussy Barbara, Beatrice Vignoli, Marco Canossa, Nina Kaludercic, Gaya Spolverato, Anna Raffaello, Claudia Lodovichi, Marco Dal Maschio, Nazareno Paolocc. Reiterated male-to-female violence disrupts hippocampal estrogen receptor β expression, prompting anxiety-like behavior. iScience. vol 27. issue 9. 2024-09-04. PMID:39228787. |
rmfvi prompted anxiety-like behavior in female mice whose hippocampus displayed a marked neuronal loss and hampered neurogenesis, namely reduced brdu-dcx-positive nuclei and diminished dendritic arborization in the dentate gyrus (dg): effects paralleled by a substantial downregulation of the estrogen receptor β (erβ). |
2024-09-04 |
2024-09-06 |
mouse |
| Maltesh Kambali, Yan Li, Petr Unichenko, Jessica A Feria Pliego, Rachita Yadav, Jing Liu, Patrick McGuinness, Johanna G Cobb, Muxiao Wang, Rajasekar Nagarajan, Jinrui Lyu, Vanessa Vongsouthi, Colin J Jackson, Elif Engin, Joseph T Coyle, Jaeweon Shin, Nathaniel W Hodgson, Takao K Hensch, Michael E Talkowski, Gregg E Homanics, Vadim Y Bolshakov, Christian Henneberger, Uwe Rudolp. An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function. Molecular psychiatry. 2024-08-30. PMID:39210012. |
using a chromosome-engineered allelic series in mice, we report that a triplication of the gene encoding the glycine-catabolizing enzyme glycine decarboxylase (gldc) - as found on a small supernumerary marker chromosome in patients with psychosis - reduces extracellular glycine levels as determined by optical fluorescence resonance energy transfer (fret) in dentate gyrus (dg) and suppresses long-term potentiation (ltp) in mpp-dg synapses but not in ca3-ca1 synapses, reduces the activity of biochemical pathways implicated in schizophrenia and mitochondrial bioenergetics, and displays deficits in schizophrenia-like behaviors which are in part known to be dependent on the activity of the dentate gyrus, e.g., prepulse inhibition, startle habituation, latent inhibition, working memory, sociability and social preference. |
2024-08-30 |
2024-09-04 |
mouse |
| Reihaneh Mohammadkhani, Iraj Salehi, Samaneh Safari, Reza Ghahremani, Alireza Komaki, Seyed Asaad Karim. Continuous exercise training rescues hippocampal long-term potentiation in the VPA rat model of Autism: Uncovering sex-specific effects. Neuroscience. 2024-08-30. PMID:39214164. |
the aim of the present study was to investigate the effects of interval training (it) and continuous training (ct) exercises on ltp in the hippocampal dentate gyrus (dg) neurons of valproic acid (vpa) rat model of autism. |
2024-08-30 |
2024-09-04 |
rat |
| Krista A Mitchnick, Sabrina Labardo, R Shayna Rosenbau. Dissociations in perceptual discrimination following selective damage to the dentate gyrus versus CA1 subfield of the hippocampus. Cortex; a journal devoted to the study of the nervous system and behavior. vol 179. 2024-08-28. PMID:39197409. |
the current study examined the nature and extent of a double dissociation between the dentate gyrus (dg) to discrimination processes and ca1 subfield to retention/retrieval by testing two unique individuals with bilateral damage to the dg (case bl) and ca1 (case br). |
2024-08-28 |
2024-09-01 |
Not clear |
| Krista A Mitchnick, Sabrina Labardo, R Shayna Rosenbau. Dissociations in perceptual discrimination following selective damage to the dentate gyrus versus CA1 subfield of the hippocampus. Cortex; a journal devoted to the study of the nervous system and behavior. vol 179. 2024-08-28. PMID:39197409. |
separate research has demonstrated separable contributions of hpc subregions to component memory processes, with the dentate gyrus (dg) required for mnemonic discrimination of similar inputs and the ca1 subfield required for retention and retrieval, but contributions of these subregions to perceptual processes is understudied. |
2024-08-28 |
2024-09-01 |
Not clear |
| Shenjia Gao, Ruling Shen, Jie Li, Yi Jiang, Hao Sun, Xinyi Wu, Xiya Li, Changhong Miao, Miao He, Jun Wang, Wankun Che. N-acetyltransferase 10 mediates cognitive dysfunction through the acetylation of GABA Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 36. 2024-08-27. PMID:39190359. |
our findings demonstrate that clp significantly upregulates nat10 expression and mrna acetylation in the excitatory neurons of the hippocampal dentate gyrus (dg). |
2024-08-27 |
2024-08-30 |
mouse |
| Jonas Fritze, Stefan Lang, Mikael Sommarin, Shamit Soneji, Henrik Ahleniu. Single-cell RNA sequencing of aging neural progenitors reveals loss of excitatory neuron potential and a population with transcriptional immune response. Frontiers in neuroscience. vol 18. 2024-08-26. PMID:39184324. |
in the adult murine brain, neural stem cells (nscs) can be found in two main niches: the dentate gyrus (dg) and the subventricular zone (svz). |
2024-08-26 |
2024-08-28 |
Not clear |
| Zhengshan Liu, Yu H Sun, Yue Ren, Jessica Marie Perez, Daniel Scott, Carol Tamming. Upregulated solute-carrier family genes in the hippocampus of schizophrenia can be rescued by antipsychotic medications. Schizophrenia research. vol 272. 2024-08-25. PMID:39182310. |
our previous studies have found that functional changes in the hippocampal circuit from dentate gyrus (dg) to cornu ammonis 3 and 1 (ca3, ca1) are highly associated with schizophrenia (sz). |
2024-08-25 |
2024-08-28 |
human |
| Keisuke Otsubo, Naoko Sakashita, Yuki Nishimoto, Yo Sato, Takehisa Tsutsui, Katsunori Kobayashi, Kanzo Suzuki, Eri Segi-Nishid. Role of desmoplakin in supporting neuronal activity, neurogenic processes, and emotional-related behaviors in the dentate gyrus. Frontiers in neuroscience. vol 18. 2024-08-23. PMID:39176381. |
dsp is specifically expressed in the hippocampal dentate gyrus (dg) in the central nervous system. |
2024-08-23 |
2024-08-25 |
mouse |
| Shunya Yagi, Ahmad Mohammad, Yanhua Wen, Ariel A Batallán Burrowes, Samantha A Blankers, Liisa A M Gale. Estrogens dynamically regulate neurogenesis in the dentate gyrus of adult female rats. Hippocampus. 2024-08-21. PMID:39166359. |
the present study assessed the effects of estrone and estradiol on the maturation timeline of neurogenesis in the dentate gyrus (dg) of ovariectomized (a model of surgical menopause) young adult sprague-dawley rats using daily subcutaneous injections of 17β-estradiol, estrone or vehicle. |
2024-08-21 |
2024-08-23 |
rat |
| Ming Li, Fang Yang, Xiaoling Zhang, Hong Yang, Xingjin He, Zhongnan Mao, Liya Ma. Electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting TLR4/NF-κB/NLRP3 signaling pathway. Neuroreport. 2024-08-21. PMID:39166408. |
the number of granulosa cells and doublecortin-positive cells in the dentate gyrus (dg) were significantly decreased in psd group, which were significantly upregulated (p < 0.01) by electroacupuncture. |
2024-08-21 |
2024-08-23 |
mouse |
| Marie H Sabec, Quentin R Savage, John L Wood, Uwe Masko. Targeting high-affinity nicotinic receptors protects against the functional consequences of β-amyloid in mouse hippocampus. Molecular psychiatry. 2024-08-20. PMID:39164528. |
the hippocampus is affected early in the pathogenesis of ad, however the impact of soluble β-amyloid on the dentate gyrus (dg) subregion of the hippocampus and its interaction with nicotinic acetylcholine receptors (nachrs) within this region are not known. |
2024-08-20 |
2024-08-23 |
mouse |
| Maria Florencia Rossetti, Rocio Schumacher, Guillermina Canesini, Pamela Fernandez, Luisa Gaydou, Cora Stoker, Jorge Guillermo Ramo. Neonatal overfeeding promotes anxiety, impairs episodic-like memory, and disrupts transcriptional regulation of hippocampal steroidogenic enzymes. The Journal of nutritional biochemistry. 2024-08-18. PMID:39154791. |
utilizing micropunch techniques, dentate gyrus (dg), ca1, and ca3 regions were extracted for analysis of mrna expression and methylation patterns. |
2024-08-18 |
2024-08-21 |
human |
| Claudius E Degro, Imre Vida, Sam A Booke. Postsynaptic GABA Hippocampus. 2024-08-14. PMID:39138952. |
postsynaptic gaba the processing of rich synaptic information in the dentate gyrus (dg) relies on a diverse population of inhibitory gabaergic interneurons to regulate cellular and circuit activity, in a layer-specific manner. |
2024-08-14 |
2024-08-16 |
Not clear |
| Pasquale Esposito, Eleni Dubé-Zinatelli, Michelle Gandelman, Ella Liu, Luna Cappelletti, Jacky Liang, Nafissa Ismai. The Enduring Effects of Antimicrobials and Lipopolysaccharide on the Cellular Mechanisms and Behaviours Associated with Neurodegeneration in Pubertal Male and Female CD1 Mice. Neuroscience. 2024-08-10. PMID:39127344. |
males treated with amns alone had decreased sigma-1 receptor (s1r) expression in the cornu ammonis 1 (ca1) and dentate gyrus (dg), while females treated with both amns and lps had decreased s1r expression. |
2024-08-10 |
2024-08-13 |
mouse |
| Rui Wang, Linzhong Zhang, Xia Wang, Wen Li, Tingliang Jian, Pengcheng Yin, Xinzhi Wang, Qianwei Chen, Xiaowei Chen, Han Qi. Electrophysiological activity pattern of mouse hippocampal CA1 and dentate gyrus under isoflurane anesthesia. Frontiers in cellular neuroscience. vol 18. 2024-08-06. PMID:39104439. |
the ca1 and dentate gyrus (dg), serving as the primary efferent and gateway of the hippocampal trisynaptic circuit facilitating cognitive learning and memory functions, exhibit significant differences in cellular composition, molecular makeup, and responses to various stimuli. |
2024-08-06 |
2024-08-08 |
mouse |
| Sang-Yoon Kim, Woochang Li. Effect of adult-born immature granule cells on pattern separation in the hippocampal dentate gyrus. Cognitive neurodynamics. vol 18. issue 4. 2024-08-06. PMID:39104672. |
young immature granule cells (imgcs) appear via adult neurogenesis in the hippocampal dentate gyrus (dg). |
2024-08-06 |
2024-08-08 |
Not clear |
| Yin Xia, Min Xie, Ran Zhang, Lingchao Kong, Lamei Yao, Lesha Zhang, Yuanhai L. Effects of dexmedetomidine on depression-like behaviour in chronic restraint stress mice: Involvement of specific brain regions. Biochemical and biophysical research communications. vol 734. 2024-08-01. PMID:39088982. |
other brain regions, including the dentate gyrus (dg), pyriform cortex (pir), anterior part of paraventricular thalamic nucleus (pva), arcuate nucleus (arc), and core or shell of accumbens nucleus (acbc or acbs), presented differences in c-fos expression. |
2024-08-01 |
2024-08-05 |
mouse |
| Thomas C Watson, Sam A Booke. Somatostatin interneurons recruit pre- and postsynaptic GABA eNeuro. 2024-07-31. PMID:39084907. |
somatostatin interneurons recruit pre- and postsynaptic gaba the integration of spatial information in the mammalian dentate gyrus (dg) is critical to navigation. |
2024-07-31 |
2024-08-03 |
Not clear |
| Peng Yu, Miao Cheng, Na Wang, Chendong Wu, Keju Qian. Pubertal maternal presence reduces anxiety and increases adult neurogenesis in Kunming mice offspring. Pharmacology, biochemistry, and behavior. 2024-07-30. PMID:39079561. |
the social interaction and anxiety behaviors, as well as the expression of oxytocin (ot) in the paraventricular nucleus (pvn) and supraoptic nucleus (son), and the number of new generated neurons and the expression of estrogen receptor alpha (erα) in the dentate gyrus (dg) were assessed. |
2024-07-30 |
2024-08-02 |
mouse |