Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xiguang Xu, Yu Lin, Liduo Yin, Priscila da Silva Serpa, Benjamin Conacher, Christina Pacholac, Francisco Carvallo, Terry Hrubec, Shannon Farris, Kurt Zimmerman, Xiaobin Wang, Hehuang Xi. Spatial Transcriptomics and Single-Nucleus Multi-omics Analysis Revealing the Impact of High Maternal Folic Acid Supplementation on Offspring Brain Development. bioRxiv : the preprint server for biology. 2024-07-29. PMID:39071367. |
single-nucleus multi-omics analysis revealed that maturing excitatory neurons in the dentate gyrus (dg) are particularly vulnerable to high maternal fa intake, leading to aberrant gene expressions and chromatin accessibility in pathways governing ribosomal biogenesis critical for synaptic formation. |
2024-07-29 |
2024-08-02 |
mouse |
Qing Shang, Lizhi Zhang, Biao Xiao, Jianhong Yang, Jie Sun, Xiang Gao, Yi Huang, Zhengchun Wan. Juvenile Bright Light Exposure Ameliorates Adult Behavioral Abnormalities by Enhancing Neurogenesis in a N-methyl-D-aspartate Receptor Dysfunction Mouse Model Relevant for Cognitive Impairment in Schizophrenia. Behavioural brain research. 2024-07-24. PMID:39047873. |
following three weeks of juvenile bright light exposure (5-8 weeks old), significant increases in proliferating neurons (brdu+) and immature neurons (dcx+ cells) were observed in the dentate gyrus (dg) and lateral ventricle of mk-801-treated mice. |
2024-07-24 |
2024-07-28 |
mouse |
Minghua Li, Yu-Qiu Jiang, Daniel K Lee, Haoran Wang, Melissa C Lu, Qian Su. Dorsoventral heterogeneity of synaptic connectivity in hippocampal CA3 pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-07-18. PMID:39025678. |
ca3 pyramidal neurons (pns) receive two prominent excitatory inputs - mossy fibers (mfs) from dentate gyrus (dg) and recurrent collaterals (rcs) from ca3 pns - that play opposing roles in pattern separation and pattern completion, respectively. |
2024-07-18 |
2024-07-21 |
mouse |
Shu Xiao, Zibin Yang, Hong Yan, Guanmao Chen, Shuming Zhong, Pan Chen, Hui Zhong, Hengwen Yang, Yanbin Jia, Zhinan Yin, Jiaying Gong, Li Huang, Ying Wan. Gut proinflammatory bacteria is associated with abnormal functional connectivity of hippocampus in unmedicated patients with major depressive disorder. Translational psychiatry. vol 14. issue 1. 2024-07-16. PMID:39013880. |
severn pairs of hippocampus subregions (the bilateral cornu ammonis [ca1-ca3], dentate gyrus (dg), entorhinal cortex, hippocampal-amygdaloid transition area, and subiculum) were selected as the seeds in the functional connectivity (fc) analysis. |
2024-07-16 |
2024-07-19 |
human |
Wei-Li Chang, Rene He. Adult Neurogenesis, Context Encoding, and Pattern Separation: A Pathway for Treating Overgeneralization. Advances in neurobiology. vol 38. 2024-07-15. PMID:39008016. |
the integration of these new neurons into the dentate gyrus (dg) has implications for memory encoding, with unique firing and wiring properties of immature neurons that affect how the hippocampal network encodes and stores attributes of memory. |
2024-07-15 |
2024-07-18 |
Not clear |
Lizhi Zhang, Yiying Zhou, Yanhong Xie, Yudong Ying, Yan Li, Sen Ye, Zhengchun Wan. Adjunctive clozapine with bright light mitigates cognitive deficits by synaptic plasticity and neurogenesis in sub-chronic MK-801 treated mice. Pharmacology, biochemistry, and behavior. 2024-07-13. PMID:39002805. |
additionally, brdu labeling revealed that clz + lt further enhances neurogenesis in the dentate gyrus (dg) and lateral ventricle (lv) of sub-chronic mk-801 treated mice. |
2024-07-13 |
2024-07-16 |
mouse |
Xinyu Zou, Qian Tang, Ryota Ojiro, Shunsuke Ozawa, Momoka Shobudani, Yuri Sakamaki, Yuri Ebizuka, Meilan Jin, Toshinori Yoshida, Makoto Shibutan. Increased spontaneous activity and progressive suppression of adult neurogenesis in the hippocampus of rat offspring after maternal exposure to imidacloprid. Chemico-biological interactions. 2024-07-13. PMID:39002876. |
the present study investigated the effects of maternal exposure to imi on behaviors and adult neurogenesis in the hippocampal dentate gyrus (dg) of rat offspring. |
2024-07-13 |
2024-07-16 |
rat |
Frederike Schäfer, Archana Tomar, Shogo Sato, Raffaele Teperino, Axel Imhof, Shibojyoti Lahir. Enhanced in situ spatial proteomics by effective combination of MALDI imaging and LC-MS/MS. Molecular & cellular proteomics : MCP. 2024-07-12. PMID:38996918. |
as an example, we identified the groups of proteins distinguishing the neuronal populations of dentate gyrus (dg) and the cornu ammonis (ca) in the same brain section. |
2024-07-12 |
2024-07-15 |
mouse |
Mariane de Araújo E Silva, Fernando da Silva Fiorin, Rodrigo Marques de Melo Santiago, Abner Cardoso Rodrigue. Brain connectivity analysis in preictal phases of seizure induced by pentylenetetrazol in rats. Brain research. 2024-07-10. PMID:38986828. |
to investigate brain connectivity in male wistar rats during the preictal phase of ptz-induced seizures (60 mg/kg), we recorded local field potentials in the primary motor (m1) cortex, the ventral anterior (va) nucleus of the thalamus, the hippocampal ca1 area, and the dentate gyrus (dg) during the baseline period and after ptz administration. |
2024-07-10 |
2024-07-13 |
rat |
Ting Zhao, Yan Hong, Bowen Yan, Suming Huang, Guo-Li Ming, Hongjun Son. Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a. Nature communications. vol 15. issue 1. 2024-07-06. PMID:38971831. |
quiescence, a hallmark of adult neural stem cells (nscs), is required for maintaining the nsc pool to support life-long continuous neurogenesis in the adult dentate gyrus (dg). |
2024-07-06 |
2024-07-11 |
mouse |
Zhuo-Hang Zhang, Bo Wang, Yan Peng, Ya-Wei Xu, Chang-Hong Li, Ya-Lei Ning, Yan Zhao, Fa-Bo Shan, Bo Zhang, Nan Yang, Jing Zhang, Xing Chen, Ren-Ping Xiong, Yuan-Guo Zhou, Ping L. Identification of a Hippocampus-to-Zona Incerta Projection involved in Motor Learning. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024-07-03. PMID:38958448. |
using recombinant adeno-associated virus, the projections to the zi are surprisingly identified as originating from the dorsal dentate gyrus (dg) and ca1 subregions of the dhpc. |
2024-07-03 |
2024-07-06 |
Not clear |
Pablo Bonilla, Alexandria Shanks, Yatin Nerella, Alessandra Porc. Effects of chronic light cycle disruption during adolescence on circadian clock, neuronal activity rhythms, and behavior in mice. Frontiers in neuroscience. vol 18. 2024-07-02. PMID:38952923. |
clock gene expression and neuronal activity rhythms analysis revealed that lcd disrupted local molecular clock and neuronal activity in the dentate gyrus (dg) and in the medial amygdala (mea) but not in the circadian pacemaker (scn). |
2024-07-02 |
2024-07-04 |
mouse |
Satoshi Deyama, Masabumi Minami, Katsuyuki Kaned. [Resolvin E1 as a potential lead for the treatment of depression]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 159. issue 4. 2024-06-30. PMID:38945902. |
local infusion of rve1 into the medial prefrontal cortex (mpfc) or dorsal hippocampal dentate gyrus (dg) also produces antidepressant-like effects, suggesting that these brain regions are sites of action of rve1. |
2024-06-30 |
2024-07-03 |
mouse |
Mengwen Sun, Weizhen Xue, Hu Meng, Xiaoxuan Sun, Tianlan Lu, Weihua Yue, Lifang Wang, Dai Zhang, Jun L. Dentate Gyrus Morphogenesis is Regulated by an Autism Risk Gene Trio Function in Granule Cells. Neuroscience bulletin. 2024-06-22. PMID:38907786. |
here, we report that deletion of trio, a high-susceptibility gene of asds, causes a postnatal dentate gyrus (dg) hypoplasia with a zigzagged suprapyramidal blade, and the trio-deficient mice display autism-like behaviors. |
2024-06-22 |
2024-06-25 |
mouse |
Elissavet Chartampila, Karim S Elayouby, Paige Leary, John J LaFrancois, David Alcantara-Gonzalez, Swati Jain, Kasey Gerencer, Justin J Botterill, Stephen D Ginsberg, Helen E Scharfma. Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease. eLife. vol 12. 2024-06-21. PMID:38904658. |
in mouse models, hyperexcitability is also reflected by elevated expression of the transcription factor ∆fosb in the granule cells (gcs) of the dentate gyrus (dg), which are the principal cell type. |
2024-06-21 |
2024-06-23 |
mouse |
Jeniffer Sanguino-Gómez, Stefan Huijgens, Maxine den Hartog, Inim J M Schenk, Wenya Kluck, Tamara D Versluis, Harm J Kruger. Neural correlates of learning and memory are altered by early-life stress. Neurobiology of learning and memory. 2024-06-21. PMID:38906243. |
this study examined in male mice whether early life stress (els) alters memory and brain activation patterns, by studying the expression of the immediate early genes (iegs) c-fos and arc in the dentate gyrus (dg) and basolateral amygdala (bla) after training and memory retrieval in a fear conditioning task. |
2024-06-21 |
2024-06-24 |
mouse |
Alexandra Gros, Fandilla Marie Furlan, Vanessa Rouglan, Alexandre Favereaux, Bruno Bontempi, Jean-Luc More. Physical exercise restores adult neurogenesis deficits induced by simulated microgravity. NPJ microgravity. vol 10. issue 1. 2024-06-21. PMID:38906877. |
we studied the proliferation, survival and maturation of newborn cells in the following neurogenic niches: the subventricular zone (svz)/olfactory bulb (ob) and the dentate gyrus (dg) of the hippocampus, at different delays following various periods of smg. |
2024-06-21 |
2024-06-24 |
rat |
Ivette Espinoza, Francisco Cabrera, Julio César Morales-Medina, Ma de Jesús Gómez-Villalobos, Gonzalo Flore. The administration of Cerebrolysin elicits neuroprotective and neurorepair effects in an animal model of type 1 diabetes mellitus. Behavioural brain research. 2024-06-19. PMID:38897418. |
this research aims to investigate the neuroprotective and neurorepair effect of cbl on the cytoarchitecture of neurons and spine density in pyramidal neurons of the prefrontal (pfc) and the ca1 region of the dorsal hippocampus, as well as spheroidal neurons of the dentate gyrus (dg), in stz-induced dm. |
2024-06-19 |
2024-06-22 |
rat |
Yangyang Ge, Xiaoke Dou, Pu Chen, Jiayi Chen, Maosha Dai, Shanglong Yao, Yun Li. Treadmill Exercise Enhances Post-Stroke Functional Recovery in Mice via the CX3CL1/CX3CR1 Signaling Pathway. Molecular neurobiology. 2024-06-17. PMID:38886327. |
western blot detected cx3cl1 and cx3cr1 protein expression, while immunofluorescence observed these proteins, neurogenesis in the subventricular zone (svz), rostral migratory stream (rms), and dentate gyrus (dg), along with iba1 and cd68 co-expression. |
2024-06-17 |
2024-06-21 |
mouse |
Alfredo Zuniga, Jiawei Han, Isaac Miller-Crews, Laura A Agee, Hans A Hofmann, Michael R Dre. Extinction training suppresses activity of fear memory ensembles across the hippocampus and alters transcriptomes of fear-encoding cells. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-06-14. PMID:38877180. |
contextual fear conditioning has been shown to activate a set of "fear ensemble" cells in the hippocampal dentate gyrus (dg) whose reactivation is necessary and sufficient for expression of contextual fear. |
2024-06-14 |
2024-06-17 |
Not clear |