| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wen-Jing Ning, Ren-Jun Lv, Ning Xu, Xun-Yao Hou, Chao Shen, Yun-Liang Guo, Zhong-Yu Fan, Na Cao, Xue-Ping Li. Lycopene-Loaded Microemulsion Regulates Neurogenesis in Rats with A Neural plasticity. vol 2021. 2021-10-08. PMID:34545285. |
lycopene-loaded microemulsion regulates neurogenesis in rats with a to investigate the effects of lycopene-loaded microemulsion (lme) on the cognitive function and neurogenesis in the dentate gyrus (dg) of the hippocampus and subventricular (svz) region of rats with amyloid |
2021-10-08 |
2023-08-13 |
rat |
| Mariah A A Meyer, Jelena Radulovi. Functional differentiation in the transverse plane of the hippocampus: An update on activity segregation within the DG and CA3 subfields. Brain research bulletin. vol 171. 2021-10-07. PMID:33727088. |
more recent findings, however, demonstrate that functional segregation also occurs along transverse axis of the hippocampus, within the hippocampal subfields ca1, ca2, ca3, and the dentate gyrus (dg). |
2021-10-07 |
2023-08-13 |
Not clear |
| Xinxin Xu, Shitong Xiang, Qiyue Zhang, Tao Yin, Wanzeng Kong, Tao Zhan. rTMS alleviates cognitive and neural oscillatory deficits induced by hindlimb unloading in mice via maintaining balance between glutamatergic and GABAergic systems. Brain research bulletin. vol 172. 2021-10-07. PMID:33895272. |
our data show that rtms can significantly alleviate behavior deficits, modulate theta oscillation, improve the disturbed power distribution of theta oscillation and the decreased strength of cross-frequency coupling in the dentate gyrus region, and effectively mitigated the blocked communication of neural information in the perforant pathway (pp)-dentate gyrus (dg) neural pathway in hu mice. |
2021-10-07 |
2023-08-13 |
mouse |
| Wakana Sakuma, Osamu Nakagawasai, Wataru Nemoto, Takayo Odaira, Takumi Ogawa, Kiminori Ohta, Yasuyuki Endo, Koichi Tan-N. Antidepressant effect of BE360, a new selective estrogen receptor modulator, activated via CREB/BDNF, Bcl-2 signaling pathways in ovariectomized mice. Behavioural brain research. vol 393. 2021-10-04. PMID:32535181. |
neurogenesis in the hippocampal dentate gyrus (dg) was measured by analyzing cells expressing doublecortin (dcx) following 5-bromo-2'-deoxyuridine (brdu) uptake. |
2021-10-04 |
2023-08-13 |
mouse |
| Majid Motaghinejad, Roya Mashayekh, Manijeh Motevalian, Sepideh Safar. The possible role of CREB-BDNF signaling pathway in neuroprotective effects of minocycline against alcohol-induced neurodegeneration: molecular and behavioral evidences. Fundamental & clinical pharmacology. vol 35. issue 1. 2021-10-04. PMID:32579730. |
in comparison, minocycline attenuated alcohol-induced neurodegeneration; elevating expression levels of p-creb and bdnf and inhibited alcohol induced histopathological changes in both dentate gyrus (dg) and ca1 of hippocampus. |
2021-10-04 |
2023-08-13 |
human |
| Mohammadmehdi Hadipour, Gholam Hossein Meftahi, Mohammad Reza Afarinesh, Gila Pirzad Jahromi, Boshra Hate. Crocin attenuates the granular cells damages on the dentate gyrus and pyramidal neurons in the CA3 regions of the hippocampus and frontal cortex in the rat model of Alzheimer's disease. Journal of chemical neuroanatomy. vol 113. 2021-10-01. PMID:32534024. |
hence, we investigated the efficacy of crocin in the ca3 and dentate gyrus (dg) regions of the hippocampus and also in frontal cortex neurons employing a rat model of ad. |
2021-10-01 |
2023-08-13 |
rat |
| Stephanie Veerasammy, Juliette Van Steenwinckel, Tifenn Le Charpentier, Joon Ho Seo, Bobbi Fleiss, Pierre Gressens, Steven W Leviso. Perinatal IL-1β-induced inflammation suppresses Tbr2 Brain, behavior, & immunity - health. vol 7. 2021-10-01. PMID:34589867. |
these deficits are accompanied by decreased neurogenesis and proliferation in the subgranular zone (sgz) of the dentate gyrus (dg) of the hippocampus. |
2021-10-01 |
2023-08-13 |
mouse |
| Lizbeth García-Velázquez, Clorinda Aria. Differential Regulation of Wnt Signaling Components During Hippocampal Reorganization After Entorhinal Cortex Lesion. Cellular and molecular neurobiology. vol 41. issue 3. 2021-09-30. PMID:32435957. |
in this work, we assessed the reorganization process of the dentate gyrus (dg) at 1, 3, 7, and 30 days after an excitotoxic lesion in layer ii of the entorhinal cortex. |
2021-09-30 |
2023-08-13 |
Not clear |
| Yu-Ting Wei, Jei-Wei Wu, Chia-Wei Yeh, Hung-Chang Shen, Kun-Pin Wu, Imre Vida, Cheng-Chang Lie. Morpho-physiological properties and connectivity of vasoactive intestinal polypeptide-expressing interneurons in the mouse hippocampal dentate gyrus. The Journal of comparative neurology. vol 529. issue 10. 2021-09-30. PMID:33484471. |
among the hippocampal subregions, the dentate gyrus (dg) is the first station that receives multimodal sensory information from the cortex. |
2021-09-30 |
2023-08-13 |
mouse |
| Zuotian Wu, Gaohua Wang, Ling Xiao, Yanyan Wei, Huiling Wang, Lin Zhou, Limin Su. Resilience in the LPS-induced acute depressive-like behaviors: Increase of CRMP2 neuroprotection and microtubule dynamics in hippocampus. Brain research bulletin. vol 162. 2021-09-29. PMID:32645362. |
in addition, the expression of crmp2 and alpha-tubulin in dentate gyrus (dg) region increased in resilient animals, but not in ca1 and ca3 regions. |
2021-09-29 |
2023-08-13 |
rat |
| Yihua He, Yuqin Peng, Yuan Chang, Juan Zhu, Zheqi Li, Kaibin Huang, Suyue Pa. Utilizing the Faxitron MultiRad 225 X-ray irradiation system for the construction of mouse chronic whole brain radiation model. Journal of radiation research. 2021-09-29. PMID:34585253. |
however, two months later, the results of immunofluorescence showed that astrocytes and microglia were activated continuously, and the number of immature neurons in dentate gyrus (dg) area of hippocampus was significantly reduced, in accordance with the features of chronic pathophysiological changes. |
2021-09-29 |
2023-08-13 |
mouse |
| Francesca Billwiller, Laura Castillo, Heba Elseedy, Anton Ivanovich Ivanov, Jennyfer Scapula, Antoine Ghestem, Julien Carponcy, Paul Antoine Libourel, Hélène Bras, Nabila ElSayed Abdelmeguid, Esther Krook-Magnuson, Ivan Soltesz, Christophe Bernard, Pierre-Hervé Luppi, Monique Esclape. GABA-glutamate supramammillary neurons control theta and gamma oscillations in the dentate gyrus during paradoxical (REM) sleep. Brain structure & function. vol 225. issue 9. 2021-09-28. PMID:32970253. |
several studies suggest that neurons from the lateral region of the sum (suml) innervating the dorsal dentate gyrus (dg) display a dual gabaergic and glutamatergic transmission and are specifically activated during paradoxical (rem) sleep (ps). |
2021-09-28 |
2023-08-13 |
mouse |
| Priscila B Rosa, Luis E B Bettio, Vivian B Neis, Morgana Moretti, Fernanda N Kaufmann, Mauren K Tavares, Isabel Werle, Yasmim Dalsenter, Nicolle Platt, Axel F Rosado, Daiane B Fraga, Isabella A Heinrich, Andiara E Freitas, Rodrigo B Leal, Ana Lúcia S Rodrigue. Antidepressant-like effect of guanosine involves activation of AMPA receptor and BDNF/TrkB signaling. Purinergic signalling. vol 17. issue 2. 2021-09-28. PMID:33712981. |
finally, guanosine was effective in the nsf test (after 1 h) but caused no alterations in dendritic spine density and remodeling in the ventral dentate gyrus (dg). |
2021-09-28 |
2023-08-13 |
mouse |
| Felix Beyer, Wichard Lüdje, Julian Karpf, Gesine Saher, Ruth Beckervordersandfort. Distribution of Aldh1L1-CreER Frontiers in neuroscience. vol 15. 2021-09-25. PMID:34557065. |
distribution of aldh1l1-creer in the adult central nervous system, neural stem cells (nscs) reside in two discrete niches: the subependymal zone (sez) of the lateral ventricle and the subgranular zone (sgz) of the dentate gyrus (dg). |
2021-09-25 |
2023-08-13 |
Not clear |
| Kirsten Hülskötter, Fred Lühder, Alexander Flügel, Vanessa Herder, Wolfgang Baumgärtne. Tamoxifen Application Is Associated with Transiently Increased Loss of Hippocampal Neurons following Virus Infection. International journal of molecular sciences. vol 22. issue 16. 2021-09-24. PMID:34445189. |
applied at 0, 2 and 4 dpi, tamoxifen had a negative impact on the number of doublecortin (dcx)-positive cells within the dentate gyrus (dg) at 14 dpi, without a long-lasting effect on neuronal loss at 147 dpi. |
2021-09-24 |
2023-08-13 |
mouse |
| Eduardo Domínguez-Rivas, Evangelina Ávila-Muñoz, Stephan W Schwarzacher, Angélica Zeped. Adult hippocampal neurogenesis in the context of lipopolysaccharide-induced neuroinflammation: A molecular, cellular and behavioral review. Brain, behavior, and immunity. vol 97. 2021-09-22. PMID:34174334. |
one of these areas is the subgranular zone of the dentate gyrus (dg) in the hippocampus. |
2021-09-22 |
2023-08-13 |
Not clear |
| Gabriel Berdugo-Vega, Chi-Chieh Lee, Alexander Garthe, Gerd Kempermann, Federico Calegar. Adult-born neurons promote cognitive flexibility by improving memory precision and indexing. Hippocampus. vol 31. issue 10. 2021-09-21. PMID:34174010. |
adult neurogenesis in the hippocampal dentate gyrus (dg) is an extraordinary form of plasticity fundamental for cognitive flexibility. |
2021-09-21 |
2023-08-13 |
Not clear |
| Boris Brant, Tchelet Stern, Huda Adwan Shekhidem, Liron Mizrahi, Idan Rosh, Yam Stern, Polina Ofer, Ayat Asleh, George K Essien Umanah, Reem Jada, Nina S Levy, Andrew P Levy, Shani Ster. IQSEC2 mutation associated with epilepsy, intellectual disability, and autism results in hyperexcitability of patient-derived neurons and deficient synaptic transmission. Molecular psychiatry. 2021-09-18. PMID:34535765. |
we showed that immature iqsec2 mutant dentate gyrus (dg) granule neurons were extremely hyperexcitable, exhibiting increased sodium and potassium currents compared to those of crispr-cas9-corrected isogenic controls, and displayed dysregulation of genes involved in differentiation and development. |
2021-09-18 |
2023-08-13 |
human |
| Malgorzata Lopatynska-Mazurek, Anna Pankowska, Ewa Gibula-Tarlowska, Radoslaw Pietura, Jolanta H Kotlinsk. Rapamycin Improves Recognition Memory and Normalizes Amino-Acids and Amines Levels in the Hippocampal Dentate Gyrus in Adult Rats Exposed to Ethanol during the Neonatal Period. Biomolecules. vol 11. issue 3. 2021-09-15. PMID:33673489. |
moreover, the effects of rapamycin pre-treatment during neonatal ethanol exposure on the content of amino-acids and amines essential for the proper development of cognitive function in the dentate gyrus (dg) of the hippocampus was evaluated using proton magnetic resonance spectroscopy (1h mrs) in male adult (pnd 60) rats. |
2021-09-15 |
2023-08-13 |
human |
| Yoshihide Sehara, Yuka Hayashi, Kenji Ohba, Ryosuke Uchibori, Masashi Urabe, Ayumu Inutsuka, Kuniko Shimazaki, Kensuke Kawai, Hiroaki Mizukam. Higher Transduction Efficiency of AAV5 to Neural Stem Cells and Immature Neurons in Gerbil Dentate Gyrus Compared to AAV2 and rh10. Human gene therapy. 2021-09-15. PMID:34348481. |
however, the precise tropism of aavs in the dentate gyrus (dg), the region where persistent neurogenesis occurs in the adult brain, is not fully understood. |
2021-09-15 |
2023-08-13 |
Not clear |