| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shinichiro Ochi, Keisuke Sekiya, Naoki Abe, Yu Funahashi, Hiroshi Kumon, Yuta Yoshino, Tasuku Nishihara, Shuken Boku, Jun-Ichi Iga, Shu-Ichi Uen. Neural precursor cells are decreased in the hippocampus of the delayed carbon monoxide encephalopathy rat model. Scientific reports. vol 11. issue 1. 2021-10-27. PMID:33737717. |
in this study, the effects of co exposure on the dentate gyrus (dg) were investigated in a wistar rat model by histochemical and molecular methods. |
2021-10-27 |
2023-08-13 |
rat |
| Mola Mohammadi, Homa Manaheji, Nader Maghsoudi, Samira Danyali, Mansoureh Baniasadi, Jalal Zaringhala. Microglia dependent BDNF and proBDNF can impair spatial memory performance during persistent inflammatory pain. Behavioural brain research. vol 390. 2021-10-25. PMID:32442548. |
studying the cellular changes showed that persistent inflammatory pain increased the microglial activity in ca1 and dentate gyrus (dg) regions. |
2021-10-25 |
2023-08-13 |
rat |
| Samir A Nacer, Ayland C Letsinger, Simone Otto, Jemma Strauss DeFilipp, Viktoriya D Nikolova, Natallia V Riddick, Korey D Stevanovic, Jesse D Cushman, Jerrel L Yake. Loss of α7 nicotinic acetylcholine receptors in GABAergic neurons causes sex-dependent decreases in radial glia-like cell quantity and impairments in cognitive and social behavior. Brain structure & function. vol 226. issue 2. 2021-10-25. PMID:33398432. |
the dentate gyrus (dg) is a unique brain structure in that neurons can be generated postnatally and integrated within existing circuitry throughout life. the maturation process of these newly generated neurons (granule cells) is modulated by nicotinic acetylcholine receptors (nachrs) through a variety of mechanisms such as neural stem pool proliferation, cell survival, signal modulation, and dendritic integration. |
2021-10-25 |
2023-08-13 |
mouse |
| Bolanle Fatimat Olabiyi, Catherine Fleitas, Bahira Zammou, Isidro Ferrer, Claire Rampon, Joaquim Egea, Carme Espine. proNGF Involvement in the Adult Neurogenesis Dysfunction in Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 19. 2021-10-25. PMID:34639085. |
interestingly, work with rodents has shown that adult neurogenesis in the dentate gyrus (dg) of the hippocampus is vital for some cognitive aspects, as increasing neurogenesis improves memory, while its disruption triggers the opposite effect. |
2021-10-25 |
2023-08-13 |
mouse |
| Laura García-Durán, Antonio Flores-Burgess, Noelia Cantero-García, Araceli Puigcerver, José Ángel Narváez, Kjell Fuxe, Luis Santín, Carmelo Millón, Zaida Díaz-Cabial. Galanin(1-15) Potentiates the Antidepressant-like Effects Induced by Escitalopram in a Rat Model of Depression. International journal of molecular sciences. vol 22. issue 19. 2021-10-25. PMID:34639188. |
our immunohistochemistry and principal component analysis (pca) analysis suggest that two functional networks are involved in these effects; one includes the lateral (lhb) and medial (mhb) habenula, dorsal raphe (dr) and ventral tegmental area (vta), and the other consists of the dentate gyrus (dg), and prefrontal cortex (pfc). |
2021-10-25 |
2023-08-13 |
rat |
| Chelsey C Damphousse, Jaclyn Medeiros, Diano F Marron. Functional Integration of Adult-Generated Neurons in Diabetic Goto-Kakizaki Rats. Frontiers in behavioral neuroscience. vol 15. 2021-10-23. PMID:34675787. |
adult-born neurons in the dentate gyrus (dg) make important contributions to learning as they integrate into neuronal networks. |
2021-10-23 |
2023-08-13 |
rat |
| Yosef Avchalumov, Robert J Oliver, Wulfran Trenet, Rocio Erandi Heyer Osorno, Britta D Sibley, Dvijen C Purohit, Candice Contet, Marisa Roberto, John J Woodward, Chitra D Mandya. Chronic ethanol exposure differentially alters neuronal function in the medial prefrontal cortex and dentate gyrus. Neuropharmacology. vol 185. 2021-10-21. PMID:33333103. |
here we used chronic intermittent ethanol vapor exposure (cie), 21d protracted abstinence following cie (21d ab), and re-exposure to one vapor session during protracted abstinence (re-exposure) to evaluate the effects of chronic ethanol exposure on basal synaptic function, neuronal excitability and expression of key synaptic proteins that play a role in neuronal excitability in the medial pfc (mpfc) and dentate gyrus (dg). |
2021-10-21 |
2023-08-13 |
Not clear |
| Che Liu, Sang H Lee, Rene Hernandez-Cardenache, David Loewenstein, Josefina Kather, Noam Alperi. Poor sleep is associated with small hippocampal subfields in cognitively normal elderly individuals. Journal of sleep research. vol 30. issue 5. 2021-10-21. PMID:33949039. |
compared to normal sleepers, poor sleepers exhibited significantly lower normalised volumes in the left cornu ammonis field 1 (ca1), dentate gyrus (dg) and subiculum. |
2021-10-21 |
2023-08-13 |
Not clear |
| Keith L Gonzales, Jeanette D Chapleau, Joseph P Pierce, David T Kelter, Tanya J Williams, Annelyn Torres-Reveron, Bruce S McEwen, Elizabeth M Waters, Teresa A Milne. The influences of reproductive status and acute stress on the levels of phosphorylated mu opioid receptor immunoreactivity in rat hippocampus. Frontiers in endocrinology. vol 2. issue 18. 2021-10-21. PMID:22468144. |
in both sexes, pmor-immunoreactivity (ir) was prominent in axons and terminals and in a few neuronal somata and dendrites, some of which contained parv in the mossy fiber pathway region of the dentate gyrus (dg) hilus and ca3 stratum lucidum. |
2021-10-21 |
2023-08-12 |
rat |
| Xiaojuan Yin, Lei Dong, Wei Wei, Yu Wang, Yannan Chai, Zhichun Fen. Effect of mouse nerve growth factor on the expression of glial fibrillary acidic protein in hippocampus of neonatal rats with hypoxic-ischemic brain damage. Experimental and therapeutic medicine. vol 5. issue 2. 2021-10-21. PMID:23408790. |
gfap-positive cells were mainly distributed in the ischemic side of the hippocampal dentate gyrus (dg) region in the mngf group while in the hibd group they were in the ischemic side of the hippocampal ca1 region. |
2021-10-21 |
2023-08-12 |
mouse |
| Ivona Brasnjevic, Roy Lardenoije, Christoph Schmitz, Nicolien Van Der Kolk, Dara L Dickstein, Hisaaki Takahashi, Patrick R Hof, Harry W M Steinbusch, Bart P F Rutte. REGION-SPECIFIC NEURON AND SYNAPSE LOSS IN THE HIPPOCAMPUS OF APP Translational neuroscience. vol 4. issue 1. 2021-10-21. PMID:24829793. |
age-related alterations in total numbers of neurons and in numbers of synaptophysin-immunoreactive presynaptic boutons (sipb), as well as the amyloid plaque load were analyzed in the hippocampal dentate gyrus (dg), ca3, and ca1-2 of 2- and 10-month-old app |
2021-10-21 |
2023-08-13 |
mouse |
| Ashley S Brown, Matthew Wieben, Shelby Murdock, Jill Chang, Maria L V Dizon, Mark St Pierre, Raul Chavez-Valdez, Richard I Dorsky, Camille M Fun. Intrauterine Growth Restriction Causes Abnormal Embryonic Dentate Gyrus Neurogenesis in Mouse Offspring That Leads to Adult Learning and Memory Deficits. eNeuro. vol 8. issue 5. 2021-10-20. PMID:34544755. |
hippocampal dentate gyrus (dg) granule neurons play an important role in memory formation; however, it is unknown whether iugr affects embryonic dg neurogenesis, which could provide a potential mechanism underlying abnormal postnatal learning and memory function. |
2021-10-20 |
2023-08-13 |
mouse |
| Yafei Wang, Zhiheng Lu, Yilan Zhang, Yuqun Cai, Di Yun, Tianxiang Tang, Zheping Cai, Chunyang Wang, Yandong Zhang, Fang Fang, Zhengang Yang, Thomas Behnisch, Yunli Xi. Transcription Factor 4 Safeguards Hippocampal Dentate Gyrus Development by Regulating Neural Progenitor Migration. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 5. 2021-10-19. PMID:31845732. |
the dentate gyrus (dg) of the hippocampal formation plays essential roles in learning and memory. |
2021-10-19 |
2023-08-13 |
mouse |
| Chryssa Bekiari, Ioannis Grivas, Anastasia Tsingotjidou, Georgios C Papadopoulo. Adult neurogenesis and gliogenesis in the dorsal and ventral canine hippocampus. The Journal of comparative neurology. vol 528. issue 7. 2021-10-18. PMID:31743444. |
dentate gyrus (dg) of the mammalian hippocampus gives rise to new neurons and astrocytes all through adulthood. |
2021-10-18 |
2023-08-13 |
human |
| Farbod Torkamand, Ali-Mohammad Aghakhani-Lobnani, Hossein Khaleghzadeh-Ahangar, Mina Rashvand, Mohammad Rahban, Abbas Haghparas. The role of dentate gyrus dopaminergic receptors in the lateral hypothalamic-induced antinociception during persistent inflammatory pain in male rats. Behavioural brain research. vol 412. 2021-10-18. PMID:34175356. |
also, the dentate gyrus (dg) of the hippocampus expresses various receptors, including dopaminergic receptors. |
2021-10-18 |
2023-08-13 |
rat |
| Thomas H Lee, Ahadullah, Brian R Christie, Kangguang Lin, Parco Ming-Fai Siu, Li Zhang, Ti-Fei Yuan, Pragya Komal, Aimin Xu, Kwok-Fai So, Suk-Yu Ya. Chronic AdipoRon Treatment Mimics the Effects of Physical Exercise on Restoring Hippocampal Neuroplasticity in Diabetic Mice. Molecular neurobiology. vol 58. issue 9. 2021-10-15. PMID:34164760. |
besides, adiporon treatment increased progenitor cell proliferation and neuronal differentiation in the hippocampal dentate gyrus (dg) of diabetic mice. |
2021-10-15 |
2023-08-13 |
mouse |
| Sara Mercurio, Chiara Alberti, Linda Serra, Simone Meneghini, Pietro Berico, Jessica Bertolini, Andrea Becchetti, Silvia K Nicoli. An early Sox2-dependent gene expression programme required for hippocampal dentate gyrus development. Open biology. vol 11. issue 2. 2021-10-14. PMID:33622105. |
late sox2 deletion (from e11.5, via nestin-cre) affects only postnatal hippocampal development; earlier deletion (from e10.5, emx1-cre) significantly reduces the dentate gyrus (dg), and the earliest deletion (from e9.5, foxg1-cre) causes drastic abnormalities, with almost complete absence of the dg. |
2021-10-14 |
2023-08-13 |
mouse |
| Yongliang Pan, Qingqing Zhu, Xiaotong Wang, Jiaxin Chen, Boyuan Wen, Zhongshan Zhang, Zuoxin Wan. Agonistic behaviors and neuronal activation in sexually naïve female Mongolian gerbils. Behavioural brain research. vol 395. 2021-10-13. PMID:32798594. |
losers also had more fos-ir cells in the paraventricular nucleus of the hypothalamus (pvn), anterior medial (bstam) and anteriolateral (bstal) subnuclei of the bed nucleus of the stria terminalis (bst), and the ventral subnucleus of the lateral septum (lsv), as well as less fos-ir cells in the dentate gyrus of the hippocampus (dg), compared to the controls. |
2021-10-13 |
2023-08-13 |
Not clear |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Nadia P González-Domínguez, Laura Medina-Cej. Causal relationship of CA3 back-projection to the dentate gyrus and its role in CA1 fast ripple generation. BMC neuroscience. vol 22. issue 1. 2021-10-11. PMID:34001031. |
a loss in this control results in observable oscillatory perturbations called fast ripples, in epileptic rats those events are found in ca1, ca3, and the dentate gyrus (dg), which are the principal regions of the trisynaptic circuit of the hippocampus. |
2021-10-11 |
2023-08-13 |
rat |
| Yasunori Takahashi, Risako Yamashita, Hiromu Okano, Kazumi Takashima, Bunichiro Ogawa, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Gye-Hyeong Woo, Toshinori Yoshida, Makoto Shibutan. Aberrant neurogenesis and late onset suppression of synaptic plasticity as well as sustained neuroinflammation in the hippocampal dentate gyrus after developmental exposure to ethanol in rats. Toxicology. vol 462. 2021-10-11. PMID:34547370. |
at weaning, type-3 neural progenitor cells (npcs) were decreased in the subgranular zone (sgz), accompanied by chrnb2 downregulation and grin2b upregulation in the dentate gyrus (dg). |
2021-10-11 |
2023-08-13 |
rat |