| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Donald J Lehmann, Helga Refsum, Donald R Warden, Christopher Medway, Gordon K Wilcock, A David Smit. The vitamin D receptor gene is associated with Alzheimer's disease. Neuroscience letters. vol 504. issue 2. 2012-02-07. PMID:21911036. |
we also found preliminary evidence of interactions associated with ad between these polymorphisms and two other genes involved in the regulation of inflammation, interleukin-10 (il10) and dopamine β-hydroxylase (dbh): synergy factors ≥3.4, uncorrected p<0.05. |
2012-02-07 |
2023-08-12 |
human |
| Michail Pavlidis, Maria Sundvik, Yu-Chia Chen, Pertti Panul. Adaptive changes in zebrafish brain in dominant-subordinate behavioral context. Behavioural brain research. vol 225. issue 2. 2012-01-24. PMID:21875623. |
expression of genes encoding proteins involved in the functioning of the hypothalamus-hypophysis-interrenal axis (corticotropin releasing factor, crf; glucocorticoid receptor, gr; mineralocorticoid receptor, mr); arginine vasotocin, avt), in the biosynthesis and catabolism of catecholamines (tyrosine hydroxylase, th1 and th2; dopa decarboxylase, ddc), dopamine β-hydroxylase, dbh; catechol-o-methyl transferase, comt), in the biosynthesis of histamine (histidine decarboxylase, hdc) and in the general stress response (galanin, gal; hypocretin/orexin, hcrt) was examined. |
2012-01-24 |
2023-08-12 |
zebrafish |
| Y Fan, J Huang, M Duffourc, R L Kao, G A Ordway, R Huang, M-Y Zh. Transcription factor Phox2 upregulates expression of norepinephrine transporter and dopamine β-hydroxylase in adult rat brains. Neuroscience. vol 192. 2012-01-18. PMID:21763404. |
in the present study, recombinant lentiviral egfp-phox2a and -phox2b (vphox2a and vphox2b) were constructed to study the effects of phox2a/2b over-expression on dopamine β-hydroxylase (dbh) and norepinephrine transporter (net) levels in central noradrenergic neurons. |
2012-01-18 |
2023-08-12 |
rat |
| Ryan S Friese, Geert W Schmid-Schönbein, Daniel T O'Conno. Systematic polymorphism discovery after genome-wide identification of potential susceptibility loci in a hereditary rodent model of human hypertension. Blood pressure. vol 20. issue 4. 2012-01-05. PMID:21428728. |
we identified seven candidate genes that merit resequencing (catechol-o-methyltransferase [comt], chromogranin a [chga], dopamine beta-hydroxylase [dbh], electron transferring flavoprotein dehydrogenase [etfdh], endothelin receptor type b [ednrb], neuropeptide y [npy] and phenylethanolamine-n-methyltransferase [pnmt]), and then discovered polymorphism in four of these seven candidate genes. |
2012-01-05 |
2023-08-12 |
human |
| Flora Tassone, Lihong Qi, Wenting Zhang, Robin L Hansen, Isaac N Pessah, Irva Hertz-Picciott. MAOA, DBH, and SLC6A4 variants in CHARGE: a case-control study of autism spectrum disorders. Autism research : official journal of the International Society for Autism Research. vol 4. issue 4. 2011-12-22. PMID:21538940. |
we examined three loci, serotonin transporter (slc6a4), dopamine β-hydroxylase (dbh), and the variable number of tandem repeat promoter of the monoamine oxidase a (maoa) for association with autism in participants from the childhood autism risks from genetics and the environment (charge ) study, the first large-scale population-based case-control investigation of both environmental and genetic contributions to autism risk. |
2011-12-22 |
2023-08-12 |
human |
| Donna K Hobgoo. Personality traits of aggression-submissiveness and perfectionism associate with ABO blood groups through catecholamine activities. Medical hypotheses. vol 77. issue 2. 2011-11-29. PMID:21601990. |
personality trait research has shown associations with many genes, prominently those of the catecholamine metabolism such as dopamine beta hydroxylase (dbh), catechol-o-methyltransferase (comt), and monoamine oxidase a (maoa). |
2011-11-29 |
2023-08-12 |
Not clear |
| Ting-Kuang Yeh, Ting-Chi Yeh, Chi-Feng Weng, Bing-Fu Shih, Hsueh-Jen Tsao, Chien-Hua Hsiao, Fu-Tai Chuang, Chung-Yi Hu, Chun-Yen Chan. Association of polymorphisms in genes involved in the dopaminergic pathway with blood pressure and uric acid levels in Chinese females. Journal of neural transmission (Vienna, Austria : 1996). vol 117. issue 12. 2011-11-14. PMID:20931244. |
systolic blood pressure and diastolic blood pressure were associated significantly with the catechol-o-methyltransferase (comt) val158met polymorphism and the dopamine β-hydroxylase (dbh) c1021t polymorphism. |
2011-11-14 |
2023-08-12 |
human |
| Mateusz Siedlinski, Michael H Cho, Per Bakke, Amund Gulsvik, David A Lomas, Wayne Anderson, Xiangyang Kong, Stephen I Rennard, Terri H Beaty, John E Hokanson, James D Crapo, Edwin K Silverma. Genome-wide association study of smoking behaviours in patients with COPD. Thorax. vol 66. issue 10. 2011-11-08. PMID:21685187. |
previous genome-wide association studies (gwas) have identified numerous single nucleotide polymorphisms (snps) associated with the number of cigarettes smoked per day (cpd) and a dopamine beta-hydroxylase (dbh) locus associated with smoking cessation in multiple populations. |
2011-11-08 |
2023-08-12 |
Not clear |
| Chiho Sumi-Ichinose, Hiroshi Ichinose, Kazuhisa Ikemoto, Takahide Nomura, Kazunao Kond. Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: regulation of dopaminergic neural transmission by tyrosine hydroxylase protein at nerve terminals. Journal of pharmacological sciences. vol 114. issue 1. 2011-08-11. PMID:20716859. |
in order to probe the role of bh(4) in vivo, we established bh(4)-depleted mice by disrupting the 6-pyruvoyltetrahydropterin synthase (pts) gene (pts(-/-)) and rescued them by introducing human pts cdna under the control of the human dopamine β-hydroxylase (dbh) promoter (pts(-/-)-dps). |
2011-08-11 |
2023-08-12 |
mouse |
| Yangha Kim, Eun-Ha Choi, Miae Doo, Joo-Yeon Kim, Chul-Jin Kim, Chong-Tai Kim, In-Hwan Ki. Anti-stress effects of ginseng via down-regulation of tyrosine hydroxylase (TH) and dopamine β-hydroxylase (DBH) gene expression in immobilization-stressed rats and PC12 cells. Nutrition research and practice. vol 4. issue 4. 2011-07-14. PMID:20827341. |
anti-stress effects of ginseng via down-regulation of tyrosine hydroxylase (th) and dopamine β-hydroxylase (dbh) gene expression in immobilization-stressed rats and pc12 cells. |
2011-07-14 |
2023-08-12 |
rat |
| Yangha Kim, Eun-Ha Choi, Miae Doo, Joo-Yeon Kim, Chul-Jin Kim, Chong-Tai Kim, In-Hwan Ki. Anti-stress effects of ginseng via down-regulation of tyrosine hydroxylase (TH) and dopamine β-hydroxylase (DBH) gene expression in immobilization-stressed rats and PC12 cells. Nutrition research and practice. vol 4. issue 4. 2011-07-14. PMID:20827341. |
it is well established that long-term stress leads to the induction of catecholamine biosynthetic enzymes such as tyrosine hydroxylase (th) and dopamine β-hydroxylase (dbh) in adrenal medulla. |
2011-07-14 |
2023-08-12 |
rat |
| Seok Jong Hong, Yang Hoon Huh, Amanda Leung, Hyun Jin Choi, Yunmin Ding, Un Jung Kang, Seung Hyun Yoo, Reinhard Buettner, Kwang-Soo Ki. Transcription factor AP-2β regulates the neurotransmitter phenotype and maturation of chromaffin cells. Molecular and cellular neurosciences. vol 46. issue 1. 2011-07-05. PMID:20875861. |
in adrenal chromaffin cells of the ap-2β(-/-) mouse, the expression levels of catecholamine biosynthesizing enzymes, dopamine β-hydroxylase (dbh) and phenylethanolamine-n-methyl-transferase (pnmt), as well as the sa-specific transcription factor, phox2b, are significantly reduced compared to wild type. |
2011-07-05 |
2023-08-12 |
mouse |
| Noèlia Fernàndez-Castillo, Marta Ribasés, Carlos Roncero, Miquel Casas, Begoña Gonzalvo, Bru Corman. Association study between the DAT1, DBH and DRD2 genes and cocaine dependence in a Spanish sample. Psychiatric genetics. vol 20. issue 6. 2011-06-02. PMID:20505554. |
we genotyped the int8 and 3'utr variable number of tandem repeats of the dopamine transporter gene (dat1/slc6a3), the taqia (rs1800497) and taqib (rs1079597) snp polymorphisms within the dopamine receptor d2 gene and the 19-bp insertion/deletion and c.444g>a (rs1108580) polymorphisms of the dopamine β-hydroxylase gene (dbh) in a spanish sample of 169 patients with cocaine addiction and 169 sex-matched controls. |
2011-06-02 |
2023-08-12 |
Not clear |
| Chun-Hyung Kim, Amanda Leung, Yang Hoon Huh, Eungi Yang, Deog-Joong Kim, Pierre Leblanc, Hoon Ryu, Kyungjin Kim, Dong-Wook Kim, Emily M Garland, Satish R Raj, Italo Biaggioni, David Robertson, Kwang-Soo Ki. Norepinephrine deficiency is caused by combined abnormal mRNA processing and defective protein trafficking of dopamine beta-hydroxylase. The Journal of biological chemistry. vol 286. issue 11. 2011-05-16. PMID:21209083. |
human norepinephrine (ne) deficiency (or dopamine β-hydroxylase (dbh) deficiency) is a rare congenital disorder of primary autonomic failure, in which neurotransmitters ne and epinephrine are undetectable. |
2011-05-16 |
2023-08-12 |
human |
| L I Serova, R Nostramo, M Veerasirikul, D B Cappell, E L Sabba. Varied mechanisms of oestradiol-mediated regulation of dopamine β-hydroxylase transcription. Journal of neuroendocrinology. vol 23. issue 2. 2011-05-05. PMID:21062376. |
experiments performed in vivo and in cell culture have demonstrated that oestradiol induces dopamine β-hydroxylase (dbh) gene transcription. |
2011-05-05 |
2023-08-12 |
rat |
| Pamela J McMillan, Sylvia S White, Allyn Franklin, J Lynne Greenup, James B Leverenz, Murray A Raskind, Patricia Szo. Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease. Brain research. vol 1373. 2011-05-03. PMID:21147074. |
tyrosine hydroxylase (th) and dopamine β-hydroxylase (dbh) mrna expression in postmortem lc tissue of control and age-matched pd subjects demonstrated a significant reduction in the number of noradrenergic neurons in the lc of pd subjects. |
2011-05-03 |
2023-08-12 |
human |
| Kensuke Kimura, Hideaki Kanazawa, Masaki Ieda, Haruko Kawaguchi-Manabe, Yoshiko Miyake, Takashi Yagi, Takahide Arai, Motoaki Sano, Keiichi Fukud. Norepinephrine-induced nerve growth factor depletion causes cardiac sympathetic denervation in severe heart failure. Autonomic neuroscience : basic & clinical. vol 156. issue 1-2. 2011-04-26. PMID:20335077. |
the cardiac sympathetic fiber loss was also confirmed in ne-exposed dbh (dopamine beta-hydroxylase)-cre/floxed-egfp (enhanced green fluorescent protein) mice with severe chf, in which sympathetic nerve could be traced by egfp. |
2011-04-26 |
2023-08-12 |
mouse |
| Zhi Zhou, Lingling Wang, Jialong Yang, Huan Zhang, Pengfei Kong, Mengqiang Wang, Limei Qiu, Linsheng Son. A dopamine beta hydroxylase from Chlamys farreri and its induced mRNA expression in the haemocytes after LPS stimulation. Fish & shellfish immunology. vol 30. issue 1. 2011-04-20. PMID:20933600. |
dopamine beta hydroxylase (dbh) is a critical enzyme in the biosynthesis of catecholamines, and also plays an important role in complex neuroendocrine-immune regulatory network. |
2011-04-20 |
2023-08-12 |
Not clear |
| G Brousse, F Vorspan, K Ksouda, V Bloch, K Peoc'h, J L Laplanche, S Mouly, J Schmidt, P M Llorca, J P Lepin. Could the inter-individual variability in cocaine-induced psychotic effects influence the development of cocaine addiction? Towards a new pharmacogenetic approach to addictions. Medical hypotheses. vol 75. issue 6. 2011-02-18. PMID:20801583. |
several studies have looked for a link between cocaine addiction and the genes of the dopaminergic system: the genes drd2, comt, slc6a3 (coding for the dopamine transporter dat) and dbh (coding for the dopamine beta hydroxylase) but unfortunately very few well established results. |
2011-02-18 |
2023-08-12 |
Not clear |
| Jason P Schroeder, Debra A Cooper, Jesse R Schank, Megan A Lyle, Meriem Gaval-Cruz, Yvonne E Ogbonmwan, Nikita Pozdeyev, Kimberly G Freeman, P Michael Iuvone, Gaylen L Edwards, Philip V Holmes, David Weinshenke. Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine β-hydroxylase. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 12. 2011-02-16. PMID:20736996. |
we hypothesized that disulfiram's inhibition of dopamine β-hydroxylase (dbh), the catecholamine biosynthetic enzyme that converts dopamine (da) to norepinephrine (ne) in noradrenergic neurons, underlies the drug's ability to treat cocaine dependence. |
2011-02-16 |
2023-08-12 |
rat |