| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuqing Chen, Kuixing Zhang, Gen Wen, Fangwen Rao, Amber P Sanchez, Lei Wang, Juan L Rodriguez-Flores, Manjula Mahata, Sushil K Mahata, Jill Waalen, Michael G Ziegler, Bruce A Hamilton, Daniel T O'Conno. Human dopamine β-hydroxylase promoter variant alters transcription in chromaffin cells, enzyme secretion, and blood pressure. American journal of hypertension. vol 24. issue 1. 2011-02-11. PMID:20814407. |
dopamine β-hydroxylase (dbh) plays an indispensable role in catecholamine synthesis by converting dopamine into norepinephrine. |
2011-02-11 |
2023-08-12 |
human |
| B Dudas, M Baker, G Rotoli, G Grignol, M C Bohn, I Merchenthale. Distribution and morphology of the catecholaminergic neural elements in the human hypothalamus. Neuroscience. vol 171. issue 1. 2011-02-02. PMID:20801195. |
since the different catecholaminergic systems can be detected by identifying the neurons containing the specific key enzymes of catecholaminergic synthesis, in the present study we mapped the catecholaminergic elements in the human hypothalamus using immunohistochemistry against the catecholaminergic enzymes, th, dopamine beta-hydroxylase (dbh) and phenylethanolamine-n-methyltransferase (pnmt). |
2011-02-02 |
2023-08-12 |
human |
| Kasia Radwanska, Evgenij Nikolaev, Leszek Kaczmare. Central noradrenergic lesion induced by DSP-4 impairs the acquisition of avoidance reactions and prevents molecular changes in the amygdala. Neurobiology of learning and memory. vol 94. issue 3. 2011-01-27. PMID:20650329. |
we found that dsp-4 treatment depleted the expression of the norepinephrine marker dopamine -hydroxylase (dbh) in the locus coeruleus and its projection area, the basolateral nucleus of the amygdala, confirming locus coeruleus noradrenergic lesion in the experimental animals. |
2011-01-27 |
2023-08-12 |
rat |
| Onofre Combarros, Donald R Warden, Naomi Hammond, Mario Cortina-Borja, Olivia Belbin, Michael G Lehmann, Gordon K Wilcock, Kristelle Brown, Patrick G Kehoe, Rachel Barber, Eliecer Coto, Victoria Alvarez, Panos Deloukas, Rhian Gwilliam, Reinhard Heun, Heike Kölsch, Ignacio Mateo, Abderrahim Oulhaj, Alejandro Arias-Vásquez, Maaike Schuur, Yurii S Aulchenko, M Arfan Ikram, Monique M Breteler, Cornelia M van Duijn, Kevin Morgan, A David Smith, Donald J Lehman. The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project. BMC medical genetics. vol 11. 2010-12-30. PMID:21070631. |
dopamine β-hydroxylase (dbh) catalyses the conversion of dopamine to noradrenaline. |
2010-12-30 |
2023-08-12 |
Not clear |
| Pingyuan Gong, Anyun Zheng, Kejin Zhang, Xu Lei, Fengchao Li, Dongmei Chen, Wanyu Chi, Xueli Tong, Zijian Zheng, Xiaocai Gao, Fuchang Zhan. Association analysis between 12 genetic variants of ten genes and personality traits in a young chinese Han population. Journal of molecular neuroscience : MN. vol 42. issue 1. 2010-12-20. PMID:20464528. |
in the study, we selected some functional variations in ten candidate genes (comt, dbh, drd(2), drd(3), dat, maoa, grm(1), grin2b, 5-th(2a), and 5-th(6)) encoding components in dopamine, glutamate, and 5-hydroxytryptamine pathways. |
2010-12-20 |
2023-08-12 |
human |
| J NouriNezhad, K Wasowicz, R Bukowski, C Skobowia. Analysis of the chemical coding of neurons in the intermediate thoracic ganglion of the pig. Polish journal of veterinary sciences. vol 13. issue 3. 2010-12-07. PMID:21033570. |
the localization and pattern of distribution of nerve cell bodies and fibers containing tyrosine hydroxylase (th), dopamine b-hydroxylase (dbh), neuropeptide y (npy), vasoactive intestinal polypeptide (vip), somatostatin (som), galanin (gal), methionine-enkephalin (met) as well as calcitonin gene-related peptide (cgrp), substance p (sp) and pituitary adenylate cyclase-activating peptide (pacap) was studied with immunohistochemistry. |
2010-12-07 |
2023-08-12 |
Not clear |
| D Russo, C Bombardi, A Grandis, J B Furness, A Spadari, C Bernardini, R Chiocchett. Sympathetic innervation of the ileocecal junction in horses. The Journal of comparative neurology. vol 518. issue 19. 2010-12-06. PMID:20737599. |
immunoreactivity (ir) for tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), neuronal nitric oxide synthase (nnos), calcitonin gene-related peptide (cgrp), substance p (sp), and neuropeptide y (npy) was investigated. |
2010-12-06 |
2023-08-12 |
Not clear |
| A K M H Kober, M Aoyama, S Sugit. Immunohistochemical localization of catecholamine biosynthetic enzymes in the adrenal gland of the domestic fowl (Gallus domesticus). Poultry science. vol 89. issue 8. 2010-12-03. PMID:20634527. |
the present study investigated the cellular localization of 3 catecholamine biosynthetic enzymes, tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), and phenylethanolamine n-methyltransferase (pnmt) to identify and analyze the localization of norepinephrine (ne) and epinephrine (e) cells in the adrenal gland in the chicken using peroxidase-antiperoxidase immunohistochemical techniques. |
2010-12-03 |
2023-08-12 |
chicken |
| Stéphane F Maison, Mina Le, Erik Larsen, Suh-Kyung Lee, John J Rosowski, Steven A Thomas, M Charles Liberma. Mice lacking adrenergic signaling have normal cochlear responses and normal resistance to acoustic injury but enhanced susceptibility to middle-ear infection. Journal of the Association for Research in Otolaryngology : JARO. vol 11. issue 3. 2010-11-22. PMID:20503062. |
to assess the functional role of adrenergic signaling in the auditory periphery, we studied mice with targeted deletion of the gene for dopamine beta-hydroxylase (dbh), which catalyzes the conversion of dopamine to noradrenaline; thus, these mutant mice have no measurable adrenaline or noradrenaline. |
2010-11-22 |
2023-08-12 |
mouse |
| Ciara M Greene, Ian H Robertson, Michael Gill, Mark A Bellgrov. Dopaminergic genotype influences spatial bias in healthy adults. Neuropsychologia. vol 48. issue 9. 2010-10-20. PMID:20430042. |
homozygosity for the dbh t allele, which is associated with relatively increased dopamine and decreased noradrenaline levels, resulted in a significant increase in rightwards spatial bias relative to the c allele. |
2010-10-20 |
2023-08-12 |
human |
| Mette Skinbjerg, Nicholas Seneca, Jeih-San Liow, Jinsoo Hong, David Weinshenker, Victor W Pike, Christer Halldin, David R Sibley, Robert B Inni. Dopamine beta-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding. Synapse (New York, N.Y.). vol 64. issue 9. 2010-10-19. PMID:20336622. |
deletion of the gene for dopamine beta-hydroxylase (dbh) causes mice to become hypersensitive to the effects of psychostimulants, and in vitro radioligand binding results suggest an increased percentage of d(2) receptors in a high-affinity state. |
2010-10-19 |
2023-08-12 |
mouse |
| Nipa Bhaduri, Kanyakumarika Sarkar, Swagata Sinha, Anindita Chattopadhyay, Kanchan Mukhopadhya. Study on DBH genetic polymorphisms and plasma activity in attention deficit hyperactivity disorder patients from Eastern India. Cellular and molecular neurobiology. vol 30. issue 2. 2010-10-06. PMID:19757024. |
synthesis of norepinephrine from dopamine is catalyzed by the enzyme dopamine beta-hydroxylase and numerous polymorphisms in the dbh gene have been found to exert their direct influence on the enzyme activity independently. |
2010-10-06 |
2023-08-12 |
human |
| Sohan Punia, Mitashree Das, Madhuri Behari, Bikash K Mishra, Asish K Sahani, Shyla T Govindappa, Sachi Jayaram, Uday B Muthane, Thelma B K, Ramesh C Juya. Role of polymorphisms in dopamine synthesis and metabolism genes and association of DBH haplotypes with Parkinson's disease among North Indians. Pharmacogenetics and genomics. vol 20. issue 7. 2010-09-20. PMID:20498626. |
role of polymorphisms in dopamine synthesis and metabolism genes and association of dbh haplotypes with parkinson's disease among north indians. |
2010-09-20 |
2023-08-12 |
Not clear |
| Surekha Rani Panjala, Steven A Thomas, Jena J Steinl. Effects of insulin-like growth factor-1 (IGF-1) receptor signaling on rates of apoptosis in retina of dopamine beta hydroxylase (Dbh-/-) knockout mice. Autonomic neuroscience : basic & clinical. vol 152. issue 1-2. 2010-04-29. PMID:19748322. |
we have investigated whether insulin-like growth factor-1 (igf-1) receptor signaling alters rates of apoptosis in dopamine beta-hydroxylase (dbh(-/-)) knockout mice. |
2010-04-29 |
2023-08-12 |
mouse |
| Xiaoli Zhang, Junda Su, Asheebo Rojas, Chun Jian. Pontine norepinephrine defects in Mecp2-null mice involve deficient expression of dopamine beta-hydroxylase but not a loss of catecholaminergic neurons. Biochemical and biophysical research communications. vol 394. issue 2. 2010-04-22. PMID:20193660. |
although deficiency in tyrosine hydroxylase (th) has been demonstrated, it is possible that dopamine beta-hydroxylase (dbh), the critical enzyme converting dopamine to ne, is also affected. |
2010-04-22 |
2023-08-12 |
mouse |
| A Erez, J Li, M T Geraghty, S Ben-Shachar, M L Cooper, D E Mensing, K D Vonalt, Z Ou, A N Pursley, A C Chinault, A Patel, S W Cheung, T Saho. Mosaic deletion 11p13 in a child with dopamine beta-hydroxylase deficiency--case report and review of the literature. American journal of medical genetics. Part A. vol 152A. issue 3. 2010-04-12. PMID:20186791. |
dopamine beta-hydroxylase (dbh) deficiency is characterized by a lack of sympathetic noradrenergic function. |
2010-04-12 |
2023-08-12 |
Not clear |
| Esther L Sabban, Shreekrishna Maharjan, Regina Nostramo, Lidia I Serov. Divergent effects of estradiol on gene expression of catecholamine biosynthetic enzymes. Physiology & behavior. vol 99. issue 2. 2010-04-05. PMID:19638280. |
estradiol directly regulated promoter activity of th, gtpch and dopamine beta-hydroxylase (dbh) genes. |
2010-04-05 |
2023-08-12 |
rat |
| Ivo Paclt, Jitka Koudelová, Dagmar Pacltova, Marta Kopeckov. Dopamine beta hydroxylase (DBH) plasma activity in childhood mental disorders. Neuro endocrinology letters. vol 30. issue 5. 2010-03-31. PMID:20035263. |
dopamine beta hydroxylase (dbh) plasma activity in childhood mental disorders. |
2010-03-31 |
2023-08-12 |
Not clear |
| Cristiano G Moreira, David Weinshenker, Vanessa Sperandi. QseC mediates Salmonella enterica serovar typhimurium virulence in vitro and in vivo. Infection and immunity. vol 78. issue 3. 2010-03-26. PMID:20028809. |
additionally, dopamine beta-hydroxylase knockout (dbh(-)(/)(-)) mice that do not produce epi or ne showed different susceptibility to salmonella serovar typhimurium infection than wild-type mice. |
2010-03-26 |
2023-08-12 |
mouse |
| Yuqing Chen, Gen Wen, Fangwen Rao, Kuixing Zhang, Lei Wang, Juan L Rodriguez-Flores, Amber P Sanchez, Manjula Mahata, Laurent Taupenot, Ping Sun, Sushil K Mahata, Bamidele Tayo, Nicholas J Schork, Michael G Ziegler, Bruce A Hamilton, Daniel T O'Conno. Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure. Journal of hypertension. vol 28. issue 1. 2010-03-09. PMID:20009769. |
human dopamine beta-hydroxylase (dbh) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure. |
2010-03-09 |
2023-08-12 |
human |