| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Idaira Oliva, Miriam Fernández, Eduardo D Martí. Dopamine release regulation by astrocytes during cerebral ischemia. Neurobiology of disease. vol 58. 2014-04-23. PMID:23800715. |
our data indicate that ischemia induces massive release of da by dual mechanisms: one which operates via vesicular exocytosis and is action potential dependent and another involving reverse transport by the dopamine transporter (dat). |
2014-04-23 |
2023-08-12 |
mouse |
| Idaira Oliva, Miriam Fernández, Eduardo D Martí. Dopamine release regulation by astrocytes during cerebral ischemia. Neurobiology of disease. vol 58. 2014-04-23. PMID:23800715. |
simultaneous blockade of astrocyte glutamate transporters and dat prevented the massive release of dopamine and reduced the brain tissue damage. |
2014-04-23 |
2023-08-12 |
mouse |
| G Thomsen, M Ziebell, P S Jensen, S da Cuhna-Bang, G M Knudsen, L H Pinbor. No correlation between body mass index and striatal dopamine transporter availability in healthy volunteers using SPECT and [123I]PE2I. Obesity (Silver Spring, Md.). vol 21. issue 9. 2014-04-22. PMID:23696269. |
in striatum, dopamine is inactivated by reuptake via the dopamine transporter (dat). |
2014-04-22 |
2023-08-12 |
human |
| Linda D Simmler, Anna Rickli, York Schramm, Marius C Hoener, Matthias E Liecht. Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives. Biochemical pharmacology. vol 88. issue 2. 2014-04-22. PMID:24486525. |
we investigated norepinephrine (ne), dopamine (da), and serotonin (5-hydroxytryptamine [5-ht]) uptake inhibition using human embryonic kidney 293 (hek 293) cells that express the respective human monoamine transporters (net, dat, and sert). |
2014-04-22 |
2023-08-12 |
human |
| Oluyomi M Okunola-Bakare, Jianjing Cao, Theresa Kopajtic, Jonathan L Katz, Claus J Loland, Lei Shi, Amy Hauck Newma. Elucidation of structural elements for selectivity across monoamine transporters: novel 2-[(diphenylmethyl)sulfinyl]acetamide (modafinil) analogues. Journal of medicinal chemistry. vol 57. issue 3. 2014-04-15. PMID:24494745. |
2-[(diphenylmethyl)sulfinyl]acetamide (modafinil, (±)-1) is a unique dopamine uptake inhibitor that binds the dopamine transporter (dat) differently than cocaine and may have potential for the treatment of psychostimulant abuse. |
2014-04-15 |
2023-08-12 |
Not clear |
| Ike C dela Peña, Seo Young Yoon, Yeni Kim, Haeil Park, Kyeong Man Kim, Jong Hoon Ryu, Chan Young Shin, Jae Hoon Cheon. 5,7-Dihydroxy-6-methoxy-4'-phenoxyflavone, a derivative of oroxylin A improves attention-deficit/hyperactivity disorder (ADHD)-like behaviors in spontaneously hypertensive rats. European journal of pharmacology. vol 715. issue 1-3. 2014-04-14. PMID:23707903. |
among all oroxylin a analogs, compound 7-7 (5,7-dihydroxy-6-methoxy-4'-phenoxyflavone) showed the most remarkable inhibition of dopamine reuptake alike methylphenidate, a dopamine transporter (dat) blocker and typical drug for adhd, and oroxylin a. |
2014-04-14 |
2023-08-12 |
rat |
| Craig P Motbey, Kelly J Clemens, Nadine Apetz, Adam R Winstock, John Ramsey, Kong M Li, Naomi Wyatt, Paul D Callaghan, Michael T Bowen, Jennifer L Cornish, Iain S McGrego. High levels of intravenous mephedrone (4-methylmethcathinone) self-administration in rats: neural consequences and comparison with methamphetamine. Journal of psychopharmacology (Oxford, England). vol 27. issue 9. 2014-04-08. PMID:23739178. |
brains were analyzed ex vivo for striatal serotonin (5-ht) and dopamine (da) levels and metabolites, while autoradiography assessed changes in the regional density of 5-ht and serotonin transporter (sert) and da transporter (dat) and induction of the inflammation marker translocator protein (tspo). |
2014-04-08 |
2023-08-12 |
rat |
| S R Suwijn, H W Berendse, C V M Verschuur, R M A de Bie, J Booi. Serotonin transporter availability in early stage Parkinson's disease and multiple system atrophy. ISRN neurology. vol 2014. 2014-04-02. PMID:24693450. |
we retrospectively assessed baseline midbrain sert availability as well as midbrain sert-to-striatal dopamine transporter (dat) ratios. |
2014-04-02 |
2023-08-13 |
Not clear |
| V Narayanaswami, A C Thompson, L A Cassis, M T Bardo, L P Dwoski. Diet-induced obesity: dopamine transporter function, impulsivity and motivation. International journal of obesity (2005). vol 37. issue 8. 2014-03-31. PMID:23164701. |
a rat model of diet-induced obesity (dio) was used to determine dopamine transporter (dat) function, impulsivity and motivation as neurobehavioral outcomes and predictors of obesity. |
2014-03-31 |
2023-08-12 |
rat |
| Gianluigi Tanda, Su Min Li, Maddalena Mereu, Alexandra M Thomas, Aaron L Ebbs, Lauren E Chun, Valeria Tronci, Jennifer L Green, Mu-Fa Zou, Theresa A Kopajtic, Amy Hauck Newman, Jonathan L Kat. Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change. Psychopharmacology. vol 229. issue 2. 2014-03-31. PMID:23612854. |
dopamine transporter (dat) conformation plays a role in the effectiveness of cocaine-like and other dat inhibitors. |
2014-03-31 |
2023-08-12 |
rat |
| L R F Faro, I M Oliveira, R Durán, M Alfons. In vivo neurochemical characterization of clothianidin induced striatal dopamine release. Toxicology. vol 302. issue 2-3. 2014-03-28. PMID:22967792. |
to investigate the involvement of dopamine transporter (dat), the effect of clo was observed in presence of nomifensine. |
2014-03-28 |
2023-08-12 |
rat |
| Susanna Jakobson Mo, Anne Larsson, Jan Linder, Richard Birgander, Lars Edenbrandt, Hans Stenlund, Lars Forsgren, Katrine Riklun. ¹²³I-FP-Cit and 123I-IBZM SPECT uptake in a prospective normal material analysed with two different semiquantitative image evaluation tools. Nuclear medicine communications. vol 34. issue 10. 2014-03-27. PMID:23903558. |
the need for age-adjusted and/or sex-adjusted reference values in dopamine transporter (dat) and dopamine d2 receptor (d2r) imaging with single-photon emission computed tomography (spect) in a longitudinal study of parkinsonian diseases was investigated. |
2014-03-27 |
2023-08-12 |
Not clear |
| Alexander K Converse, Colleen F Moore, Jeffrey M Moirano, Elizabeth O Ahlers, Julie A Larson, Jonathan W Engle, Todd E Barnhart, Dhanabalan Murali, Bradley T Christian, Onofre T DeJesus, James E Holden, Robert J Nickles, Mary L Schneide. Prenatal stress induces increased striatal dopamine transporter binding in adult nonhuman primates. Biological psychiatry. vol 74. issue 7. 2014-03-25. PMID:23726316. |
to determine the effects in adult offspring of maternal exposure to stress and alcohol during pregnancy, we imaged striatal and midbrain dopamine transporter (dat) binding by positron emission tomography in rhesus monkeys (macaca mulatta). |
2014-03-25 |
2023-08-12 |
monkey |
| Alexander K Converse, Colleen F Moore, Jeffrey M Moirano, Elizabeth O Ahlers, Julie A Larson, Jonathan W Engle, Todd E Barnhart, Dhanabalan Murali, Bradley T Christian, Onofre T DeJesus, James E Holden, Robert J Nickles, Mary L Schneide. Prenatal stress induces increased striatal dopamine transporter binding in adult nonhuman primates. Biological psychiatry. vol 74. issue 7. 2014-03-25. PMID:23726316. |
we also evaluated the relationship between dat binding and behavioral responses previously found to relate to dopamine d2 receptor density (responsivity to tactile stimuli, performance on a learning task, and behavior during a learning task). |
2014-03-25 |
2023-08-12 |
monkey |
| Valerie Voon, Alexandra Rizos, Riddhika Chakravartty, Nicola Mulholland, Stephanie Robinson, Nicholas A Howell, Neil Harrison, Gill Vivian, K Ray Chaudhur. Impulse control disorders in Parkinson's disease: decreased striatal dopamine transporter levels. Journal of neurology, neurosurgery, and psychiatry. vol 85. issue 2. 2014-03-24. PMID:23899625. |
we compared pd patients with impulse control disorders and age-matched and gender-matched controls without impulse control disorders using [(123)i]fp-cit (2β-carbomethoxy-3β-(4-iodophenyl)tropane) single photon emission computed tomography (spect), to assess striatal dopamine transporter (dat) density. |
2014-03-24 |
2023-08-12 |
Not clear |
| Andreina Pauli, Diana P Prata, Andrea Mechelli, Marco Picchioni, Cynthia H Y Fu, Christopher A Chaddock, Fergus Kane, Sridevi Kalidindi, Colm McDonald, Eugenia Kravariti, Timothea Toulopoulou, Elvira Bramon, Muriel Walshe, Natascha Ehlert, Anna Georgiades, Robin Murray, David A Collier, Philip McGuir. Interaction between effects of genes coding for dopamine and glutamate transmission on striatal and parahippocampal function. Human brain mapping. vol 34. issue 9. 2014-03-20. PMID:22438288. |
the genes for the dopamine transporter (dat) and the d-amino acid oxidase activator (daoa or g72) have been independently implicated in the risk for schizophrenia and in bipolar disorder and/or their related intermediate phenotypes. |
2014-03-20 |
2023-08-12 |
human |
| Andreina Pauli, Diana P Prata, Andrea Mechelli, Marco Picchioni, Cynthia H Y Fu, Christopher A Chaddock, Fergus Kane, Sridevi Kalidindi, Colm McDonald, Eugenia Kravariti, Timothea Toulopoulou, Elvira Bramon, Muriel Walshe, Natascha Ehlert, Anna Georgiades, Robin Murray, David A Collier, Philip McGuir. Interaction between effects of genes coding for dopamine and glutamate transmission on striatal and parahippocampal function. Human brain mapping. vol 34. issue 9. 2014-03-20. PMID:22438288. |
dat and g72 respectively modulate central dopamine and glutamate transmission, the two systems most robustly implicated in these disorders. |
2014-03-20 |
2023-08-12 |
human |
| Andreina Pauli, Diana P Prata, Andrea Mechelli, Marco Picchioni, Cynthia H Y Fu, Christopher A Chaddock, Fergus Kane, Sridevi Kalidindi, Colm McDonald, Eugenia Kravariti, Timothea Toulopoulou, Elvira Bramon, Muriel Walshe, Natascha Ehlert, Anna Georgiades, Robin Murray, David A Collier, Philip McGuir. Interaction between effects of genes coding for dopamine and glutamate transmission on striatal and parahippocampal function. Human brain mapping. vol 34. issue 9. 2014-03-20. PMID:22438288. |
using functional magnetic resonance imaging we examined whether there was an interaction between the effects of genes that influence dopamine and glutamate transmission (dat and g72) on regional brain activation during verbal fluency, which is known to be abnormal in psychosis, in 80 healthy volunteers. |
2014-03-20 |
2023-08-12 |
human |
| Amanda L Brown, Trevor A Day, Christopher V Dayas, Doug W Smit. Purity and enrichment of laser-microdissected midbrain dopamine neurons. BioMed research international. vol 2013. 2014-03-18. PMID:23984404. |
for the dopamine transporter (dat) and the vesicular monoamine transporter type 2 (vmat2), average enrichments were approximately 100- and 60-fold, respectively. |
2014-03-18 |
2023-08-12 |
Not clear |
| Mauro Federici, Emanuele Claudio Latagliata, Ada Ledonne, Francesca R Rizzo, Marco Feligioni, Dave Sulzer, Matthew Dunn, Dalibor Sames, Howard Gu, Robert Nisticò, Stefano Puglisi-Allegra, Nicola B Mercur. Paradoxical abatement of striatal dopaminergic transmission by cocaine and methylphenidate. The Journal of biological chemistry. vol 289. issue 1. 2014-03-17. PMID:24280216. |
in contrast to the classical dopamine transporter (dat)-dependent enhancement of the dopaminergic signal observed at concentrations of cocaine lower than 3 μm, the inhibitory effect of cocaine was found at concentrations higher than 3 μm. |
2014-03-17 |
2023-08-12 |
mouse |