| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Illiano, C E Bass, L Fichera, L Mus, E A Budygin, T D Sotnikova, D Leo, S Espinoza, R R Gainetdino. Recombinant Adeno-Associated Virus-mediated rescue of function in a mouse model of Dopamine Transporter Deficiency Syndrome. Scientific reports. vol 7. 2018-11-27. PMID:28417953. |
dopamine transporter deficiency syndrome (dtds) is a rare autosomal recessive disorder caused by loss-of-function mutations in dopamine transporter (dat) gene, leading to severe neurological disabilities in children and adults. |
2018-11-27 |
2023-08-13 |
mouse |
| Yu-Hua Tian, Shi-Xun Ma, Kwang-Wook Lee, Sunmee Wee, George F Koob, Seok-Yong Lee, Choon-Gon Jan. Blockade of TRPV1 Inhibits Methamphetamine-induced Rewarding Effects. Scientific reports. vol 8. issue 1. 2018-11-27. PMID:29343767. |
furthermore, attenuated dopamine transporter (dat) binding levels in the nac and dst regions of map-induced cpp mice were reversed by cpz. |
2018-11-27 |
2023-08-13 |
mouse |
| Takuya Fukuoka, Yoshihiko Nakazato, Masaomi Yamamoto, Akifumi Miyake, Takashi Mitsufuji, Toshimasa Yamamot. Fatal Familial Insomnia Initially Developing Parkinsonism Mimicking Dementia with Lewy Bodies. Internal medicine (Tokyo, Japan). vol 57. issue 18. 2018-11-26. PMID:29709939. |
we evaluated the function of the striatum via dopamine transporter single-photon emission computed tomography (dat spect) using |
2018-11-26 |
2023-08-13 |
Not clear |
| Panayotis K Thanos, Jianmin Zhuo, Lisa Robison, Ronald Kim, Mala Ananth, Ilon Choai, Adam Grunseich, Nicola M Grissom, Robert George, Foteini Delis, Teresa M Reye. Suboptimal maternal diets alter mu opioid receptor and dopamine type 1 receptor binding but exert no effect on dopamine transporters in the offspring brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 64. 2018-11-15. PMID:27666382. |
in vitro autoradiography was used to measure mu-opioid receptor (mor), dopamine type 1 receptor (d1r), and dopamine transporter (dat) binding level in mesolimbic brain regions. |
2018-11-15 |
2023-08-13 |
mouse |
| Brendan J Tunstall, Chelsea P Ho, Jianjing Cao, Janaína C M Vendruscolo, Brooke E Schmeichel, Rachel D Slack, Gianluigi Tanda, Alexandra J Gadiano, Rana Rais, Barbara S Slusher, George F Koob, Amy H Newman, Leandro F Vendruscol. Atypical dopamine transporter inhibitors attenuate compulsive-like methamphetamine self-administration in rats. Neuropharmacology. vol 131. 2018-11-13. PMID:29217282. |
similar to meth, the wake-promoting drug (r)-modafinil (r-mod) binds to the dopamine transporter (dat). |
2018-11-13 |
2023-08-13 |
rat |
| Ross McFarland, Zi Teng Wang, Yan Jouroukhin, Ye Li, Olga Mychko, Isabelle Coppens, Jianchun Xiao, Lorraine Jones-Brando, Robert H Yolken, L David Sibley, Mikhail V Pletniko. AAH2 gene is not required for dopamine-dependent neurochemical and behavioral abnormalities produced by Toxoplasma infection in mouse. Behavioural brain research. vol 347. 2018-11-13. PMID:29555339. |
we found that chronic t. gondii infection of balb/c mice leads to blunted response to amphetamine or cocaine and decreased expression of dopamine transporter (dat) and vesicular monoamine transporter 2 (vmat2). |
2018-11-13 |
2023-08-13 |
mouse |
| Felix P Mayer, Nadine V Burchardt, Ann M Decker, John S Partilla, Yang Li, Gavin McLaughlin, Pierce V Kavanagh, Walter Sandtner, Bruce E Blough, Simon D Brandt, Michael H Baumann, Harald H Sitt. Fluorinated phenmetrazine "legal highs" act as substrates for high-affinity monoamine transporters of the SLC6 family. Neuropharmacology. vol 134. issue Pt A. 2018-11-07. PMID:28988906. |
here we tested 3-fpm and its positional isomers, 2-fpm and 4-fpm, for their abilities to interact with plasma membrane monoamine transporters for dopamine (dat), norepinephrine (net) and serotonin (sert). |
2018-11-07 |
2023-08-13 |
Not clear |
| Katarzyna Kamińska, Karolina Noworyta-Sokołowska, Anna Górska, Joanna Rzemieniec, Agnieszka Wnuk, Adam Wojtas, Grzegorz Kreiner, Małgorzata Kajta, Krystyna Gołembiowsk. The Effects of Exposure to Mephedrone During Adolescence on Brain Neurotransmission and Neurotoxicity in Adult Rats. Neurotoxicity research. vol 34. issue 3. 2018-11-06. PMID:29713996. |
mephedrone by its interaction with transporters for dopamine (dat) and serotonin (sert) stimulates their release to the synaptic cleft. |
2018-11-06 |
2023-08-13 |
mouse |
| Kyoungjune Pak, Hyun-Yeol Nam, Seunghyeon Shin, Keunyoung Kim, Myung Jun Lee, Eun-Joo Kim, Jae Meen Lee, Seong-Jang Kim, In Joo Ki. Effects of rs591323 on serotonin transporter availability in healthy male subjects. Annals of nuclear medicine. vol 32. issue 7. 2018-11-06. PMID:29774458. |
we aimed to investigate the association between genetic factors of snps dopamine transporter (dat) and serotonin transporter (sert) availabilities in healthy controls. |
2018-11-06 |
2023-08-13 |
human |
| Danielle O Sambo, Min Lin, Anthony Owens, Joseph J Lebowitz, Ben Richardson, Darin A Jagnarine, Madhur Shetty, Meghan Rodriquez, Taiwo Alonge, Mishaal Ali, Jonathan Katz, Long Yan, Marcelo Febo, L Keith Henry, Adriaan W Bruijnzeel, Lynette Daws, Habibeh Khoshboue. The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission. Nature communications. vol 8. issue 1. 2018-11-05. PMID:29263318. |
dopamine neurotransmission is highly dysregulated by the psychostimulant methamphetamine, a substrate for the dopamine transporter (dat). |
2018-11-05 |
2023-08-13 |
Not clear |
| Danielle O Sambo, Min Lin, Anthony Owens, Joseph J Lebowitz, Ben Richardson, Darin A Jagnarine, Madhur Shetty, Meghan Rodriquez, Taiwo Alonge, Mishaal Ali, Jonathan Katz, Long Yan, Marcelo Febo, L Keith Henry, Adriaan W Bruijnzeel, Lynette Daws, Habibeh Khoshboue. The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission. Nature communications. vol 8. issue 1. 2018-11-05. PMID:29263318. |
through interactions with dat, methamphetamine increases extracellular dopamine levels in the brain, leading to its rewarding and addictive properties. |
2018-11-05 |
2023-08-13 |
Not clear |
| Marc Morissette, Nicolas Morin, Claude Rouillard, Thérèse Di Paol. Membrane cholesterol removal and replenishment affect rat and monkey brain monoamine transporters. Neuropharmacology. vol 133. 2018-11-05. PMID:29407218. |
the dopamine transporter (dat) is abundantly expressed in the striatum where it removes extracellular dopamine into the cytosol of presynaptic nerve terminals. |
2018-11-05 |
2023-08-13 |
rat |
| Koh Tadokoro, Yasuyuki Ohta, Kota Sato, Takahiro Maeki, Ryo Sasaki, Yoshiaki Takahashi, Jingwei Shang, Mami Takemoto, Nozomi Hishikawa, Toru Yamashita, Chang Kweng Lim, Shigeru Tajima, Koji Ab. A Japanese Encephalitis Patient Presenting with Parkinsonism with Corresponding Laterality of Magnetic Resonance and Dopamine Transporter Imaging Findings. Internal medicine (Tokyo, Japan). vol 57. issue 15. 2018-11-05. PMID:29526949. |
dopamine transporter (dat) imaging using |
2018-11-05 |
2023-08-13 |
Not clear |
| Vincent Chin-Hung Chen, Chun-Ching Chiu, Li-Jeng Chen, Tsai-Ching Hsu, Bor-Show Tzan. Effects of taurine on striatal dopamine transporter expression and dopamine uptake in SHR rats. Behavioural brain research. vol 348. 2018-11-05. PMID:29694913. |
this study investigates the effect of taurine on the shr striatum by detecting the spontaneous alternation, da transporter (dat) level, dopamine uptake and brain-derived neurotrophic factor (bdnf) expression. |
2018-11-05 |
2023-08-13 |
rat |
| Vincent Chin-Hung Chen, Chun-Ching Chiu, Li-Jeng Chen, Tsai-Ching Hsu, Bor-Show Tzan. Effects of taurine on striatal dopamine transporter expression and dopamine uptake in SHR rats. Behavioural brain research. vol 348. 2018-11-05. PMID:29694913. |
these findings indicate that different dosages of taurine have opposite effects on striatal dat expression and dopamine uptake, suggesting high-dose taurine as a possible candidate for adhd treatment. |
2018-11-05 |
2023-08-13 |
rat |
| Sathya Challasivakanaka, Juan Zhen, Margaret E Smith, Maarten E A Reith, James D Foster, Roxanne A Vaugha. Dopamine transporter phosphorylation site threonine 53 is stimulated by amphetamines and regulates dopamine transport, efflux, and cocaine analog binding. The Journal of biological chemistry. vol 292. issue 46. 2018-10-29. PMID:28939767. |
the dopamine transporter (dat) controls the spatial and temporal dynamics of dopamine neurotransmission through reuptake of extracellular transmitter and is a target for addictive compounds such as cocaine, amphetamine (amph), and methamphetamine (meth). |
2018-10-29 |
2023-08-13 |
rat |
| Katherine Coulombe, Olivier Kerdiles, Cyntia Tremblay, Vincent Emond, Manon Lebel, Anne-Sophie Boulianne, Mélanie Plourde, Francesca Cicchetti, Frédéric Calo. Impact of DHA intake in a mouse model of synucleinopathy. Experimental neurology. vol 301. issue Pt A. 2018-10-24. PMID:29229294. |
thy1-αsyn mice displayed impaired motor skills, lower dopaminergic neuronal counts within the substantia nigra (-13%) in parallel to decreased levels of the striatal dopamine transporter (dat) (-24%), as well as reduced neun (-41%) and synaptic proteins psd-95 (-51%), synaptophysin (-80%) and vesicular acetylcholine transporter (vchat) (-40%) in the cerebral cortex compared to c57/bl6 mice. |
2018-10-24 |
2023-08-13 |
mouse |
| Luísa Becker Bertotto, Jaben Richards, Jay Gan, David Christopher Volz, Daniel Schlen. Effects of bifenthrin exposure on the estrogenic and dopaminergic pathways in zebrafish embryos and juveniles. Environmental toxicology and chemistry. vol 37. issue 1. 2018-10-22. PMID:28815728. |
quantitative reverse transcriptase polymerase chain reaction was used to investigate transcripts of tyrosine hydroxylase (th), dopamine receptor 1 (dr1) and 2a (dr2a), dopamine active transporter (dat), estrogen receptor α (erα), erβ1, erβ2, luteinizing hormone β (lhβ), follicle-stimulating hormone β (fshβ), vitellogenin (vtg), cytochrome p450 cyp19a1a, and cyp19a1b. |
2018-10-22 |
2023-08-13 |
zebrafish |
| Naveed Malek, Ravi Jampana, Donald G Grosse. Rare case of atypical parkinsonism: why family history is important. Scottish medical journal. vol 62. issue 4. 2018-10-22. PMID:29192564. |
magnetic resonance imaging scan of the brain was normal and a dat spect scan showed reduced dopamine uptake in the basal ganglia. |
2018-10-22 |
2023-08-13 |
Not clear |
| Anna Rieckmann, Keith A Johnson, Reisa A Sperling, Randy L Buckner, Trey Hedde. Dedifferentiation of caudate functional connectivity and striatal dopamine transporter density predict memory change in normal aging. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 40. 2018-10-16. PMID:30224467. |
here, we used fmri to measure functional connectivity of caudate subfields with large-scale association networks and positron emission tomography to measure striatal dopamine transporter (dat) density in 51 older adults (age 65-86 years) who received annual cognitive testing for up to 7 years (mean = 5.59, range 2-7 years). |
2018-10-16 |
2023-08-13 |
Not clear |