| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christian Jansen, Anna Schröder, Robert Schueler, Jennifer Lehmann, Michael Praktiknjo, Frank E Uschner, Robert Schierwagen, Daniel Thomas, Sofia Monteiro, Georg Nickenig, Christian P Strassburg, Carsten Meyer, Vicente Arroyo, Christoph Hammerstingl, Jonel Trebick. Left Ventricular Longitudinal Contractility Predicts Acute-on-Chronic Liver Failure Development and Mortality After Transjugular Intrahepatic Portosystemic Shunt. Hepatology communications. vol 3. issue 3. 2020-09-29. PMID:30984902. |
lv-gls was independently associated with overall mortality (hazard ratio [hr], 1.123; 95% confidence interval [ci],1.010-1.250) together with aspartate aminotransferase (hr, 1.009; 95% ci, 1.004-1.014) and clif-c ad score (hr, 1.080; 95% ci, 1.018-1.137). |
2020-09-29 |
2023-08-13 |
Not clear |
| Tran Thi Khanh Tuong, Dang Khoa Tran, Pham Quang Thien Phu, Tong Nguyen Diem Hong, Thien Chu Dinh, Dinh Toi Ch. Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes: Evaluation of Hepatic Fibrosis and Steatosis Using Fibroscan. Diagnostics (Basel, Switzerland). vol 10. issue 3. 2020-09-28. PMID:32183383. |
on multivariate analysis, aspartate aminotransferase (ast) (or: 1.067; 95% ci: 1.017-1.119; p = 0.008) and platelet levels (or: 0.985; 95% ci: 0.972-0.999; p = 0.034) were independent of risk factors of advanced fibrosis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Mohammad Parohan, Sajad Yaghoubi, Asal Seraj. Liver injury is associated with severe coronavirus disease 2019 (COVID-19) infection: A systematic review and meta-analysis of retrospective studies. Hepatology research : the official journal of the Japan Society of Hepatology. vol 50. issue 8. 2020-09-28. PMID:32386449. |
higher serum levels of aspartate aminotransferase (weighted mean difference, 8.84 u/l; 95% confidence interval [ci] 5.97 to 11.71; p < 0.001), alanine aminotransferase (weighted mean difference, 7.35 u/l; 95% ci, 4.77 to 9.93; p < 0.001), total bilirubin (weighted mean difference, 2.30 mmol/l; 95% ci, 1.24 to 3.36; p < 0.001), and lower serum levels of albumin (weighted mean difference, -4.24 g/l; 95% ci, -6.20 to -2.28; p < 0.001) were associated with a significant increase in the severity of covid-19 infection. |
2020-09-28 |
2023-08-13 |
human |
| Mingchun Ou, Jieyun Zhu, Pan Ji, Hongyuan Li, Zhimei Zhong, Bocheng Li, Jielong Pang, Jianfeng Zhang, Xiaowen Zhen. Risk factors of severe cases with COVID-19: a meta-analysis. Epidemiology and infection. vol 148. 2020-08-27. PMID:32782035. |
patients with severe disease showed significantly lower platelet count (wmd = -18.63, 95%ci -30.86 to -6.40) and lymphocyte count (wmd = -0.35, 95%ci -0.41 to -0.30) but higher c-reactive protein (crp; wmd = 42.7, 95%ci 31.12-54.28), lactate dehydrogenase (ldh; wmd = 137.4, 95%ci 105.5-169.3), white blood cell count（wbc), procalcitonin（pct）, d-dimer, alanine aminotransferase (alt), aspartate aminotransferase (ast) and creatinine（cr）. |
2020-08-27 |
2023-08-13 |
Not clear |
| Neal S Parikh, Hooman Kamel, Babak B Navi, Costantino Iadecola, Alexander E Merkler, Arun Jesudian, Jesse Dawson, Guido J Falcone, Kevin N Sheth, David J Roh, Mitchell S V Elkind, Daniel F Hanley, Wendy C Ziai, Santosh B Murth. Liver Fibrosis Indices and Outcomes After Primary Intracerebral Hemorrhage. Stroke. vol 51. issue 3. 2020-06-19. PMID:31906832. |
after adjusting for potential confounders, aspartate aminotransferase-platelet ratio index was associated with hematoma volume (β, 0.20 [95% ci, 0.04-0.36]), hematoma expansion (odds ratio, 1.6 [95% ci, 1.1-2.3]), and mortality (odds ratio, 1.8 [95% ci, 1.1-2.7]). |
2020-06-19 |
2023-08-13 |
Not clear |
| Tannous K Fakhry, Rahul Mhaskar, Theresa Schwitalla, Elnara Muradova, John Paul Gonzalvo, Michel M Mur. Bariatric surgery improves nonalcoholic fatty liver disease: a contemporary systematic review and meta-analysis. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. vol 15. issue 3. 2020-03-20. PMID:30683512. |
similarly, aspartate aminotransferase (ast) improved in 32% of patients (95% ci: .22, .42) and alanine aminotransferase improved in 62% of patients (95% ci: .42, .82). |
2020-03-20 |
2023-08-13 |
Not clear |
| Rui Fan, Jufang Wang, Jinman D. Association between body mass index and fatty liver risk: A dose-response analysis. Scientific reports. vol 8. issue 1. 2019-12-10. PMID:30323178. |
after adjusting for confounding factors (age, gender, hypertension, total cholesterol, triglycerides, glucose, high-density lipoprotein, low-density lipoprotein, uric acid, homocysteine, creatinine, aspartate aminotransferase and alanine transaminase), overweight (or = 3.55, 95% ci: 2.49-5.06, p = 2.79 × 10 |
2019-12-10 |
2023-08-13 |
Not clear |
| Chengshuo Zhang, Jianzhen Lin, Feng Li, Yue Li, Baofeng Jiang, Han Bai, Jialin Zhan. Effect of ω-3 polyunsaturated fatty acids on liver function and inflammatory reaction in patients undergoing hepatectomy: a systematic review and meta-analysis of randomized control trials. Expert review of gastroenterology & hepatology. vol 13. issue 4. 2019-06-25. PMID:30791756. |
ω-3 pufas significantly reduced alanine aminotransferase [mean difference (md): -68.82, 95% confidence interval (ci): -108.55 to - 29.08; p = 0.0007]; aspartate aminotransferase (md: -64.92, 95% ci: -112.87 to -16.98; p = 0.008), white blood cell count (md: -1.22, 95% ci: -2.15 to -0.29; p = 0.01) and increased the level of pre-albumin on postoperative day 3 (md: 10.42, 95% ci: 4.84 to 15.99; p = 0.0002). |
2019-06-25 |
2023-08-13 |
Not clear |
| Yousuke Taniguchi, Kenichi Sakakura, Yusuke Adachi, Naoyuki Akashi, Yusuke Watanabe, Masamitsu Noguchi, Kei Yamamoto, Yusuke Ugata, Hiroshi Wada, Shin-Ichi Momomura, Hideo Fujit. In-hospital outcomes of acute myocardial infarction with cardiogenic shock caused by right coronary artery occlusion vs. left coronary artery occlusion. Cardiovascular intervention and therapeutics. vol 33. issue 4. 2019-06-17. PMID:28918455. |
aspartate transaminase value (per 50 u/l incremental: or 1.22, 95% ci 1.03-1.45, p = 0.02), aging (per 10-year-old incremental: or 2.14, 95% ci 1.26-3.63, p = 0.01) and using va-ecmo (or 22.13, 95% ci 5.22-93.90, p < 0.001) were also significantly associated with in-hospital death. |
2019-06-17 |
2023-08-13 |
Not clear |
| Shu-Qi Yao, Wei Yi, Rong Liu, Neng-Gui X. [Development of research on mechanisms of electroacupuncture intervention underlying improvement of cerebral ischemia rats in recent five years]. Zhen ci yan jiu = Acupuncture research. vol 44. issue 5. 2019-06-07. PMID:31155874. |
outcomes showed that both ea preconditioning and regular intervention could relieve ci by reducing toxicity of excitatory amino acids (glutamate, aspartate) and tlr4/nf-κb-mediated inflammatory cascade reaction to relieve inflammatory injury. |
2019-06-07 |
2023-08-13 |
rat |
| Xu Liu, Jing Meng, Hongqin Xu, Junqi Ni. Alpha-fetoprotein to transaminase ratio is related to higher diagnostic efficacy for hepatocellular carcinoma. Medicine. vol 98. issue 17. 2019-05-20. PMID:31027143. |
the area under the receiver-operating curve (auroc) of afp, afp/(aspartate aminotransferase*alanine aminotransferase) [afp/(ast*alt)] and afp/wbc were compared between the hcc group and the control groups for the quantifying diagnostic efficacy.aurocs of our novel index afp/(ast*alt) were up to 0.853 (95% confidence interval, ci 0.818-0.887, p < .001) and 0.825 (95% ci 0.782-0.868, p < .001), respectively, when differentiating hcc from non-hcc patients and from cirrhosis patients, which was superior to afp and afp/wbc. |
2019-05-20 |
2023-08-13 |
human |
| Da Jiang, Jian Shi, Meng Yuan, Xiaoyang Duan, Lihua Li, Qian L. Levels of serum bilirubin in small cell lung cancer and non-small cell lung cancer patients. Cellular and molecular biology (Noisy-le-Grand, France). vol 64. issue 6. 2018-11-07. PMID:29808804. |
multi-classification logistics regression analysis revealed low total bilirubin level [or (95%ci), 1.12 (1.02-1.23)], aspartate transaminase [or (95%ci), 1.12 (1.02-1.23)], and alanine transaminase [or (95%ci), 1.12 (1.02-1.23)] were risk factors in lung cancer. |
2018-11-07 |
2023-08-13 |
human |
| Fariborz Mansour-Ghanaei, Amir Hadi, Makan Pourmasoumi, Farahnaz Joukar, Sahar Golpour, Ameneh Najafgholizade. Green tea as a safe alternative approach for nonalcoholic fatty liver treatment: A systematic review and meta-analysis of clinical trials. Phytotherapy research : PTR. vol 32. issue 10. 2018-10-31. PMID:29947156. |
the meta-analysis of data from four studies indicated significant effects of green tea supplementation in altering alanine aminotransferases (-12.81 u/l; 95% ci: -18.17 to -7.45) and aspartate aminotransferases (-10.91 u/l; 95% ci: -19.66 to -2.17) blood concentrations. |
2018-10-31 |
2023-08-13 |
Not clear |
| Zheming Yu, Hamed Samavat, Allison M Dostal, Renwei Wang, Carolyn J Torkelson, Chung S Yang, Lesley M Butler, Thomas W Kensler, Anna H Wu, Mindy S Kurzer, Jian-Min Yua. Effect of Green Tea Supplements on Liver Enzyme Elevation: Results from a Randomized Intervention Study in the United States. Cancer prevention research (Philadelphia, Pa.). vol 10. issue 10. 2018-05-29. PMID:28765194. |
among women in the gte arm, alanine aminotransferase (alt) increased by 5.4 u/l [95% confidence interval (ci), 3.6-7.1] and aspartate aminotransferase increased by 3.8 u/l (95% ci, 2.5-5.1), which were significantly higher than those among women in the placebo arm (both |
2018-05-29 |
2023-08-13 |
human |
| Junfeng Liu, Deren Wang, Jie Li, Yao Xiong, Bian Liu, Chenchen Wei, Simiao Wu, Ming Li. High Serum Alkaline Phosphatase Levels in Relation to Multi-Cerebral Microbleeds in Acute Ischemic Stroke Patients with Atrial Fibrillation and/or Rheumatic Heart Disease. Current neurovascular research. vol 13. issue 4. 2017-10-19. PMID:27538890. |
compared with the first tertile of alp concentration, participants in the third tertile were 3.59 times more likely to have multi-cmbs (≥2) [95% confidence interval (ci): 1.21-10.71; p = 0.02] after adjusting for age, gender, smoking habits, drinking habits, alt (alanine transaminase) levels, ast (aspartate transaminase) levels, renal impairment and cwmh. |
2017-10-19 |
2023-08-13 |
human |
| Hung-Sheng Huang, Chien-Chin Hsu, Je-Chiuan Ye, Shih-Bin Su, Chien-Cheng Huang, Hung-Jung Li. Predicting the mortality in geriatric patients with dengue fever. Medicine. vol 96. issue 37. 2017-09-22. PMID:28906367. |
the following 4 independent mortality predictors were identified: severe coma [glasgow coma scale: ≤8; adjusted odds ratio (aor): 11.36; 95% confidence interval (ci): 1.89-68.19], bedridden (aor: 10.46; 95% ci: 1.58-69.16), severe hepatitis (aspartate aminotransferase >1000 u/l; aor: 96.08; 95% ci: 14.11-654.40), and renal failure (serum creatinine >2 mg/dl; aor: 6.03; 95% ci: 1.50-24.24). |
2017-09-22 |
2023-08-13 |
Not clear |
| Seema Gulati, Anoop Misra, Rajneesh Tiwari, Meenu Sharma, Ravindra M Pandey, Chander Prakash Yada. Effect of high-protein meal replacement on weight and cardiometabolic profile in overweight/obese Asian Indians in North India. The British journal of nutrition. vol 117. issue 11. 2017-07-31. PMID:28653586. |
additional improvement in mean values for the following parameters in the hpmr group compared with the control group was observed: body weight, 4·9 % (95 % ci 3·8, 6·1; p<0·001); wc, 3·8 % (95 % ci 2·5, 5·1; p<0·001); %bf, 6·3 % (95 % ci 4·3, 8·2; p<0·001); systolic blood pressure, 2·8 % (95 % ci 0·4, 5·1; p=0·002); diastolic blood pressure, 3·5 % (95 % ci 0·7, 6·3; p= 0·01); post-ogtt blood glucose, 7·3 % (95 % ci 1·4, 13·1; p=0·02); total cholesterol, 2·5 % (95 % ci 1·6, 3·5; p<0·001); ldl-cholesterol, 7·3 % (95 % ci 1·7, 12·9; p<0·01); alanine aminotransferase, 22·0 % (95 % ci 2·1, 42; p=0·03) and aspartate aminotransferase, 15·2 % (95 % ci 0·9, 29·5; p=0·04). |
2017-07-31 |
2023-08-13 |
Not clear |
| Diego H Caceres, Angela M Tobón, Angela Ahlquist Cleveland, Christina M Scheel, Dedsy Y Berbesi, Jesús Ochoa, Angela Restrepo, Mary E Brandt, Tom Chiller, Beatriz L Góme. Clinical and Laboratory Profile of Persons Living with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome and Histoplasmosis from a Colombian Hospital. The American journal of tropical medicine and hygiene. vol 95. issue 4. 2017-05-25. PMID:27481056. |
results showed that the patients with pdh were more likely to have karnofsky score ≤ 30 (prevalence ratio [pr] = 1.98, 95% confidence interval [ci] = 0.97-4.06), liver compromised with hepatomegaly and/or splenomegaly (pr = 1.77, ci = 1.03-3.06) and elevation in serum of alanine aminotransferase and aspartate aminotransferase to values > 40 mu/ml (pr = 2.06, ci = 1.09-3.88 and pr = 1.53, ci = 0.99-2.35, respectively). |
2017-05-25 |
2023-08-13 |
human |
| Hyejin Lee, Dong Wook Shin, Tae Hoon Lee, Hyung-Kook Yang, Eunmi Ahn, Jae-Moon Yoon, Hyun-Ki Lee, Beomseok Suh, Ki Young Son, Jun Suk Kim, BeLong Ch. Association Between Change in Serum Aminotransferase and Mortality: A Nationwide Cohort Study in Korea. Medicine. vol 95. issue 12. 2016-08-01. PMID:27015199. |
in contrast, the normalization group (ahr 1.52, 95% ci 0.82-2.81 for aspartate aminotransferase [ast]; ahr 1.35, 95% ci 0.70-2.61 for alanine aminotransferase [alt]) and the new elevation group (ahr 1.27, 0.66-2.44 for ast; ahr 0.99, 95% ci 0.49-2.20 for alt) were not different from the sustained normal group in cvd mortality.individuals with serum aminotransferase elevation, particularly when sustained, are at higher risk of mortality, and should receive appropriate medical attention. |
2016-08-01 |
2023-08-13 |
Not clear |
| Tapan Dey, Kabita Gogoi, Balagopalan Unni, Moonmee Bharadwaz, Munmi Kalita, Dibyajyoti Ozah, Manoj Kalita, Jatin Kalita, Pranab Kumar Baruah, Thaneswar Bor. Role of environmental pollutants in liver physiology: special references to peoples living in the oil drilling sites of Assam. PloS one. vol 10. issue 4. 2016-01-26. PMID:25874634. |
the increase in nitrogen dioxide level was also associated with increase in aspartate transaminase level (p<0.0001) by 2.5 times (95% ci 1.862-3.313) in the exposed group as compared to control group. |
2016-01-26 |
2023-08-13 |
human |