Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xuemei Ding, Xiulin Wen, Liying Wang, Ting Chen, Guangxia Zhou, Hairong He, Xia Xi. Effects of a pneumatic tube system on the hemolysis of blood samples: a PRISMA-compliant meta-analysis. Scandinavian journal of clinical and laboratory investigation. vol 81. issue 5. 2021-11-15. PMID:34109899. |
no significant differences were found between the pts and manual-transportation groups in the hemolysis rate [rr: 0.99, 95% confidence interval (ci): 0.57 to 1.70], hemolysis index (smd: 0.19, 95% ci: -0.00 to 0.38), or level of potassium (smd: 0.05, 95% ci: -0.03 to 0.12), alanine aminotransferase (smd: 0.00, 95% ci: -0.10 to 0.11), or aspartate aminotransferase (smd: 0.04, 95% ci: -0.08 to 0.17). |
2021-11-15 |
2023-08-13 |
Not clear |
Huanhuan Liu, Dandan Zhang, Huawei Lin, Qi Zhang, Ling Zheng, Yuxin Zheng, Xiaolong Yin, Zuanfang Li, Shengxiang Liang, Saie Huan. Meta-Analysis of Neurochemical Changes Estimated via Magnetic Resonance Spectroscopy in Mild Cognitive Impairment and Alzheimer's Disease. Frontiers in aging neuroscience. vol 13. 2021-11-10. PMID:34744689. |
it showed that during the progression from mci to ad, n-acetyl aspartate (naa) decreased continuously in the posterior cingulate (pc) (smd: -0.42 [95% ci: -0.62 to -0.21], |
2021-11-10 |
2023-08-13 |
Not clear |
Sutopa Talukdar, Vipa Thanachartwet, Varunee Desakorn, Supat Chamnanchanunt, Duangjai Sahassananda, Mukda Vangveeravong, Siripen Kalayanarooj, Anan Wattanathu. Predictors of plasma leakage among dengue patients in Thailand: A plasma-leak score analysis. PloS one. vol 16. issue 7. 2021-11-03. PMID:34324559. |
multivariate analysis showed three independent factors associated with plasma leakage, including body mass index ≥25.0 kg/m2 (odds ratio [or] = 1.784; 95% confidence interval [ci] = 1.040-3.057; p = 0.035), platelet count <100,000/mm3 on fever days 3 to 4 (or = 2.151; 95% ci = 1.269-3.647; p = 0.004), and aspartate aminotransferase or alanine aminotransferase ≥100 u/l on fever days 3 to 4 (or = 2.189; 95% ci = 1.231-3.891; p = 0.008). |
2021-11-03 |
2023-08-13 |
Not clear |
Kazuki Yoshimura, Shun-Ichi Kimura, Masakatsu Kawamura, Shunto Kawamura, Junko Takeshita, Nozomu Yoshino, Yukiko Misaki, Ayumi Gomyo, Shimpei Matsumi, Yu Akahoshi, Masaharu Tamaki, Machiko Kusuda, Kazuaki Kameda, Hidenori Wada, Koji Kawamura, Miki Sato, Kiriko Terasako-Saito, Aki Tanihara, Hideki Nakasone, Shinichi Kako, Yoshinobu Kand. Chronic liver graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients during tapering or after stopping calcineurin inhibitors. International journal of hematology. vol 114. issue 6. 2021-11-01. PMID:34378178. |
peak aspartate aminotransferase and alanine aminotransferase levels were higher in patients with liver gvhd during low-dose ci period than in other periods. |
2021-11-01 |
2023-08-13 |
Not clear |
Taxiarchis Botsis, Valsamo K Anagnostou, Gunnar Hartvigsen, George Hripcsak, Chunhua Wen. Developing a multivariable prognostic model for pancreatic endocrine tumors using the clinical data warehouse resources of a single institution. Applied clinical informatics. vol 1. issue 1. 2021-10-20. PMID:21552466. |
distant metastases, aspartate aminotransferase-ast and surgical resection (hr=3.39, 95% ci: 1.38-8.35, p=0.008, hr=3.73, 95% ci: 1.20-11.57, p=0.023 and hr=0.20, 95% ci: 0.08-0.51, p<0.001 respectively) were the strongest predictors in the univariate analysis. |
2021-10-20 |
2023-08-12 |
Not clear |
Shou-Ching Tang, Carter L Capra, Germame H Ajebo, Judith Meza-Junco, Simon Mairs, Barbara S Craft, Xiaofu Zhu, Nita Maihle, William B Hillegas. Systemic toxicities of trastuzumab-emtansine predict tumor response in HER2+ metastatic breast cancer. International journal of cancer. 2021-08-19. PMID:33844843. |
adjusted for baseline platelet count, aspartate transaminase and alanine transaminase, higher tss remains significantly associated with longer progression-free survival with adjusted hr = 0.67 [95% ci: 0.47-0.93], p = .020. |
2021-08-19 |
2023-08-13 |
Not clear |
Jing Wang, Zequn Lu, Meng Jin, Ying Wang, Kunming Tian, Jun Xiao, Yimin Cai, Yanan Wang, Xu Zhang, Tao Chen, Zhi Yao, Chunguang Yang, Renli Deng, Qiang Zhong, Xiongbo Deng, Xin Chen, Xiang-Ping Yang, Gonghong Wei, Zhihua Wang, Jianbo Tian, Xiao-Ping Che. Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center retrospective cohort study. Frontiers of medicine. 2021-08-16. PMID:34387851. |
in addition to previously reported liver impairment markers, such as alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, and total bilirubin, we identified several novel risk factors including elevated lactate dehydrogenase (⩾ 245 u/l, hazard ratio (hr) = 8.639, 95% confidence interval (ci) = 2.528-29.523; p < 0.001) and coagulation-related biomarker d-dimer (⩾ 0.5 µg/ml, hr = 4.321, 95% ci = 1.443-12.939; p = 0.009) and decreased albumin (< 35 g/l, hr = 0.131, 95% ci = 0.048-0.361; p < 0.001) and albumin/globulin ratio (< 1.5, hr = 0.123, 95% ci = 0.017-0.918; p = 0.041). |
2021-08-16 |
2023-08-13 |
Not clear |
Zuyin Li, Weixing Shen, Gang Wu, Changjiang Qin, Yijie Zhang, Yupeng Wang, Guohe Song, Chao Xiao, Xin Zhang, Guilong Deng, Ruitao Wang, Xiaoliang Wan. The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms. FEBS open bio. vol 11. issue 7. 2021-07-13. PMID:33728819. |
carriers of the rs738491 t allele or rs2073082 g allele of samm50 exhibit increased susceptibility to nafld [odds ratio (or) = 1.39; 95% confidence interval (ci) = 1.14-1.71, p = 0.001; or = 1.31; 95% ci = 1.05-1.62, p = 0.016, respectively] and are correlated with elevated serum triglyceride, alanine aminotransferase and aspartate aminotransferase levels. |
2021-07-13 |
2023-08-13 |
human |
Jason Wagner, Victor Garcia-Rodriguez, Abraham Yu, Barbara Dutra, Scott Larson, Brooks Cash, Andrew DuPont, Ahmad Faroo. Elevated transaminases and hypoalbuminemia in Covid-19 are prognostic factors for disease severity. Scientific reports. vol 11. issue 1. 2021-05-28. PMID:33986318. |
in this retrospective, single institution, cohort study that analyzed patients admitted to a community academic hospital with the diagnosis of covid-19, we found that elevations of aspartate aminotransferase (ast), alanine aminotransferase (alt) and alkaline phosphatase (ap) at any time during hospital admission increased the odds of icu admission by 5.12 (95% ci: 1.55-16.89; p = 0.007), 4.71 (95% ci: 1.51-14.69; p = 0.01) and 4.12 (95% ci: 1.21-14.06, p = 0.02), respectively. |
2021-05-28 |
2023-08-13 |
Not clear |
Chang Suk Noh, Won-Young Kim, Moon Seong Bae. Risk factors associated with the need for oxygen therapy in patients with COVID-19. Medicine. vol 100. issue 18. 2021-05-13. PMID:33950987. |
in a multivariate logistic regression analysis, being a current smoker (odds ratio [or] 7.641, 95% confidence interval [ci] 1.686-34.630, p = .008), heart rate (or 1.053, 95% ci 1.010-1.097, p = .014), aspartate aminotransferase values (or 1.049, 95% ci 1.008-1.092, p = .020), blood urea nitrogen levels (or 1.171, 95% ci 1.073-1.278, p < .001), and chest radiographic findings (or 3.173, 95% ci 1.870-5.382, p < .001) were associated with oxygen therapy.in patients with less severe covid-19, the need for oxygen therapy is affected by smoking and elevated values of aspartate aminotransferase and blood urea nitrogen. |
2021-05-13 |
2023-08-13 |
Not clear |
Guifen Xu, Feizhen Chen, Wenxiang Zhao, Yong Zheng, Wei Zhuang, Fuling Y. Establishment and assessment of a nomogram model for predicting the risk of fulminant myocarditis: A STROBE compliant cross-sectional study. Medicine. vol 100. issue 17. 2021-05-04. PMID:33907091. |
due to strong correlation, 6 factors were retained, including mean arterial pressure (or, 95% ci, p: .82, .72-.94, .005), creatinine (2.15, 1.13-4.10, 0.020), blood urea nitrogen (1.45, 1.04-2.02, 0.028), aspartate aminotransferase (2.62, 1.16-5.91, 0.021), troponin i (1.43, 1.07-1.90, 0.015), and ventricular wall motion abnormality (25.81, 2.52-264.69, 0.006). |
2021-05-04 |
2023-08-13 |
Not clear |
Zhongying Han, Junfeng Zhu, Zheng Ha. Evaluation of astragaloside IV in hepatic fibrosis: A meta-analysis. Medicine. vol 100. issue 13. 2021-04-14. PMID:33787592. |
the meta-analysis suggested that aspartate aminotransferase (ast) in model group was more than that in astragaloside group (md = -39.94, 95% ci [-129.38, 49.50], p = .38; i2 = 100%). |
2021-04-14 |
2023-08-13 |
rat |
Yun Huang, Yuyu Zhang, Lili M. Meta-analysis of laboratory results in patients with severe coronavirus disease 2019. Experimental and therapeutic medicine. vol 21. issue 5. 2021-03-23. PMID:33747184. |
the results demonstrated that the incidence of leukocytosis, lymphocytopenia, increased procalcitonin (pct), c-reactive protein (crp), aspartate aminotransferase (ast) and lactic dehydrogenase (ldh) levels was associated with a nearly 3-fold (or=3.44; 95% ci: 2.15-5.49), 4-fold (or=4.39; 95% ci: 1.82-10.60), 5-fold (or=5.28; 95% ci: 3.42-8.15), 4-fold (or=3.99; 95% ci: 2.61-6.12), 3-fold (or=3.02; 95% ci: 2.13-4.26) and 8-fold (or=8.33; 95% ci: 1.75-39.69) higher risk of severe covid-19 infection, respectively. |
2021-03-23 |
2023-08-13 |
Not clear |
S A Boytsov, N V Pogosova, F N Paleev, M V Ezhov, A L Komarov, D V Pevsner, K A Gruzdev, I V Barinova, A Yu Suvorov, I A Alekseeva, O V Milk. Clinical Characteristics and Factors Associated with Poor Outcomes in Hospitalized Patients with Novel Coronavirus Infection COVID-19. Kardiologiia. vol 61. issue 2. 2021-03-22. PMID:33734042. |
according to results of the multivariate regression analysis, three most significant predictors of the hard endpoint, all-cause death during the stay in the hospital, were more than 5-fold increases in aspartate aminotransferase and/or alanine aminotransferase compared to normal levels (relative risk (rr) 16.8 at 95 % confidence interval (ci) 5.0-56.3, р<0.001), pronounced changes in the lungs consistent with a ct-4 picture as shown by computed tomography (ct) (rr 13.4; 95 % ci 3.9-45.5, р<0.001), and mi/unstable angina during the stay in the hospital (rr 11.3; 95 % ci 1.4-90.6, р=0.023). |
2021-03-22 |
2023-08-13 |
Not clear |
Hadi Darvishi-Khezri, Hossein Karami, Mohammad Naderisorki, Mohammad Zahedi, Alireza Razavi, Mehrnoush Kosaryan, Aily Aliasgharia. Moderate to severe liver siderosis and raised AST are independent risk factors for vitamin D insufficiency in β-thalassemia patients. Scientific reports. vol 10. issue 1. 2021-03-16. PMID:33273639. |
the adjusted risks of moderate to severe liver siderosis and raised ast (aspartate aminotransferase) for vit-d insufficiency (< 30 ng/ml) were 2.31, 95% ci 1.38-3.89 and 2.62, 95% ci 1.43-4.79, respectively. |
2021-03-16 |
2023-08-13 |
Not clear |
Song Shen. Mean arterial pressure and arterial stiffness in Japanese population: a secondary analysis based on a cross-sectional study. Blood pressure monitoring. vol 25. issue 6. 2021-01-13. PMID:32701566. |
map is positively related with bapwv [effect size = 10.4; 95% confidence interval (ci), 9.2-11.6] after adjusting age, sex, bmi, smoking status, alcohol consumption, exercise, glutamyltranspeptidase, alanine aminotransferase, aspartate transaminase, total cholesterol, triglyceride, low-density lipoprotein, high-density lipoprotein cholesterol (hdl), fatty liver, fasting-blood glucose, uric acid, estimated glomerular filtration rate, and abi. |
2021-01-13 |
2023-08-13 |
human |
Xuezhen Zhao, Tian Chen, Bin Yang, Dejun Wang, Wen Sun, Yuwei Wang, Xiaodi Yang, Sheng Wen, Jingguang Li, Zhixiong Sh. Serum levels of novel brominated flame retardants (NBFRs) in residents of a major BFR-producing region: Occurrence, impact factors and the relationship to thyroid and liver function. Ecotoxicology and environmental safety. vol 208. 2021-01-08. PMID:33080422. |
for liver indicators, a 10-fold increment in the serum level of pbt was associated with decreased ln aspartate aminotransferase/alanine aminotransferase (ast/alt) level (-0.068) [95% ci: -0.129, -0.007]. |
2021-01-08 |
2023-08-13 |
human |
Yueh-Wei Liu, Chien-Chang Lu, Ching-Di Chang, Ko-Chao Lee, Hong Hwa Chen, Wen Shuo Yeh, Wang-Hseng Hu, Kai-Lung Tsai, Cheng-Hsi Yeh, Sin-Yong Wee, Shin-Min Yin, Chih-Chi Wang, Chao-Hung Hun. Prognostic value of sarcopenia in patients with colorectal liver metastases undergoing hepatic resection. Scientific reports. vol 10. issue 1. 2020-12-07. PMID:32296122. |
multinodularity (>3) (hr 1.750; 95% ci, 1.066-2.872; p = 0.027), high aspartate aminotransferase level (hr 1.024; 95% ci, 1.003-1.046; p = 0.025) and male gender (hr 1.688; 95% ci, 1.036-2.748; p = 0.035) were independent factors of rfs. |
2020-12-07 |
2023-08-13 |
Not clear |
Tülay Çevik Saldiran, Fatma Karantay Mutluay, İlker Yağci, Yusuf Yilma. Impact of aerobic training with and without whole-body vibration training on metabolic features and quality of life in non-alcoholic fatty liver disease patients. Annales d'endocrinologie. vol 81. issue 5. 2020-11-11. PMID:32768394. |
the decrease in serum aspartate transaminase was significantly greater in aerobic training without wbv (-14.81; 95% ci: -23.36 to -6.25; p: 0.029). |
2020-11-11 |
2023-08-13 |
Not clear |
Srinivas Puli, Muhammad Baig, Saqib Walaya. Gastrointestinal Symptoms and Elevation in Liver Enzymes in COVID-19 Infection: A Systematic Review and Meta-Analysis. Cureus. vol 12. issue 8. 2020-10-01. PMID:32983698. |
weighted mean difference of aspartate aminotransferase (ast), alanine aminotransferase (alt) in non-severe covid-19 patients was higher by 20.54 u/liter (95% ci = 19.95-21.13) and 21.38 u/liter (95% ci = 20.92-21.84) while that in severe patients was higher by 22.70 u/liter (95% ci = 19.09-26.45) and by 22.94 u/liter (95% ci = 20.46-25.42) respectively, as compared to general population. |
2020-10-01 |
2023-08-13 |
Not clear |