| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Romain Dacquin, Rachel A Davey, Catherine Laplace, Régis Levasseur, Howard A Morris, Steven R Goldring, Samuel Gebre-Medhin, Deborah L Galson, Jeffrey D Zajac, Gérard Karsent. Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo. The Journal of cell biology. vol 164. issue 4. 2004-09-20. PMID:14970190. |
amylin is a member of the calcitonin family of hormones cosecreted with insulin by pancreatic beta cells. |
2004-09-20 |
2023-08-12 |
mouse |
| Nicholas A Peppas, Kristy M Wood, James O Blanchett. Hydrogels for oral delivery of therapeutic proteins. Expert opinion on biological therapy. vol 4. issue 6. 2004-08-24. PMID:15174970. |
emphasis has been given to the molecular design of new carriers for the delivery of insulin, calcitonin and various types of interferons for the treatment of diabetes, osteoporosis, multiple sclerosis and cancer. |
2004-08-24 |
2023-08-12 |
Not clear |
| Zhiying Wang, Qiang Zhan. Transport of proteins and peptides across human cultured alveolar A549 cell monolayer. International journal of pharmaceutics. vol 269. issue 2. 2004-05-11. PMID:14706256. |
an in vitro cultured monolayer system of alveolar epithelial cells was used as a model to investigate the transport pathway of the peptides and proteins, salmon calcitonin (sct), insulin (ins), recombinant hirudin (rhav2), and recombinant human growth hormone (rhgh), in pulmonary epithelium. |
2004-05-11 |
2023-08-12 |
human |
| Johan H Koeslag, Peter T Saunders, Elmarie Terblanch. A reappraisal of the blood glucose homeostat which comprehensively explains the type 2 diabetes mellitus-syndrome X complex. The Journal of physiology. vol 549. issue Pt 2. 2004-01-22. PMID:12717005. |
insulin and glucagon, or calcitonin and parathyroid hormone) cannot operate on the same controlled variable, unless there is some form of mutual inhibition. |
2004-01-22 |
2023-08-12 |
Not clear |
| Katerina Zajickova, Ivana Zofkov. Osteoporosis: genetic analysis of multifactorial disease. Endocrine regulations. vol 37. issue 1. 2004-01-07. PMID:12916320. |
linkage analysis and association studies with numerous dna markers (single nucleotide polymorphisms or microsatellites) have analysed several bone-related candidate genes encoding vitamin d, calcium-sensing, calcitonin and estrogen alpha receptors, insulin growth factor i, collagen type i alpha 1 chain and others. |
2004-01-07 |
2023-08-12 |
Not clear |
| Fakhrul Ahsan, John J Arnold, Elias Meezan, Dennis J Pillio. Sucrose cocoate, a component of cosmetic preparations, enhances nasal and ocular peptide absorption. International journal of pharmaceutics. vol 251. issue 1-2. 2003-07-16. PMID:12527189. |
in order to determine its potential utility in enhancing nasal and ocular drug delivery, absorption studies were performed in anesthetized sprague-dawley male rats with calcitonin and insulin, two distinct therapeutic peptides. |
2003-07-16 |
2023-08-12 |
rat |
| Rakhi B Shah, Fakhrul Ahsan, Mansoor A Kha. Oral delivery of proteins: progress and prognostication. Critical reviews in therapeutic drug carrier systems. vol 19. issue 2. 2003-03-12. PMID:12197608. |
the important therapeutic proteins and peptides being explored for oral delivery include insulin, calcitonin, interferons, human growth hormone, glucagons, gonadotropin-releasing hormones, enkephalins, vaccines, enzymes, hormone analogs, and enzyme inhibitors. |
2003-03-12 |
2023-08-12 |
human |
| C Hamme. Xenotransplantation for liver therapy or: Can porcine hepatocytes generate physiological functions sufficient for a human patient in ALF? The International journal of artificial organs. vol 25. issue 10. 2003-02-21. PMID:12456045. |
only very conservative molecules, like for example insulin or calcitonin function properly in both species, while others such as complement, albumin and erythropoietin do not fulfill their task properly or not at all. |
2003-02-21 |
2023-08-12 |
human |
| Victor J Hrub. Designing peptide receptor agonists and antagonists. Nature reviews. Drug discovery. vol 1. issue 11. 2002-11-26. PMID:12415245. |
although there are numerous exceptions, such as insulin, oxytocin and calcitonin, most ligands are not used directly as drugs, and often the most useful ligands for therapy would be analogues that act as antagonists of the native ligands. |
2002-11-26 |
2023-08-12 |
Not clear |
| G B Hubbard, K E Steele, K J Davis, M M Lelan. Spontaneous pancreatic islet amyloidosis in 40 baboons. Journal of medical primatology. vol 31. issue 2. 2002-07-30. PMID:12110051. |
sections of paraffin-embedded tissues were evaluated for amyloid with hematoxylin and eosin (he) and congo red (cr) staining, and using immunohistochemistry for human islet amyloid polypeptide (iapp), calcitonin gene-related peptide (cgrp), glucagon, pancreatic polypeptide (pp), somatostatin (ss), and porcine insulin. |
2002-07-30 |
2023-08-12 |
human |
| A Yamamot. [Improvement of transmucosal absorption of biologically active peptide drugs]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 121. issue 12. 2002-01-15. PMID:11766407. |
in this study, we demonstrated that the transmucosal absorption of various peptides including insulin, calcitonin, tetragastrin and thyrotropin releasing hormone (trh) could be improved by the use of these approaches. |
2002-01-15 |
2023-08-12 |
Not clear |
| R U Agu, M I Ugwoke, M Armand, R Kinget, N Verbek. The lung as a route for systemic delivery of therapeutic proteins and peptides. Respiratory research. vol 2. issue 4. 2002-01-10. PMID:11686885. |
current efforts to overcome these difficulties in order to deliver metabolic hormones (insulin, calcitonin, thyroid-stimulating hormone [tsh], follicle-stimulating hormone [fsh] and growth hormones) systemically, to induce systemic responses (immunoglobulins, cyclosporin a [csa], recombinant-methionyl human granulocyte colony-stimulating factor [r-hug-csf], pancreatic islet autoantigen) and to modulate other biological processes via the lung are reviewed. |
2002-01-10 |
2023-08-12 |
human |
| B A Baldo, A E Kelle. Amylin infusion into rat nucleus accumbens potently depresses motor activity and ingestive behavior. American journal of physiology. Regulatory, integrative and comparative physiology. vol 281. issue 4. 2001-10-18. PMID:11557632. |
amylin, a calcitonin gene-related peptide-like peptide coreleased with insulin, exerts anorexic effects on central administration. |
2001-10-18 |
2023-08-12 |
rat |
| b' I Zofkov\\xc3\\xa1, R Bahbouh, B Bendlov\\xc3\\xa. Systemic insulin-like growth factor-I, insulin and vitamin D status in relation to age-associated bone loss in women. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 109. issue 5. 2001-09-27. PMID:11507650.' |
after adjustment for age, body mass index, serum pth, vitamin d status and calcitonin levels, neither igf-i nor insulin levels could be significantly related to bmd at the spine or hip. |
2001-09-27 |
2023-08-12 |
human |
| Y Miyamoto, M Yoneda, A Morikawa, H Itoh, I Makin. Gastric neuropeptides and gastric motor abnormality in streptozotocin-induced diabetic rats: observation for four weeks after streptozotocin. Digestive diseases and sciences. vol 46. issue 8. 2001-09-06. PMID:11508655. |
insulin treatment reversed alterations of gastric emptying and calcitonin gene-related peptide content. |
2001-09-06 |
2023-08-12 |
rat |
| Y Wang, A Xu, J Ye, E W Kraegen, C A Tse, G J Coope. Alteration in phosphorylation of P20 is associated with insulin resistance. Diabetes. vol 50. issue 8. 2001-08-23. PMID:11473044. |
we have recently identified a small phosphoprotein, p20, as a common intracellular target for insulin and several of its antagonists, including amylin, epinephrine, and calcitonin gene-related peptide. |
2001-08-23 |
2023-08-12 |
rat |
| H Kawasaki, S Kuroda, Y Mimak. [Vascular effects of insulin]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 115. issue 5. 2000-08-07. PMID:10872180. |
an increase in cyclic amp levels is induced by insulin, via activation of insulin receptors, beta-adrenoceptors and calcitonin gene-related peptide receptors. |
2000-08-07 |
2023-08-12 |
Not clear |
| M Yamaguch. Role of regucalcin in calcium signaling. Life sciences. vol 66. issue 19. 2000-05-18. PMID:10809175. |
hepatic regucalcin mrna expression has been shown to be stimulated by various factors including calcium, calcitonin, insulin, and estrogen in rats. |
2000-05-18 |
2023-08-12 |
rat |
| A Bernkop-Schnürc. Chitosan and its derivatives: potential excipients for peroral peptide delivery systems. International journal of pharmaceutics. vol 194. issue 1. 2000-03-16. PMID:10601680. |
based on these unique features, the co-administration of chitosan and its derivatives leads to a strongly improved bioavailability of many perorally given peptide drugs such as insulin, calcitonin and buserelin. |
2000-03-16 |
2023-08-12 |
Not clear |
| D Chatelain, B Chailley-Heu, B Terris, G Molas, A Le Caë, V Vilgrain, J Belghiti, C Degott, J F Flejo. The ciliated hepatic foregut cyst, an unusual bronchiolar foregut malformation: a histological, histochemical, and immunohistochemical study of 7 cases. Human pathology. vol 31. issue 2. 2000-03-03. PMID:10685641. |
the immunohistochemical study showed that endocrine cells were present within the cyst epithelium, positive for chromogranin, synaptophysin, bombesin, and calcitonin, and negative for serotonin, somatostatin, glucagon, insulin, gastrin, and pancreatic polypeptide. |
2000-03-03 |
2023-08-12 |
Not clear |